Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

Navigation
Downloads

Results for Stat2

Z-value: 1.11

Motif logo

Transcription factors associated with Stat2

Gene Symbol Gene ID Gene Info
ENSRNOG00000031081 signal transducer and activator of transcription 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat2rn6_v1_chr7_+_2694440_2694440-0.642.5e-01Click!

Activity profile of Stat2 motif

Sorted Z-values of Stat2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_47482961 0.57 ENSRNOT00000001600
2'-5' oligoadenylate synthetase-like 2
chr1_-_214252456 0.51 ENSRNOT00000023504
interferon regulatory factor 7
chr17_+_9236249 0.47 ENSRNOT00000015878
TIFA inhibitor
chr1_+_53220397 0.44 ENSRNOT00000089989

chr2_+_248178389 0.39 ENSRNOT00000037339
guanylate binding protein 5
chr10_+_64737022 0.39 ENSRNOT00000017071
ENSRNOT00000093232
ENSRNOT00000017042
ENSRNOT00000093244
galectin 9
chr20_+_3979035 0.35 ENSRNOT00000000529
transporter 1, ATP binding cassette subfamily B member
chr15_+_60084918 0.32 ENSRNOT00000012632
epithelial stromal interaction 1
chr2_-_256915563 0.32 ENSRNOT00000084873
ENSRNOT00000029990
interferon-induced protein 44
chr9_-_44483655 0.31 ENSRNOT00000024959
microtubule interacting and trafficking domain containing 1
chr10_-_70744315 0.30 ENSRNOT00000014865
C-C motif chemokine ligand 5
chr2_+_166475070 0.29 ENSRNOT00000071111

chr5_-_126096068 0.28 ENSRNOT00000036793

chr4_+_153805993 0.26 ENSRNOT00000056174
ubiquitin specific peptidase 18
chr12_+_41200718 0.24 ENSRNOT00000038426
ENSRNOT00000048450
ENSRNOT00000067176
2'-5' oligoadenylate synthetase 1A
chr11_+_38035450 0.23 ENSRNOT00000083067
MX dynamin like GTPase 2
chr1_-_198008893 0.23 ENSRNOT00000025950
interleukin 27
chr1_+_142679345 0.23 ENSRNOT00000034267
zinc finger and SCAN domain containing 2
chr1_+_101517714 0.22 ENSRNOT00000028423
pleckstrin homology domain containing A4
chr9_-_44560837 0.22 ENSRNOT00000090870
microtubule interacting and trafficking domain containing 1
chr1_+_1545134 0.22 ENSRNOT00000044523

chr2_-_98610368 0.22 ENSRNOT00000011641
zinc finger homeobox 4
chr3_-_37445907 0.21 ENSRNOT00000006172
RNA binding motif protein 43
chr11_+_68105369 0.21 ENSRNOT00000046888
poly (ADP-ribose) polymerase family, member 14
chrX_-_105390580 0.21 ENSRNOT00000077547
Bruton tyrosine kinase
chr10_+_58860940 0.20 ENSRNOT00000056551
ENSRNOT00000074523
XIAP associated factor-1
chr9_-_92616165 0.20 ENSRNOT00000056995
SP110 nuclear body protein
chr15_-_61772516 0.19 ENSRNOT00000015605
ENSRNOT00000093399
WW domain binding protein 4
chr4_-_66899914 0.19 ENSRNOT00000011481
poly (ADP-ribose) polymerase family, member 12
chr5_-_173626248 0.19 ENSRNOT00000039263
ISG15 ubiquitin-like modifier
chr2_+_248276709 0.19 ENSRNOT00000068683
guanylate binding protein 2
chr10_-_38969501 0.19 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr14_+_17210733 0.19 ENSRNOT00000003075
C-X-C motif chemokine ligand 10
chr13_+_44475970 0.18 ENSRNOT00000024602
ENSRNOT00000091645
cyclin T2
chr20_-_4542073 0.18 ENSRNOT00000000477
complement factor B
chr10_-_34221928 0.18 ENSRNOT00000045545
immunity-related GTPase M
chr7_-_36000906 0.18 ENSRNOT00000011178
plexin C1
chr2_+_216863428 0.17 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr5_+_159734838 0.17 ENSRNOT00000079905
REM2 and RAB-like small GTPase 1
chr4_+_179398621 0.16 ENSRNOT00000049474
ENSRNOT00000067506
lymphoid-restricted membrane protein
chr10_-_88163712 0.16 ENSRNOT00000005382
ENSRNOT00000084493
keratin 17
chr16_-_19942343 0.16 ENSRNOT00000087162
ENSRNOT00000091906
bone marrow stromal cell antigen 2
chr15_+_34282936 0.16 ENSRNOT00000026364
interferon regulatory factor 9
chr17_-_32661865 0.15 ENSRNOT00000022194
serpin family B member 9
chr17_-_84247038 0.15 ENSRNOT00000068553
nebulette
chr13_+_48790767 0.15 ENSRNOT00000087504
ELK4, ETS transcription factor
chr20_-_3166569 0.14 ENSRNOT00000091390

chr2_-_243224883 0.14 ENSRNOT00000014139
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr20_-_3978845 0.13 ENSRNOT00000000532
proteasome subunit beta 9
chr11_+_38035611 0.13 ENSRNOT00000087603
ENSRNOT00000002695
MX dynamin like GTPase 2
chr17_-_47653989 0.13 ENSRNOT00000072833
LRRGT00094
chr18_+_55685613 0.13 ENSRNOT00000040116
similar to cDNA sequence BC023105
chr11_+_67757928 0.13 ENSRNOT00000039215
deltex E3 ubiquitin ligase 3L
chr2_+_52358097 0.13 ENSRNOT00000037659
transmembrane protein 267
chr8_-_63034226 0.12 ENSRNOT00000043434
promyelocytic leukemia
chr5_+_159735008 0.12 ENSRNOT00000064310
REM2 and RAB-like small GTPase 1
chr1_+_252894663 0.12 ENSRNOT00000054757
interferon-induced protein with tetratricopeptide repeats 2
chr4_-_120408232 0.12 ENSRNOT00000073269
40S ribosomal protein S25-like
chr1_+_30681681 0.12 ENSRNOT00000015395
R-spondin 3
chr13_+_48790951 0.12 ENSRNOT00000090233
ELK4, ETS transcription factor
chr8_+_21663325 0.11 ENSRNOT00000027749
ubiquitin-like 5
chr3_-_171286413 0.11 ENSRNOT00000008365
ENSRNOT00000081036
Z-DNA binding protein 1
chr1_+_84009268 0.11 ENSRNOT00000057230
ENSRNOT00000081121
similar to FLJ41131 protein
chr16_+_50111306 0.11 ENSRNOT00000019302
cytochrome P450, family 4, subfamily v, polypeptide 3
chr1_+_64046377 0.11 ENSRNOT00000085010
transmembrane channel-like 4
chr5_-_58198782 0.11 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr4_+_102351036 0.11 ENSRNOT00000079277

chr5_-_135472116 0.11 ENSRNOT00000022170
nuclear autoantigenic sperm protein
chr4_-_88649216 0.11 ENSRNOT00000058626
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr15_-_93748742 0.11 ENSRNOT00000093370
MYC binding protein 2, E3 ubiquitin protein ligase
chr13_-_52514875 0.10 ENSRNOT00000064758
neuron navigator 1
chr1_-_53520788 0.10 ENSRNOT00000060121
G protein-coupled receptor 31
chr3_+_72460889 0.10 ENSRNOT00000012209
tankyrase 1 binding protein 1
chr1_-_197886759 0.10 ENSRNOT00000074274
SH2B adaptor protein 1
chr10_-_36322356 0.10 ENSRNOT00000000248
zinc finger protein 354C
chr3_-_163814799 0.10 ENSRNOT00000055127
zinc finger, NFX1-type containing 1
chr20_+_3242470 0.10 ENSRNOT00000078110
ENSRNOT00000041502
RT1 class I, locus T24, gene 2
RT1 class I, locus T24, gene 1
chr2_+_209097927 0.10 ENSRNOT00000023807
DENN domain containing 2D
chr7_-_139907640 0.10 ENSRNOT00000045473
zinc finger protein 641
chr6_+_127327959 0.10 ENSRNOT00000012296
interferon, alpha-inducible protein 27
chr8_+_33239139 0.10 ENSRNOT00000011589
Rho GTPase activating protein 32
chr10_+_89358376 0.10 ENSRNOT00000028067
interferon-induced protein 35
chr10_-_57064600 0.10 ENSRNOT00000032926
C-X-C motif chemokine ligand 16
chr13_+_60435946 0.09 ENSRNOT00000004342
Beta-1,3-galactosyltransferase 2
chr4_+_67165883 0.09 ENSRNOT00000012280
RAB19, member RAS oncogene family
chr13_+_89386023 0.09 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr10_+_76343847 0.09 ENSRNOT00000055674
tripartite motif-containing 25
chr18_+_55576239 0.09 ENSRNOT00000050063
interferon-inducible GTPase 1-like
chr1_+_169433539 0.09 ENSRNOT00000055210
tripartite motif-containing 34
chr18_+_56364620 0.09 ENSRNOT00000068535
ENSRNOT00000086033
platelet derived growth factor receptor beta
chr14_+_19319299 0.09 ENSRNOT00000086542
ankyrin repeat domain 17
chr8_+_116754178 0.09 ENSRNOT00000068295
ENSRNOT00000084429
ubiquitin-like modifier activating enzyme 7
chr17_+_36334147 0.08 ENSRNOT00000050261
E2F transcription factor 3
chr7_-_117300662 0.08 ENSRNOT00000006376
poly (ADP-ribose) polymerase family, member 10
chr1_+_255185629 0.08 ENSRNOT00000083002
HECT domain E3 ubiquitin protein ligase 2
chr15_+_34256071 0.08 ENSRNOT00000025887
proteasome activator subunit 1
chr13_+_93684437 0.08 ENSRNOT00000005005
kynurenine 3-monooxygenase
chr6_+_135866739 0.08 ENSRNOT00000013460
exocyst complex component 3-like 4
chr1_+_215628785 0.08 ENSRNOT00000054864
lymphocyte-specific protein 1
chr3_-_72171078 0.07 ENSRNOT00000009817
serpin family G member 1
chr9_+_119517101 0.07 ENSRNOT00000020476
lipin 2
chr4_-_120414118 0.07 ENSRNOT00000072795
40S ribosomal protein S25-like
chr3_+_161519743 0.07 ENSRNOT00000055148
CD40 molecule
chr3_-_147809658 0.07 ENSRNOT00000085995
ENSRNOT00000045314
RANBP2-type and C3HC4-type zinc finger containing 1
chr16_-_85306366 0.07 ENSRNOT00000089650
tumor necrosis factor superfamily member 13b
chr3_-_48604097 0.06 ENSRNOT00000009620
interferon induced with helicase C domain 1
chr5_-_56536772 0.06 ENSRNOT00000060765
DEXD/H-box helicase 58
chr7_+_132857628 0.06 ENSRNOT00000005438
leucine-rich repeat kinase 2
chr3_+_114087287 0.06 ENSRNOT00000023017
beta-2 microglobulin
chr5_-_58183017 0.06 ENSRNOT00000020982
C-C motif chemokine ligand 19
chr10_+_90377103 0.06 ENSRNOT00000040472
granulin precursor
chr10_-_107424710 0.06 ENSRNOT00000004320
galectin 3 binding protein
chr7_-_144837583 0.06 ENSRNOT00000055289
chromobox 5
chr12_+_23514981 0.06 ENSRNOT00000001937
Prkr interacting protein 1 (IL11 inducible)
chr12_+_41341417 0.06 ENSRNOT00000072024
ENSRNOT00000091460
2'-5' oligoadenylate synthetase 2
chr10_-_88611105 0.06 ENSRNOT00000024718
DEXH-box helicase 58
chrX_+_11648989 0.06 ENSRNOT00000041003
BCL6 co-repressor
chr1_+_265298868 0.05 ENSRNOT00000023278
deleted in primary ciliary dyskinesia
chr2_-_210550490 0.05 ENSRNOT00000081835
ENSRNOT00000025222
ENSRNOT00000086403
colony stimulating factor 1
chr8_+_128133431 0.05 ENSRNOT00000020174
exo/endonuclease G
chr10_+_90376933 0.05 ENSRNOT00000028557
granulin precursor
chr7_-_140600818 0.05 ENSRNOT00000082375
limb development membrane protein 1-like
chr15_+_36809361 0.05 ENSRNOT00000076667
poly (ADP-ribose) polymerase family, member 4
chr18_+_64114933 0.05 ENSRNOT00000022364
melanocortin 5 receptor
chr1_-_167093560 0.05 ENSRNOT00000027301
interleukin 18 binding protein
chr5_+_113725717 0.05 ENSRNOT00000032248
TEK receptor tyrosine kinase
chrX_-_14910727 0.05 ENSRNOT00000085079
ENSRNOT00000030146
SSX family member 1
chr8_-_62948720 0.05 ENSRNOT00000075476
immunoglobulin superfamily containing leucine-rich repeat
chr12_-_44962656 0.04 ENSRNOT00000001499
WD repeat and SOCS box-containing 2
chr14_+_113530470 0.04 ENSRNOT00000004919
polyribonucleotide nucleotidyltransferase 1
chr2_+_263212051 0.04 ENSRNOT00000089396
neuronal growth regulator 1
chr7_+_11878943 0.04 ENSRNOT00000025634
MOB kinase activator 3A
chr20_+_3269284 0.04 ENSRNOT00000089044
RT1 class I, locus T24, gene 1
chr8_-_85803433 0.04 ENSRNOT00000081544
ENSRNOT00000073286
Mab-21 domain containing 1
chr10_+_55924938 0.04 ENSRNOT00000087003
ENSRNOT00000057079
trafficking protein particle complex 1
chr1_-_252922486 0.04 ENSRNOT00000076802
interferon-induced protein with tetratricopeptide repeats 1B-like
chr9_-_54351339 0.04 ENSRNOT00000080522
signal transducer and activator of transcription 1
chr13_+_37400476 0.04 ENSRNOT00000003435
coiled-coil domain containing 93
chr5_+_61564864 0.04 ENSRNOT00000085738
tudor domain containing 7
chr2_-_28799266 0.04 ENSRNOT00000089293
transmembrane protein 171
chr5_+_61565439 0.04 ENSRNOT00000089938
tudor domain containing 7
chr1_-_84353725 0.04 ENSRNOT00000057177
phospholipase D family, member 3
chr10_+_57064482 0.04 ENSRNOT00000046807
zinc finger, MYND-type containing 15
chr7_-_144837395 0.04 ENSRNOT00000089024
chromobox 5
chr3_-_2770620 0.03 ENSRNOT00000008253
Tnf receptor-associated factor 2
chr12_-_41266430 0.03 ENSRNOT00000001853
ENSRNOT00000081108
2-5 oligoadenylate synthetase 1B
chr1_-_102849430 0.03 ENSRNOT00000086856
serum amyloid A4
chr6_-_21135880 0.03 ENSRNOT00000051239
RAS guanyl releasing protein 3
chr1_+_72810545 0.03 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr1_+_64114721 0.03 ENSRNOT00000080466
transmembrane channel-like 4
chr12_-_47456894 0.03 ENSRNOT00000001570
2'-5'-oligoadenylate synthetase-like
chr1_+_255842783 0.03 ENSRNOT00000023562
membrane associated ring-CH-type finger 5
chr10_-_5253336 0.03 ENSRNOT00000085310
class II, major histocompatibility complex, transactivator
chr10_-_110431792 0.03 ENSRNOT00000054922
hypothetical protein LOC619574
chr1_+_166125474 0.03 ENSRNOT00000091822
FCH and double SH3 domains 2
chrX_+_54390733 0.03 ENSRNOT00000004977
similar to chromosome X open reading frame 21
chr13_-_83917001 0.03 ENSRNOT00000004387
ENSRNOT00000082422
RCSD domain containing 1
chr7_-_118933812 0.03 ENSRNOT00000031951
apolipoprotein L 9a
chr5_+_156603725 0.03 ENSRNOT00000075852
heterochromatin protein 1, binding protein 3
chr8_+_126411829 0.02 ENSRNOT00000013450
5-azacytidine induced 2
chr5_+_128450680 0.02 ENSRNOT00000010700
thioredoxin domain containing 12
chr2_-_190100276 0.02 ENSRNOT00000015351
S100 calcium binding protein A9
chr2_+_189062443 0.02 ENSRNOT00000028181
adenosine deaminase, RNA-specific
chr5_+_141572536 0.02 ENSRNOT00000023514
Ras-related GTP binding C
chr9_-_88357182 0.02 ENSRNOT00000041176
collagen type IV alpha 4 chain
chr8_-_108261021 0.02 ENSRNOT00000040710
40S ribosomal protein S25-like
chr16_-_71203609 0.02 ENSRNOT00000088458
nuclear receptor binding SET domain protein 3
chr1_+_72756809 0.02 ENSRNOT00000082423
protein phosphatase 6, regulatory subunit 1
chr5_-_131860637 0.02 ENSRNOT00000064569
ENSRNOT00000080242
solute carrier family 5 member 9
chr4_-_150485781 0.02 ENSRNOT00000008763
zinc finger protein 248
chr4_+_99449111 0.02 ENSRNOT00000010253
charged multivesicular body protein 3
chr12_+_42343123 0.02 ENSRNOT00000043279
2 ' -5 ' oligoadenylate synthetase 1I
chr10_+_104377748 0.02 ENSRNOT00000080714
LLGL2, scribble cell polarity complex component
chr1_+_255564409 0.02 ENSRNOT00000081786
B-TFIID TATA-box binding protein associated factor 1
chr4_-_67162808 0.01 ENSRNOT00000011915
solute carrier family 37, member 3
chrX_-_64702441 0.01 ENSRNOT00000051132
APC membrane recruitment protein 1
chr20_+_8325041 0.01 ENSRNOT00000000640
cap methyltransferase 1
chr11_+_67082193 0.01 ENSRNOT00000003129
CD86 molecule
chr13_+_89385859 0.01 ENSRNOT00000047434
Fc fragment of IgG receptor IIIa
chr6_-_1466201 0.01 ENSRNOT00000089185
eukaryotic translation initiation factor 2-alpha kinase 2
chr10_+_43613931 0.01 ENSRNOT00000039335
interferon gamma induced GTPase
chr7_+_122979021 0.01 ENSRNOT00000085707
zinc finger CCCH-type containing 7B
chrX_-_154722220 0.01 ENSRNOT00000089743
ENSRNOT00000087893
fragile X mental retardation 1
chr1_+_277190964 0.01 ENSRNOT00000080511
caspase 7
chr9_+_53004499 0.01 ENSRNOT00000059233
asparagine synthetase domain containing 1
chrX_-_153039372 0.01 ENSRNOT00000085250
paraneoplastic Ma antigen family member 5
chr9_-_26932201 0.01 ENSRNOT00000017081
minichromosome maintenance complex component 3
chr5_-_24489468 0.01 ENSRNOT00000081395
integrator complex subunit 8
chr4_-_120041238 0.01 ENSRNOT00000073799
40S ribosomal protein S25-like
chr2_+_148722231 0.01 ENSRNOT00000018022
eukaryotic translation initiation factor 2A
chr19_+_33160180 0.01 ENSRNOT00000016422
POU class 4 homeobox 2
chr1_-_24056373 0.01 ENSRNOT00000015566
solute carrier family 2 member 12
chr17_+_43661222 0.01 ENSRNOT00000022881
ENSRNOT00000022809
ENSRNOT00000022810
hemochromatosis
chr1_+_219439953 0.01 ENSRNOT00000025282
protein phosphatase 1 catalytic subunit alpha
chr4_-_58250798 0.00 ENSRNOT00000048436
Kruppel-like factor 14
chr20_-_5476193 0.00 ENSRNOT00000044975
TAP binding protein
chr16_+_18690649 0.00 ENSRNOT00000015190
methionine adenosyltransferase 1A
chr5_+_154077944 0.00 ENSRNOT00000031512
interleukin 22 receptor subunit alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.1 0.4 GO:0046967 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
0.1 0.3 GO:0042509 CD8-positive, alpha-beta T cell extravasation(GO:0035697) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.4 GO:2001190 regulation of natural killer cell degranulation(GO:0043321) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.2 GO:2000424 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 0.2 GO:0019086 late viral transcription(GO:0019086)
0.1 0.2 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344) cellular response to molecule of fungal origin(GO:0071226)
0.1 0.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.4 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.4 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.1 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:1901423 response to benzene(GO:1901423)
0.0 0.2 GO:0052490 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.1 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.0 0.1 GO:0070212 regulation of chromatin assembly(GO:0010847) protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0038086 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499) regulation of peroxidase activity(GO:2000468)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:1904139 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.0 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.0 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.0 GO:0045025 mitochondrial degradosome(GO:0045025)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0019767 IgE receptor activity(GO:0019767)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade