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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Rad21_Smc3

Z-value: 0.76

Motif logo

Transcription factors associated with Rad21_Smc3

Gene Symbol Gene ID Gene Info
ENSRNOG00000004420 RAD21 cohesin complex component
ENSRNOG00000014173 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Smc3rn6_v1_chr1_+_274309758_274309758-0.652.3e-01Click!
Rad21rn6_v1_chr7_-_91538673_91538673-0.533.6e-01Click!

Activity profile of Rad21_Smc3 motif

Sorted Z-values of Rad21_Smc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_9695292 0.82 ENSRNOT00000036162
proline rich 7 (synaptic)
chr3_+_164424515 0.81 ENSRNOT00000083876
CCAAT/enhancer binding protein beta
chr12_+_24651314 0.36 ENSRNOT00000077016
ENSRNOT00000071569
VPS37D, ESCRT-I subunit
chr16_+_19767264 0.35 ENSRNOT00000051802
ENSRNOT00000092073
occludin/ELL domain containing 1
chr3_+_154395187 0.34 ENSRNOT00000050810
V-set and transmembrane domain containing 2 like
chr19_+_41482728 0.34 ENSRNOT00000022943
calbindin 2
chr13_+_75059927 0.33 ENSRNOT00000080801
hypothetical protein LOC680254
chr8_+_71822129 0.32 ENSRNOT00000089147
death-associated protein kinase 2
chrX_+_72684329 0.30 ENSRNOT00000057644
DMRT-like family C1c1
chr16_+_20672374 0.29 ENSRNOT00000063780
similar to RIKEN cDNA 2810428I15
chr20_-_10680283 0.29 ENSRNOT00000001579
salt-inducible kinase 1
chr3_+_177374812 0.29 ENSRNOT00000024096
RNA polymerase III subunit K
chr12_+_48257609 0.29 ENSRNOT00000031658
ENSRNOT00000090277
alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
chr10_-_85049331 0.27 ENSRNOT00000012538
T-box 21
chr11_+_77815181 0.26 ENSRNOT00000002640
claudin 1
chr15_-_29369504 0.26 ENSRNOT00000060297

chr15_-_34444244 0.26 ENSRNOT00000027612
cell death-inducing DFFA-like effector b
chr17_-_13393243 0.25 ENSRNOT00000018252
growth arrest and DNA-damage-inducible, gamma
chr20_+_3935529 0.25 ENSRNOT00000072458
class II histocompatibility antigen, M alpha chain
chr1_+_79959591 0.24 ENSRNOT00000090515
radial spoke head 6 homolog A
chr4_+_25435873 0.24 ENSRNOT00000000018
STEAP family member 1
chr10_-_13051154 0.24 ENSRNOT00000033457

chr1_+_82480195 0.23 ENSRNOT00000028051
transforming growth factor, beta 1
chr3_+_160231914 0.23 ENSRNOT00000014411
potassium two pore domain channel subfamily K member 15
chr9_-_43127887 0.23 ENSRNOT00000021685
ankyrin repeat domain 39
chr3_+_170252901 0.23 ENSRNOT00000005871
melanocortin 3 receptor
chr6_+_137997335 0.22 ENSRNOT00000006872
transmembrane protein 121
chr16_+_19874034 0.22 ENSRNOT00000023579
mitochondrial ribosomal protein L34
chr8_-_117237229 0.22 ENSRNOT00000071381
kelch domain containing 8B
chr9_-_10441834 0.22 ENSRNOT00000043704
ribosomal protein L36
chr7_+_140781799 0.21 ENSRNOT00000087932
DnaJ heat shock protein family (Hsp40) member C22
chr20_-_5244386 0.21 ENSRNOT00000070886
RT1 class II, locus DMa
chr3_-_3798177 0.21 ENSRNOT00000025386
ENSRNOT00000076156
DNL-type zinc finger
chr20_+_4593389 0.21 ENSRNOT00000001174
solute carrier family 44, member 4
chr15_-_23580342 0.20 ENSRNOT00000013331
ENSRNOT00000085767
cornichon family AMPA receptor auxiliary protein 1
chr3_-_52998650 0.20 ENSRNOT00000009988
similar to 40S ribosomal protein S3
chr1_-_198706852 0.19 ENSRNOT00000024074
dCTP pyrophosphatase 1
chr1_-_242152834 0.19 ENSRNOT00000071614
ENSRNOT00000020412
frataxin
chr11_+_88122271 0.19 ENSRNOT00000002540
stromal cell-derived factor 2-like 1
chr3_-_154627257 0.19 ENSRNOT00000018328
transglutaminase 2
chr5_+_143081326 0.19 ENSRNOT00000067204
MYST/Esa1-associated factor 6
chr2_+_225827504 0.19 ENSRNOT00000018343
glutamate cysteine ligase, modifier subunit
chr1_-_89258935 0.19 ENSRNOT00000003180
ribosomal protein L36-like
chr11_+_33845463 0.19 ENSRNOT00000041838
carbonyl reductase 1
chr4_+_62780596 0.18 ENSRNOT00000073846
hypothetical protein LOC689574
chr4_-_171176581 0.17 ENSRNOT00000030850
RAS-like, estrogen-regulated, growth-inhibitor
chr10_-_13187461 0.17 ENSRNOT00000007039
protease, serine, 41
chr3_-_72071895 0.17 ENSRNOT00000082857
selenoprotein H
chr5_+_122508388 0.17 ENSRNOT00000038410
Tctex1 domain containing 1
chrX_+_45637415 0.17 ENSRNOT00000050544
similar to ferritin heavy polypeptide-like 17
chr11_-_67756799 0.17 ENSRNOT00000030975
poly (ADP-ribose) polymerase family, member 9
chr15_-_38276159 0.16 ENSRNOT00000084698
ENSRNOT00000015233
mitochondrial calcium uptake 2
chr16_+_9907598 0.16 ENSRNOT00000027352
protein tyrosine phosphatase, non-receptor type 20
chr16_+_21282467 0.16 ENSRNOT00000065345
YjeF N-terminal domain containing 3
chr10_+_55492404 0.16 ENSRNOT00000005588
ENSRNOT00000078038
ribosomal protein L26
chr5_-_151397603 0.16 ENSRNOT00000076866
G protein-coupled receptor 3
chr1_+_91363492 0.16 ENSRNOT00000014517
CCAAT/enhancer binding protein alpha
chr15_+_32386816 0.15 ENSRNOT00000060322

chr2_+_200397967 0.15 ENSRNOT00000025821
regenerating family member 4
chr7_+_139271698 0.15 ENSRNOT00000079388
solute carrier family 48 member 1
chr5_-_164927869 0.15 ENSRNOT00000012080
dorsal inhibitory axon guidance protein
chr3_+_148150698 0.15 ENSRNOT00000087075
ENSRNOT00000010251
histocompatibility minor 13
chr2_+_190007216 0.15 ENSRNOT00000015612
S100 calcium binding protein A6
chr13_-_110257367 0.15 ENSRNOT00000005576
denticleless E3 ubiquitin protein ligase homolog
chr9_-_92775816 0.15 ENSRNOT00000029635
similar to Nuclear autoantigen Sp-100 (Speckled 100 kDa)
chr2_-_219558675 0.14 ENSRNOT00000020149
RNA terminal phosphate cyclase domain 1
chr3_+_175548174 0.14 ENSRNOT00000091941
adhesion regulating molecule 1
chr20_+_6869767 0.14 ENSRNOT00000000631
ENSRNOT00000086330
ENSRNOT00000093188
ENSRNOT00000093736
similar to GI:13385412-like protein splice form I
chr2_+_86951776 0.14 ENSRNOT00000087275

chr2_-_199771896 0.14 ENSRNOT00000043937
chromodomain helicase DNA binding protein 1-like
chr2_+_251817694 0.14 ENSRNOT00000019964
similar to RIKEN cDNA 2410004B18
chr20_-_3374344 0.14 ENSRNOT00000082999
protein phosphatase 1, regulatory subunit 18
chr17_+_10384511 0.14 ENSRNOT00000024357
synuclein, beta
chrX_-_72078551 0.13 ENSRNOT00000076978
ribosomal protein S4, X-linked
chr1_-_80666566 0.13 ENSRNOT00000082125
ENSRNOT00000025388
nectin cell adhesion molecule 2
chr6_-_11494459 0.13 ENSRNOT00000021570
potassium two pore domain channel subfamily K member 12
chr7_-_138707221 0.13 ENSRNOT00000009199
adhesion molecule with Ig like domain 2
chr17_+_57075218 0.13 ENSRNOT00000089536
cAMP responsive element modulator
chr10_+_55013703 0.13 ENSRNOT00000032785
phosphoinositide-3-kinase, regulatory subunit 5
chr1_-_226292480 0.13 ENSRNOT00000039133
myelin regulatory factor
chr3_+_56966654 0.13 ENSRNOT00000088097
golgi reassembly stacking protein 2
chr10_+_105861743 0.13 ENSRNOT00000064410
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chrX_-_131343853 0.13 ENSRNOT00000038653
DDB1 and CUL4 associated factor 12-like 1
chr5_-_61077627 0.13 ENSRNOT00000015338
SH2 domain containing adaptor protein B
chr7_-_2909144 0.12 ENSRNOT00000082518
ENSRNOT00000089074
ENSRNOT00000085644
myosin light chain 6
chr19_+_37652969 0.12 ENSRNOT00000041970
capping protein regulator and myosin 1 linker 2
chr8_-_110813000 0.12 ENSRNOT00000010634
Eph receptor B1
chr12_-_46794797 0.12 ENSRNOT00000001518
ribosomal protein lateral stalk subunit P0
chr1_-_52962388 0.12 ENSRNOT00000033685
brachyury 2
chr6_+_136720582 0.12 ENSRNOT00000086868
kinesin family member 26A
chr3_+_160908769 0.12 ENSRNOT00000030054
Sys1 golgi trafficking protein
chr5_-_60658521 0.12 ENSRNOT00000092866
ENSRNOT00000093024
ENSRNOT00000016875
translocase of outer mitochondrial membrane 5
F-box protein 10
chr16_+_9563218 0.11 ENSRNOT00000035915
Rho GTPase activating protein 22
chr3_+_14588870 0.11 ENSRNOT00000071712
spermidine synthase-like
chr4_+_170958196 0.11 ENSRNOT00000007905
phosphodiesterase 6H
chr8_-_104912959 0.11 ENSRNOT00000017363
splA/ryanodine receptor domain and SOCS box containing 4
chr10_-_46332172 0.11 ENSRNOT00000004475
ras related dexamethasone induced 1
chr5_-_159602251 0.11 ENSRNOT00000011394
NECAP endocytosis associated 2
chr9_+_98505259 0.11 ENSRNOT00000051810
erythroferrone
chr15_+_31948035 0.11 ENSRNOT00000071627

chr15_+_2631529 0.11 ENSRNOT00000018897
catechol-O-methyltransferase domain containing 1
chr10_+_13723405 0.11 ENSRNOT00000072789
ATP binding cassette subfamily A member 3
chr5_-_156141537 0.11 ENSRNOT00000019004
alkaline phosphatase, liver/bone/kidney
chr8_-_130491998 0.11 ENSRNOT00000064114
HIG1 hypoxia inducible domain family, member 1A
chr9_-_15306465 0.11 ENSRNOT00000019404
fibroblast growth factor receptor substrate 3
chr19_-_15733412 0.10 ENSRNOT00000014831
iroquois homeobox 6
chr4_+_155313671 0.10 ENSRNOT00000020812
microfibrillar associated protein 5
chr19_+_38397466 0.10 ENSRNOT00000034386
NIN1/PSMD8 binding protein 1 homolog
chr3_+_176093640 0.10 ENSRNOT00000086541
opioid growth factor receptor
chr6_+_136720266 0.10 ENSRNOT00000018278
kinesin family member 26A
chr5_+_169506138 0.10 ENSRNOT00000014904
ribosomal protein L22
chr19_-_10620671 0.10 ENSRNOT00000021842
C-C motif chemokine ligand 17
chr1_-_85517360 0.10 ENSRNOT00000026114
EP300 interacting inhibitor of differentiation 2
chr17_+_26785029 0.10 ENSRNOT00000022065
eukaryotic translation elongation factor 1 epsilon 1
chr2_+_238529074 0.10 ENSRNOT00000016195
pyrophosphatase (inorganic) 2
chr1_+_101213788 0.10 ENSRNOT00000090838
TEA domain transcription factor 2
chr10_-_14092289 0.10 ENSRNOT00000019624
NADH:ubiquinone oxidoreductase subunit B10
chr16_+_81204766 0.09 ENSRNOT00000042465
transmembrane protein 255B
chr5_+_104941066 0.09 ENSRNOT00000009225
Ras-related GTP binding A
chr15_+_12407524 0.09 ENSRNOT00000009249
proteasome 26S subunit, non-ATPase 6
chr3_+_168124673 0.09 ENSRNOT00000070809
prefoldin subunit 4
chr13_-_50509916 0.09 ENSRNOT00000076747
renin
chr20_+_7818289 0.09 ENSRNOT00000042539
peroxisome proliferator-activated receptor delta
chr3_+_72191533 0.09 ENSRNOT00000044319
ubiquitin-conjugating enzyme E2L 6
chr11_+_36851038 0.09 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr13_+_79886832 0.09 ENSRNOT00000077069
ENSRNOT00000035558
ENSRNOT00000076417
phosphatidylinositol glycan anchor biosynthesis, class C
chr11_-_72109964 0.09 ENSRNOT00000058917

chr6_-_128989812 0.09 ENSRNOT00000085943
ankyrin repeat and SOCS box protein 2-like
chr5_-_2632030 0.09 ENSRNOT00000009096
retinol dehydrogenase 10
chr19_-_37952501 0.09 ENSRNOT00000026809
dipeptidase 3
chrX_-_105390580 0.09 ENSRNOT00000077547
Bruton tyrosine kinase
chr5_-_107857320 0.09 ENSRNOT00000008898
cyclin-dependent kinase inhibitor 2B
chr11_+_86516390 0.09 ENSRNOT00000041168
glycoprotein Ib platelet beta subunit
chr10_-_97582188 0.09 ENSRNOT00000005076
regulator of G-protein signaling 9
chr19_-_26243223 0.09 ENSRNOT00000037766
zinc finger protein 791
chr10_-_57618527 0.09 ENSRNOT00000037517
complement C1q binding protein
chr11_+_73738433 0.08 ENSRNOT00000002353
transmembrane protein 44
chr3_+_164274710 0.08 ENSRNOT00000012939
snail family transcriptional repressor 1
chr1_-_216920625 0.08 ENSRNOT00000028119
oxysterol binding protein-like 5
chr14_+_86029335 0.08 ENSRNOT00000017375
drebrin-like
chr1_+_173532803 0.08 ENSRNOT00000021017
eukaryotic translation initiation factor 3, subunit F
chr1_-_101131012 0.08 ENSRNOT00000082283
ENSRNOT00000093498
ENSRNOT00000093559
fms-related tyrosine kinase 3 ligand
ribosomal protein L13A
chr12_+_13299859 0.08 ENSRNOT00000039191
similar to Protein C7orf26 homolog
chr8_+_128806129 0.08 ENSRNOT00000025225
ribosomal protein SA
chr2_+_207271853 0.08 ENSRNOT00000085355
ENSRNOT00000017254
ras homolog family member C
chr10_-_70241254 0.08 ENSRNOT00000038376
RAD51 paralog D
chr2_+_198772937 0.08 ENSRNOT00000028812
integrin subunit alpha 10
chr14_+_83752393 0.08 ENSRNOT00000081123
selenoprotein M
chr13_+_96195836 0.08 ENSRNOT00000042547
similar to basic transcription factor 3
chr1_+_221773254 0.08 ENSRNOT00000028646
RAS guanyl releasing protein 2
chr4_+_117589591 0.08 ENSRNOT00000078239
EKC/KEOPS complex subunit Tprkb
chr10_-_19715832 0.08 ENSRNOT00000040278
similar to ribosomal protein S10
chr1_-_190598122 0.08 ENSRNOT00000044384
PDZ domain containing 9
chr1_-_89483988 0.08 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7
chr1_-_8878136 0.08 ENSRNOT00000064836
ENSRNOT00000075850
vesicle trafficking 1
chrX_+_70322755 0.08 ENSRNOT00000057900
immunoglobulin (CD79A) binding protein 1
chr14_+_10581136 0.08 ENSRNOT00000002987
coenzyme Q2, polyprenyltransferase
chr7_-_11699436 0.08 ENSRNOT00000049221
ENSRNOT00000066037
transmembrane protease, serine 9
chr5_+_173274774 0.08 ENSRNOT00000025952
cyclin L2
chr1_-_198298076 0.08 ENSRNOT00000027033
INO80 complex subunit E
chr13_-_90832138 0.08 ENSRNOT00000010930
immunoglobulin superfamily, member 9
chr18_-_37776453 0.07 ENSRNOT00000087876
dihydropyrimidinase-like 3
chr1_-_52354175 0.07 ENSRNOT00000015010
hypothetical protein LOC681210
chr1_-_1116926 0.07 ENSRNOT00000062027
retinoic acid early transcript 1L
chr7_-_12793711 0.07 ENSRNOT00000013762
paralemmin
chr1_+_221792221 0.07 ENSRNOT00000054828
neurexin 2
chr10_-_109757550 0.07 ENSRNOT00000054957
Rho GDP dissociation inhibitor alpha
chr18_-_27206777 0.07 ENSRNOT00000090569

chr1_+_220243473 0.07 ENSRNOT00000084650
ENSRNOT00000027091
mitochondrial ribosomal protein L11
chr3_+_146980923 0.07 ENSRNOT00000011654
NSFL1 cofactor
chr6_+_75429729 0.07 ENSRNOT00000043250
ribosomal protein S10-like 1
chr2_-_198719202 0.07 ENSRNOT00000028801
RNA polymerase III subunit G like
chr1_-_101131413 0.07 ENSRNOT00000093729
fms-related tyrosine kinase 3 ligand
chr9_+_100076958 0.07 ENSRNOT00000084297
dual specificity phosphatase 28
chrX_-_1741701 0.07 ENSRNOT00000031115
ubiquitin-like modifier activating enzyme 1
chr12_+_22165486 0.07 ENSRNOT00000001890
motile sperm domain containing 3
chr13_-_68360664 0.07 ENSRNOT00000030971
hemicentin 1
chr8_-_62424303 0.07 ENSRNOT00000091223
c-src tyrosine kinase
chr11_-_72157522 0.07 ENSRNOT00000002373
melanotransferrin
chr13_-_112005052 0.07 ENSRNOT00000007879
G0/G1switch 2
chr17_+_9631925 0.07 ENSRNOT00000018114
DEAD-box helicase 41
chr2_+_248249468 0.06 ENSRNOT00000022648
guanylate binding protein 4
chr7_+_12006710 0.06 ENSRNOT00000045421
Kruppel-like factor 16
chr14_+_78213635 0.06 ENSRNOT00000010541
EvC ciliary complex subunit 1
chr12_-_30566032 0.06 ENSRNOT00000093378
glioblastoma amplified sequence
chr9_+_10941613 0.06 ENSRNOT00000070794
semaphorin 6B
chr20_-_32416044 0.06 ENSRNOT00000067004
cell division cycle and apoptosis regulator 1
chr19_+_60104804 0.06 ENSRNOT00000078559
par-3 family cell polarity regulator
chr1_-_101426852 0.06 ENSRNOT00000028217
RuvB-like AAA ATPase 2
chr10_+_103703404 0.06 ENSRNOT00000086469
RAB37, member RAS oncogene family
chrX_-_115496045 0.06 ENSRNOT00000051134
ribosomal protein S26-like
chr2_-_188471988 0.06 ENSRNOT00000027785
hyperpolarization-activated cyclic nucleotide-gated potassium channel 3
chr1_+_78818404 0.06 ENSRNOT00000090417
G protein subunit gamma 8
chr20_+_7908304 0.06 ENSRNOT00000000603
ribosomal protein L10A
chr2_-_44907030 0.06 ENSRNOT00000013979
glutathione peroxidase 8
chr10_+_56260514 0.06 ENSRNOT00000016177
SRY box 15
chr2_-_185303610 0.06 ENSRNOT00000093479
ENSRNOT00000046286
protease, serine 48
chr15_+_31462806 0.06 ENSRNOT00000072946

chr9_+_40975836 0.06 ENSRNOT00000084470
protein tyrosine phosphatase, non-receptor type 18
chr20_-_14282873 0.06 ENSRNOT00000001759
adenosine A2a receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of Rad21_Smc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035711 granuloma formation(GO:0002432) T-helper 1 cell activation(GO:0035711)
0.1 0.3 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 0.3 GO:1903544 positive regulation of bicellular tight junction assembly(GO:1903348) response to butyrate(GO:1903544)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.2 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.2 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.0 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.0 0.2 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.0 GO:0002458 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465)
0.0 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.2 GO:0002503 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
0.0 0.1 GO:0071226 positive regulation of type I hypersensitivity(GO:0001812) peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.1 GO:0002018 angiotensin maturation(GO:0002003) renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.0 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290) eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0047429 deoxyribonucleotide binding(GO:0032552) nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions