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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Prrx1_Isx_Prrxl1
Z-value: 0.48
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Transcription factors associated with Prrx1_Isx_Prrxl1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Prrx1 | rn6_v1_chr13_-_81214494_81214546 | 0.55 | 3.4e-01 | Click! |
| Drgx | rn6_v1_chr16_+_8823872_8823872 | 0.35 | 5.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_47677720 Show fit | 0.32 |
ENSRNOT00000065340
|
T-box, brain, 1 |
|
| chr14_+_69800156 Show fit | 0.29 |
ENSRNOT00000072746
|
ligand dependent nuclear receptor corepressor-like |
|
| chr8_-_102149912 Show fit | 0.28 |
ENSRNOT00000011263
|
similar to Ab2-095 |
|
| chr3_+_155160481 Show fit | 0.26 |
ENSRNOT00000021133
|
protein phosphatase 1, regulatory subunit 16B |
|
| chr4_+_51614676 Show fit | 0.23 |
ENSRNOT00000060494
|
ankyrin repeat and SOCS box containing 15 |
|
| chr18_-_32207749 Show fit | 0.23 |
ENSRNOT00000090882
ENSRNOT00000018843 |
Rho GTPase activating protein 26 |
|
| chr2_+_198303168 Show fit | 0.22 |
ENSRNOT00000056262
|
myotubularin related protein 11 |
|
| chr10_+_56381813 Show fit | 0.22 |
ENSRNOT00000019687
|
zinc finger and BTB domain containing 4 |
|
| chr1_-_167911961 Show fit | 0.21 |
ENSRNOT00000025097
|
olfactory receptor 59 |
|
| chr13_-_55561726 Show fit | 0.21 |
ENSRNOT00000000817
ENSRNOT00000090162 |
NIMA-related kinase 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Prrx1_Isx_Prrxl1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.0 | 0.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.1 | 0.2 | GO:1900135 | positive regulation of renin secretion into blood stream(GO:1900135) |
| 0.1 | 0.2 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.0 | 0.2 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.0 | 0.2 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.0 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.2 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.0 | 0.2 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 0.2 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.0 | 0.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 0.1 | GO:0031230 | intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203) |
| 0.0 | 0.1 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.0 | GO:1990421 | subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.1 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 0.1 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 0.1 | GO:0001642 | group III metabotropic glutamate receptor activity(GO:0001642) |
| 0.0 | 0.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.0 | 0.1 | GO:0002134 | UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.0 | 0.1 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.1 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.1 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |