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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pou3f4

Z-value: 0.46

Motif logo

Transcription factors associated with Pou3f4

Gene Symbol Gene ID Gene Info
ENSRNOG00000002784 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f4rn6_v1_chrX_+_82143789_821437890.856.7e-02Click!

Activity profile of Pou3f4 motif

Sorted Z-values of Pou3f4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_124929025 0.16 ENSRNOT00000015447
EF-hand calcium binding domain 6
chr6_+_106052212 0.15 ENSRNOT00000010626
signal-induced proliferation-associated 1 like 1
chr2_-_104461863 0.14 ENSRNOT00000016953
corticotropin releasing hormone
chr5_-_153840178 0.13 ENSRNOT00000025075
NIPA-like domain containing 3
chr6_+_29518416 0.12 ENSRNOT00000078660

chr1_+_151439409 0.11 ENSRNOT00000022060
ENSRNOT00000050639
glutamate metabotropic receptor 5
chr7_-_93502571 0.11 ENSRNOT00000077033
ENSRNOT00000076080
sterile alpha motif domain containing 12
chr7_+_120923274 0.11 ENSRNOT00000049247
GTP binding protein 1
chr16_-_81880502 0.11 ENSRNOT00000079096
MCF.2 cell line derived transforming sequence-like
chr2_+_22909569 0.11 ENSRNOT00000073871
homer scaffolding protein 1
chr7_-_120518653 0.11 ENSRNOT00000016362
BAI1-associated protein 2-like 2
chr14_-_55081551 0.11 ENSRNOT00000049245
protocadherin 7
chr3_+_162357356 0.10 ENSRNOT00000030119
EYA transcriptional coactivator and phosphatase 2
chr5_-_161875362 0.10 ENSRNOT00000078237
PR/SET domain 2
chr3_+_8928534 0.10 ENSRNOT00000088509
ENSRNOT00000065300
mitoguardin 2
chr1_+_217151166 0.10 ENSRNOT00000071484
SH3 and multiple ankyrin repeat domains 2
chr10_-_67285617 0.10 ENSRNOT00000019044
UTP6 small subunit processome component
chr1_+_167051209 0.10 ENSRNOT00000055249
nuclear mitotic apparatus protein 1
chr3_-_107760550 0.09 ENSRNOT00000077091
ENSRNOT00000051638
Meis homeobox 2
chr9_+_119517101 0.09 ENSRNOT00000020476
lipin 2
chr11_-_90406797 0.09 ENSRNOT00000073049
snail family transcriptional repressor 2
chr3_+_72540538 0.09 ENSRNOT00000012379
apelin receptor
chr1_-_49844547 0.09 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr11_+_82194657 0.09 ENSRNOT00000002445
ets variant 5
chr7_+_121408829 0.09 ENSRNOT00000023434
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr6_+_44230985 0.09 ENSRNOT00000005858
kinase D-interacting substrate 220
chr1_+_156552328 0.09 ENSRNOT00000055401
discs large MAGUK scaffold protein 2
chr9_+_2190915 0.08 ENSRNOT00000077417
SATB homeobox 1
chr16_-_9658484 0.08 ENSRNOT00000065216
mitogen-activated protein kinase 8
chr1_-_88558696 0.08 ENSRNOT00000038642

chr7_+_133400485 0.08 ENSRNOT00000006219
contactin 1
chr5_+_116420690 0.08 ENSRNOT00000087089
nuclear factor I/A
chr10_+_54155876 0.08 ENSRNOT00000072855
growth arrest specific 7
chr20_-_31598118 0.07 ENSRNOT00000046537
collagen type XIII alpha 1 chain
chr10_+_71536533 0.07 ENSRNOT00000088138
acetyl-CoA carboxylase alpha
chr3_-_94418711 0.07 ENSRNOT00000089554
homeodomain interacting protein kinase 3
chrX_+_88298266 0.07 ENSRNOT00000041508

chr5_+_27326762 0.07 ENSRNOT00000066191
RUNX1 translocation partner 1
chr18_-_70924708 0.07 ENSRNOT00000025257
lipase G, endothelial type
chr5_+_145257714 0.06 ENSRNOT00000019214
DLG associated protein 3
chr1_+_65781547 0.06 ENSRNOT00000026204
zinc finger protein 329
chr17_-_43675934 0.06 ENSRNOT00000081345
histone cluster 1 H1 family member t
chr2_-_147693082 0.06 ENSRNOT00000022507
WW domain containing transcription regulator 1
chr15_-_55424024 0.06 ENSRNOT00000077733
nudix hydrolase 15
chr6_+_123034304 0.06 ENSRNOT00000078938
candidate plasticity gene 1
chr1_-_6970040 0.05 ENSRNOT00000016273
utrophin
chr18_+_30527705 0.05 ENSRNOT00000027168
protocadherin beta 14
chr8_-_63291966 0.05 ENSRNOT00000077762

chr8_+_82043403 0.05 ENSRNOT00000091789
myosin VA
chr18_+_30398113 0.05 ENSRNOT00000027206
protocadherin beta 5
chr1_+_236031988 0.05 ENSRNOT00000016164
proprotein convertase subtilisin/kexin type 5
chr11_+_20474483 0.05 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr3_-_150960030 0.05 ENSRNOT00000024714
nuclear receptor coactivator 6
chr7_+_28956512 0.05 ENSRNOT00000006946
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr5_-_12199283 0.05 ENSRNOT00000007769
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr5_-_57947183 0.05 ENSRNOT00000060642
family with sequence similarity 219, member A
chr12_-_22417980 0.05 ENSRNOT00000072208
EPH receptor B4
chrX_+_78042859 0.04 ENSRNOT00000003286
lysophosphatidic acid receptor 4
chr13_-_83425641 0.04 ENSRNOT00000063870
T-box 19
chr12_-_9607168 0.04 ENSRNOT00000001260
GS homeobox 1
chr15_+_12827707 0.04 ENSRNOT00000012452
Fez family zinc finger 2
chr11_+_42259761 0.04 ENSRNOT00000047310
Eph receptor A6
chrX_+_11648989 0.04 ENSRNOT00000041003
BCL6 co-repressor
chr16_+_32457521 0.04 ENSRNOT00000083579
chloride voltage-gated channel 3
chr2_+_12516702 0.04 ENSRNOT00000050072
transmembrane protein 161B
chr6_-_135251073 0.04 ENSRNOT00000088986
MOK protein kinase
chr1_+_127604197 0.04 ENSRNOT00000018463
lines homolog 1
chr2_+_41467064 0.04 ENSRNOT00000073231

chr1_-_166988062 0.04 ENSRNOT00000039564
leucine rich transmembrane and O-methyltransferase domain containing
chr2_+_182723854 0.04 ENSRNOT00000012658
secreted frizzled-related protein 2
chr17_+_26478315 0.03 ENSRNOT00000021669
solute carrier family 35 member B3
chr4_-_135069970 0.03 ENSRNOT00000008221
contactin 3
chr11_+_31640407 0.03 ENSRNOT00000029985
ENSRNOT00000091472
interferon alpha and beta receptor subunit 1
chr5_-_16799776 0.03 ENSRNOT00000011721
PLAG1 zinc finger
chr4_+_157125998 0.03 ENSRNOT00000078349
complement C1r
chr5_+_63870432 0.03 ENSRNOT00000007641
syntaxin 17
chr12_-_29743705 0.03 ENSRNOT00000001185
calneuron 1
chr1_-_251387002 0.03 ENSRNOT00000092063
ATPase family, AAA domain containing 1
chr7_-_140506925 0.03 ENSRNOT00000083354
lysine methyltransferase 2D
chr2_+_72006099 0.03 ENSRNOT00000034044
cadherin 12
chr9_-_81772851 0.02 ENSRNOT00000032719
ubiquitin specific peptidase 37
chr5_-_58198782 0.02 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr7_-_13108630 0.02 ENSRNOT00000087038
ENSRNOT00000080491
gonadotropin inducible ovarian transcription factor 1
chr2_-_2779109 0.02 ENSRNOT00000017098
Rieske (Fe-S) domain containing
chr10_-_88842233 0.02 ENSRNOT00000026760
signal transducer and activator of transcription 3
chr6_+_102215603 0.02 ENSRNOT00000014257
pleckstrin homology, MyTH4 and FERM domain containing H1
chr12_+_21981755 0.02 ENSRNOT00000001871
7SK snRNA methylphosphate capping enzyme-like
chr9_+_19451630 0.02 ENSRNOT00000065048
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr1_+_174702373 0.02 ENSRNOT00000013733
zinc finger protein 143
chr1_+_61733805 0.02 ENSRNOT00000086029
similar to Zinc finger protein 208
chr19_+_25120128 0.02 ENSRNOT00000081243
sterile alpha motif domain containing 1
chr10_-_87300728 0.02 ENSRNOT00000036023
ENSRNOT00000081709
keratin 10
chr3_-_26056818 0.02 ENSRNOT00000044209
LDL receptor related protein 1B
chr18_-_36322320 0.02 ENSRNOT00000060260
glutaredoxin and cysteine rich domain containing 2
chr20_+_25990304 0.02 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr6_-_50941248 0.02 ENSRNOT00000084533
dihydrouridine synthase 4-like
chr6_-_18351536 0.01 ENSRNOT00000061588
crooked neck pre-mRNA splicing factor 1
chr17_+_1305016 0.01 ENSRNOT00000025965
ERCC excision repair 6 like 2
chr5_+_48313599 0.01 ENSRNOT00000081825
gamma-aminobutyric acid type A receptor rho 2 subunit
chr15_-_71779033 0.01 ENSRNOT00000017765
protocadherin 20
chr10_-_87335823 0.01 ENSRNOT00000079297
keratin 12
chr10_-_13446135 0.01 ENSRNOT00000084991
potassium channel tetramerization domain containing 5
chr14_+_114152472 0.01 ENSRNOT00000042965
reticulon 4
chr19_-_11669578 0.01 ENSRNOT00000026373
G protein subunit alpha o1
chr6_+_7900972 0.01 ENSRNOT00000006953
ENSRNOT00000068030
dynein cytoplasmic 2 light intermediate chain 1
chr5_+_126698582 0.01 ENSRNOT00000012427
CUB domain containing protein 2
chr16_+_9486832 0.00 ENSRNOT00000082208
Rho GTPase activating protein 22
chr5_-_156689415 0.00 ENSRNOT00000083474
PTEN induced putative kinase 1
chr11_-_62128044 0.00 ENSRNOT00000093141
zinc finger and BTB domain containing 20
chr16_-_48921242 0.00 ENSRNOT00000041596
centromere protein U
chr13_-_82295123 0.00 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr1_+_219329574 0.00 ENSRNOT00000071109
calcium binding protein 2
chr17_-_14679409 0.00 ENSRNOT00000020704
asporin
chr9_-_45558993 0.00 ENSRNOT00000087866
ENSRNOT00000017714
carbohydrate sulfotransferase 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) negative regulation of glucagon secretion(GO:0070093)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268) malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.0 GO:2000040 sclerotome development(GO:0061056) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.1 GO:0042262 dGTP catabolic process(GO:0006203) DNA protection(GO:0042262)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:2000523 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.1 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.0 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)