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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Prop1
Z-value: 0.45
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Transcription factors associated with Prop1
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_+_91054974 Show fit | 0.31 |
ENSRNOT00000091089
|
C-reactive protein |
|
| chr3_+_177397892 Show fit | 0.23 |
ENSRNOT00000078261
|
|
|
| chrM_+_9870 Show fit | 0.21 |
ENSRNOT00000044582
|
mitochondrially encoded NADH 4L dehydrogenase |
|
| chr4_+_51614676 Show fit | 0.16 |
ENSRNOT00000060494
|
ankyrin repeat and SOCS box containing 15 |
|
| chr2_-_149444548 Show fit | 0.15 |
ENSRNOT00000018600
|
purinergic receptor P2Y12 |
|
| chr5_+_6373583 Show fit | 0.14 |
ENSRNOT00000084749
|
|
|
| chr2_+_148262110 Show fit | 0.14 |
ENSRNOT00000046641
|
|
|
| chr1_-_163554839 Show fit | 0.14 |
ENSRNOT00000081509
|
EMSY BRCA2-interacting transcriptional repressor |
|
| chr15_+_62406873 Show fit | 0.12 |
ENSRNOT00000047572
|
olfactomedin 4 |
|
| chr1_+_255040426 Show fit | 0.12 |
ENSRNOT00000092151
|
polycomb group ring finger 5 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Prop1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 0.2 | GO:0007208 | phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) |
| 0.1 | 0.2 | GO:1904124 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.0 | 0.1 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.0 | 0.1 | GO:1900135 | positive regulation of renin secretion into blood stream(GO:1900135) |
| 0.0 | 0.1 | GO:0072695 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.0 | 0.1 | GO:0006480 | N-terminal protein amino acid methylation(GO:0006480) |
| 0.0 | 0.1 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.1 | GO:0048880 | medulla oblongata development(GO:0021550) sensory system development(GO:0048880) |
| 0.0 | 0.1 | GO:0071245 | cellular response to carbon monoxide(GO:0071245) cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 0.1 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.0 | 0.1 | GO:1990005 | granular vesicle(GO:1990005) |
| 0.0 | 0.1 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0071886 | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886) |
| 0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.1 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 0.0 | 0.1 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 0.0 | 0.1 | GO:0002134 | UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.0 | 0.1 | GO:0045174 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.1 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.1 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.1 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |