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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Spic

Z-value: 0.88

Motif logo

Transcription factors associated with Spic

Gene Symbol Gene ID Gene Info
ENSRNOG00000005720 Spi-C transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spicrn6_v1_chr7_-_29233392_292333920.415.0e-01Click!

Activity profile of Spic motif

Sorted Z-values of Spic motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_5163247 0.29 ENSRNOT00000001135
allograft inflammatory factor 1
chr6_+_53401109 0.29 ENSRNOT00000014763
twist family bHLH transcription factor 1
chr1_-_101236065 0.28 ENSRNOT00000066834
CD37 molecule
chr8_+_21663325 0.25 ENSRNOT00000027749
ubiquitin-like 5
chr13_-_89606326 0.25 ENSRNOT00000029179
Fc fragment of IgE receptor Ig
chr4_-_155923079 0.23 ENSRNOT00000013308
C-type lectin domain family 4, member A3
chr13_+_89386023 0.23 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr5_-_155258392 0.21 ENSRNOT00000017065
complement C1q C chain
chr2_-_28799266 0.20 ENSRNOT00000089293
transmembrane protein 171
chr5_-_155252003 0.19 ENSRNOT00000017060
complement C1q B chain
chr8_+_81949877 0.19 ENSRNOT00000030221
cAMP-regulated phosphoprotein 19-like
chr1_-_146289465 0.19 ENSRNOT00000017362
abhydrolase domain containing 17C
chr9_+_81518176 0.19 ENSRNOT00000078317
ENSRNOT00000019265
ENSRNOT00000088246
ENSRNOT00000084682
actin related protein 2/3 complex, subunit 2
chr13_-_89433815 0.19 ENSRNOT00000091541
Fc fragment of IgG receptor IIb
chr1_+_219481575 0.18 ENSRNOT00000025507
DNA polymerase delta 4, accessory subunit
chr1_-_13175876 0.18 ENSRNOT00000084870
ABRA C-terminal like
chr1_-_281101438 0.18 ENSRNOT00000012734
RAB11 family interacting protein 2
chr6_+_26836216 0.18 ENSRNOT00000077903
ENSRNOT00000011373
oligosaccharyltransferase complex subunit 4, non-catalytic
chr10_-_57436368 0.18 ENSRNOT00000056608
SLP adaptor and CSK interacting membrane protein
chr4_+_145330457 0.18 ENSRNOT00000011937
actin related protein 2/3 complex, subunit 4
chr5_+_149047681 0.17 ENSRNOT00000015198
lysosomal protein transmembrane 5
chr4_-_157252104 0.17 ENSRNOT00000082739
protein tyrosine phosphatase, non-receptor type 6
chr17_+_80250521 0.17 ENSRNOT00000023446
phosphotriesterase related
chr4_-_120414118 0.17 ENSRNOT00000072795
40S ribosomal protein S25-like
chr7_+_58814805 0.17 ENSRNOT00000005909
tetraspanin 8
chr6_+_137323713 0.17 ENSRNOT00000029017
phospholipase D family, member 4
chr1_-_47502952 0.16 ENSRNOT00000025580
T-cell activation RhoGTPase activating protein
chr1_+_215628785 0.16 ENSRNOT00000054864
lymphocyte-specific protein 1
chr19_+_26194465 0.16 ENSRNOT00000087627
ENSRNOT00000065931
WD repeat domain 83 opposite strand
chr1_+_87938042 0.16 ENSRNOT00000027837
mitogen activated protein kinase kinase kinase kinase 1
chr13_+_89385859 0.16 ENSRNOT00000047434
Fc fragment of IgG receptor IIIa
chr8_-_96547568 0.16 ENSRNOT00000078343
similar to RIKEN cDNA 4930579C12 gene
chr9_-_52830457 0.16 ENSRNOT00000073557
solute carrier family 40 member 1
chr8_-_117820413 0.15 ENSRNOT00000075819
translation machinery associated 7 homolog
chr1_-_165997751 0.15 ENSRNOT00000050227
pyrimidinergic receptor P2Y6
chr1_-_198120061 0.15 ENSRNOT00000026231
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr11_-_67756799 0.15 ENSRNOT00000030975
poly (ADP-ribose) polymerase family, member 9
chr2_-_185303610 0.15 ENSRNOT00000093479
ENSRNOT00000046286
protease, serine 48
chr14_-_100184192 0.15 ENSRNOT00000007044
pleckstrin
chr10_+_86819472 0.14 ENSRNOT00000081424
cell division cycle 6
chr4_-_99746560 0.14 ENSRNOT00000012021
mitochondrial ribosomal protein L35
chr2_-_209537087 0.14 ENSRNOT00000024344
Cd53 molecule
chr19_-_15540773 0.14 ENSRNOT00000022359
lysophosphatidylcholine acyltransferase 2
chr10_+_55924938 0.14 ENSRNOT00000087003
ENSRNOT00000057079
trafficking protein particle complex 1
chr2_+_234375315 0.14 ENSRNOT00000071270
elongation of very long chain fatty acids protein 6-like
chr20_-_4368693 0.14 ENSRNOT00000000501
ring finger protein 5
chr3_+_160467552 0.13 ENSRNOT00000066657
serine/threonine kinase 4
chr15_-_34352673 0.13 ENSRNOT00000064916
neural precursor cell expressed, developmentally down-regulated 8
chr9_-_26932201 0.13 ENSRNOT00000017081
minichromosome maintenance complex component 3
chr12_+_24148567 0.13 ENSRNOT00000077378
ENSRNOT00000045157
C-C motif chemokine ligand 24
chr5_-_57896475 0.13 ENSRNOT00000017903
similar to testes development-related NYD-SP22 isoform 1
chr13_+_99663150 0.12 ENSRNOT00000036705
cornichon family AMPA receptor auxiliary protein 3
chr1_+_215609645 0.12 ENSRNOT00000076140
ENSRNOT00000027487
troponin I2, fast skeletal type
chr10_-_3321404 0.12 ENSRNOT00000093722
ENSRNOT00000003284
pyridoxal-dependent decarboxylase domain containing 1
chr11_+_31560530 0.12 ENSRNOT00000061345
interleukin 10 receptor subunit beta
chr1_-_260254600 0.12 ENSRNOT00000019014
B-cell linker
chr7_-_12899004 0.12 ENSRNOT00000011086
granzyme M
chr4_-_120041238 0.12 ENSRNOT00000073799
40S ribosomal protein S25-like
chr2_+_55835151 0.12 ENSRNOT00000018634
FYN binding protein
chr7_+_78005232 0.12 ENSRNOT00000005803
DDB1 and CUL4 associated factor 13
chr3_+_160391106 0.12 ENSRNOT00000016981
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr1_-_277181345 0.12 ENSRNOT00000038017
ENSRNOT00000038038
nebulin-related anchoring protein
chr2_-_198002625 0.11 ENSRNOT00000091888
cDNA sequence BC028528
chr6_-_27323992 0.11 ENSRNOT00000013198
similar to RIKEN cDNA 1700001C02
chr1_+_215610368 0.11 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr2_+_210045161 0.11 ENSRNOT00000024455
solute carrier family 16, member 4
chr9_+_81518584 0.11 ENSRNOT00000084309
actin related protein 2/3 complex, subunit 2
chr1_-_101118825 0.11 ENSRNOT00000066328
ribosomal protein S11
chr4_-_170932618 0.10 ENSRNOT00000007779
Rho GDP dissociation inhibitor beta
chr6_+_129609375 0.10 ENSRNOT00000083732
poly (A) polymerase alpha
chr5_-_38923095 0.10 ENSRNOT00000009146

chr20_+_5441876 0.10 ENSRNOT00000092476
ribosomal protein S18
chr12_-_39667849 0.10 ENSRNOT00000011499
actin related protein 2/3 complex, subunit 3
chr19_-_55257876 0.10 ENSRNOT00000017564
cytochrome b-245 alpha chain
chr20_+_4530342 0.10 ENSRNOT00000076352
ENSRNOT00000000478
ENSRNOT00000075925
negative elongation factor complex member E
chr10_-_109630005 0.10 ENSRNOT00000075206
oxidoreductase-like domain containing 1
chr1_+_242959488 0.10 ENSRNOT00000015668
dedicator of cytokinesis 8
chr7_+_11784341 0.10 ENSRNOT00000026155
pleckstrin homology domain containing J1
chr3_+_175629374 0.10 ENSRNOT00000084027
ribosomal protein S21
chr5_-_78267063 0.10 ENSRNOT00000040894
ENSRNOT00000087648
cell division cycle 26
chr4_-_165192647 0.10 ENSRNOT00000086461
killer cell lectin-like receptor, subfamily A, member 5
chr1_-_198662610 0.09 ENSRNOT00000055012
septin 1
chr1_+_101517714 0.09 ENSRNOT00000028423
pleckstrin homology domain containing A4
chr15_+_12569235 0.09 ENSRNOT00000083787
THO complex 7
chr8_+_61615650 0.09 ENSRNOT00000007261
snurportin 1
chr5_-_136721379 0.09 ENSRNOT00000026704
ATPase H+ transporting V0 subunit B
chr2_+_69415057 0.09 ENSRNOT00000013152
cadherin 10
chr12_+_22259713 0.09 ENSRNOT00000001913
POP7 homolog, ribonuclease P/MRP subunit
chr8_+_116318963 0.09 ENSRNOT00000036556
tumor suppressor candidate 2
chr4_-_146839397 0.09 ENSRNOT00000010338
vestigial-like family member 4
chr8_+_5768811 0.09 ENSRNOT00000013936
matrix metallopeptidase 8
chr7_+_91384187 0.09 ENSRNOT00000005828
UTP23, small subunit processome component
chr1_+_198120099 0.09 ENSRNOT00000073652
bolA family member 2
chr2_+_260884337 0.09 ENSRNOT00000032808
crystallin zeta
chr2_+_52152536 0.09 ENSRNOT00000072691

chrX_+_78196300 0.09 ENSRNOT00000048695
purinergic receptor P2Y10
chr5_+_61425746 0.09 ENSRNOT00000064113
hypothetical LOC298077
chr13_-_61070599 0.09 ENSRNOT00000005251
regulator of G-protein signaling 1
chr9_-_9675110 0.09 ENSRNOT00000073294
vav guanine nucleotide exchange factor 1
chr5_+_126783061 0.09 ENSRNOT00000013224
transmembrane protein 59
chr6_+_101865917 0.09 ENSRNOT00000029888
family with sequence similarity 71, member D
chr4_-_44136815 0.09 ENSRNOT00000086810
transcription factor EC
chr13_-_90641772 0.09 ENSRNOT00000064601
ATPase Na+/K+ transporting subunit alpha 4
chr20_+_18547370 0.09 ENSRNOT00000000750
ubiquitin-conjugating enzyme E2D 1
chr14_-_23604834 0.09 ENSRNOT00000002760
signal transducing adaptor family member 1
chr1_+_197999336 0.09 ENSRNOT00000023555
apolipoprotein B receptor
chr7_+_145068286 0.09 ENSRNOT00000088956
ENSRNOT00000065753
NCK associated protein 1 like
chr3_+_28416954 0.09 ENSRNOT00000043533
kynureninase
chr6_+_28663602 0.08 ENSRNOT00000005402
peptidyl-tRNA hydrolase domain containing 1
chr2_-_27949066 0.08 ENSRNOT00000081472
ENSRNOT00000022138
NSA2 ribosome biogenesis homolog
chr11_-_54545230 0.08 ENSRNOT00000002676
resistin like alpha
chr1_-_77830399 0.08 ENSRNOT00000052231
ribosomal protein L9-like
chr3_+_28627084 0.08 ENSRNOT00000049884
Rho GTPase activating protein 15
chr8_+_61607015 0.08 ENSRNOT00000023456
IMP3, U3 small nucleolar ribonucleoprotein
chr5_+_169244778 0.08 ENSRNOT00000064841
pleckstrin homology and RhoGEF domain containing G5
chr2_-_250923744 0.08 ENSRNOT00000084996
chloride channel accessory 1
chr6_+_48021771 0.08 ENSRNOT00000060185
tumor suppressing subtransferable candidate 1
chr9_+_8052210 0.08 ENSRNOT00000073659
adhesion G protein-coupled receptor E4
chr1_-_98521706 0.08 ENSRNOT00000015941
sialic acid binding Ig-like lectin 10
chr4_-_164453171 0.08 ENSRNOT00000077539
ENSRNOT00000083610
ENSRNOT00000079975
Ly49 stimulatory receptor 6
chr4_+_163174487 0.08 ENSRNOT00000088108
C-type lectin domain family 9, member A
chr13_+_34267471 0.08 ENSRNOT00000061619
ENSRNOT00000092802
nucleolar protein interacting with the FHA domain of MKI67
chr2_+_28370373 0.08 ENSRNOT00000073183
ankyrin repeat family A protein 2-like
chr7_-_12646960 0.08 ENSRNOT00000014687
proteinase 3
chr10_-_109757550 0.08 ENSRNOT00000054957
Rho GDP dissociation inhibitor alpha
chr1_-_227506822 0.08 ENSRNOT00000091506
membrane spanning 4-domains A7
chr10_+_91126689 0.08 ENSRNOT00000004046
N-myristoyltransferase 1
chr7_-_1188165 0.08 ENSRNOT00000076063
ENSRNOT00000074108
ADP-ribosylation factor like GTPase 13B
chr1_-_103760913 0.08 ENSRNOT00000049722
MAS-related GPR, member X2
chr10_+_83655460 0.08 ENSRNOT00000008011
G protein subunit gamma transducin 2
chrX_+_72684329 0.08 ENSRNOT00000057644
DMRT-like family C1c1
chr4_-_164406146 0.08 ENSRNOT00000090110
killer cell lectin-like receptor subfamily A, member 22
chr11_-_66759402 0.08 ENSRNOT00000003326
hematopoietic cell specific Lyn substrate 1
chr12_-_38116919 0.08 ENSRNOT00000001467
density regulated reinitiation and release factor
chr13_-_89668473 0.07 ENSRNOT00000004938
ubiquitin-fold modifier conjugating enzyme 1
chrX_-_138237157 0.07 ENSRNOT00000003414
RAP2C, member of RAS oncogene family
chr1_-_254671778 0.07 ENSRNOT00000025493
5-hydroxytryptamine receptor 7
chr10_+_69412017 0.07 ENSRNOT00000009448
C-C motif chemokine ligand 2
chr16_-_84406538 0.07 ENSRNOT00000051980
LRRG00131
chr1_+_189550354 0.07 ENSRNOT00000083153
exonuclease NEF-sp
chr1_-_140535934 0.07 ENSRNOT00000065457
de-etiolated homolog 1 (Arabidopsis)
chr6_+_129519709 0.07 ENSRNOT00000006307
GSK3B interacting protein
chr6_-_102047758 0.07 ENSRNOT00000012101
ATPase H+ transporting V1 subunit D
chr2_-_197982385 0.07 ENSRNOT00000034074
mitochondrial ribosomal protein S21
chr6_-_94834908 0.07 ENSRNOT00000006284
trans-L-3-hydroxyproline dehydratase
chr5_+_163612518 0.07 ENSRNOT00000071103
60S ribosomal protein L9 pseudogene
chr1_-_98521551 0.07 ENSRNOT00000081922
sialic acid binding Ig-like lectin 10
chr1_-_157461588 0.07 ENSRNOT00000068402
ankyrin repeat domain 42
chr6_-_103470427 0.07 ENSRNOT00000091560
ENSRNOT00000088795
ENSRNOT00000079824
actinin, alpha 1
chr18_+_29386809 0.07 ENSRNOT00000082079
ENSRNOT00000024825
eukaryotic translation initiation factor 4E binding protein 3
chr1_+_189549960 0.07 ENSRNOT00000019654
exonuclease NEF-sp
chr10_+_109630099 0.07 ENSRNOT00000072099
coiled-coil domain containing 137
chr9_-_65329066 0.07 ENSRNOT00000018284
peptidylprolyl isomerase like 3
chr10_+_55013703 0.07 ENSRNOT00000032785
phosphoinositide-3-kinase, regulatory subunit 5
chr10_+_85978691 0.07 ENSRNOT00000006359
ribosomal protein L19
chr18_+_35574002 0.07 ENSRNOT00000093442
ENSRNOT00000070817
ENSRNOT00000093356
myotilin
chr3_-_63535991 0.07 ENSRNOT00000015722
FK506 binding protein 7
chr1_+_88620317 0.07 ENSRNOT00000075116
cytochrome c oxidase subunit 7A1
chr4_-_165026414 0.07 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr9_+_37727942 0.07 ENSRNOT00000016511
ENSRNOT00000074276
myotilin-like
chr20_+_6869767 0.07 ENSRNOT00000000631
ENSRNOT00000086330
ENSRNOT00000093188
ENSRNOT00000093736
similar to GI:13385412-like protein splice form I
chr4_-_157252565 0.07 ENSRNOT00000079947
protein tyrosine phosphatase, non-receptor type 6
chr5_-_155916893 0.07 ENSRNOT00000055947
low density lipoprotein receptor class A domain containing 2
chr13_+_110007010 0.07 ENSRNOT00000005387
transmembrane protein 206
chr7_+_135803698 0.07 ENSRNOT00000007932
interleukin-1 receptor-associated kinase 4
chr1_-_198652674 0.07 ENSRNOT00000023706
TBC1 domain family, member 10b
chr9_+_94745217 0.06 ENSRNOT00000051338
inositol polyphosphate-5-phosphatase D
chr3_+_159995064 0.06 ENSRNOT00000012606
alpha tocopherol transfer protein like
chr1_-_91074294 0.06 ENSRNOT00000075236
similar to Cytochrome c oxidase polypeptide VIIa-heart, mitochondrial precursor (Cytochrome c oxidase subunit VIIa-H) (COX VIIa-M)
chr6_-_111132320 0.06 ENSRNOT00000016057
neuroglobin
chr17_+_9797907 0.06 ENSRNOT00000021638
lectin, mannose-binding 2
chr10_+_65805860 0.06 ENSRNOT00000011795
intraflagellar transport 20
chr11_-_14304603 0.06 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr1_+_60717386 0.06 ENSRNOT00000015019
protein phosphatase 2 scaffold subunit A alpha
chr1_+_255479261 0.06 ENSRNOT00000079808
tankyrase 2
chrX_-_77700269 0.06 ENSRNOT00000092418
cysteinyl leukotriene receptor 1
chr4_+_78320190 0.06 ENSRNOT00000032742
ENSRNOT00000091359
GTPase, IMAP family member 4
chr8_-_68525911 0.06 ENSRNOT00000080588
ENSRNOT00000011109
IQ motif containing H
chr4_-_164900857 0.06 ENSRNOT00000078690
Ly49 inhibitory receptor 2
chr13_-_90832469 0.06 ENSRNOT00000086508
immunoglobulin superfamily, member 9
chr14_+_81043454 0.06 ENSRNOT00000043609

chr10_+_75087892 0.06 ENSRNOT00000065910
myeloperoxidase
chr11_+_27210593 0.06 ENSRNOT00000084580
MAP3K7 C-terminal like
chr12_+_25497104 0.06 ENSRNOT00000002028
neutrophil cytosolic factor 1
chrX_+_17171605 0.06 ENSRNOT00000048236
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr16_+_6970342 0.06 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr3_+_112228720 0.06 ENSRNOT00000079079
calpain 3
chr5_-_135472116 0.06 ENSRNOT00000022170
nuclear autoantigenic sperm protein
chr4_-_157433467 0.06 ENSRNOT00000028965
lymphocyte activating 3
chr3_-_46726946 0.06 ENSRNOT00000011030
ENSRNOT00000086576
integrin subunit beta 6
chrX_-_82418425 0.06 ENSRNOT00000022525
ankyrin repeat family A member 2
chr1_+_21525421 0.06 ENSRNOT00000017911
arginase 1
chr4_+_21862313 0.06 ENSRNOT00000007948
cyclin D binding myb-like transcription factor 1
chr20_+_3344870 0.06 ENSRNOT00000001058
ENSRNOT00000087613
ENSRNOT00000089978
mitochondrial ribosomal protein S18B
chr1_-_36112993 0.06 ENSRNOT00000023161
mediator complex subunit 10
chr9_+_24066303 0.05 ENSRNOT00000018163
cysteine-rich secretory protein 3
chr4_+_6946634 0.05 ENSRNOT00000040373
WD repeat domain 86
chrX_+_20351486 0.05 ENSRNOT00000093675
ENSRNOT00000047444
WNK lysine deficient protein kinase 3
chr5_-_171459488 0.05 ENSRNOT00000075423
ENSRNOT00000080686
tumor protein p63 regulated 1-like
chr9_+_65614142 0.05 ENSRNOT00000016613
caspase 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Spic

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.1 0.3 GO:0035359 negative regulation of histone phosphorylation(GO:0033128) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:0002434 immune complex clearance(GO:0002434)
0.1 0.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 0.2 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.1 0.3 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:1904845 regulation of renal output by angiotensin(GO:0002019) response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.3 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0046864 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.0 0.1 GO:1903969 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.0 0.1 GO:1904117 cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:2000688 positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:1900673 olefin metabolic process(GO:1900673)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:1902560 GMP reductase complex(GO:1902560)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0051425 inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.0 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.0 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism