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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Runx1
Z-value: 0.50
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Transcription factors associated with Runx1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Runx1 | rn6_v1_chr11_-_33003021_33003021 | 0.48 | 4.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_187742747 Show fit | 0.33 |
ENSRNOT00000026530
|
bone gamma-carboxyglutamate protein |
|
| chr10_-_85435016 Show fit | 0.28 |
ENSRNOT00000079921
|
RIKEN cDNA 4933428G20 gene |
|
| chr14_-_78902063 Show fit | 0.18 |
ENSRNOT00000088469
|
protein phosphatase 2, regulatory subunit B, gamma |
|
| chr1_+_44311513 Show fit | 0.17 |
ENSRNOT00000065386
|
T-cell lymphoma invasion and metastasis 2 |
|
| chr18_-_55916220 Show fit | 0.17 |
ENSRNOT00000025934
|
synaptopodin |
|
| chr20_-_22459025 Show fit | 0.16 |
ENSRNOT00000000792
|
early growth response 2 |
|
| chr10_-_38985466 Show fit | 0.15 |
ENSRNOT00000010121
|
interleukin 13 |
|
| chr13_-_83202864 Show fit | 0.13 |
ENSRNOT00000003976
|
X-C motif chemokine ligand 1 |
|
| chr9_-_15700235 Show fit | 0.13 |
ENSRNOT00000088713
ENSRNOT00000035907 |
transcriptional regulating factor 1 |
|
| chr1_+_100577056 Show fit | 0.12 |
ENSRNOT00000026992
|
napsin A aspartic peptidase |
Network of associatons between targets according to the STRING database.
First level regulatory network of Runx1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.1 | 0.2 | GO:0002380 | immunoglobulin secretion involved in immune response(GO:0002380) |
| 0.1 | 0.2 | GO:2000538 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.0 | 0.2 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.0 | 0.2 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
| 0.0 | 0.2 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.1 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.0 | 0.1 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.0 | 0.1 | GO:2000872 | positive regulation of progesterone secretion(GO:2000872) |
| 0.0 | 0.1 | GO:0034628 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.0 | 0.1 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.0 | 0.1 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 0.1 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.1 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.0 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.0 | 0.1 | GO:0072590 | N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) |
| 0.0 | 0.1 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.0 | 0.1 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.0 | 0.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.0 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |