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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Sox6_Sox9
Z-value: 0.49
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Transcription factors associated with Sox6_Sox9
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox9 | rn6_v1_chr10_+_101288489_101288489 | 0.34 | 5.8e-01 | Click! |
| Sox6 | rn6_v1_chr1_+_185673177_185673177 | 0.24 | 6.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_26211445 Show fit | 0.31 |
ENSRNOT00000027739
|
neuronal regeneration related protein |
|
| chr17_-_57394985 Show fit | 0.22 |
ENSRNOT00000019968
|
enhancer of polycomb homolog 1 |
|
| chr3_+_155160481 Show fit | 0.22 |
ENSRNOT00000021133
|
protein phosphatase 1, regulatory subunit 16B |
|
| chr1_-_190965115 Show fit | 0.20 |
ENSRNOT00000023483
|
|
|
| chr8_+_5967463 Show fit | 0.19 |
ENSRNOT00000086251
|
transmembrane protein 123 |
|
| chr4_+_84423653 Show fit | 0.18 |
ENSRNOT00000012655
|
chimerin 2 |
|
| chr8_-_68038533 Show fit | 0.18 |
ENSRNOT00000018756
|
SKI family transcriptional corepressor 1 |
|
| chr18_+_30562178 Show fit | 0.15 |
ENSRNOT00000040998
|
protocadherin beta-16-like |
|
| chr18_+_30890869 Show fit | 0.15 |
ENSRNOT00000060466
|
protocadherin gamma subfamily B, 6 |
|
| chr6_+_110624856 Show fit | 0.13 |
ENSRNOT00000014017
|
vasohibin 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Sox6_Sox9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.1 | 0.2 | GO:0035607 | ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) |
| 0.0 | 0.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.2 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 0.1 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.0 | 0.1 | GO:1900095 | random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.0 | 0.1 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.0 | 0.1 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.0 | 0.1 | GO:0019417 | sulfur oxidation(GO:0019417) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.1 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.0 | 0.1 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.1 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.0 | 0.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.0 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.0 | 0.0 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.0 | 0.0 | GO:1990907 | Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF complex(GO:1990907) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0001565 | phorbol ester receptor activity(GO:0001565) |
| 0.0 | 0.2 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.2 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.1 | GO:0035827 | rubidium ion transmembrane transporter activity(GO:0035827) |
| 0.0 | 0.1 | GO:0030977 | taurine binding(GO:0030977) |
| 0.0 | 0.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 0.0 | 0.1 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 0.1 | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489) |
| 0.0 | 0.1 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 0.1 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |