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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Pou4f1_Pou6f1
Z-value: 0.67
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Transcription factors associated with Pou4f1_Pou6f1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou4f1 | rn6_v1_chr15_-_88622413_88622413 | -0.75 | 1.5e-01 | Click! |
| Pou6f1 | rn6_v1_chr7_-_142210738_142210738 | 0.20 | 7.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_41467064 Show fit | 0.39 |
ENSRNOT00000073231
|
|
|
| chr14_+_71533063 Show fit | 0.28 |
ENSRNOT00000004231
|
prominin 1 |
|
| chr14_-_55081551 Show fit | 0.24 |
ENSRNOT00000049245
|
protocadherin 7 |
|
| chr2_+_180012414 Show fit | 0.23 |
ENSRNOT00000082273
|
platelet derived growth factor C |
|
| chr5_+_25253010 Show fit | 0.22 |
ENSRNOT00000061333
|
RNA binding motif protein 12B |
|
| chr5_+_27326762 Show fit | 0.22 |
ENSRNOT00000066191
|
RUNX1 translocation partner 1 |
|
| chr8_-_123829749 Show fit | 0.21 |
ENSRNOT00000090467
|
|
|
| chr5_+_25725683 Show fit | 0.21 |
ENSRNOT00000087602
|
similar to swan |
|
| chr18_-_70924708 Show fit | 0.21 |
ENSRNOT00000025257
|
lipase G, endothelial type |
|
| chr4_+_22859622 Show fit | 0.20 |
ENSRNOT00000073501
ENSRNOT00000068410 |
ADAM metallopeptidase domain 22 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Pou4f1_Pou6f1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 0.1 | 0.2 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986) |
| 0.0 | 0.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.0 | 0.2 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.0 | 0.2 | GO:0048563 | post-embryonic organ morphogenesis(GO:0048563) |
| 0.0 | 0.1 | GO:2000078 | glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.0 | 0.1 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
| 0.0 | 0.1 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.0 | 0.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.0 | 0.1 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0071914 | prominosome(GO:0071914) |
| 0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 0.1 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 0.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.0 | 0.1 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.0 | 0.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.1 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 0.1 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.0 | 0.0 | GO:0032398 | MHC class Ib protein complex(GO:0032398) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.2 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.0 | 0.1 | GO:0015563 | thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563) |
| 0.0 | 0.1 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.0 | 0.1 | GO:0001605 | adrenomedullin receptor activity(GO:0001605) |
| 0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.0 | 0.1 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 0.1 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 0.1 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |