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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Spi1

Z-value: 1.12

Motif logo

Transcription factors associated with Spi1

Gene Symbol Gene ID Gene Info
ENSRNOG00000012172 Spi-1 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spi1rn6_v1_chr3_+_79918969_799189690.672.1e-01Click!

Activity profile of Spi1 motif

Sorted Z-values of Spi1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_43117337 0.47 ENSRNOT00000078001
nuclear receptor subfamily 4, group A, member 2
chr8_+_96551245 0.41 ENSRNOT00000039850
BCL2-related protein A1
chr12_-_19254527 0.40 ENSRNOT00000089349

chr9_-_14599594 0.40 ENSRNOT00000018138
triggering receptor expressed on myeloid cells-like 1
chr19_-_55510460 0.40 ENSRNOT00000019820
CBFA2/RUNX1 translocation partner 3
chr7_+_119820537 0.38 ENSRNOT00000077256
ENSRNOT00000056221
cytohesin 4
chr10_-_83655182 0.35 ENSRNOT00000007897
ABI family, member 3
chr7_-_140245723 0.34 ENSRNOT00000088999
cyclin T1
chr4_-_169999873 0.34 ENSRNOT00000011697
glutamate ionotropic receptor NMDA type subunit 2B
chr2_-_243224883 0.33 ENSRNOT00000014139
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr7_+_20262680 0.33 ENSRNOT00000046378
similar to hypothetical protein 4930509O22
chr1_-_226887156 0.32 ENSRNOT00000054809
ENSRNOT00000028347
Cd6 molecule
chr10_-_61361250 0.32 ENSRNOT00000092203
RAP1 GTPase activating protein 2
chr10_-_70802782 0.32 ENSRNOT00000045867
chemokine (C-C motif) ligand 6
chr11_-_60882379 0.32 ENSRNOT00000002799
CD200 receptor 1
chr8_+_29453643 0.31 ENSRNOT00000090643
opioid binding protein/cell adhesion molecule-like
chr7_-_36408588 0.31 ENSRNOT00000063946
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_25174456 0.31 ENSRNOT00000092830
clavesin 2
chr7_+_145068286 0.30 ENSRNOT00000088956
ENSRNOT00000065753
NCK associated protein 1 like
chr6_+_112203679 0.30 ENSRNOT00000031205
neurexin 3
chr20_-_5485837 0.30 ENSRNOT00000092272
ENSRNOT00000000559
ENSRNOT00000092597
death-domain associated protein
chr1_-_199439210 0.30 ENSRNOT00000026699
PYD and CARD domain containing
chr5_-_79570073 0.30 ENSRNOT00000011845
tumor necrosis factor superfamily member 15
chr6_-_1319541 0.29 ENSRNOT00000006527
striatin
chr2_+_251200686 0.29 ENSRNOT00000019210
collagen type XXIV alpha 1 chain
chr4_-_113866674 0.29 ENSRNOT00000010020
docking protein 1
chr20_+_5535432 0.29 ENSRNOT00000040859
synaptic Ras GTPase activating protein 1
chr10_+_83655460 0.29 ENSRNOT00000008011
G protein subunit gamma transducin 2
chr9_-_13877130 0.29 ENSRNOT00000015705
leucine rich repeat and fibronectin type III domain containing 2
chr3_-_72602548 0.27 ENSRNOT00000031745
leucine rich repeat containing 55
chr18_-_1389929 0.27 ENSRNOT00000051362
Rho-associated coiled-coil containing protein kinase 1
chr15_-_42947656 0.27 ENSRNOT00000030007
protein tyrosine kinase 2 beta
chr4_+_150133590 0.27 ENSRNOT00000051804
RasGEF domain family, member 1A
chr20_+_5646097 0.27 ENSRNOT00000090925
inositol 1,4,5-trisphosphate receptor, type 3
chr10_+_11912543 0.26 ENSRNOT00000045192
zinc finger protein 597
chr7_-_93826665 0.26 ENSRNOT00000011344
TNF receptor superfamily member 11B
chr1_-_260254600 0.26 ENSRNOT00000019014
B-cell linker
chr6_-_108796124 0.26 ENSRNOT00000086545
apoptosis resistant E3 ubiquitin protein ligase 1
chr18_-_1390190 0.26 ENSRNOT00000061777
Rho-associated coiled-coil containing protein kinase 1
chr10_-_64657089 0.25 ENSRNOT00000080703
active BCR-related
chr10_-_85084850 0.25 ENSRNOT00000012462
TBK1 binding protein 1
chr5_-_79222687 0.25 ENSRNOT00000010516
AT-hook transcription factor
chr4_+_157513414 0.25 ENSRNOT00000078769
PILR alpha associated neural protein
chr4_+_157524423 0.25 ENSRNOT00000036654
zinc finger protein 384
chr9_-_52238564 0.25 ENSRNOT00000005073
collagen type V alpha 2 chain
chr1_+_220428481 0.24 ENSRNOT00000027335
ras and Rab interactor 1
chr7_-_52404774 0.24 ENSRNOT00000082100
neuron navigator 3
chr17_-_85141210 0.24 ENSRNOT00000000162
DnaJ heat shock protein family (Hsp40) member C1
chr20_+_4355175 0.24 ENSRNOT00000000510
G-protein signaling modulator 3
chr10_+_34383396 0.24 ENSRNOT00000047186
olfactory receptor 1386
chr1_+_255801694 0.24 ENSRNOT00000018878

chr2_-_265300868 0.24 ENSRNOT00000066024
ENSRNOT00000016073
ENSRNOT00000033502
leucine rich repeat containing 7
chr5_+_169288871 0.24 ENSRNOT00000055466
TNF receptor superfamily member 25
chr1_-_227047290 0.23 ENSRNOT00000037226
membrane spanning 4-domains A15
chr9_+_99795678 0.23 ENSRNOT00000056601
olfactory receptor 1353
chr9_+_66568074 0.23 ENSRNOT00000035238
bone morphogenetic protein receptor type 2
chr11_+_84745904 0.23 ENSRNOT00000002617
kelch-like family member 6
chr6_+_106052212 0.23 ENSRNOT00000010626
signal-induced proliferation-associated 1 like 1
chr3_-_6626284 0.23 ENSRNOT00000012494
ficolin B
chr6_+_86713803 0.23 ENSRNOT00000005861
family with sequence similarity 179, member B
chr3_+_58965552 0.23 ENSRNOT00000002068
mitogen-activated protein kinase kinase kinase 20
chr12_+_38144855 0.23 ENSRNOT00000032274
hydroxycarboxylic acid receptor 1
chr2_+_210045161 0.23 ENSRNOT00000024455
solute carrier family 16, member 4
chr5_-_169630340 0.23 ENSRNOT00000087043
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chrX_-_115175299 0.23 ENSRNOT00000074322
doublecortin
chr2_-_13696426 0.22 ENSRNOT00000046251
RAS p21 protein activator 1
chr13_-_100740728 0.22 ENSRNOT00000000074
F-box protein 28
chr11_+_61531416 0.22 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr14_+_39661968 0.22 ENSRNOT00000064779
gamma-aminobutyric acid type A receptor alpha2 subunit
chr13_-_88943592 0.22 ENSRNOT00000032218
hypothetical LOC100361087
chr3_+_122114108 0.22 ENSRNOT00000091935
signal-regulatory protein alpha
chr17_+_43357888 0.22 ENSRNOT00000022329
secretagogin, EF-hand calcium binding protein
chr1_-_65681440 0.22 ENSRNOT00000026305
zinc finger protein 128
chr7_+_143707237 0.22 ENSRNOT00000074212
tensin 2
chr9_-_30844199 0.21 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr4_+_175729726 0.21 ENSRNOT00000013230
solute carrier organic anion transporter family, member 1c1
chr2_+_189062443 0.21 ENSRNOT00000028181
adenosine deaminase, RNA-specific
chr5_-_147635789 0.21 ENSRNOT00000037106
zinc finger and BTB domain containing 8b
chr1_-_80221710 0.21 ENSRNOT00000091687
FosB proto-oncogene, AP-1 transcription factor subunit
chr17_+_43734461 0.21 ENSRNOT00000072564
histone cluster 1, H1d
chr7_+_132857628 0.21 ENSRNOT00000005438
leucine-rich repeat kinase 2
chr7_-_144936803 0.21 ENSRNOT00000055279
G protein-coupled receptor 84
chr3_-_111037425 0.21 ENSRNOT00000085628
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr2_-_188553289 0.21 ENSRNOT00000088822
tripartite motif-containing 46
chr3_+_79918969 0.21 ENSRNOT00000016306
Spi-1 proto-oncogene
chr20_+_28572242 0.21 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr1_+_79790705 0.21 ENSRNOT00000018233
peptidoglycan recognition protein 1
chr10_-_103685844 0.20 ENSRNOT00000064284
Cd300 molecule-like family member F
chr7_+_2795901 0.20 ENSRNOT00000047462
ankyrin repeat domain 52
chr2_+_208373154 0.20 ENSRNOT00000082943
ENSRNOT00000050538
adenosine receptor A3-like
chr9_+_94745217 0.20 ENSRNOT00000051338
inositol polyphosphate-5-phosphatase D
chr1_-_198120061 0.20 ENSRNOT00000026231
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr16_-_47874856 0.20 ENSRNOT00000077810
RWD domain containing 4
chr7_+_23403891 0.20 ENSRNOT00000037918
synapsin III
chr3_+_104899682 0.20 ENSRNOT00000041910
formin 1
chr5_-_119564846 0.20 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chr18_-_29611212 0.20 ENSRNOT00000022685
DND microRNA-mediated repression inhibitor 1
chr15_+_60084918 0.20 ENSRNOT00000012632
epithelial stromal interaction 1
chr1_-_198662610 0.20 ENSRNOT00000055012
septin 1
chr5_+_82587420 0.19 ENSRNOT00000014020
toll-like receptor 4
chr3_+_100769839 0.19 ENSRNOT00000077703
brain-derived neurotrophic factor
chr2_-_140618405 0.19 ENSRNOT00000017736
SET domain containing (lysine methyltransferase) 7
chr4_+_66090209 0.19 ENSRNOT00000031193
tetratricopeptide repeat domain 26
chr17_-_67945037 0.19 ENSRNOT00000023033
Kruppel-like factor 6
chr10_+_64737022 0.19 ENSRNOT00000017071
ENSRNOT00000093232
ENSRNOT00000017042
ENSRNOT00000093244
galectin 9
chr3_-_39596718 0.19 ENSRNOT00000006784
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_+_39960542 0.19 ENSRNOT00000013370
Myb/SANT-like DNA-binding domain containing 2
chr2_+_181331464 0.19 ENSRNOT00000017448
microtubule-associated protein 9
chr4_-_95970666 0.19 ENSRNOT00000008826
hematopoietic prostaglandin D synthase
chr10_-_70788309 0.19 ENSRNOT00000029184
chemokine (C-C motif) ligand 9
chrX_-_26376467 0.19 ENSRNOT00000051655
ENSRNOT00000036502
Rho GTPase activating protein 6
chr2_-_208225888 0.19 ENSRNOT00000054860

chr3_-_177205836 0.19 ENSRNOT00000034209
LKAAEAR motif containing 1
chr17_+_22620721 0.18 ENSRNOT00000019478
androgen-dependent TFPI-regulating protein
chr4_+_32373641 0.18 ENSRNOT00000076086
distal-less homeobox 6
chr18_-_73873280 0.18 ENSRNOT00000075580
ring finger protein 165
chr12_-_47482961 0.18 ENSRNOT00000001600
2'-5' oligoadenylate synthetase-like 2
chr1_-_157461588 0.18 ENSRNOT00000068402
ankyrin repeat domain 42
chr10_+_18996523 0.18 ENSRNOT00000046135
lymphocyte cytosolic protein 2
chr19_+_10519493 0.18 ENSRNOT00000030229
coiled-coil domain containing 102A
chr6_+_106496992 0.18 ENSRNOT00000086136
ENSRNOT00000058181
regulator of G-protein signaling 6
chr13_-_55173692 0.18 ENSRNOT00000064785
ENSRNOT00000029878
ENSRNOT00000029865
ENSRNOT00000060292
ENSRNOT00000000814
protein tyrosine phosphatase, receptor type, C
chr11_+_82848853 0.18 ENSRNOT00000073743
thrombopoietin
chrX_+_1311121 0.18 ENSRNOT00000038909
complement factor properdin
chr1_+_224882439 0.18 ENSRNOT00000024785
cholinergic receptor, muscarinic 1
chr16_-_47874647 0.18 ENSRNOT00000035323
RWD domain containing 4
chr8_-_14880644 0.17 ENSRNOT00000015977
FAT atypical cadherin 3
chr6_+_64252970 0.17 ENSRNOT00000093700
patatin-like phospholipase domain containing 8
chr17_+_9639330 0.17 ENSRNOT00000018232
docking protein 3
chr18_-_56115593 0.17 ENSRNOT00000045041
treacle ribosome biogenesis factor 1
chr6_-_76552559 0.17 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr7_-_90318221 0.17 ENSRNOT00000050774
transcriptional repressor GATA binding 1
chrX_+_22302703 0.17 ENSRNOT00000078617
ENSRNOT00000086952
lysine demethylase 5C
chrX_-_68563137 0.17 ENSRNOT00000034772
oligophrenin 1
chr1_-_72461547 0.17 ENSRNOT00000022480
scavenger receptor cysteine rich family member with 5 domains
chr17_-_78812111 0.17 ENSRNOT00000021506
DNA cross-link repair 1C
chrX_-_68562873 0.17 ENSRNOT00000076193
oligophrenin 1
chr3_+_110723481 0.17 ENSRNOT00000013878
bromo adjacent homology domain containing 1
chr13_-_50916982 0.17 ENSRNOT00000004408
BTG anti-proliferation factor 2
chrX_+_68891227 0.17 ENSRNOT00000009635
ephrin B1
chr4_+_157523770 0.17 ENSRNOT00000055985
ENSRNOT00000023240
zinc finger protein 384
chr5_-_137321121 0.17 ENSRNOT00000027414
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr10_+_77537340 0.17 ENSRNOT00000003297
transmembrane protein 100
chr2_-_185303610 0.17 ENSRNOT00000093479
ENSRNOT00000046286
protease, serine 48
chr17_+_88215834 0.17 ENSRNOT00000034098
G protein-coupled receptor 158
chr3_-_60795951 0.17 ENSRNOT00000002174
activating transcription factor 2
chr18_-_786674 0.17 ENSRNOT00000021955
centrin 1
chr7_-_142300382 0.17 ENSRNOT00000048262
bridging integrator 2
chr2_-_21698937 0.17 ENSRNOT00000080165

chr8_+_107882219 0.17 ENSRNOT00000019902
DAZ interacting zinc finger protein 1-like
chr10_+_57660067 0.17 ENSRNOT00000010144
MIS12 kinetochore complex component
chr17_-_21739408 0.16 ENSRNOT00000060335
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr3_+_148773259 0.16 ENSRNOT00000013804
kinesin family member 3B
chr7_-_122403667 0.16 ENSRNOT00000088814
megakaryoblastic leukemia (translocation) 1
chr2_+_234375315 0.16 ENSRNOT00000071270
elongation of very long chain fatty acids protein 6-like
chr7_+_18440742 0.16 ENSRNOT00000011513
myosin IF
chr6_-_76652757 0.16 ENSRNOT00000042177
ferritin light chain 2
chrX_+_82143789 0.16 ENSRNOT00000003724
POU class 3 homeobox 4
chr8_-_133002201 0.16 ENSRNOT00000008772
C-C motif chemokine receptor 1
chr15_-_42898150 0.16 ENSRNOT00000030036
protein tyrosine kinase 2 beta
chr2_+_11658568 0.16 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chr20_+_44060731 0.16 ENSRNOT00000000737
laminin subunit alpha 4
chrX_+_134979646 0.16 ENSRNOT00000006035
SAM and SH3 domain containing 3
chr16_-_2227258 0.16 ENSRNOT00000089377
ENSRNOT00000067464
sarcolemma associated protein
chr13_+_89774764 0.16 ENSRNOT00000005619
Rho GTPase activating protein 30
chr4_-_27473150 0.16 ENSRNOT00000032505
KRIT1, ankyrin repeat containing
chr18_+_24849545 0.16 ENSRNOT00000061011
ENSRNOT00000085516
IWS1, SUPT6H interacting protein
chr12_-_47987255 0.16 ENSRNOT00000074000
ubiquitin protein ligase E3B
chr2_+_118746333 0.16 ENSRNOT00000079431

chr12_+_7081895 0.16 ENSRNOT00000047163
high mobility group box 1
chr1_-_78521999 0.16 ENSRNOT00000021223
Rho GTPase activating protein 35
chr20_-_5865775 0.15 ENSRNOT00000000612
ENSRNOT00000092641
SRSF protein kinase 1
chr2_-_190100276 0.15 ENSRNOT00000015351
S100 calcium binding protein A9
chr1_+_276309927 0.15 ENSRNOT00000067460
ENSRNOT00000066236
vesicle transport through interaction with t-SNAREs 1A
chr1_+_91857057 0.15 ENSRNOT00000077993
ENSRNOT00000081465
ankyrin repeat domain 27
chr15_-_45927804 0.15 ENSRNOT00000086271
integrator complex subunit 6
chr5_+_156613741 0.15 ENSRNOT00000076031
SH2 domain containing 5
chr18_-_55916220 0.15 ENSRNOT00000025934
synaptopodin
chr7_-_104801045 0.15 ENSRNOT00000079524
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr9_+_82718709 0.15 ENSRNOT00000027256
ENSRNOT00000080524
serine/threonine kinase 11 interacting protein
chr5_-_136715981 0.15 ENSRNOT00000026591
beta-1,4-galactosyltransferase 2
chr14_+_33624390 0.15 ENSRNOT00000002907
aminoadipate-semialdehyde dehydrogenase
chr7_-_119797098 0.15 ENSRNOT00000009994
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chrX_+_45637415 0.15 ENSRNOT00000050544
similar to ferritin heavy polypeptide-like 17
chr17_-_9791781 0.15 ENSRNOT00000090536
regulator of G-protein signaling 14
chr3_+_71114100 0.15 ENSRNOT00000088549
ENSRNOT00000006961
integrin subunit alpha V
chr3_+_110982553 0.15 ENSRNOT00000030754
hypothetical protein LOC691418
chr10_+_91254058 0.15 ENSRNOT00000087218
ENSRNOT00000065373
formin-like 1
chr3_+_15560712 0.15 ENSRNOT00000010218
prostaglandin-endoperoxide synthase 1
chr3_-_937102 0.15 ENSRNOT00000007471
histamine N-methyltransferase
chr17_+_22619891 0.15 ENSRNOT00000060403
androgen-dependent TFPI-regulating protein
chr2_-_138833933 0.15 ENSRNOT00000013343
protocadherin 18
chr8_-_33661049 0.15 ENSRNOT00000068037
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_199682688 0.15 ENSRNOT00000027265
ENSRNOT00000080872
solute carrier family 5 member 2
chr3_-_123849788 0.15 ENSRNOT00000028869
ring finger protein 24
chr1_+_88078350 0.15 ENSRNOT00000048677
RAS guanyl releasing protein 4
chr14_+_84150908 0.15 ENSRNOT00000005516
dual specificity phosphatase 18
chr6_+_86713604 0.15 ENSRNOT00000059271
family with sequence similarity 179, member B
chr2_+_242634399 0.15 ENSRNOT00000035700
endomucin
chr13_+_48790767 0.15 ENSRNOT00000087504
ELK4, ETS transcription factor

Network of associatons between targets according to the STRING database.

First level regulatory network of Spi1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 0.5 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.4 GO:2000426 negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.9 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.1 0.3 GO:0071454 cellular response to anoxia(GO:0071454)
0.1 0.3 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.3 GO:0010070 zygote asymmetric cell division(GO:0010070)
0.1 0.5 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.1 0.3 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.1 0.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.2 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.1 0.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.2 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499) regulation of peroxidase activity(GO:2000468)
0.1 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.6 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 0.2 GO:1990268 detection of lipopolysaccharide(GO:0032497) response to gold nanoparticle(GO:1990268)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.2 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.1 GO:0072199 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.1 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) regulation of cellular response to drug(GO:2001038)
0.0 0.2 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0003284 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.0 0.2 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.0 0.1 GO:1905204 negative regulation of connective tissue replacement(GO:1905204)
0.0 0.1 GO:0072125 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:1905072 cardiac jelly development(GO:1905072)
0.0 0.3 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.5 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0060939 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0072262 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0060066 oviduct development(GO:0060066)
0.0 0.3 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.1 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.3 GO:0061193 taste bud development(GO:0061193)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0006863 purine nucleobase transport(GO:0006863) nucleobase transport(GO:0015851)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:2001295 multicellular organismal protein metabolic process(GO:0044268) malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
0.0 0.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:0032304 gastrin-induced gastric acid secretion(GO:0001698) negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.1 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.1 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.0 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.3 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.3 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0090309 DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:1903544 response to butyrate(GO:1903544)
0.0 0.0 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.7 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.0 0.0 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.0 0.0 GO:0072191 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 0.1 GO:0036395 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.0 GO:1905075 ossification involved in bone remodeling(GO:0043932) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.0 GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.0 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.0 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0032484 Ral protein signal transduction(GO:0032484)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0002467 germinal center formation(GO:0002467)
0.0 0.0 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113)
0.0 0.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.0 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0019323 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.0 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.0 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.0 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.0 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962) rRNA import into mitochondrion(GO:0035928)
0.0 0.4 GO:0090662 ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.0 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.6 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.0 GO:0098830 presynaptic endosome(GO:0098830)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0036396 MIS complex(GO:0036396)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0070110 interleukin-6 receptor complex(GO:0005896) ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0000938 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.0 GO:1990879 CST complex(GO:1990879)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.0 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.0 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.0 GO:0045025 mitochondrial degradosome(GO:0045025)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.2 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.2 GO:0071791 chemokine (C-C motif) ligand 5 binding(GO:0071791)
0.1 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0032142 single guanine insertion binding(GO:0032142)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635) calcitonin receptor activity(GO:0004948)
0.0 0.0 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.0 4.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503) benzaldehyde dehydrogenase activity(GO:0019115) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.0 GO:0017002 activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.0 GO:0035375 zymogen binding(GO:0035375)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation