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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Sox8

Z-value: 0.26

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Transcription factors associated with Sox8

Gene Symbol Gene ID Gene Info
ENSRNOG00000018841 SRY box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox8rn6_v1_chr10_-_14937336_149373360.523.7e-01Click!

Activity profile of Sox8 motif

Sorted Z-values of Sox8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_15490717 0.08 ENSRNOT00000091557
beta-1,4-galactosyltransferase 6
chr13_+_34400170 0.08 ENSRNOT00000061516
ENSRNOT00000061515
ENSRNOT00000061513
ENSRNOT00000084506
ENSRNOT00000086641
cytoplasmic linker associated protein 1
chr1_+_99505677 0.08 ENSRNOT00000024645
zinc finger protein 719
chr13_+_52976507 0.07 ENSRNOT00000090599
ENSRNOT00000011324
kinesin family member 21B
chr12_-_19254527 0.07 ENSRNOT00000089349

chr1_+_224882439 0.06 ENSRNOT00000024785
cholinergic receptor, muscarinic 1
chr7_-_140437467 0.06 ENSRNOT00000087181
FK506 binding protein 11
chr16_-_18937562 0.05 ENSRNOT00000080387
NACHT and WD repeat domain containing 1
chr2_+_22909569 0.05 ENSRNOT00000073871
homer scaffolding protein 1
chr1_-_80221417 0.05 ENSRNOT00000072149
FosB proto-oncogene, AP-1 transcription factor subunit
chr17_+_53231343 0.05 ENSRNOT00000021703
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr18_+_17403407 0.04 ENSRNOT00000045150
similar to KIAA1328 protein
chr15_+_41937880 0.04 ENSRNOT00000032514
potassium channel regulator
chr1_-_80221710 0.04 ENSRNOT00000091687
FosB proto-oncogene, AP-1 transcription factor subunit
chr6_+_127282466 0.04 ENSRNOT00000012124
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr9_-_75528644 0.04 ENSRNOT00000019283
erb-b2 receptor tyrosine kinase 4
chr2_-_117454769 0.03 ENSRNOT00000068381
MDS1 and EVI1 complex locus
chr17_-_52477575 0.03 ENSRNOT00000081290
GLI family zinc finger 3
chr1_+_88451958 0.03 ENSRNOT00000074301
zinc finger protein 260-like
chr7_-_15821927 0.03 ENSRNOT00000050658
similar to zinc finger protein 101
chr18_+_76559811 0.03 ENSRNOT00000084621
par-6 family cell polarity regulator gamma
chr20_+_27954433 0.02 ENSRNOT00000064288
LIM zinc finger domain containing 1
chr13_-_73055631 0.02 ENSRNOT00000081892
xenotropic and polytropic retrovirus receptor 1
chr4_-_150485781 0.02 ENSRNOT00000008763
zinc finger protein 248
chr16_-_20641908 0.02 ENSRNOT00000026846
elongation factor for RNA polymerase II
chr1_+_99486253 0.01 ENSRNOT00000074820
uncharacterized LOC102546648
chrX_+_77230180 0.01 ENSRNOT00000085879
toll-like receptor 13
chr8_-_60752047 0.01 ENSRNOT00000048115

chr20_+_1787174 0.01 ENSRNOT00000072824
ENSRNOT00000041883
olfactory receptor 1738
chr6_-_132972511 0.01 ENSRNOT00000082216
brain-enriched guanylate kinase-associated
chr8_-_33661049 0.00 ENSRNOT00000068037
Fli-1 proto-oncogene, ETS transcription factor
chr9_+_65110330 0.00 ENSRNOT00000033068
ENSRNOT00000092868
aldehyde oxidase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)