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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pparg_Rxrg

Z-value: 1.16

Motif logo

Transcription factors associated with Pparg_Rxrg

Gene Symbol Gene ID Gene Info
ENSRNOG00000008839 peroxisome proliferator-activated receptor gamma
ENSRNOG00000004537 retinoid X receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxrgrn6_v1_chr13_+_85818427_85818473-0.612.8e-01Click!
Ppargrn6_v1_chr4_+_147333056_1473330560.395.2e-01Click!

Activity profile of Pparg_Rxrg motif

Sorted Z-values of Pparg_Rxrg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 3.22 ENSRNOT00000001313
Purkinje cell protein 2
chr3_-_66417741 1.76 ENSRNOT00000007662
neuronal differentiation 1
chr10_+_84167331 0.90 ENSRNOT00000010965
homeo box B4
chr1_-_226049929 0.88 ENSRNOT00000007320
bestrophin 1
chr10_-_15603649 0.75 ENSRNOT00000051483
hemoglobin alpha, adult chain 2
chr10_+_59533480 0.69 ENSRNOT00000087723
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr7_-_119441487 0.62 ENSRNOT00000067635
parvalbumin
chr5_-_172809353 0.61 ENSRNOT00000022246
gamma-aminobutyric acid type A receptor delta subunit
chr19_+_41482728 0.58 ENSRNOT00000022943
calbindin 2
chr3_+_123106694 0.56 ENSRNOT00000028829
oxytocin/neurophysin 1 prepropeptide
chr3_+_149624712 0.53 ENSRNOT00000018581
BPI fold containing family A, member 1
chr7_-_143793774 0.52 ENSRNOT00000079678
cysteine sulfinic acid decarboxylase
chr1_-_166939541 0.50 ENSRNOT00000079675
folate receptor 1
chr12_-_18526250 0.49 ENSRNOT00000001791
acetylserotonin O-methyltransferase
chr10_+_56662561 0.49 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr6_+_43001948 0.48 ENSRNOT00000007374
hippocalcin-like 1
chr10_+_56662242 0.47 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr7_-_143793970 0.46 ENSRNOT00000016205
cysteine sulfinic acid decarboxylase
chr3_-_7498555 0.44 ENSRNOT00000017725
BarH-like homeobox 1
chr1_-_262013619 0.43 ENSRNOT00000021278
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chrX_-_40086870 0.43 ENSRNOT00000010027
small muscle protein, X-linked
chr6_+_123361864 0.42 ENSRNOT00000057577

chr5_-_152473868 0.41 ENSRNOT00000022130
family with sequence similarity 110, member D
chr3_+_161121697 0.41 ENSRNOT00000036020
WAP four-disulfide core domain 10A
chr7_+_144647587 0.40 ENSRNOT00000022398
homeo box C4
chr10_+_103396155 0.40 ENSRNOT00000086924
G protein-coupled receptor, class C, group 5, member C
chr16_-_20890949 0.39 ENSRNOT00000081977
homer scaffolding protein 3
chr2_-_225107283 0.39 ENSRNOT00000055711
solute carrier family 44, member 3
chr7_+_120153184 0.39 ENSRNOT00000013538
galectin 1
chr7_+_117951154 0.39 ENSRNOT00000060181
zinc finger protein 7
chr9_-_65957101 0.36 ENSRNOT00000014094
membrane palmitoylated protein 4
chr10_+_86399827 0.35 ENSRNOT00000009299
growth factor receptor bound protein 7
chr19_-_37250919 0.34 ENSRNOT00000021015
exocyst complex component 3-like 1
chr10_+_13230158 0.33 ENSRNOT00000075648
common salivary protein 1
chr12_-_48627297 0.32 ENSRNOT00000000890
iron-sulfur cluster assembly enzyme
chr5_-_156734541 0.32 ENSRNOT00000021036
cytidine deaminase-like
chr12_+_49565992 0.31 ENSRNOT00000071328
crystallin, beta B3
chr8_-_22974321 0.31 ENSRNOT00000017369
erythropoietin receptor
chr10_-_15311189 0.31 ENSRNOT00000027371
proline rich 35
chr20_-_3819200 0.31 ENSRNOT00000000542
ENSRNOT00000081486
hydroxysteroid (17-beta) dehydrogenase 8
chr20_+_13827660 0.30 ENSRNOT00000093131
D-dopachrome tautomerase
chr3_-_1584946 0.29 ENSRNOT00000031058
paired box 8
chr1_-_89488223 0.29 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr4_+_100407658 0.29 ENSRNOT00000018562
capping actin protein, gelsolin like
chrX_-_123662350 0.29 ENSRNOT00000092624
septin 6
chr10_+_103395511 0.29 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr14_+_83752393 0.29 ENSRNOT00000081123
selenoprotein M
chr1_-_190965115 0.29 ENSRNOT00000023483

chr3_+_153197644 0.29 ENSRNOT00000008386
TBC/LysM-associated domain containing 2
chr3_+_172195844 0.28 ENSRNOT00000034915
aminopeptidase-like 1
chr9_+_14529218 0.28 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr3_+_159887036 0.28 ENSRNOT00000031868
R3H domain containing-like
chr13_-_102721218 0.28 ENSRNOT00000005459
mitochondrial amidoxime reducing component 1
chr5_+_137257287 0.27 ENSRNOT00000037160
ELOVL fatty acid elongase 1
chr10_+_104437648 0.26 ENSRNOT00000035001

chr20_+_13662867 0.26 ENSRNOT00000032257
similar to Homo sapiens fetal lung specific expression unknown
chr3_+_154786215 0.25 ENSRNOT00000019787
lipopolysaccharide binding protein
chr12_-_21746236 0.25 ENSRNOT00000001869
TSC22 domain family protein 4-like
chr8_-_22785671 0.25 ENSRNOT00000045384
SPC24, NDC80 kinetochore complex component
chr18_+_63130542 0.25 ENSRNOT00000024947
tubulin, beta 6 class V
chr7_-_144960527 0.25 ENSRNOT00000086554
zinc finger protein 385A
chr7_-_70842405 0.24 ENSRNOT00000047449
neurexophilin 4
chr2_-_187401786 0.24 ENSRNOT00000025624
hyaluronan and proteoglycan link protein 2
chr8_+_70112925 0.24 ENSRNOT00000082401
multiple EGF-like-domains 11
chr8_-_60086403 0.24 ENSRNOT00000020544
electron transfer flavoprotein alpha subunit
chr2_-_187863503 0.24 ENSRNOT00000093036
ENSRNOT00000026705
ENSRNOT00000082174
lamin A/C
chr5_-_148392689 0.23 ENSRNOT00000018464
ENSRNOT00000080166
tubulointerstitial nephritis antigen-like 1
chr1_+_71434819 0.23 ENSRNOT00000059069
zinc finger protein 787
chr6_+_26051396 0.23 ENSRNOT00000006452
ribokinase
chr5_+_167288223 0.23 ENSRNOT00000081579
enolase 1
chrX_-_10218583 0.22 ENSRNOT00000013382
nyctalopin
chr8_-_68312909 0.22 ENSRNOT00000066106
similar to ENSANGP00000021391
chr2_+_61991742 0.21 ENSRNOT00000046715
LRRGT00154
chr9_+_80118029 0.21 ENSRNOT00000023068
insulin-like growth factor binding protein 2
chr14_+_46001849 0.21 ENSRNOT00000076611
RELT-like 1
chr10_+_71202456 0.21 ENSRNOT00000076893
HNF1 homeobox B
chr2_-_210116038 0.21 ENSRNOT00000074950
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr13_-_50535389 0.20 ENSRNOT00000076506
KiSS-1 metastasis-suppressor
chr7_+_3173287 0.20 ENSRNOT00000092037
PYM homolog 1, exon junction complex associated factor
chr3_+_8832740 0.20 ENSRNOT00000022552
phytanoyl-CoA dioxygenase domain containing 1
chr8_+_98755104 0.20 ENSRNOT00000056562
Zic family member 4
chr15_+_24159647 0.20 ENSRNOT00000082675
galectin 3
chr9_-_82477136 0.20 ENSRNOT00000026753
ENSRNOT00000089555
regulated endocrine-specific protein 18
chr3_+_81287242 0.19 ENSRNOT00000086530
peroxisomal biogenesis factor 16
chr1_-_89369960 0.19 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr3_-_46361092 0.19 ENSRNOT00000008987
CD302 molecule
chr14_-_18733391 0.19 ENSRNOT00000003745
C-X-C motif chemokine ligand 2
chr1_-_187779675 0.19 ENSRNOT00000024648
ADP-ribosylation factor like GTPase 6 interacting protein 1
chr3_+_1452644 0.19 ENSRNOT00000007949
interleukin 1 receptor antagonist
chr9_+_69953440 0.19 ENSRNOT00000034740
eukaryotic translation elongation factor 1 beta 2
chr2_-_154334356 0.19 ENSRNOT00000057724
phospholipase C, eta 1
chr5_+_154522119 0.19 ENSRNOT00000072618
E2F transcription factor 2
chr1_-_89543967 0.18 ENSRNOT00000079631
hepsin
chr10_-_44746549 0.18 ENSRNOT00000003841
family with sequence similarity 183, member B
chr10_+_94566928 0.18 ENSRNOT00000078446
proline rich 29
chr10_+_23661343 0.18 ENSRNOT00000047970
early B-cell factor 1
chr1_+_219833299 0.18 ENSRNOT00000087432
pyruvate carboxylase
chr13_-_89745835 0.18 ENSRNOT00000005352
kelch domain containing 9
chr17_+_42302540 0.18 ENSRNOT00000025389
geminin, DNA replication inhibitor
chr9_-_65951516 0.18 ENSRNOT00000038132
membrane palmitoylated protein 4
chr10_+_11146359 0.18 ENSRNOT00000006314
presequence translocase associated motor 16 homolog
chr5_+_129257429 0.18 ENSRNOT00000072396
tetratricopeptide repeat domain 39A
chr5_-_154438361 0.17 ENSRNOT00000085003

chr13_-_89306219 0.17 ENSRNOT00000004183
ENSRNOT00000079247
Fc receptor-like A
chr11_+_87204175 0.17 ENSRNOT00000000306
solute carrier family 25 member 1
chr11_+_65022100 0.17 ENSRNOT00000003934
nuclear receptor subfamily 1, group I, member 2
chr15_+_38341089 0.17 ENSRNOT00000015367
fibroblast growth factor 9
chr7_-_120490061 0.17 ENSRNOT00000016247
solute carrier family 16 member 8
chr10_-_19652898 0.17 ENSRNOT00000009648
spindle apparatus coiled-coil protein 1
chr19_+_37229120 0.17 ENSRNOT00000076335
heat shock transcription factor 4
chr18_+_3565166 0.16 ENSRNOT00000039377
RIO kinase 3
chr1_+_168964202 0.16 ENSRNOT00000089102
hemoglobin subunit beta-2-like
chr9_+_73493027 0.16 ENSRNOT00000074427
ENSRNOT00000089478
unc-80 homolog, NALCN activator
chr1_-_7480825 0.16 ENSRNOT00000048754
phosphatase and actin regulator 2
chr12_+_22274828 0.16 ENSRNOT00000001914
erythropoietin
chr8_-_108109801 0.16 ENSRNOT00000034277
SRY box 14
chr20_+_13778178 0.16 ENSRNOT00000058314
glutathione S-transferase, theta 4
chr7_-_11400805 0.16 ENSRNOT00000027634
death-associated protein kinase 3
chr6_-_26051229 0.16 ENSRNOT00000005855
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr1_+_163445527 0.16 ENSRNOT00000020520
leucine rich repeat containing 32
chr7_+_119626637 0.16 ENSRNOT00000000201
mercaptopyruvate sulfurtransferase
chr18_-_29340403 0.16 ENSRNOT00000025157
heparin-binding EGF-like growth factor
chr1_+_88955440 0.16 ENSRNOT00000091101
proline dehydrogenase 2
chr3_-_153454160 0.16 ENSRNOT00000010298
growth hormone releasing hormone
chr10_-_59743315 0.16 ENSRNOT00000093646
ER membrane protein complex subunit 6
chr3_+_14482388 0.15 ENSRNOT00000025857
gelsolin
chr1_+_78659435 0.15 ENSRNOT00000071271
carcinoembryonic antigen-related cell adhesion molecule 9
chr1_-_24191908 0.15 ENSRNOT00000061157
serum/glucocorticoid regulated kinase 1
chr13_-_44345735 0.15 ENSRNOT00000005006
transmembrane protein 163
chr7_-_34485034 0.15 ENSRNOT00000007351
small nuclear ribonucleoprotein polypeptide F
chr13_+_85580828 0.15 ENSRNOT00000005611
aldehyde dehydrogenase 9 family, member A1
chr5_+_137243094 0.15 ENSRNOT00000067237
mediator complex subunit 8
chr1_-_211956858 0.15 ENSRNOT00000054886
cilia and flagella associated protein 46
chr3_-_2938883 0.15 ENSRNOT00000084196
allergen Fel d 4-like
chr10_-_59743037 0.15 ENSRNOT00000026168
ER membrane protein complex subunit 6
chr5_+_70441123 0.14 ENSRNOT00000087517
fibronectin type III and SPRY domain containing 1-like
chr11_-_84931160 0.14 ENSRNOT00000071848
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr8_+_72741155 0.14 ENSRNOT00000090977
ribosomal protein S27-like
chr12_-_30566032 0.14 ENSRNOT00000093378
glioblastoma amplified sequence
chr1_+_213886775 0.14 ENSRNOT00000020864
plakophilin 3
chr2_+_200452624 0.14 ENSRNOT00000026121
3-hydroxy-3-methylglutaryl-CoA synthase 2
chr5_+_57947716 0.14 ENSRNOT00000067657
dynein, axonemal, intermediate chain 1
chr9_+_64095978 0.14 ENSRNOT00000021533
matrix AAA peptidase interacting protein 1
chr10_-_103848035 0.14 ENSRNOT00000029001
fatty acid desaturase 6
chr7_-_130405347 0.14 ENSRNOT00000013985
carnitine palmitoyltransferase 1B
chr7_-_116963281 0.14 ENSRNOT00000082058
ENSRNOT00000012306
tissue specific transplantation antigen P35B
chr8_+_48569328 0.14 ENSRNOT00000084030
coiled-coil domain containing 153
chr7_-_117369159 0.13 ENSRNOT00000016424
5-oxoprolinase (ATP-hydrolysing)
chr9_+_70310932 0.13 ENSRNOT00000088268
uncharacterized LOC103690541
chr6_-_60151420 0.13 ENSRNOT00000073910
interferon-related developmental regulator 1
chr1_-_224986291 0.13 ENSRNOT00000026284
TATA-box binding protein associated factor 6 like
chr4_-_176679815 0.13 ENSRNOT00000090122
glycogen synthase 2
chr4_+_115046693 0.13 ENSRNOT00000031583
bolA family member 3
chr7_+_141889444 0.13 ENSRNOT00000079011
activating transcription factor 1
chr6_+_136358057 0.13 ENSRNOT00000092741
kinesin light chain 1
chr1_-_222178725 0.13 ENSRNOT00000028697
estrogen related receptor, alpha
chr5_+_169364306 0.13 ENSRNOT00000014213
acyl-CoA thioesterase 7
chr14_+_11198896 0.13 ENSRNOT00000079767
heterogeneous nuclear ribonucleoprotein D-like
chr10_+_105073077 0.13 ENSRNOT00000083022
ENSRNOT00000086382
ENSRNOT00000087084
TEN1 CST complex subunit
chr16_+_81616604 0.13 ENSRNOT00000026392
ENSRNOT00000057740
ADP-ribosylhydrolase like 1
growth hormone regulated TBC protein 1
chr9_+_50526811 0.13 ENSRNOT00000036990
similar to RIKEN cDNA 1500015O10
chrX_+_136488691 0.13 ENSRNOT00000093432
Rho GTPase activating protein 36
chr1_+_72636959 0.13 ENSRNOT00000023489
interleukin 11
chr8_+_99894762 0.13 ENSRNOT00000081768
phospholipid scramblase 4
chr12_-_2661565 0.13 ENSRNOT00000064859
CD209f antigen
chr10_-_108196217 0.13 ENSRNOT00000075440
chromobox 4
chr17_-_32558180 0.13 ENSRNOT00000022681
serine (or cysteine) peptidase inhibitor, clade B, member 1b
chr5_+_59008933 0.13 ENSRNOT00000023060
carbonic anhydrase 9
chr3_-_165360292 0.13 ENSRNOT00000065615
nuclear factor of activated T-cells 2
chr5_+_137257637 0.13 ENSRNOT00000093001
ELOVL fatty acid elongase 1
chr19_+_24800072 0.13 ENSRNOT00000005470
prostaglandin E receptor 1
chr6_+_107460668 0.12 ENSRNOT00000013515
acyl-CoA thioesterase 2
chr10_-_45923829 0.12 ENSRNOT00000035285
olfactory receptor 1462
chr3_+_176691329 0.12 ENSRNOT00000017319
pancreatic progenitor cell differentiation and proliferation factor
chr1_-_91042230 0.12 ENSRNOT00000073107
DNA-directed RNA polymerase II subunit RPB9
chrX_-_113584459 0.12 ENSRNOT00000025923
potassium voltage-gated channel subfamily E regulatory subunit 5
chr4_-_145390447 0.12 ENSRNOT00000091965
ENSRNOT00000012136
cell death-inducing DFFA-like effector c
chr20_+_46667454 0.12 ENSRNOT00000065890
sestrin 1
chr9_-_50820290 0.12 ENSRNOT00000050748
uncharacterized LOC102548013
chr1_-_89360733 0.12 ENSRNOT00000028544
myelin-associated glycoprotein
chr4_-_181477281 0.12 ENSRNOT00000055463
MANSC domain containing 4
chr6_-_33738825 0.12 ENSRNOT00000039492
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr6_+_76174452 0.12 ENSRNOT00000084062
proteasome subunit alpha 6
chr2_-_148722263 0.12 ENSRNOT00000017868
stress-associated endoplasmic reticulum protein 1
chr6_+_51662224 0.12 ENSRNOT00000060006
coiled-coil domain containing 71-like
chr15_+_12569235 0.12 ENSRNOT00000083787
THO complex 7
chr7_+_124460358 0.12 ENSRNOT00000014089
translocator protein
chr2_+_188688719 0.12 ENSRNOT00000081189
DC-STAMP domain containing 2
chr4_-_170912629 0.12 ENSRNOT00000055691
endoplasmic reticulum protein 27
chr17_+_9282675 0.12 ENSRNOT00000051702
H2A histone family, member Y
chr5_-_136762986 0.12 ENSRNOT00000026852
artemin
chr10_+_47490153 0.11 ENSRNOT00000003182
aldehyde dehydrogenase 3 family, member A1
chr6_-_44361908 0.11 ENSRNOT00000009491
inhibitor of DNA binding 2, HLH protein
chr1_+_89008117 0.11 ENSRNOT00000028401
heat shock protein family B (small) member 6
chr18_-_81807627 0.11 ENSRNOT00000020376
translocase of inner mitochondrial membrane 21
chr3_+_61685619 0.11 ENSRNOT00000002140
homeo box D1
chr19_+_20147037 0.11 ENSRNOT00000020028
zinc finger protein 423
chr12_+_25561777 0.11 ENSRNOT00000002032
RCC1 like
chr10_-_90999506 0.11 ENSRNOT00000034401
glial fibrillary acidic protein
chr16_+_49462889 0.11 ENSRNOT00000039909
ankyrin repeat domain 37

Network of associatons between targets according to the STRING database.

First level regulatory network of Pparg_Rxrg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.4 1.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.3 1.0 GO:0042412 taurine biosynthetic process(GO:0042412)
0.2 0.6 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.2 0.6 GO:0030186 melatonin metabolic process(GO:0030186)
0.2 0.7 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 0.5 GO:0043133 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.2 0.5 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.2 0.2 GO:0051542 elastin biosynthetic process(GO:0051542)
0.1 0.4 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539)
0.1 0.4 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.1 0.3 GO:1904373 response to kainic acid(GO:1904373)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:0015920 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.1 0.9 GO:0015671 oxygen transport(GO:0015671)
0.1 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.5 GO:0035338 fatty acid elongation, monounsaturated fatty acid(GO:0034625) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.2 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.2 GO:0061017 regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) hepatoblast differentiation(GO:0061017)
0.1 0.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.2 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.2 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.2 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.2 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
0.0 0.1 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.0 0.1 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.0 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0015746 citrate transport(GO:0015746)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0033128 negative regulation of histone phosphorylation(GO:0033128) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0010625 positive regulation of Schwann cell proliferation(GO:0010625)
0.0 0.3 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0034696 response to prostaglandin F(GO:0034696) ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.0 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.2 GO:0035934 corticosterone secretion(GO:0035934)
0.0 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0046016 positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0046061 DNA protection(GO:0042262) dATP catabolic process(GO:0046061)
0.0 0.1 GO:0072249 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.0 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0006559 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0006554 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.0 0.0 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.1 GO:0003166 bundle of His development(GO:0003166) negative regulation of B cell differentiation(GO:0045578)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) cardiac vascular smooth muscle cell development(GO:0060948) positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
0.0 0.1 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598)
0.0 0.1 GO:0072656 response to vitamin B1(GO:0010266) positive regulation of necrotic cell death(GO:0010940) maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 0.0 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.0 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0032927 male sex determination(GO:0030238) positive regulation of activin receptor signaling pathway(GO:0032927) lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.0 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.0 GO:0060661 submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.0 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.3 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0009758 carbohydrate utilization(GO:0009758) fructose transport(GO:0015755)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0032819 positive regulation of natural killer cell proliferation(GO:0032819)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:0098705 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.0 GO:0060332 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0032173 septin collar(GO:0032173)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:1903349 omegasome membrane(GO:1903349) omegasome(GO:1990462)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0032398 MHC class Ib protein complex(GO:0032398)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.5 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 0.3 GO:0008940 nitrate reductase activity(GO:0008940)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.2 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.0 0.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 1.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.0 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004159 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0035375 zymogen binding(GO:0035375)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 1.1 GO:0038024 cargo receptor activity(GO:0038024)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.0 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.0 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0043176 amine binding(GO:0043176)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0019203 carbohydrate phosphatase activity(GO:0019203)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism