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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Rreb1
Z-value: 0.61
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Transcription factors associated with Rreb1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rreb1 | rn6_v1_chr17_-_27602934_27602934 | 0.74 | 1.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_100577056 Show fit | 0.82 |
ENSRNOT00000026992
|
napsin A aspartic peptidase |
|
| chr5_-_100647727 Show fit | 0.21 |
ENSRNOT00000067435
|
nuclear factor I/B |
|
| chr4_+_88834066 Show fit | 0.21 |
ENSRNOT00000009546
|
ATP-binding cassette, subfamily G (WHITE), member 2 |
|
| chr12_-_37574750 Show fit | 0.20 |
ENSRNOT00000066253
|
lysine methyltransferase 5A |
|
| chr17_-_32661865 Show fit | 0.17 |
ENSRNOT00000022194
|
serpin family B member 9 |
|
| chr8_-_129919120 Show fit | 0.17 |
ENSRNOT00000074423
|
unc-51 like kinase 4 |
|
| chr1_-_42486035 Show fit | 0.17 |
ENSRNOT00000025398
|
mitochondrial translational release factor 1-like |
|
| chr20_+_4363508 Show fit | 0.17 |
ENSRNOT00000077205
|
advanced glycosylation end product-specific receptor |
|
| chr2_-_22798214 Show fit | 0.17 |
ENSRNOT00000016135
|
poly(A) RNA polymerase D4, non-canonical |
|
| chr12_-_25638797 Show fit | 0.16 |
ENSRNOT00000002033
|
GATS protein-like 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Rreb1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.1 | 0.3 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) |
| 0.1 | 0.2 | GO:0019389 | glucuronoside metabolic process(GO:0019389) response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) |
| 0.1 | 0.2 | GO:1905204 | response to selenite ion(GO:0072714) negative regulation of connective tissue replacement(GO:1905204) |
| 0.0 | 0.2 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.0 | 0.2 | GO:0033668 | negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) |
| 0.0 | 0.2 | GO:0048669 | somite specification(GO:0001757) collateral sprouting in absence of injury(GO:0048669) |
| 0.0 | 0.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 0.2 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.0 | 0.1 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.0 | 0.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.2 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 0.1 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.0 | 0.1 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.1 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.0 | 0.1 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.0 | 0.2 | GO:0016149 | translation release factor activity, codon specific(GO:0016149) |
| 0.0 | 0.2 | GO:0050785 | advanced glycation end-product receptor activity(GO:0050785) |
| 0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.2 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.0 | 0.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.1 | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489) |
| 0.0 | 0.1 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.0 | 0.1 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.2 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.2 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.2 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |