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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Rxra
Z-value: 0.40
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Transcription factors associated with Rxra
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rxra | rn6_v1_chr3_+_6211789_6211789 | -0.13 | 8.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_+_91054974 Show fit | 0.20 |
ENSRNOT00000091089
|
C-reactive protein |
|
| chr3_+_124896618 Show fit | 0.18 |
ENSRNOT00000028888
|
CDP-diacylglycerol synthase 2 |
|
| chr4_+_88832178 Show fit | 0.17 |
ENSRNOT00000088983
|
ATP-binding cassette, subfamily G (WHITE), member 2 |
|
| chr2_+_149899836 Show fit | 0.15 |
ENSRNOT00000086481
|
similar to hypothetical protein C130079G13 |
|
| chr2_-_140618405 Show fit | 0.15 |
ENSRNOT00000017736
|
SET domain containing (lysine methyltransferase) 7 |
|
| chr7_-_82687130 Show fit | 0.15 |
ENSRNOT00000006791
|
transmembrane protein 74 |
|
| chr10_+_55169282 Show fit | 0.14 |
ENSRNOT00000005423
|
coiled-coil domain containing 42 |
|
| chr16_-_32868680 Show fit | 0.12 |
ENSRNOT00000015974
ENSRNOT00000082392 |
aminoadipate aminotransferase |
|
| chr18_+_45023932 Show fit | 0.11 |
ENSRNOT00000039379
|
family with sequence similarity 170, member A |
|
| chr3_-_111037425 Show fit | 0.11 |
ENSRNOT00000085628
|
protein phosphatase 1, regulatory (inhibitor) subunit 14D |
Network of associatons between targets according to the STRING database.
First level regulatory network of Rxra
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:1904612 | response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) |
| 0.0 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.0 | 0.2 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.0 | 0.1 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
| 0.0 | 0.1 | GO:2001106 | fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 0.1 | GO:0001757 | somite specification(GO:0001757) |
| 0.0 | 0.1 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.0 | 0.1 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.0 | 0.1 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 0.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
| 0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.2 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.0 | 0.1 | GO:0036137 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
| 0.0 | 0.1 | GO:0016433 | rRNA (adenine) methyltransferase activity(GO:0016433) |
| 0.0 | 0.1 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.1 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.0 | 0.0 | GO:0032551 | UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.0 | 0.0 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.0 | 0.0 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.1 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.1 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |