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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Rora

Z-value: 0.34

Motif logo

Transcription factors associated with Rora

Gene Symbol Gene ID Gene Info
ENSRNOG00000027145 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rorarn6_v1_chr8_+_75516904_755169040.059.4e-01Click!

Activity profile of Rora motif

Sorted Z-values of Rora motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_61531416 0.15 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr4_+_51614676 0.14 ENSRNOT00000060494
ankyrin repeat and SOCS box containing 15
chr8_+_29453643 0.12 ENSRNOT00000090643
opioid binding protein/cell adhesion molecule-like
chr10_-_85517683 0.11 ENSRNOT00000016070
SRC kinase signaling inhibitor 1
chr3_-_93789617 0.11 ENSRNOT00000078616
cell cycle associated protein 1
chr7_+_121311024 0.10 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr1_+_100593892 0.10 ENSRNOT00000027062
potassium voltage-gated channel subfamily C member 3
chr6_-_76552559 0.10 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr12_+_40018937 0.09 ENSRNOT00000001697
cut-like homeobox 2
chr3_+_134413170 0.09 ENSRNOT00000074338

chr1_+_100593680 0.09 ENSRNOT00000078153
ENSRNOT00000027063
potassium voltage-gated channel subfamily C member 3
chr3_-_80012750 0.08 ENSRNOT00000018154
nuclear receptor subfamily 1, group H, member 3
chr8_-_82533689 0.08 ENSRNOT00000014124
tropomodulin 2
chr3_-_146396299 0.08 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr3_+_177226417 0.08 ENSRNOT00000031328
opioid related nociceptin receptor 1
chr1_-_49844547 0.08 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr16_-_32753278 0.08 ENSRNOT00000015759
microfibrillar-associated protein 3-like
chr6_-_3355339 0.08 ENSRNOT00000084602
mitogen-activated protein kinase kinase kinase kinase 3
chr10_-_86688730 0.08 ENSRNOT00000055333
nuclear receptor subfamily 1, group D, member 1
chr10_-_90240509 0.08 ENSRNOT00000028407
ataxin 7-like 3
chr8_+_114867062 0.08 ENSRNOT00000074771
WD repeat domain 82
chr5_+_147069616 0.07 ENSRNOT00000072908
tripartite motif-containing 62
chr2_+_28460068 0.07 ENSRNOT00000066819
forkhead box D1
chr7_-_81592206 0.07 ENSRNOT00000007979
angiopoietin 1
chr2_-_113345577 0.07 ENSRNOT00000034096
fibronectin type III domain containing 3B
chr14_-_114583122 0.07 ENSRNOT00000084595
spectrin, beta, non-erythrocytic 1
chr15_+_61069581 0.07 ENSRNOT00000084333
von Willebrand factor A domain containing 8
chr1_+_224882439 0.06 ENSRNOT00000024785
cholinergic receptor, muscarinic 1
chr20_+_28572242 0.06 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr1_+_197659187 0.06 ENSRNOT00000082228
serine/threonine-protein kinase SBK1
chr10_-_104748003 0.06 ENSRNOT00000042372
ENSRNOT00000046754
acyl-CoA oxidase 1
chr3_+_14304591 0.06 ENSRNOT00000007776
centriolin
chr2_-_56679955 0.06 ENSRNOT00000016722
EGF-like, fibronectin type III and laminin G domains
chr1_-_221041401 0.06 ENSRNOT00000064136
pecanex homolog 3 (Drosophila)
chr3_-_72113680 0.06 ENSRNOT00000009708
zinc finger, DHHC-type containing 5
chr10_+_55712043 0.06 ENSRNOT00000010141
arachidonate lipoxygenase 3
chr3_+_151126591 0.06 ENSRNOT00000025859
myosin heavy chain 7B
chr3_-_60765645 0.06 ENSRNOT00000050513
activating transcription factor 2
chr1_-_73732118 0.06 ENSRNOT00000077964
leukocyte receptor cluster member 8
chr7_-_62972084 0.05 ENSRNOT00000064251
methionine sulfoxide reductase B3
chr1_-_88066101 0.05 ENSRNOT00000079473
ENSRNOT00000027893
ryanodine receptor 1
chr18_+_30856847 0.05 ENSRNOT00000027019

chr1_+_205706468 0.05 ENSRNOT00000089957
ENSRNOT00000023877
erythroid differentiation regulatory factor 1
chr5_-_147412705 0.05 ENSRNOT00000010688
similar to mKIAA1522 protein
chr7_-_12393266 0.05 ENSRNOT00000021709
ephrin A2
chr11_-_87977368 0.05 ENSRNOT00000002546
transmembrane protein 191C
chr10_+_59000397 0.05 ENSRNOT00000021134
MYB binding protein 1a
chr17_-_18592750 0.05 ENSRNOT00000065742
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr7_-_12424367 0.05 ENSRNOT00000060698
midnolin
chr13_-_86451002 0.05 ENSRNOT00000043004
ENSRNOT00000027996
PBX homeobox 1
chr9_+_10471742 0.05 ENSRNOT00000072276
scaffold attachment factor B2
chr7_-_114590119 0.05 ENSRNOT00000079599
protein tyrosine kinase 2
chr6_+_12362813 0.05 ENSRNOT00000022370
stonin 1
chr4_+_49369296 0.05 ENSRNOT00000007822
wingless-type MMTV integration site family, member 16
chr8_+_59900651 0.04 ENSRNOT00000020410
transmembrane protein 266
chr8_+_33239139 0.04 ENSRNOT00000011589
Rho GTPase activating protein 32
chr8_+_117280705 0.04 ENSRNOT00000085038
ubiquitin specific peptidase 19
chr3_+_155297566 0.04 ENSRNOT00000021435
ENSRNOT00000084866
DEAH-box helicase 35
chr3_-_112789282 0.04 ENSRNOT00000090680
ENSRNOT00000066181
tau tubulin kinase 2
chr1_-_222350173 0.04 ENSRNOT00000030625
fibronectin leucine rich transmembrane protein 1
chr19_-_26053762 0.04 ENSRNOT00000004646
microtubule associated serine/threonine kinase 1
chr6_-_28994519 0.04 ENSRNOT00000006668
UBX domain protein 2A
chr7_+_73273985 0.03 ENSRNOT00000077730
POP1 homolog, ribonuclease P/MRP subunit
chr10_-_82399484 0.03 ENSRNOT00000082972
ENSRNOT00000055582
xylosyltransferase 2
chr20_+_3351303 0.03 ENSRNOT00000080419
ENSRNOT00000001065
ENSRNOT00000086503
alpha tubulin acetyltransferase 1
chr3_-_113525864 0.03 ENSRNOT00000046659
FERM domain containing 5
chr1_-_78968329 0.03 ENSRNOT00000023078
protein phosphatase 5, catalytic subunit
chr14_+_4125380 0.03 ENSRNOT00000002882
zinc finger protein 644
chr1_-_265542276 0.03 ENSRNOT00000065172
meningioma expressed antigen 5 (hyaluronidase)
chrX_+_25016401 0.03 ENSRNOT00000059270
chloride voltage-gated channel 4
chr13_+_110677810 0.03 ENSRNOT00000006340
solute carrier family 30 member 1
chr6_+_106496992 0.03 ENSRNOT00000086136
ENSRNOT00000058181
regulator of G-protein signaling 6
chr5_-_147148291 0.03 ENSRNOT00000085151
antizyme inhibitor 2
chr3_+_156727642 0.03 ENSRNOT00000078909
phospholipase C, gamma 1
chr10_-_45579029 0.03 ENSRNOT00000080028
ADP-ribosylation factor 1
chr9_+_40975836 0.03 ENSRNOT00000084470
protein tyrosine phosphatase, non-receptor type 18
chr1_+_198682230 0.03 ENSRNOT00000023995
zinc finger protein 48
chr10_+_61685241 0.03 ENSRNOT00000092606
MAX network transcriptional repressor
chr9_+_2202511 0.03 ENSRNOT00000017556
SATB homeobox 1
chr5_+_148066062 0.03 ENSRNOT00000084118

chr1_+_61374379 0.02 ENSRNOT00000015343
zinc finger protein 53
chr8_+_39878955 0.02 ENSRNOT00000060300
roundabout homolog 4-like
chr4_+_152449270 0.02 ENSRNOT00000076733
RAD52 homolog, DNA repair protein
chr10_+_88356615 0.02 ENSRNOT00000022687
kelch-like family member 10
chr1_-_213973163 0.02 ENSRNOT00000024867
cell cycle exit and neuronal differentiation protein 1-like
chrX_+_68774699 0.02 ENSRNOT00000081662
StAR-related lipid transfer domain containing 8
chr9_-_93404883 0.02 ENSRNOT00000025024
neuromedin U receptor 1
chr5_+_172825072 0.02 ENSRNOT00000068525
cilia and flagella associated protein 74
chr2_-_210282352 0.02 ENSRNOT00000075653
solute carrier family 6 member 17
chr18_-_63185510 0.02 ENSRNOT00000024632
AFG3 like matrix AAA peptidase subunit 2
chr4_-_56438465 0.02 ENSRNOT00000064007
RNA binding motif protein 28
chr1_-_126211439 0.02 ENSRNOT00000014988
tight junction protein 1
chr7_+_53630621 0.02 ENSRNOT00000067011
ENSRNOT00000080598
cysteine and glycine-rich protein 2
chr6_-_107678156 0.02 ENSRNOT00000014158
ELM2 and Myb/SANT domain containing 1
chr18_-_1946840 0.02 ENSRNOT00000041878
abhydrolase domain containing 3
chr4_+_7260575 0.02 ENSRNOT00000064893
Fas-activated serine/threonine kinase
chr20_-_14545772 0.02 ENSRNOT00000001766
BCR, RhoGEF and GTPase activating protein
chr8_+_82380757 0.02 ENSRNOT00000013512
LEO1 homolog, Paf1/RNA polymerase II complex component
chr20_-_5618254 0.02 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chr7_+_118685181 0.02 ENSRNOT00000068221
apolipoprotein L, 3
chr10_-_15155412 0.02 ENSRNOT00000026536
hydroxyacylglutathione hydrolase-like
chr8_+_36125999 0.02 ENSRNOT00000013036
ENSRNOT00000088046
kin of IRRE like 3 (Drosophila)
chr17_+_45247776 0.02 ENSRNOT00000081063
ENSRNOT00000080655
zinc finger with KRAB and SCAN domains 3
chr8_-_47404010 0.02 ENSRNOT00000038647
transmembrane protein 136
chr8_+_127171537 0.02 ENSRNOT00000078625
ENSRNOT00000051290
ENSRNOT00000087753
golgin A4
chr11_+_61531571 0.02 ENSRNOT00000093467
ENSRNOT00000002727
ATPase H+ transporting V1 subunit A
chr2_+_208420206 0.02 ENSRNOT00000090500
ENSRNOT00000076065
ENSRNOT00000073644
ENSRNOT00000086279
methylosome protein 50-like
WD repeat domain 77
chr10_+_81693770 0.02 ENSRNOT00000003777
ENSRNOT00000085681
sperm associated antigen 9
chr3_-_2727616 0.01 ENSRNOT00000061904
complement C8 gamma chain
chr3_+_47453821 0.01 ENSRNOT00000081682
TRAF family member-associated NFKB activator
chr4_-_56438142 0.01 ENSRNOT00000077079
RNA binding motif protein 28
chr18_-_31430973 0.01 ENSRNOT00000026065
protocadherin 12
chr2_-_238803024 0.01 ENSRNOT00000046775
tet methylcytosine dioxygenase 2
chr4_-_130659697 0.01 ENSRNOT00000072374
rCG56280-like
chr6_+_2216623 0.01 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr16_+_1979191 0.01 ENSRNOT00000014382
peptidylprolyl isomerase F
chr1_+_80954858 0.01 ENSRNOT00000030440
zinc finger protein 112
chr10_+_14248399 0.01 ENSRNOT00000077689
splA/ryanodine receptor domain and SOCS box containing 3
chr13_+_100817359 0.01 ENSRNOT00000004330
tumor protein p53 binding protein, 2
chrX_-_40086870 0.01 ENSRNOT00000010027
small muscle protein, X-linked
chr4_-_77706994 0.01 ENSRNOT00000038517
zinc finger protein 777
chr13_-_110678389 0.01 ENSRNOT00000082906

chr3_+_125320680 0.01 ENSRNOT00000028891
hypothetical protein LOC681292
chr8_+_48094673 0.01 ENSRNOT00000008614
nectin cell adhesion molecule 1
chr18_+_28653592 0.01 ENSRNOT00000085120
ENSRNOT00000045795
CXXC finger protein 5
chr14_+_81362618 0.01 ENSRNOT00000017386
major facilitator superfamily domain containing 10
chr20_+_27352276 0.01 ENSRNOT00000076534

chr5_+_25168295 0.01 ENSRNOT00000020245
fibrinogen silencer binding protein
chr3_+_154905141 0.01 ENSRNOT00000088748
ENSRNOT00000020556
Ral GTPase activating protein non-catalytic beta subunit
chrX_+_71342775 0.01 ENSRNOT00000004888
integrin subunit beta 1 binding protein 2
chr16_+_3293599 0.01 ENSRNOT00000081999
ENSRNOT00000047118
ENSRNOT00000020427
ELKS/RAB6-interacting/CAST family member 2
chr1_-_134870255 0.01 ENSRNOT00000055829
chromodomain helicase DNA binding protein 2
chr5_-_129113132 0.01 ENSRNOT00000080048
ring finger protein 11-like 1
chr9_-_14550625 0.01 ENSRNOT00000078227
O-acyl-ADP-ribose deacylase 1
chr17_+_6840463 0.01 ENSRNOT00000061233
ubiquilin 1
chr18_-_3555711 0.01 ENSRNOT00000029274
transmembrane protein 241
chr7_-_117288018 0.01 ENSRNOT00000091285
plectin
chr19_-_10653800 0.01 ENSRNOT00000022128
C-X3-C motif chemokine ligand 1
chrX_-_78911601 0.01 ENSRNOT00000003188
similar to RIKEN cDNA 2610002M06
chr15_-_37030240 0.01 ENSRNOT00000028219
ENSRNOT00000088037
paraspeckle component 1
chr20_-_4817146 0.01 ENSRNOT00000080174
DExD-box helicase 39B
chr8_-_116965396 0.01 ENSRNOT00000042528
bassoon (presynaptic cytomatrix protein)
chr1_-_170404056 0.00 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chr18_-_63488027 0.00 ENSRNOT00000023763
protein tyrosine phosphatase, non-receptor type 2
chr8_+_71167305 0.00 ENSRNOT00000021337
RNA binding protein with multiple splicing 2
chr2_+_252305874 0.00 ENSRNOT00000020972
chitobiase
chr13_+_34610684 0.00 ENSRNOT00000093019
ENSRNOT00000003280
transcription factor CP2-like 1
chr3_+_113257688 0.00 ENSRNOT00000019320
microtubule-associated protein 1A
chr19_+_9895121 0.00 ENSRNOT00000033953
protease, serine, 54
chr17_-_15094805 0.00 ENSRNOT00000044073
F-box and WD-40 domain protein 17
chr15_-_4057104 0.00 ENSRNOT00000084350
ENSRNOT00000012270
SEC24 homolog C, COPII coat complex component
chr9_-_99659425 0.00 ENSRNOT00000051686
olfactory receptor 1343
chr4_+_157836912 0.00 ENSRNOT00000067271
sodium channel epithelial 1 alpha subunit
chr7_-_136853154 0.00 ENSRNOT00000087376
neural EGFL like 2
chr1_+_219329574 0.00 ENSRNOT00000071109
calcium binding protein 2
chr7_+_143810892 0.00 ENSRNOT00000016240
zinc finger protein 740
chr12_-_46718355 0.00 ENSRNOT00000030031
RAB35, member RAS oncogene family
chr2_-_111793326 0.00 ENSRNOT00000092660
neuroligin 1
chr5_+_74766636 0.00 ENSRNOT00000030913

chr16_-_69242028 0.00 ENSRNOT00000019002
zinc finger protein 703
chr15_-_3544685 0.00 ENSRNOT00000015179
ENSRNOT00000085126
vinculin
chr2_+_230186198 0.00 ENSRNOT00000013049
ENSRNOT00000092954
caspase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Rora

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0072268 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)