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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pou6f2_Pou4f2

Z-value: 0.29

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Transcription factors associated with Pou6f2_Pou4f2

Gene Symbol Gene ID Gene Info
ENSRNOG00000013237 POU domain, class 6, transcription factor 2
ENSRNOG00000012167 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou6f2rn6_v1_chr17_+_49322205_49322205-0.503.9e-01Click!
Pou4f2rn6_v1_chr19_+_33160180_33160180-0.207.5e-01Click!

Activity profile of Pou6f2_Pou4f2 motif

Sorted Z-values of Pou6f2_Pou4f2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 0.38 ENSRNOT00000001313
Purkinje cell protein 2
chr3_-_66417741 0.15 ENSRNOT00000007662
neuronal differentiation 1
chr2_+_122877286 0.15 ENSRNOT00000033080
arylsulfatase E
chr13_+_71107465 0.13 ENSRNOT00000003239
regulator of G-protein signaling 8
chr12_-_17186679 0.13 ENSRNOT00000001730
UNC homeobox
chr13_+_90723092 0.11 ENSRNOT00000010146
ATP-sensitive inward rectifier potassium channel 10
chr2_+_145174876 0.11 ENSRNOT00000040631
mab-21 like 1
chr19_-_58735173 0.08 ENSRNOT00000030077
pecanex homolog 2 (Drosophila)
chr12_-_45801842 0.08 ENSRNOT00000078837

chr1_+_40879747 0.07 ENSRNOT00000083702
A-kinase anchoring protein 12
chr10_+_55927223 0.06 ENSRNOT00000011523
potassium voltage-gated channel subfamily A regulatory beta subunit 3
chr2_-_32518643 0.06 ENSRNOT00000061032
microtubule associated serine/threonine kinase family member 4
chr2_+_207930796 0.06 ENSRNOT00000047827
potassium voltage-gated channel subfamily D member 3
chr5_+_139790395 0.06 ENSRNOT00000015033
regulating synaptic membrane exocytosis 3
chr16_+_23668595 0.05 ENSRNOT00000067886
pleckstrin and Sec7 domain containing 3
chr5_-_12526962 0.05 ENSRNOT00000092104
suppression of tumorigenicity 18
chr9_+_71915421 0.05 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr1_+_190666149 0.05 ENSRNOT00000089361
uncharacterized LOC102547219
chr4_+_68656928 0.04 ENSRNOT00000016232
taste receptor, type 2, member 108
chr2_+_2729829 0.04 ENSRNOT00000017068
spermatogenesis associated 9
chr6_+_73553210 0.04 ENSRNOT00000006562
A-kinase anchoring protein 6
chr9_+_73378057 0.04 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr6_-_44363915 0.04 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr6_-_67084234 0.04 ENSRNOT00000050372
NOVA alternative splicing regulator 1
chr15_-_109394905 0.04 ENSRNOT00000019602
ENSRNOT00000078424
transmembrane and tetratricopeptide repeat containing 4
chr3_+_48106099 0.04 ENSRNOT00000007218
solute carrier family 4 member 10
chr2_-_187786700 0.04 ENSRNOT00000092257
ENSRNOT00000092612
ENSRNOT00000068360
solute carrier family 25, member 44
chr18_+_30880020 0.04 ENSRNOT00000060468
protocadherin gamma subfamily B, 5
chr6_+_146784915 0.03 ENSRNOT00000008362
Sp8 transcription factor
chr18_-_31071371 0.03 ENSRNOT00000060432
diaphanous-related formin 1
chr1_+_141767940 0.03 ENSRNOT00000064034
zinc finger protein 710
chr12_+_10577068 0.03 ENSRNOT00000001282
ring finger protein 6
chr8_+_76754492 0.03 ENSRNOT00000085727
myosin IE
chr10_-_87286387 0.02 ENSRNOT00000044206
keratin 28
chr1_-_87825333 0.02 ENSRNOT00000072689
zinc finger protein 74
chr3_-_80933283 0.02 ENSRNOT00000007771
cAMP responsive element binding protein 3-like 1
chr8_+_103337472 0.02 ENSRNOT00000049729
progestin and adipoQ receptor family member 9
chr18_-_49937522 0.02 ENSRNOT00000033254
zinc finger protein 608
chrX_+_86126157 0.02 ENSRNOT00000006992
kelch-like family member 4
chr20_+_45458558 0.02 ENSRNOT00000000713
cyclin-dependent kinase 19
chr1_+_157920786 0.02 ENSRNOT00000014284
family with sequence similarity 181, member B
chr3_-_37803112 0.02 ENSRNOT00000059461
nebulin
chr8_-_132753145 0.02 ENSRNOT00000007467
ENSRNOT00000008172
similar to Solute carrier family 6 (neurotransmitter transporter), member 20
chrX_-_157200981 0.02 ENSRNOT00000087364

chr13_-_60567882 0.02 ENSRNOT00000004701
TROVE domain family, member 2
chr1_+_217345154 0.02 ENSRNOT00000092516
SH3 and multiple ankyrin repeat domains 2
chr5_-_109651730 0.01 ENSRNOT00000093032
ELAV like RNA binding protein 2
chr4_+_120672152 0.01 ENSRNOT00000077231
monoglyceride lipase
chr1_-_72311856 0.01 ENSRNOT00000021286
Epsin 1
chr3_-_57607683 0.01 ENSRNOT00000093222
ENSRNOT00000058524
methyltransferase like 8
chr18_-_26656879 0.01 ENSRNOT00000086729
erythrocyte membrane protein band 4.1 like 4A
chr8_-_39551700 0.01 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr10_-_29450644 0.01 ENSRNOT00000087937
adrenoceptor alpha 1B
chr4_+_181315444 0.01 ENSRNOT00000044147
PPFIA binding protein 1
chr15_+_4064706 0.01 ENSRNOT00000011956
synaptopodin 2-like
chr5_-_58198782 0.01 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr11_-_86303453 0.01 ENSRNOT00000071453
similar to CG15908-PA
chr19_-_50220455 0.01 ENSRNOT00000079760
short chain dehydrogenase/reductase family 42E, member 1
chr1_-_134871167 0.01 ENSRNOT00000076300
chromodomain helicase DNA binding protein 2
chr1_-_131460473 0.01 ENSRNOT00000084336
nuclear receptor subfamily 2, group F, member 2
chr2_-_205212681 0.01 ENSRNOT00000022575
thyroid stimulating hormone, beta
chr5_-_7941822 0.01 ENSRNOT00000079917
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_+_123260607 0.01 ENSRNOT00000066849
X-ray repair cross complementing 6
chr11_-_62067655 0.01 ENSRNOT00000093382
zinc finger and BTB domain containing 20
chr6_+_8284878 0.00 ENSRNOT00000009581
solute carrier family 3 member 1
chr7_+_41475163 0.00 ENSRNOT00000037844
dual specificity phosphatase 6
chr9_-_73799427 0.00 ENSRNOT00000067589
KAT8 regulatory NSL complex subunit 1-like
chr19_+_6046665 0.00 ENSRNOT00000084126
cadherin 8
chr10_-_87484935 0.00 ENSRNOT00000016752
keratin associated protein 3-1
chr1_+_261291870 0.00 ENSRNOT00000049914
4-hydroxy-2-oxoglutarate aldolase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases