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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Sp100
Z-value: 0.60
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Transcription factors associated with Sp100
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sp100 | rn6_v1_chr9_+_92681078_92681078 | -0.71 | 1.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_-_3793985 Show fit | 0.78 |
ENSRNOT00000049540
ENSRNOT00000086293 |
RT1 class I, locus CE16 |
|
| chr15_-_42794279 Show fit | 0.23 |
ENSRNOT00000023385
|
epoxide hydrolase 2 |
|
| chr2_+_206342066 Show fit | 0.23 |
ENSRNOT00000026556
|
protein tyrosine phosphatase, non-receptor type 22 |
|
| chr2_-_113616766 Show fit | 0.21 |
ENSRNOT00000016858
ENSRNOT00000074723 |
transmembrane protein 212 |
|
| chr3_+_161121697 Show fit | 0.19 |
ENSRNOT00000036020
|
WAP four-disulfide core domain 10A |
|
| chr1_+_61786900 Show fit | 0.17 |
ENSRNOT00000090287
|
|
|
| chr5_+_10125070 Show fit | 0.15 |
ENSRNOT00000085321
|
|
|
| chr5_+_6373583 Show fit | 0.13 |
ENSRNOT00000084749
|
|
|
| chr15_+_24159647 Show fit | 0.13 |
ENSRNOT00000082675
|
galectin 3 |
|
| chrM_+_3904 Show fit | 0.12 |
ENSRNOT00000040993
|
mitochondrially encoded NADH dehydrogenase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Sp100
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:1900673 | olefin metabolic process(GO:1900673) |
| 0.1 | 0.2 | GO:0071663 | positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) |
| 0.0 | 0.1 | GO:1903769 | negative regulation of cell proliferation in bone marrow(GO:1903769) |
| 0.0 | 0.1 | GO:1904612 | glucuronoside metabolic process(GO:0019389) response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) |
| 0.0 | 0.1 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
| 0.0 | 0.1 | GO:0052203 | modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 0.0 | 0.1 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.0 | 0.1 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 0.0 | 0.1 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 0.1 | GO:2000384 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.1 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.1 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.0 | 0.1 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.0 | 0.1 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.0 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.2 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.0 | 0.1 | GO:0050785 | IgE binding(GO:0019863) advanced glycation end-product receptor activity(GO:0050785) |
| 0.0 | 0.1 | GO:0043734 | DNA-N1-methyladenine dioxygenase activity(GO:0043734) |
| 0.0 | 0.1 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 0.1 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 0.0 | 0.1 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 0.1 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.0 | 0.1 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |