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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Sox5_Sry
Z-value: 0.65
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Transcription factors associated with Sox5_Sry
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox5 | rn6_v1_chr4_-_178441547_178441547 | -0.88 | 4.9e-02 | Click! |
| Sry | rn6_v1_chrY_+_327166_327166 | -0.08 | 9.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_26211445 Show fit | 0.88 |
ENSRNOT00000027739
|
neuronal regeneration related protein |
|
| chr9_+_25410669 Show fit | 0.36 |
ENSRNOT00000030912
ENSRNOT00000090920 |
transcription factor AP-2 beta |
|
| chr6_-_125723944 Show fit | 0.33 |
ENSRNOT00000007004
|
fibulin 5 |
|
| chr5_-_12563429 Show fit | 0.31 |
ENSRNOT00000059625
|
suppression of tumorigenicity 18 |
|
| chr6_-_125723732 Show fit | 0.30 |
ENSRNOT00000084815
|
fibulin 5 |
|
| chr4_+_44774741 Show fit | 0.26 |
ENSRNOT00000086902
|
MET proto-oncogene, receptor tyrosine kinase |
|
| chr4_-_99305812 Show fit | 0.24 |
ENSRNOT00000038912
|
required for meiotic nuclear division 5 homolog A |
|
| chr11_+_61083757 Show fit | 0.23 |
ENSRNOT00000002790
|
BOC cell adhesion associated, oncogene regulated |
|
| chr14_+_17492081 Show fit | 0.21 |
ENSRNOT00000003346
|
G3BP stress granule assembly factor 2 |
|
| chr10_+_23661013 Show fit | 0.20 |
ENSRNOT00000076664
|
early B-cell factor 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Sox5_Sry
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0031103 | axon regeneration(GO:0031103) |
| 0.1 | 0.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.4 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.1 | 0.4 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
| 0.0 | 0.4 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 0.2 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.0 | 0.2 | GO:1904646 | cellular response to beta-amyloid(GO:1904646) |
| 0.0 | 0.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 0.2 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 0.0 | 0.2 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 0.2 | GO:0034657 | GID complex(GO:0034657) |
| 0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.1 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.0 | 0.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.1 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.1 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.0 | GO:1990032 | parallel fiber(GO:1990032) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 0.2 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.2 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.1 | GO:0030977 | taurine binding(GO:0030977) |
| 0.0 | 0.1 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 0.1 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.1 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.0 | 0.1 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.1 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.1 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 0.1 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |