ISMARA results: Smarcc1

Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

Navigation

Downloads

Results for Smarcc1_Fosl1

Z-value: 0.72

Motif logo

Transcription factors associated with Smarcc1_Fosl1

Gene Symbol	Gene ID	Gene Info
Smarcc1 NCBI RGD Ensembl	ENSRNOG00000020804	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Fosl1 NCBI RGD Ensembl	ENSRNOG00000020552	FOS like 1, AP-1 transcription factor subunit

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Smarcc1	rn6_v1_chr8_+_118206698_118206703	-0.26	6.7e-01	Click!
Fosl1	rn6_v1_chr1_+_220826560_220826560	0.09	8.9e-01	Click!

Activity profile of Smarcc1_Fosl1 motif

Sorted Z-values of Smarcc1_Fosl1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_145870912 Show fit	0.59	ENSRNOT00000016289	Il16 NCBI RGD Ensembl Show fit	interleukin 16
chr12_-_48365784 Show fit	0.56	ENSRNOT00000077317	Dao NCBI RGD Ensembl Show fit	D-amino-acid oxidase
chr20_+_5067330 Show fit	0.55	ENSRNOT00000037482	Ly6g6e NCBI RGD Ensembl Show fit	lymphocyte antigen 6 complex, locus G6E
chr4_+_86275717 Show fit	0.53	ENSRNOT00000016414	Ppp1r17 NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 17
chr2_+_190003223 Show fit	0.50	ENSRNOT00000015712	S100a5 NCBI RGD Ensembl Show fit	S100 calcium binding protein A5
chr17_-_2705123 Show fit	0.30	ENSRNOT00000024940	Olr1652 NCBI RGD Ensembl Show fit	olfactory receptor 1652
chr3_+_161121697 Show fit	0.29	ENSRNOT00000036020	Wfdc10a NCBI RGD Ensembl Show fit	WAP four-disulfide core domain 10A
chr1_+_12006660 Show fit	0.25	ENSRNOT00000093439	Mcc NCBI RGD Ensembl Show fit	colorectal mutant cancer protein
chr1_+_218466289 Show fit	0.24	ENSRNOT00000017948	Mrgprf NCBI RGD Ensembl Show fit	MAS related GPR family member F
chr9_+_15166118 Show fit	0.22	ENSRNOT00000020432	Mdfi NCBI RGD Ensembl Show fit	MyoD family inhibitor

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Smarcc1_Fosl1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080) D-amino acid metabolic process(GO:0046416)
0.0	0.6	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.5	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1	0.3	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.1	0.3	GO:0009608	response to symbiont(GO:0009608)
0.0	0.3	GO:0035747	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1	0.2	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	0.2	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0	0.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)

Showing 1 to 10 of 143 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0070557	PCNA-p21 complex(GO:0070557)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.1	GO:0034774	secretory granule lumen(GO:0034774)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)

Showing 1 to 10 of 31 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.6	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.6	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.3	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.3	GO:0005549	odorant binding(GO:0005549)
0.0	0.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.2	GO:0008481	sphinganine kinase activity(GO:0008481)

Showing 1 to 10 of 83 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Total log-likelihood	Term	Description
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events

Showing 1 to 7 of 7 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Total log-likelihood	Term	Description
0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins

Showing 1 to 8 of 8 entries

Results for Smarcc1_Fosl1

Z-value: 0.72

Motif logo

Transcription factors associated with Smarcc1_Fosl1

Activity-expression correlation:

Activity profile of Smarcc1_Fosl1 motif

Sorted Z-values of Smarcc1_Fosl1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Smarcc1_Fosl1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: