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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Sp2

Z-value: 0.38

Motif logo

Transcription factors associated with Sp2

Gene Symbol Gene ID Gene Info
ENSRNOG00000010492 Sp2 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sp2rn6_v1_chr10_-_84915471_84915471-0.701.9e-01Click!

Activity profile of Sp2 motif

Sorted Z-values of Sp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_22937916 0.10 ENSRNOT00000088255
ENSRNOT00000049993
coiled-coil domain containing 159
chr17_-_67904674 0.10 ENSRNOT00000078532
Kruppel-like factor 6
chrX_-_134866210 0.08 ENSRNOT00000005331
apelin
chr1_-_226501920 0.08 ENSRNOT00000050716
leucine rich repeat containing 10B
chr1_-_222182721 0.08 ENSRNOT00000078008
testis expressed 40
chr6_-_55647665 0.07 ENSRNOT00000007414
basic leucine zipper and W2 domains 2
chr10_+_109107389 0.07 ENSRNOT00000068437
ENSRNOT00000005687
BAI1-associated protein 2
chr1_-_80073223 0.07 ENSRNOT00000021456
gastric inhibitory polypeptide receptor
chr7_+_41114697 0.07 ENSRNOT00000041354
ATPase plasma membrane Ca2+ transporting 1
chr19_-_38321528 0.07 ENSRNOT00000031977
sphingomyelin phosphodiesterase 3
chr7_+_53878610 0.06 ENSRNOT00000091910
oxysterol binding protein-like 8
chr1_-_198120061 0.06 ENSRNOT00000026231
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr20_+_4967194 0.06 ENSRNOT00000070846
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_1319541 0.06 ENSRNOT00000006527
striatin
chr10_+_56445647 0.05 ENSRNOT00000056870
transmembrane protein 256
chr18_-_6587080 0.05 ENSRNOT00000040815
60S ribosomal protein L39
chr6_+_137184820 0.05 ENSRNOT00000073796
adenylosuccinate synthase like 1
chr1_+_101405314 0.05 ENSRNOT00000028194
neurotrophin 4
chr3_+_51883559 0.05 ENSRNOT00000007197
cysteine and serine rich nuclear protein 3
chr5_-_136112344 0.05 ENSRNOT00000050195
RGD1563714
chr3_+_134413170 0.05 ENSRNOT00000074338

chr17_+_6701315 0.05 ENSRNOT00000026054
ENSRNOT00000080683
kinesin family member 27
chr1_+_221710670 0.05 ENSRNOT00000064798
mitogen activated protein kinase kinase kinase kinase 2
chr4_-_177331874 0.04 ENSRNOT00000065387
ENSRNOT00000091099
C2 calcium-dependent domain containing 5
chrX_+_157150655 0.04 ENSRNOT00000090795
pregnancy up-regulated nonubiquitous CaM kinase
chrX_-_78911601 0.04 ENSRNOT00000003188
similar to RIKEN cDNA 2610002M06
chrX_-_123254557 0.04 ENSRNOT00000039809
A kinase (PRKA) anchor protein 17B
chr12_+_22259713 0.04 ENSRNOT00000001913
POP7 homolog, ribonuclease P/MRP subunit
chr1_-_199377035 0.04 ENSRNOT00000026572
protease, serine, 8
chr16_+_3051449 0.04 ENSRNOT00000074069
family with sequence similarity 208, member A
chr10_+_29289203 0.04 ENSRNOT00000067013
PWWP domain containing 2A
chr5_-_85123829 0.04 ENSRNOT00000007578
BMP/retinoic acid inducible neural specific 1
chr3_-_110828879 0.04 ENSRNOT00000013963
coiled-coil domain containing 32
chr10_-_8498422 0.04 ENSRNOT00000082332
RNA binding protein, fox-1 homolog 1
chr4_-_180887050 0.04 ENSRNOT00000065730
integrator complex subunit 13
chr5_+_57947716 0.04 ENSRNOT00000067657
dynein, axonemal, intermediate chain 1
chr5_+_106409456 0.04 ENSRNOT00000058387
focadhesin
chr13_+_52976507 0.04 ENSRNOT00000090599
ENSRNOT00000011324
kinesin family member 21B
chr8_-_22937909 0.03 ENSRNOT00000015684
transmembrane protein 205
chr3_-_163935617 0.03 ENSRNOT00000074023
potassium voltage-gated channel subfamily B member 1
chrX_-_152641679 0.03 ENSRNOT00000080277
gamma-aminobutyric acid type A receptor alpha3 subunit
chr7_+_26375866 0.03 ENSRNOT00000059639
aldehyde dehydrogenase 1 family, member L2
chrX_+_20484517 0.03 ENSRNOT00000093701
family with sequence similarity 120C
chr6_+_24064738 0.03 ENSRNOT00000035362
yippee-like 5
chr11_-_83867203 0.03 ENSRNOT00000002394
chordin
chr9_+_112293388 0.03 ENSRNOT00000020767
mannosidase, alpha, class 2A, member 1
chr7_+_94130852 0.03 ENSRNOT00000011485
mal, T-cell differentiation protein 2
chr4_-_58195143 0.03 ENSRNOT00000033706
coatomer protein complex, subunit gamma 2
chr7_+_140315368 0.03 ENSRNOT00000081206
calcium voltage-gated channel auxiliary subunit beta 3
chr2_+_209097927 0.03 ENSRNOT00000023807
DENN domain containing 2D
chr1_-_221420115 0.03 ENSRNOT00000028475
mitochondrial ribosomal protein L49
chr5_+_122647281 0.03 ENSRNOT00000066041
mesoderm induction early response 1, transcriptional regulator
chr17_-_55709740 0.03 ENSRNOT00000033359
similar to OTTHUMP00000046255
chr10_+_56591292 0.03 ENSRNOT00000023379
CTD nuclear envelope phosphatase 1
chr13_-_78608844 0.03 ENSRNOT00000003671
RAB GTPase activating protein 1-like
chrX_-_10630281 0.03 ENSRNOT00000080651
ENSRNOT00000048980
ubiquitin specific peptidase 9, X-linked
chr19_+_38846201 0.03 ENSRNOT00000030768
ENSRNOT00000063977
transport and golgi organization 6 homolog
chr1_+_126523169 0.03 ENSRNOT00000051000
threonyl-tRNA synthetase-like 2
chr10_-_54467956 0.03 ENSRNOT00000065383
ubiquitin specific peptidase 43
chr1_-_198232344 0.03 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr6_-_103470427 0.03 ENSRNOT00000091560
ENSRNOT00000088795
ENSRNOT00000079824
actinin, alpha 1
chr7_-_143863186 0.03 ENSRNOT00000017096
retinoic acid receptor, gamma
chr5_+_173340060 0.03 ENSRNOT00000067841
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr6_-_55001464 0.03 ENSRNOT00000006618
aryl hydrocarbon receptor
chrX_-_154722220 0.03 ENSRNOT00000089743
ENSRNOT00000087893
fragile X mental retardation 1
chr10_+_28243 0.03 ENSRNOT00000003193
ENSRNOT00000087156
meiosis arrest female protein 1-like
chr1_+_165625058 0.03 ENSRNOT00000025104
RAB6A, member RAS oncogene family
chr1_-_263718745 0.03 ENSRNOT00000074810
dynamin binding protein
chr4_+_180887182 0.03 ENSRNOT00000042270
ENSRNOT00000002476
FGFR1 oncogene partner 2
chr4_+_60549197 0.03 ENSRNOT00000071249
ENSRNOT00000075621
exocyst complex component 4
chr5_+_135574172 0.03 ENSRNOT00000023416
testis-specific kinase 2
chr12_-_38274036 0.03 ENSRNOT00000063990
kinetochore associated 1
chr3_-_3890758 0.03 ENSRNOT00000064083
SEC16 homolog A, endoplasmic reticulum export factor
chr15_-_43733182 0.03 ENSRNOT00000015318
protein phosphatase 2, regulatory subunit B, alpha
chr9_+_81783349 0.03 ENSRNOT00000021548
CCR4-NOT transcription complex subunit 9
chr5_-_150390099 0.02 ENSRNOT00000014479
YTH N(6)-methyladenosine RNA binding protein 2
chr5_+_172986291 0.02 ENSRNOT00000022900
NAD kinase
chr2_+_211050360 0.02 ENSRNOT00000026928
proteasome subunit alpha 5
chr5_-_147375009 0.02 ENSRNOT00000009436
S100P binding protein
chr6_+_26686033 0.02 ENSRNOT00000081167
solute carrier family 5 member 6
chr3_+_33641616 0.02 ENSRNOT00000051953
enhancer of polycomb homolog 2
chr18_+_72550219 0.02 ENSRNOT00000046847
SMAD family member 2
chr13_-_35048444 0.02 ENSRNOT00000009963
GLI family zinc finger 2
chrX_-_22413714 0.02 ENSRNOT00000084129
ENSRNOT00000085905
TSPY-like 2
chr20_+_5535432 0.02 ENSRNOT00000040859
synaptic Ras GTPase activating protein 1
chr5_+_9279970 0.02 ENSRNOT00000067977
myeloblastosis oncogene-like 1
chr20_-_11528332 0.02 ENSRNOT00000038419
thrombospondin-type laminin G domain and EAR repeats
chr20_-_29199224 0.02 ENSRNOT00000071477
mitochondrial calcium uniporter
chr13_-_86671515 0.02 ENSRNOT00000082869

chr1_+_162549420 0.02 ENSRNOT00000037050
remodeling and spacing factor 1
chr1_+_80195532 0.02 ENSRNOT00000022528
reticulon 2
chr2_-_210991509 0.02 ENSRNOT00000087329
cytochrome b561 family, member D1
chr1_+_238843338 0.02 ENSRNOT00000024583
zinc finger AN1-type containing 5
chr6_-_26685235 0.02 ENSRNOT00000066743
all-trans retinoic acid-induced differentiation factor
chr3_+_80362858 0.02 ENSRNOT00000021353
ENSRNOT00000086242
LDL receptor related protein 4
chr3_-_168111920 0.02 ENSRNOT00000046011
cytochrome P450, family 24, subfamily a, polypeptide 1
chr16_-_54137660 0.02 ENSRNOT00000085435
pericentriolar material 1
chr1_+_192025357 0.02 ENSRNOT00000025072
ubiquitin family domain containing 1
chr2_-_218951030 0.02 ENSRNOT00000019172
solute carrier family 30 member 7
chr9_+_65478496 0.02 ENSRNOT00000016060
NADH:ubiquinone oxidoreductase subunit B3
chr12_+_45905371 0.02 ENSRNOT00000039275
heat shock protein family B (small) member 8
chr16_-_7758189 0.02 ENSRNOT00000026588
2-hydroxyacyl-CoA lyase 1
chr1_-_241460868 0.02 ENSRNOT00000054776
similar to RIKEN cDNA 1700028P14
chr2_+_22427474 0.02 ENSRNOT00000061761
metaxin 3
chr15_-_43667029 0.02 ENSRNOT00000014798
BCL2/adenovirus E1B interacting protein 3-like
chr17_-_78735324 0.02 ENSRNOT00000036299
cerebral dopamine neurotrophic factor
chr10_-_91807937 0.02 ENSRNOT00000005074
wingless-type MMTV integration site family, member 9B
chr1_+_72380711 0.02 ENSRNOT00000022236
FLT3-interacting zinc finger 1
chr1_+_264756499 0.02 ENSRNOT00000031018
progressive external ophthalmoplegia 1
chr2_+_188844073 0.02 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr13_+_100817359 0.02 ENSRNOT00000004330
tumor protein p53 binding protein, 2
chr2_+_2456735 0.02 ENSRNOT00000032974
elongation factor for RNA polymerase II 2
chr12_+_37923528 0.02 ENSRNOT00000045223
ATP binding cassette subfamily B member 9
chr16_+_20395845 0.02 ENSRNOT00000078108
microtubule associated serine/threonine kinase 3
chr1_-_78573374 0.02 ENSRNOT00000090519
Rho GTPase activating protein 35
chrX_-_142131545 0.02 ENSRNOT00000077402
fibroblast growth factor 13
chrX_+_20316893 0.02 ENSRNOT00000082177
WNK lysine deficient protein kinase 3
chr13_+_70174936 0.02 ENSRNOT00000064068
ENSRNOT00000079861
ENSRNOT00000092562
actin related protein 2/3 complex, subunit 5
chr5_-_144479306 0.02 ENSRNOT00000087697
argonaute 1, RISC catalytic component
chr4_-_62438958 0.02 ENSRNOT00000014010
WD repeat domain 91
chr9_-_17114177 0.02 ENSRNOT00000061185
leucine rich repeat containing 73
chr3_-_81282157 0.02 ENSRNOT00000051258
LARGE xylosyl- and glucuronyltransferase 2
chr8_-_1450138 0.02 ENSRNOT00000008062
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr6_-_29483460 0.02 ENSRNOT00000007160
kelch-like family member 29
chr10_+_13000090 0.02 ENSRNOT00000004845
claudin 6
chr1_-_54748763 0.02 ENSRNOT00000074549
protein MAL2-like
chr8_+_64364741 0.02 ENSRNOT00000082840
CUGBP, Elav-like family member 6
chr13_-_70174565 0.02 ENSRNOT00000067135
ral guanine nucleotide dissociation stimulator,-like 1
chr19_-_10360310 0.02 ENSRNOT00000087100
katanin regulatory subunit B1
chr7_-_75098331 0.02 ENSRNOT00000013344
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr20_-_3397039 0.02 ENSRNOT00000001084
ENSRNOT00000085259
protein phosphatase 1, regulatory subunit 18
chr11_-_53731779 0.01 ENSRNOT00000002684
intraflagellar transport 57
chr18_+_15298978 0.01 ENSRNOT00000021263
trafficking protein particle complex 8
chr19_-_43714418 0.01 ENSRNOT00000047179
WD repeat domain 59
chr1_+_86996093 0.01 ENSRNOT00000027425
ENSRNOT00000027494
heterogeneous nuclear ribonucleoprotein L
chr3_+_152552822 0.01 ENSRNOT00000089719
erythrocyte membrane protein band 4.1-like 1
chr10_-_97896525 0.01 ENSRNOT00000005172
WD repeat domain, phosphoinositide interacting 1
chr3_-_157099306 0.01 ENSRNOT00000022861
chromodomain helicase DNA binding protein 6
chr13_+_48607308 0.01 ENSRNOT00000063882
solute carrier family 41 member 1
chr16_-_54137485 0.01 ENSRNOT00000014202
pericentriolar material 1
chr15_+_106257650 0.01 ENSRNOT00000014859
ENSRNOT00000072538
importin 5
chr8_-_25904564 0.01 ENSRNOT00000082744
ENSRNOT00000064783
T-box 20
chr1_-_212568224 0.01 ENSRNOT00000024976
fucose mutarotase-like
chr7_+_142239035 0.01 ENSRNOT00000006239
DAZ associated protein 2
chr20_-_7397448 0.01 ENSRNOT00000059426
similar to chromosome 6 open reading frame 106 isoform a
chr1_+_221420271 0.01 ENSRNOT00000028481
similar to Finkel-Biskis-Reilly murine sarcoma virusubiquitously expressed
chr12_-_24724997 0.01 ENSRNOT00000025560
abhydrolase domain containing 11
chr8_-_12993651 0.01 ENSRNOT00000033932
lysine demethylase 4D
chr6_+_55648021 0.01 ENSRNOT00000064822
ENSRNOT00000091488
ankyrin repeat and MYND domain containing 2
chr6_-_51257625 0.01 ENSRNOT00000012004
HMG-box transcription factor 1
chr16_-_14210449 0.01 ENSRNOT00000016494
coiled-coil serine-rich protein 2
chr3_-_121822436 0.01 ENSRNOT00000039794
cytoskeleton associated protein 2-like
chr1_+_192025710 0.01 ENSRNOT00000077457
ubiquitin family domain containing 1
chr17_+_86408151 0.01 ENSRNOT00000022734
OTU deubiquitinase 1
chr9_-_82514399 0.01 ENSRNOT00000026799
aspartyl aminopeptidase
chr3_+_2462466 0.01 ENSRNOT00000014087
ring finger protein 208
chr3_+_160391106 0.01 ENSRNOT00000016981
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr5_+_136406308 0.01 ENSRNOT00000072492
ERI1 exoribonuclease family member 3
chr3_+_103866144 0.01 ENSRNOT00000007688
katanin regulatory subunit B1 like 1
chr13_-_83504494 0.01 ENSRNOT00000004083
TOR signaling pathway regulator
chr1_+_198120099 0.01 ENSRNOT00000073652
bolA family member 2
chr10_-_94384339 0.01 ENSRNOT00000055125
STE20-related kinase adaptor alpha
chr9_-_100624638 0.01 ENSRNOT00000051155
high density lipoprotein binding protein
chr16_-_71809925 0.01 ENSRNOT00000022425
TM2 domain containing 2
chr1_-_229639187 0.01 ENSRNOT00000016804
zinc finger protein 91
chr14_+_44479614 0.01 ENSRNOT00000003691
UDP-glucose 6-dehydrogenase
chr9_-_17698569 0.01 ENSRNOT00000087528
mitochondrial ribosomal protein L14
chr4_+_118207862 0.01 ENSRNOT00000085787
ENSRNOT00000023103
TIA1 cytotoxic granule-associated RNA binding protein
chr13_+_103300932 0.01 ENSRNOT00000085214
ENSRNOT00000038264
glutamyl-prolyl-tRNA synthetase
chr3_+_118144596 0.01 ENSRNOT00000012447
ENSRNOT00000079023
galactokinase 2
chr3_-_60795951 0.01 ENSRNOT00000002174
activating transcription factor 2
chrX_+_156463953 0.01 ENSRNOT00000079889
filamin A
chr1_-_192025350 0.01 ENSRNOT00000071946
glutamyl-tRNA synthetase 2, mitochondrial
chr1_-_214074663 0.01 ENSRNOT00000026215
chitinase domain-containing protein 1-like
chr7_+_74047814 0.01 ENSRNOT00000014879
odd-skipped related transciption factor 2
chr1_-_221041401 0.01 ENSRNOT00000064136
pecanex homolog 3 (Drosophila)
chr8_+_70994563 0.01 ENSRNOT00000051504
ENSRNOT00000077163
spastic paraplegia 21 homolog (human)
chr8_+_91464229 0.01 ENSRNOT00000013249
branched chain keto acid dehydrogenase E1 subunit beta
chr6_-_92760018 0.01 ENSRNOT00000009560
tripartite motif-containing 9
chr4_+_157563990 0.01 ENSRNOT00000024618
acrosin binding protein
chr10_-_16689321 0.01 ENSRNOT00000028173
BCL2/adenovirus E1B interacting protein 1
chr16_+_71810377 0.01 ENSRNOT00000041330
ADAM metallopeptidase domain 9
chr6_-_72462657 0.01 ENSRNOT00000088720
ENSRNOT00000077578
striatin 3
chrX_-_157139291 0.01 ENSRNOT00000092123
solute carrier family 6 member 8
chr5_-_144996431 0.01 ENSRNOT00000016992
zinc finger MYM-type containing 4
chr17_+_82065937 0.01 ENSRNOT00000051349
ADP-ribosylation factor like GTPase 5B
chr3_+_111478382 0.01 ENSRNOT00000056392
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr10_-_10550138 0.01 ENSRNOT00000067932
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr18_+_65155685 0.01 ENSRNOT00000081797
transcription factor 4
chr1_+_219759183 0.01 ENSRNOT00000026316
pyruvate carboxylase
chr15_+_344685 0.01 ENSRNOT00000065542
ENSRNOT00000066928
potassium calcium-activated channel subfamily M alpha 1
chr4_+_57050214 0.01 ENSRNOT00000025165
adenosylhomocysteinase-like 2
chr6_+_92568975 0.01 ENSRNOT00000036933
abhydrolase domain containing 12B
chr10_+_89376530 0.01 ENSRNOT00000028089
Rho family GTPase 2
chr9_-_99651813 0.01 ENSRNOT00000022089
NADH:ubiquinone oxidoreductase subunit A10
chr13_+_25966428 0.01 ENSRNOT00000061814
ENSRNOT00000003870
zinc finger CCHC-type containing 2
chr5_+_47853818 0.01 ENSRNOT00000009228
ENSRNOT00000079656
caspase 8 associated protein 2
chrX_+_17540458 0.01 ENSRNOT00000045710
nudix hydrolase 11
chr7_-_2986935 0.01 ENSRNOT00000081125
ENSRNOT00000006578
proliferation-associated 2G4
chr3_+_2625015 0.01 ENSRNOT00000018927
neural proliferation, differentiation and control, 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.0 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0048865 stem cell fate commitment(GO:0048865)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.0 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.1 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)