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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pou2f3

Z-value: 0.29

Motif logo

Transcription factors associated with Pou2f3

Gene Symbol Gene ID Gene Info
ENSRNOG00000009118 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou2f3rn6_v1_chr8_-_47494982_47494982-0.108.7e-01Click!

Activity profile of Pou2f3 motif

Sorted Z-values of Pou2f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_190370499 0.19 ENSRNOT00000084389

chr14_-_6679878 0.16 ENSRNOT00000075989
ENSRNOT00000067875
secreted phosphoprotein 1
chr2_+_122877286 0.15 ENSRNOT00000033080
arylsulfatase E
chr10_-_51576376 0.15 ENSRNOT00000004829
Rho GTPase activating protein 44
chr4_+_148139528 0.12 ENSRNOT00000092594
ENSRNOT00000015620
ENSRNOT00000092613
WASH complex subunit 2C
chr2_+_127525285 0.12 ENSRNOT00000093247
inturned planar cell polarity protein
chr1_+_27476375 0.11 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr16_+_35116440 0.10 ENSRNOT00000074353

chr4_-_11610518 0.10 ENSRNOT00000066643
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_153840178 0.10 ENSRNOT00000025075
NIPA-like domain containing 3
chr7_+_122433099 0.09 ENSRNOT00000055447
thymosin, beta 10
chr18_-_399242 0.09 ENSRNOT00000045926
coagulation factor VIII
chr1_+_8310577 0.09 ENSRNOT00000015131
human immunodeficiency virus type I enhancer binding protein 2
chr15_+_61673560 0.09 ENSRNOT00000093661
mitochondrial translation release factor 1
chr9_-_65736852 0.08 ENSRNOT00000087458
trafficking kinesin protein 2
chr12_+_52356832 0.08 ENSRNOT00000050252
fibrosin-like 1
chr8_-_32328819 0.07 ENSRNOT00000074457
ENSRNOT00000070818
amyloid beta precursor like protein 2
chr4_+_168615890 0.07 ENSRNOT00000009324
cAMP responsive element binding protein-like 2
chr3_-_148312791 0.07 ENSRNOT00000091419
Bcl2-like 1
chr4_-_40036563 0.07 ENSRNOT00000084531
transmembrane protein 168
chr8_-_63750531 0.07 ENSRNOT00000009496
neogenin 1
chr16_+_78539489 0.07 ENSRNOT00000057897
CUB and Sushi multiple domains 1
chr7_-_70552897 0.07 ENSRNOT00000080594
kinesin family member 5A
chr16_-_75340360 0.07 ENSRNOT00000018501
defensin alpha 5
chr4_+_87026530 0.07 ENSRNOT00000018425
AVL9 cell migration associated
chr9_-_17209220 0.06 ENSRNOT00000083764
GTP binding protein 2
chr5_-_161875362 0.06 ENSRNOT00000078237
PR/SET domain 2
chr6_+_7793735 0.06 ENSRNOT00000090724
ENSRNOT00000006832
pleckstrin homology, MyTH4 and FERM domain containing H2
chr14_-_28967980 0.06 ENSRNOT00000048175
adhesion G protein-coupled receptor L3
chr3_-_112876773 0.06 ENSRNOT00000015086
ubiquitin protein ligase E3 component n-recognin 1
chr8_+_61659445 0.06 ENSRNOT00000023831
protein tyrosine phosphatase, non-receptor type 9
chr3_-_148312420 0.06 ENSRNOT00000047416
ENSRNOT00000081272
Bcl2-like 1
chr16_-_75481115 0.06 ENSRNOT00000035128
defensin alpha 7
chr6_-_76535517 0.05 ENSRNOT00000083857
Ral GTPase activating protein catalytic alpha subunit 1
chr13_+_48455923 0.05 ENSRNOT00000009280
Rab7b, member RAS oncogene family
chr10_-_88712309 0.05 ENSRNOT00000081247
signal transducer and activator of transcription 5B
chr14_+_76866135 0.05 ENSRNOT00000037291
zinc finger protein 518B
chr18_+_29951094 0.05 ENSRNOT00000027402
protocadherin alpha-1-like
chr17_+_36690249 0.05 ENSRNOT00000089476
ENSRNOT00000082140
similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a)
chr11_+_73078982 0.05 ENSRNOT00000029549
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_-_275882444 0.05 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr16_-_48921242 0.05 ENSRNOT00000041596
centromere protein U
chr19_-_22194740 0.05 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr9_-_88816898 0.05 ENSRNOT00000083667
solute carrier family 19 member 3
chr10_-_85049331 0.05 ENSRNOT00000012538
T-box 21
chr2_+_122368265 0.05 ENSRNOT00000078321
ATPase phospholipid transporting 11B (putative)
chr1_+_240355149 0.05 ENSRNOT00000018521
transient receptor potential cation channel, subfamily M, member 3
chr7_-_59547174 0.04 ENSRNOT00000085836
CCR4-NOT transcription complex, subunit 2
chr8_+_82043403 0.04 ENSRNOT00000091789
myosin VA
chr3_-_138683318 0.04 ENSRNOT00000029701
double zinc ribbon and ankyrin repeat domains 1
chr1_+_80293566 0.04 ENSRNOT00000024246
ERCC excision repair 2, TFIIH core complex helicase subunit
chr11_+_66316606 0.04 ENSRNOT00000041715
syntaxin binding protein 5-like
chr15_-_39742103 0.04 ENSRNOT00000074587
ENSRNOT00000036781
ENSRNOT00000071919
SET domain, bifurcated 2
chr1_+_23409408 0.04 ENSRNOT00000022362
EYA transcriptional coactivator and phosphatase 4
chr17_-_89163113 0.04 ENSRNOT00000050445
ribosomal protein S19-like
chr19_-_34752695 0.04 ENSRNOT00000052018
nuclear receptor subfamily 3, group C, member 2
chr5_+_151436464 0.04 ENSRNOT00000012463
mitogen-activated protein kinase kinase kinase 6
chr3_+_79570625 0.04 ENSRNOT00000078278
ENSRNOT00000009687
formin binding protein 4
chr5_-_150653172 0.04 ENSRNOT00000072028
mediator complex subunit 18
chr5_-_128333805 0.04 ENSRNOT00000037523
zinc finger FYVE-type containing 9
chr1_+_217173199 0.04 ENSRNOT00000075078
SH3 and multiple ankyrin repeat domains 2
chr4_-_117111653 0.04 ENSRNOT00000057537
sideroflexin 5
chr4_+_155088317 0.04 ENSRNOT00000088728
mannose-6-phosphate receptor, cation dependent
chr1_-_90035522 0.04 ENSRNOT00000028672
ubiquitin-like modifier activating enzyme 2
chr1_+_274688580 0.03 ENSRNOT00000020580
SHOC2 leucine-rich repeat scaffold protein
chr5_+_119727839 0.03 ENSRNOT00000014354
cache domain containing 1
chr3_+_58164931 0.03 ENSRNOT00000002078
distal-less homeobox 1
chr1_-_164977633 0.03 ENSRNOT00000029629
ring finger protein 169
chr8_+_78872102 0.03 ENSRNOT00000090047
zinc finger protein 280D
chr10_+_74959285 0.03 ENSRNOT00000010296
ring finger protein 43
chr1_+_219403970 0.03 ENSRNOT00000029607
protein tyrosine phosphatase, receptor type, C-associated protein
chr7_-_125497691 0.03 ENSRNOT00000049445

chr8_-_63092009 0.03 ENSRNOT00000034300
lysyl oxidase-like 1
chr16_+_32457521 0.03 ENSRNOT00000083579
chloride voltage-gated channel 3
chr1_+_225015616 0.03 ENSRNOT00000026416
heterogeneous nuclear ribonucleoprotein U-like 2
chr5_+_156439633 0.03 ENSRNOT00000090232
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_67134827 0.03 ENSRNOT00000045214
vomeronasal 1 receptor 45
chr18_+_30869628 0.03 ENSRNOT00000060470
protocadherin gamma subfamily B, 4
chr1_+_81372650 0.03 ENSRNOT00000088829
zinc finger protein 428
chr3_+_172155496 0.03 ENSRNOT00000066279
syntaxin 16
chr6_-_128434183 0.03 ENSRNOT00000014405
dicer 1 ribonuclease III
chr10_-_62814520 0.03 ENSRNOT00000019410
slingshot protein phosphatase 2
chr17_+_84881414 0.03 ENSRNOT00000034157
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr14_+_7171613 0.03 ENSRNOT00000081600
kelch-like family member 8
chr3_-_150960030 0.03 ENSRNOT00000024714
nuclear receptor coactivator 6
chr9_+_10941613 0.03 ENSRNOT00000070794
semaphorin 6B
chr19_+_387374 0.03 ENSRNOT00000075433
uncharacterized LOC102547811
chr7_+_26522314 0.03 ENSRNOT00000011572
solute carrier family 41 member 2
chr14_-_34177455 0.03 ENSRNOT00000059814
ENSRNOT00000091230
exocyst complex component 1
chr7_+_120923274 0.03 ENSRNOT00000049247
GTP binding protein 1
chr12_-_41993957 0.03 ENSRNOT00000001891
RNA binding motif protein 19
chr6_+_101532518 0.03 ENSRNOT00000075054
gephyrin
chr14_+_34389991 0.03 ENSRNOT00000002953
phosducin-like 2
chr8_+_71547468 0.03 ENSRNOT00000042369
casein kinase 1, gamma 1
chr9_-_75528644 0.03 ENSRNOT00000019283
erb-b2 receptor tyrosine kinase 4
chr7_-_13751271 0.03 ENSRNOT00000009931
solute carrier family 1 member 6
chrX_+_88298266 0.03 ENSRNOT00000041508

chr17_+_35435079 0.03 ENSRNOT00000074800
exocyst complex component 2
chr5_+_116420690 0.03 ENSRNOT00000087089
nuclear factor I/A
chr10_-_110274768 0.03 ENSRNOT00000054931
secreted and transmembrane 1A
chrX_-_1952111 0.03 ENSRNOT00000061140
jade family PHD finger 3
chrX_-_75224268 0.03 ENSRNOT00000089809
ATP binding cassette subfamily B member 7
chr9_-_80167033 0.03 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr1_-_7443863 0.03 ENSRNOT00000088558
phosphatase and actin regulator 2
chr1_+_171797516 0.03 ENSRNOT00000088110
PPFIA binding protein 2
chr15_-_36798814 0.03 ENSRNOT00000065764
centromere protein J
chr3_+_148150698 0.02 ENSRNOT00000087075
ENSRNOT00000010251
histocompatibility minor 13
chr1_+_57692836 0.02 ENSRNOT00000083968
ENSRNOT00000019358
chromodomain helicase DNA binding protein 1
chr17_-_43821536 0.02 ENSRNOT00000072286
histone H4 variant H4-v.1
chr11_-_80981415 0.02 ENSRNOT00000002499
ENSRNOT00000002496
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr10_+_78111050 0.02 ENSRNOT00000079364
COX11 cytochrome c oxidase copper chaperone
chr7_+_73273985 0.02 ENSRNOT00000077730
POP1 homolog, ribonuclease P/MRP subunit
chr4_+_174692331 0.02 ENSRNOT00000011770
pleckstrin homology domain containing A5
chr8_+_103938520 0.02 ENSRNOT00000067835
glycerol kinase 5 (putative)
chr5_+_122390522 0.02 ENSRNOT00000064567
SH3-domain GRB2-like (endophilin) interacting protein 1
chr5_-_139921013 0.02 ENSRNOT00000079957
small ArfGAP2
chrX_-_45000363 0.02 ENSRNOT00000035538
claudin 34E
chr19_-_37916813 0.02 ENSRNOT00000026585
lecithin cholesterol acyltransferase
chr9_+_46657575 0.02 ENSRNOT00000083322
mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_147756553 0.02 ENSRNOT00000086549
ENSRNOT00000014733
intraflagellar transport 122
chr5_+_155934490 0.02 ENSRNOT00000077933
ubiquitin carboxyl-terminal hydrolase 48-like
chr8_-_8524643 0.02 ENSRNOT00000009418
contactin 5
chr10_+_76280933 0.02 ENSRNOT00000051823
similar to Tceb2 protein
chr4_+_40161285 0.02 ENSRNOT00000050722
hypothetical protein LOC500035
chr16_+_6806170 0.02 ENSRNOT00000084713
Scm-like with four mbt domains 1
chr4_-_72143748 0.02 ENSRNOT00000024428
TRPM8 channel-associated factor 1
chr3_-_11102515 0.02 ENSRNOT00000035580
family with sequence similarity 78, member A
chr4_+_155654911 0.02 ENSRNOT00000087883
forkhead box J2
chr2_-_140387505 0.02 ENSRNOT00000047635
E74-like factor 2
chr16_-_48692476 0.02 ENSRNOT00000013118
interferon regulatory factor 2
chr18_+_30474947 0.02 ENSRNOT00000027188
protocadherin beta 9
chr16_+_71242470 0.02 ENSRNOT00000030489
leucine zipper and EF-hand containing transmembrane protein 2
chr18_+_30424814 0.02 ENSRNOT00000073425
protocadherin beta 7
chr8_+_32452885 0.02 ENSRNOT00000010423
PR/SET domain 10
chr18_+_30509393 0.02 ENSRNOT00000043846
protocadherin beta 12
chr10_+_30169257 0.02 ENSRNOT00000006436
ring finger protein 145
chr17_+_43679411 0.02 ENSRNOT00000085865

chr9_+_52023295 0.02 ENSRNOT00000004956
collagen type III alpha 1 chain
chr11_+_42259761 0.02 ENSRNOT00000047310
Eph receptor A6
chr4_+_61924013 0.02 ENSRNOT00000090717
bisphosphoglycerate mutase
chr1_+_72399157 0.02 ENSRNOT00000022349
zinc finger protein 579
chr3_-_123997277 0.02 ENSRNOT00000058238
similar to Proteasome subunit beta type 3 (Proteasome theta chain)
chr5_-_164714145 0.02 ENSRNOT00000055680
mitofusin-2-like
chr11_-_88374679 0.02 ENSRNOT00000002524
topoisomerase (DNA) III beta
chr7_-_120380200 0.02 ENSRNOT00000014878
similar to RIKEN cDNA 1700088E04
chr7_+_133856101 0.02 ENSRNOT00000038686
PDZ domain containing RING finger 4
chr8_-_93390305 0.02 ENSRNOT00000056930
inhibitor of Bruton tyrosine kinase
chr6_+_29106141 0.02 ENSRNOT00000084560
ATPase family, AAA domain containing 2B
chr7_+_11295892 0.02 ENSRNOT00000089004
tight junction protein 3
chr5_+_74941802 0.02 ENSRNOT00000015576
A-kinase anchoring protein 2
chr2_+_2694480 0.02 ENSRNOT00000083565

chr2_+_193778042 0.02 ENSRNOT00000090212
trichohyalin
chrX_-_63182385 0.02 ENSRNOT00000076613
zinc finger protein X-linked
chr8_-_116993193 0.02 ENSRNOT00000026327
dystroglycan 1
chr16_+_3293599 0.01 ENSRNOT00000081999
ENSRNOT00000047118
ENSRNOT00000020427
ELKS/RAB6-interacting/CAST family member 2
chr14_+_33624390 0.01 ENSRNOT00000002907
aminoadipate-semialdehyde dehydrogenase
chr15_+_57340579 0.01 ENSRNOT00000015467
zinc finger CCCH type containing 13
chr4_-_78074906 0.01 ENSRNOT00000080654
zinc finger protein 467
chr1_+_188420461 0.01 ENSRNOT00000037870
centriolar coiled-coil protein 110
chr3_-_143192408 0.01 ENSRNOT00000006885
similar to cystatin E2
chr17_+_30556884 0.01 ENSRNOT00000080929
ENSRNOT00000022022
enoyl-CoA delta isomerase 2
chr12_+_4310334 0.01 ENSRNOT00000041244
vomeronasal 2 receptor, 60
chr15_+_56666012 0.01 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr11_-_61287914 0.01 ENSRNOT00000086286
spindle and centriole associated protein 1
chr19_-_44101365 0.01 ENSRNOT00000082182
transmembrane protein 170A
chr2_+_248178389 0.01 ENSRNOT00000037339
guanylate binding protein 5
chr9_-_14599594 0.01 ENSRNOT00000018138
triggering receptor expressed on myeloid cells-like 1
chr20_+_11114164 0.01 ENSRNOT00000001602
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_+_34489940 0.01 ENSRNOT00000085975
zinc finger protein 62
chr6_-_27487284 0.01 ENSRNOT00000084344
selenoprotein I
chr10_-_13446135 0.01 ENSRNOT00000084991
potassium channel tetramerization domain containing 5
chr7_+_44009069 0.01 ENSRNOT00000005523
MGAT4 family, member C
chrX_-_63807810 0.01 ENSRNOT00000084632
MAGE family member D1
chr8_+_61671513 0.01 ENSRNOT00000091128
protein tyrosine phosphatase, non-receptor type 9
chr17_-_90071408 0.01 ENSRNOT00000071978
decaprenyl diphosphate synthase subunit 1
chr1_-_22269831 0.01 ENSRNOT00000081804
syntaxin 7
chr2_+_266317745 0.01 ENSRNOT00000080305
wntless Wnt ligand secretion mediator
chr7_+_72599479 0.01 ENSRNOT00000018963

chr2_+_251002213 0.01 ENSRNOT00000080600
outer dense fiber of sperm tails 2-like
chr7_-_138483612 0.01 ENSRNOT00000085620
solute carrier family 38, member 4
chr5_+_47546014 0.01 ENSRNOT00000065882
BTB domain and CNC homolog 2
chr4_+_88328061 0.01 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr18_+_65388685 0.01 ENSRNOT00000080844
transcription factor 4
chr3_-_66279155 0.01 ENSRNOT00000079887
ceramide kinase-like
chr8_-_71533069 0.01 ENSRNOT00000021863
thyroid hormone receptor interactor 4
chr2_-_118882562 0.01 ENSRNOT00000058860
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr5_+_128083118 0.01 ENSRNOT00000079161
zinc finger CCHC-type containing 11
chr14_-_20816588 0.01 ENSRNOT00000033806
solute carrier family 4 member 4
chr5_-_39215102 0.01 ENSRNOT00000050653
kelch-like family member 32
chr2_-_120570355 0.01 ENSRNOT00000088442
FMR1 autosomal homolog 1
chr8_+_115193146 0.01 ENSRNOT00000056391
IQ motif containing F1
chr10_+_97771264 0.01 ENSRNOT00000005257
arylsulfatase G
chr5_-_70463546 0.01 ENSRNOT00000043184

chr1_+_259739955 0.01 ENSRNOT00000054719
ectonucleoside triphosphate diphosphohydrolase 1
chr2_+_188748359 0.01 ENSRNOT00000028038
SHC adaptor protein 1
chr4_+_88423412 0.01 ENSRNOT00000040163
vomeronasal 1 receptor 88
chr11_+_31539016 0.01 ENSRNOT00000072856
interferon alpha and beta receptor subunit 2
chr1_+_61733805 0.01 ENSRNOT00000086029
similar to Zinc finger protein 208
chr1_+_17602281 0.01 ENSRNOT00000075461
jouberin-like
chr20_-_6195463 0.01 ENSRNOT00000092474
peroxisomal, testis specific 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:1905218 cellular response to astaxanthin(GO:1905218)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.0 0.0 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.0 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.0 GO:0010070 zygote asymmetric cell division(GO:0010070) targeting of mRNA for destruction involved in RNA interference(GO:0030423) regulation of enamel mineralization(GO:0070173)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 0.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.0 GO:0015563 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins