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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Pou2f1
Z-value: 0.81
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Transcription factors associated with Pou2f1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou2f1 | rn6_v1_chr13_-_84217332_84217366 | 0.33 | 5.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_-_126710854 Show fit | 0.37 |
ENSRNOT00000081127
ENSRNOT00000064914 |
BTB domain containing 7 |
|
| chr6_-_76535517 Show fit | 0.28 |
ENSRNOT00000083857
|
Ral GTPase activating protein catalytic alpha subunit 1 |
|
| chr18_+_30890869 Show fit | 0.27 |
ENSRNOT00000060466
|
protocadherin gamma subfamily B, 6 |
|
| chr10_+_56381813 Show fit | 0.27 |
ENSRNOT00000019687
|
zinc finger and BTB domain containing 4 |
|
| chr12_-_38782010 Show fit | 0.26 |
ENSRNOT00000001813
|
WD repeat domain 66 |
|
| chr1_-_67134827 Show fit | 0.25 |
ENSRNOT00000045214
|
vomeronasal 1 receptor 45 |
|
| chr5_-_164648328 Show fit | 0.25 |
ENSRNOT00000090811
|
zinc finger protein 933 |
|
| chr4_+_94696965 Show fit | 0.25 |
ENSRNOT00000064696
|
glutamate ionotropic receptor delta type subunit 2 |
|
| chr7_-_9976367 Show fit | 0.24 |
ENSRNOT00000044241
|
zinc finger protein 347 |
|
| chr6_+_64224861 Show fit | 0.24 |
ENSRNOT00000093159
ENSRNOT00000093664 |
patatin-like phospholipase domain containing 8 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Pou2f1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.0 | 0.3 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.1 | 0.2 | GO:0031959 | mineralocorticoid receptor signaling pathway(GO:0031959) |
| 0.1 | 0.2 | GO:0002835 | negative regulation of T cell mediated cytotoxicity(GO:0001915) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) cytotoxic T cell degranulation(GO:0043316) positive regulation of activation-induced cell death of T cells(GO:0070237) insulin catabolic process(GO:1901143) |
| 0.1 | 0.2 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 0.2 | GO:1990962 | carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963) |
| 0.0 | 0.2 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 0.0 | 0.2 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
| 0.0 | 0.2 | GO:0051764 | actin filament network formation(GO:0051639) actin crosslink formation(GO:0051764) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.2 | GO:0014731 | spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.1 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.0 | 0.1 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.0 | 0.1 | GO:0044308 | axonal spine(GO:0044308) |
| 0.0 | 0.0 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.3 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 0.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 0.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.0 | 0.2 | GO:0001729 | ceramide kinase activity(GO:0001729) |
| 0.0 | 0.2 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
| 0.0 | 0.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.2 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 0.2 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.2 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |