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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Pou1f1
Z-value: 1.76
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Transcription factors associated with Pou1f1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou1f1 | rn6_v1_chr11_+_2645865_2645865 | -0.01 | 9.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_+_14136883 Show fit | 2.51 |
ENSRNOT00000082295
|
|
|
| chr2_+_149899836 Show fit | 1.41 |
ENSRNOT00000086481
|
similar to hypothetical protein C130079G13 |
|
| chr9_-_20528879 Show fit | 1.02 |
ENSRNOT00000085293
|
|
|
| chr5_+_6373583 Show fit | 0.96 |
ENSRNOT00000084749
|
|
|
| chr15_+_36865548 Show fit | 0.95 |
ENSRNOT00000076460
|
poly (ADP-ribose) polymerase family, member 4 |
|
| chr7_-_116106368 Show fit | 0.87 |
ENSRNOT00000035678
|
lymphocyte antigen 6 complex, locus K |
|
| chr4_+_22859622 Show fit | 0.82 |
ENSRNOT00000073501
ENSRNOT00000068410 |
ADAM metallopeptidase domain 22 |
|
| chrM_+_11736 Show fit | 0.73 |
ENSRNOT00000048767
|
mitochondrially encoded NADH dehydrogenase 5 |
|
| chr7_+_2300434 Show fit | 0.69 |
ENSRNOT00000071785
|
|
|
| chr8_+_29714285 Show fit | 0.66 |
ENSRNOT00000042890
|
opioid binding protein/cell adhesion molecule-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of Pou1f1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 1.2 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.0 | 1.0 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.2 | 0.9 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.8 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.2 | 0.7 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.1 | 0.7 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 0.7 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
| 0.1 | 0.7 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.0 | 0.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0044450 | microtubule organizing center part(GO:0044450) |
| 0.0 | 1.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 0.8 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.2 | 0.7 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.0 | 0.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.7 | GO:0043034 | costamere(GO:0043034) |
| 0.2 | 0.6 | GO:0044317 | rod spherule(GO:0044317) |
| 0.1 | 0.6 | GO:0030314 | junctional membrane complex(GO:0030314) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 0.9 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.0 | 0.9 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.2 | 0.8 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.1 | 0.8 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.7 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.0 | 0.7 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.7 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.7 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.7 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.6 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 0.5 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.4 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.7 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.7 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 0.6 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.5 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.5 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.5 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.5 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |