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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pou4f3

Z-value: 0.32

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Transcription factors associated with Pou4f3

Gene Symbol Gene ID Gene Info
ENSRNOG00000018842 POU class 4 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou4f3rn6_v1_chr18_+_36713869_367138690.088.9e-01Click!

Activity profile of Pou4f3 motif

Sorted Z-values of Pou4f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_190370499 0.20 ENSRNOT00000084389

chr10_+_61685645 0.16 ENSRNOT00000003933
MAX network transcriptional repressor
chr2_+_127525285 0.13 ENSRNOT00000093247
inturned planar cell polarity protein
chr4_-_18396035 0.10 ENSRNOT00000034692
semaphorin 3A
chr17_-_79085076 0.09 ENSRNOT00000057851
family with sequence similarity 171, member A1
chr2_+_122877286 0.09 ENSRNOT00000033080
arylsulfatase E
chr19_+_24800072 0.08 ENSRNOT00000005470
prostaglandin E receptor 1
chr9_+_73378057 0.08 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr12_+_10577068 0.07 ENSRNOT00000001282
ring finger protein 6
chr18_+_30895831 0.07 ENSRNOT00000026985
protocadherin gamma subfamily A, 10
chr18_+_14757679 0.07 ENSRNOT00000071364
microtubule-associated protein, RP/EB family, member 2
chr4_-_66955732 0.06 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr5_-_161875362 0.06 ENSRNOT00000078237
PR/SET domain 2
chr19_+_14835822 0.05 ENSRNOT00000072804
RIKEN cDNA 1700007B14 gene
chr5_-_12199283 0.05 ENSRNOT00000007769
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr7_+_120923274 0.05 ENSRNOT00000049247
GTP binding protein 1
chr1_-_166912524 0.05 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr17_+_9596957 0.04 ENSRNOT00000017349
family with sequence similarity 193, member B
chr18_+_30869628 0.04 ENSRNOT00000060470
protocadherin gamma subfamily B, 4
chr18_+_30880020 0.04 ENSRNOT00000060468
protocadherin gamma subfamily B, 5
chr12_-_35979193 0.04 ENSRNOT00000071104
transmembrane protein 132B
chr17_-_4454701 0.04 ENSRNOT00000080750
ENSRNOT00000066950
death associated protein kinase 1
chr12_-_46493203 0.04 ENSRNOT00000057036
citron rho-interacting serine/threonine kinase
chr10_+_29606748 0.03 ENSRNOT00000080720

chr7_+_71157664 0.03 ENSRNOT00000005919
short chain dehydrogenase/reductase family 9C, member 7
chr8_-_126390801 0.03 ENSRNOT00000089732

chr14_-_19072677 0.03 ENSRNOT00000060548
similar to alpha-fetoprotein
chr16_-_20562399 0.03 ENSRNOT00000031692
leucine rich repeat containing 25
chr2_-_198706428 0.02 ENSRNOT00000085006
RNA polymerase III subunit G like
chr18_-_43945273 0.02 ENSRNOT00000088900
DTW domain containing 2
chr7_+_117456039 0.02 ENSRNOT00000051754
maestro heat-like repeat family member 1
chr8_+_118206698 0.02 ENSRNOT00000082607
ENSRNOT00000064140
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chrX_+_65040934 0.02 ENSRNOT00000044006
zinc finger CCCH-type containing 12B
chr6_+_42947334 0.02 ENSRNOT00000041376
similar to 60S ribosomal protein L35
chr8_-_57830504 0.02 ENSRNOT00000017683
DEAD-box helicase 10
chr4_-_180505916 0.02 ENSRNOT00000086465

chr3_+_55910177 0.02 ENSRNOT00000009969
kelch-like family member 41
chr7_-_140291620 0.02 ENSRNOT00000088323
adenylate cyclase 6
chr12_+_47218969 0.02 ENSRNOT00000081343
ENSRNOT00000038395
unc-119 lipid binding chaperone B
chr16_+_84465656 0.02 ENSRNOT00000043188
LRRGT00175
chr13_-_102857551 0.02 ENSRNOT00000080309
microtubule affinity regulating kinase 1
chr2_-_235257731 0.02 ENSRNOT00000078074
GAR1 ribonucleoprotein
chr19_+_6046665 0.01 ENSRNOT00000084126
cadherin 8
chr3_-_80933283 0.01 ENSRNOT00000007771
cAMP responsive element binding protein 3-like 1
chr10_+_103206014 0.01 ENSRNOT00000004081
tweety family member 2
chrX_-_76925195 0.01 ENSRNOT00000087977
ATRX, chromatin remodeler
chr1_-_164977633 0.01 ENSRNOT00000029629
ring finger protein 169
chr18_+_17043903 0.01 ENSRNOT00000068139
formin homology 2 domain containing 3
chr6_+_123034304 0.01 ENSRNOT00000078938
candidate plasticity gene 1
chr3_-_21904133 0.01 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr9_+_52687868 0.00 ENSRNOT00000083864
WD repeat domain 75
chr6_-_61405195 0.00 ENSRNOT00000008655
leucine rich repeat neuronal 3
chr10_-_89088993 0.00 ENSRNOT00000027458
C-C motif chemokine receptor 10
chr1_+_174702373 0.00 ENSRNOT00000013733
zinc finger protein 143
chr17_-_76281660 0.00 ENSRNOT00000058070
UPF2 regulator of nonsense transcripts homolog (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou4f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903375 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) facioacoustic ganglion development(GO:1903375)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors