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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pitx2_Otx2

Z-value: 0.70

Motif logo

Transcription factors associated with Pitx2_Otx2

Gene Symbol Gene ID Gene Info
ENSRNOG00000010681 paired-like homeodomain 2
ENSRNOG00000056186 orthodenticle homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx2rn6_v1_chr2_+_233602732_2336027320.932.1e-02Click!
Otx2rn6_v1_chr15_-_25521393_255213930.652.4e-01Click!

Activity profile of Pitx2_Otx2 motif

Sorted Z-values of Pitx2_Otx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_123119460 0.72 ENSRNOT00000028833
arginine vasopressin
chr4_+_86275717 0.71 ENSRNOT00000016414
protein phosphatase 1, regulatory subunit 17
chr16_+_20020444 0.50 ENSRNOT00000024827
6-phosphogluconolactonase
chr10_-_59883839 0.46 ENSRNOT00000093579
aspartoacylase
chr12_-_48365784 0.40 ENSRNOT00000077317
D-amino-acid oxidase
chr2_-_210116038 0.36 ENSRNOT00000074950
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr1_-_166939541 0.34 ENSRNOT00000079675
folate receptor 1
chr9_+_20004280 0.34 ENSRNOT00000075670
ankyrin repeat domain 66
chr8_-_132345708 0.33 ENSRNOT00000006300
transmembrane protein 158
chr2_-_113616766 0.32 ENSRNOT00000016858
ENSRNOT00000074723
transmembrane protein 212
chr15_+_38095803 0.31 ENSRNOT00000086854
mitochondrial ribosomal protein L57
chr7_-_145174771 0.31 ENSRNOT00000055270
glycosylation dependent cell adhesion molecule 1
chr10_+_55626741 0.31 ENSRNOT00000008492
aurora kinase B
chr6_+_8886591 0.30 ENSRNOT00000091510
ENSRNOT00000089174
SIX homeobox 3
chr10_-_59888198 0.29 ENSRNOT00000093482
ENSRNOT00000049311
ENSRNOT00000093230
aspartoacylase
chr19_-_57333433 0.28 ENSRNOT00000024917
angiotensinogen
chr19_+_14835822 0.27 ENSRNOT00000072804
RIKEN cDNA 1700007B14 gene
chr1_+_87224677 0.25 ENSRNOT00000028070
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr6_+_22296128 0.25 ENSRNOT00000087805
dpy-30 histone methyltransferase complex regulatory subunit
chrM_+_7758 0.25 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr20_+_14095914 0.25 ENSRNOT00000093404
guanylyl cyclase domain containing 1
chr6_+_123361864 0.25 ENSRNOT00000057577

chr10_+_40247436 0.25 ENSRNOT00000079830
glutathione peroxidase 3
chr18_+_63098144 0.24 ENSRNOT00000024968
cell death-inducing DFFA-like effector a
chr3_-_147819571 0.24 ENSRNOT00000009840
tribbles pseudokinase 3
chr5_-_169467153 0.24 ENSRNOT00000014536
hes family bHLH transcription factor 3
chr19_-_37528011 0.24 ENSRNOT00000059628
agouti related neuropeptide
chr1_-_88881460 0.23 ENSRNOT00000028287
hematopoietic cell signal transducer
chr9_+_88964525 0.23 ENSRNOT00000068236
dynein assembly factor with WD repeats 1
chr10_-_66229311 0.22 ENSRNOT00000016897
lectin, galactose binding, soluble 5
chr20_+_6356423 0.22 ENSRNOT00000000628
cyclin-dependent kinase inhibitor 1A
chr7_+_11769400 0.22 ENSRNOT00000044417
junctional sarcoplasmic reticulum protein 1
chr11_+_67465236 0.22 ENSRNOT00000042374
stefin A2
chr9_-_121972055 0.21 ENSRNOT00000089735
clusterin-like protein 1
chr5_-_156734541 0.21 ENSRNOT00000021036
cytidine deaminase-like
chr5_+_151413382 0.21 ENSRNOT00000012626
CD164 molecule like 2
chr1_+_214016897 0.21 ENSRNOT00000075588
tetraspanin-4-like
chr1_-_216663720 0.21 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr1_-_85510114 0.20 ENSRNOT00000074665
EP300 interacting inhibitor of differentiation 2B
chr2_+_140708397 0.20 ENSRNOT00000088846
microsomal glutathione S-transferase 2
chr16_-_75648538 0.19 ENSRNOT00000048414
defensin beta 14
chr3_+_148234193 0.19 ENSRNOT00000010418
cytochrome c oxidase subunit 4i2
chr20_-_13657943 0.19 ENSRNOT00000032290
pre-B lymphocyte 3
chr10_+_39066716 0.18 ENSRNOT00000010729
interleukin 5
chr1_-_167005839 0.18 ENSRNOT00000027261
leucine rich repeat containing 51
chr5_-_154438361 0.18 ENSRNOT00000085003

chr5_-_144345531 0.17 ENSRNOT00000014721
tektin 2
chr9_+_14951047 0.17 ENSRNOT00000074267
uncharacterized LOC100911489
chr4_+_145580799 0.17 ENSRNOT00000013727
von Hippel-Lindau tumor suppressor
chr7_-_136997050 0.17 ENSRNOT00000009143
developing brain homeobox 2
chr16_-_47535358 0.17 ENSRNOT00000040731
claudin 22
chr10_-_45534570 0.17 ENSRNOT00000058362
gap junction protein, gamma 2
chr8_+_128829680 0.16 ENSRNOT00000025279
myelin-associated oligodendrocyte basic protein
chr7_-_29152442 0.16 ENSRNOT00000079774
myosin binding protein C, slow type
chr4_+_170766900 0.16 ENSRNOT00000044446
H2A histone family, member J
chr10_-_90307658 0.16 ENSRNOT00000092102
solute carrier family 4 member 1
chr7_+_120320547 0.16 ENSRNOT00000014817
eukaryotic translation initiation factor 3, subunit L
chr12_-_38782010 0.16 ENSRNOT00000001813
WD repeat domain 66
chr13_-_52136127 0.16 ENSRNOT00000009398
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr16_+_36116258 0.15 ENSRNOT00000017652
Sin3A associated protein 30
chr15_+_61879184 0.15 ENSRNOT00000042606
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr16_-_20890949 0.15 ENSRNOT00000081977
homer scaffolding protein 3
chr19_+_37229120 0.15 ENSRNOT00000076335
heat shock transcription factor 4
chr19_-_25166528 0.15 ENSRNOT00000007775
relaxin 3
chr5_-_77945016 0.15 ENSRNOT00000076223
zinc finger protein 37
chr20_-_13667333 0.15 ENSRNOT00000031472
coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
chr12_-_13924531 0.14 ENSRNOT00000001477
solute carrier family 29 member 4
chr16_+_83358116 0.14 ENSRNOT00000031109
RAB20, member RAS oncogene family
chr8_-_87879888 0.14 ENSRNOT00000017048
interphotoreceptor matrix proteoglycan 1
chr4_+_84423653 0.14 ENSRNOT00000012655
chimerin 2
chr16_+_20109200 0.14 ENSRNOT00000079784
Janus kinase 3
chr12_-_47919400 0.14 ENSRNOT00000073774
mevalonate kinase
chr13_-_111474411 0.14 ENSRNOT00000072729
hedgehog acyltransferase
chr10_-_109979712 0.14 ENSRNOT00000086042
dihydrouridine synthase 1-like
chr16_-_21017163 0.14 ENSRNOT00000027661
myocyte enhancer factor 2B
chr9_+_16139101 0.14 ENSRNOT00000070803
uncharacterized LOC100910668
chr12_+_25264400 0.14 ENSRNOT00000087656
GTF2I repeat domain containing 1
chr20_+_5080070 0.14 ENSRNOT00000086950
ENSRNOT00000077082
abhydrolase domain containing 16A
chr1_+_81643816 0.14 ENSRNOT00000027214
carcinoembryonic antigen-related cell adhesion molecule 1-like
chr5_-_135859643 0.14 ENSRNOT00000024719
uroporphyrinogen decarboxylase
chr10_+_48240127 0.13 ENSRNOT00000080682
sperm antigen with calponin homology and coiled-coil domains 1
chr12_-_38805121 0.13 ENSRNOT00000057716
proteasome 26S subunit, non-ATPase 9
chr5_+_159606647 0.13 ENSRNOT00000051693
ribosomal protein S21, pseudogene 1
chr12_-_2007516 0.13 ENSRNOT00000037564
peroxisomal biogenesis factor 11 gamma
chr11_+_64882288 0.13 ENSRNOT00000077727
phospholipase A1 member A
chr2_+_235311719 0.13 ENSRNOT00000080183
ENSRNOT00000087287
phospholipase A2, group XIIA
chr4_-_120414118 0.12 ENSRNOT00000072795
40S ribosomal protein S25-like
chr5_-_17061361 0.12 ENSRNOT00000089318
proenkephalin
chr3_-_8315910 0.12 ENSRNOT00000074482
proline-rich protein HaeIII subfamily 1-like
chr10_-_97750679 0.12 ENSRNOT00000078059
solute carrier family 16, member 6
chr10_-_88677055 0.12 ENSRNOT00000025590
GH3 domain containing
chr10_-_10767389 0.12 ENSRNOT00000066754
small integral membrane protein 22
chr15_+_24141651 0.12 ENSRNOT00000082304
galectin 3
chr9_+_23420654 0.12 ENSRNOT00000073595
hypothetical protein LOC688459
chr1_-_80609836 0.12 ENSRNOT00000091647
ENSRNOT00000046169
apolipoprotein C1
chr3_+_163552166 0.12 ENSRNOT00000049082
TP53 regulating kinase
chr8_-_55491152 0.12 ENSRNOT00000014965
rCG58364-like
chr1_-_102255459 0.12 ENSRNOT00000067392
USH1 protein network component harmonin
chr8_+_71914867 0.11 ENSRNOT00000023372
death-associated protein kinase 2
chr16_+_71242470 0.11 ENSRNOT00000030489
leucine zipper and EF-hand containing transmembrane protein 2
chr14_-_80680738 0.11 ENSRNOT00000077706
smoothelin-like
chr14_+_10692764 0.11 ENSRNOT00000003012
uncharacterized LOC100910270
chrX_-_124516705 0.11 ENSRNOT00000061493
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
chr5_+_157282669 0.11 ENSRNOT00000022827
phospholipase A2 group IIA
chr1_-_80835701 0.11 ENSRNOT00000064305
poliovirus receptor
chr1_-_266862842 0.11 ENSRNOT00000027496
up-regulated during skeletal muscle growth protein 5
chr1_+_78659435 0.11 ENSRNOT00000071271
carcinoembryonic antigen-related cell adhesion molecule 9
chr16_-_74330911 0.11 ENSRNOT00000084330
solute carrier family 20 member 2
chr3_+_2438089 0.11 ENSRNOT00000013335
family with sequence similarity 166, member A
chr1_+_199449973 0.11 ENSRNOT00000029994
tripartite motif containing 72
chr16_+_7758996 0.11 ENSRNOT00000061063
biotinidase
chr12_+_25264192 0.11 ENSRNOT00000079392
GTF2I repeat domain containing 1
chr2_-_187706300 0.11 ENSRNOT00000092349
ENSRNOT00000026414
transmembrane protein 79
chr15_+_50891127 0.11 ENSRNOT00000020728
stanniocalcin 1
chr7_-_12640232 0.10 ENSRNOT00000014981
elastase, neutrophil expressed
chr2_-_196415530 0.10 ENSRNOT00000064238
similar to hypothetical protein FLJ20519
chr4_-_50860756 0.10 ENSRNOT00000068404
calcium dependent secretion activator 2
chr1_+_90919076 0.10 ENSRNOT00000081362
calpain small subunit 1-like
chr1_+_100393303 0.10 ENSRNOT00000026251
synaptotagmin 3
chr10_+_12929471 0.10 ENSRNOT00000036563
zinc finger and SCAN domain containing 10
chr2_-_187854363 0.10 ENSRNOT00000092993
lamin A/C
chr20_-_4935887 0.10 ENSRNOT00000064734
RT1 class I, locus CE4
chr5_-_136023511 0.10 ENSRNOT00000081747
ribosomal protein S8
chr3_-_10153554 0.10 ENSRNOT00000093246
exosome component 2
chr12_+_23752844 0.10 ENSRNOT00000001953
scavenger receptor cysteine rich family member with 4 domains
chr3_+_15379109 0.10 ENSRNOT00000036495
MORN repeat containing 5
chr19_+_10731855 0.10 ENSRNOT00000022277
plasmolipin
chr1_-_214163808 0.10 ENSRNOT00000082284
ribonuclease/angiogenin inhibitor 1
chr19_+_26142720 0.10 ENSRNOT00000005270
similar to RIKEN cDNA 2310036O22
chr1_-_89473904 0.10 ENSRNOT00000089474
FXYD domain-containing ion transport regulator 5
chr11_+_33909439 0.10 ENSRNOT00000002310
carbonyl reductase 3
chr5_+_138300107 0.10 ENSRNOT00000047151
claudin 19
chr8_+_118926478 0.10 ENSRNOT00000028426
coiled-coil domain containing 12
chr2_+_150211898 0.10 ENSRNOT00000018767
succinate receptor 1
chr1_-_188190778 0.10 ENSRNOT00000092657
ENSRNOT00000022988
coenzyme Q7, hydroxylase
chr2_-_198339130 0.10 ENSRNOT00000028767
bolA family member 1
chr11_-_27971359 0.10 ENSRNOT00000085629
ENSRNOT00000051060
ENSRNOT00000042581
ENSRNOT00000050073
ENSRNOT00000081066
glutamate ionotropic receptor kainate type subunit 1
chr4_+_172119331 0.10 ENSRNOT00000010579
microsomal glutathione S-transferase 1
chr1_+_101152734 0.10 ENSRNOT00000028022
PIH1 domain containing 1
chr8_-_117932518 0.10 ENSRNOT00000028130
cathelicidin antimicrobial peptide
chr3_+_79876938 0.09 ENSRNOT00000015757
proteasome 26S subunit, ATPase 3
chr5_-_72287669 0.09 ENSRNOT00000022255
Kruppel like factor 4
chr2_+_197682000 0.09 ENSRNOT00000066821
HORMA domain containing 1
chr10_+_108395860 0.09 ENSRNOT00000075796
glucosidase, alpha, acid
chr10_-_109909646 0.09 ENSRNOT00000074362
ENSRNOT00000088907
dicarbonyl and L-xylulose reductase
chr3_+_66673246 0.09 ENSRNOT00000081338
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr10_-_13780283 0.09 ENSRNOT00000084200

chr2_-_148807813 0.09 ENSRNOT00000047649

chr13_+_48689962 0.09 ENSRNOT00000079707
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_7801438 0.09 ENSRNOT00000022273

chr4_-_100783750 0.09 ENSRNOT00000078956
potassium channel modulatory factor 1
chr9_+_95274707 0.09 ENSRNOT00000045163
UDP glucuronosyltransferase family 1 member A5
chr19_-_26243223 0.09 ENSRNOT00000037766
zinc finger protein 791
chr7_+_11321057 0.09 ENSRNOT00000027737
mitochondrial ribosomal protein L54
chr10_-_94576512 0.09 ENSRNOT00000035474
intercellular adhesion molecule 2
chr2_-_56151531 0.09 ENSRNOT00000040847
ENSRNOT00000080677
oncostatin M receptor
chr4_-_120408232 0.09 ENSRNOT00000073269
40S ribosomal protein S25-like
chr3_+_170996193 0.09 ENSRNOT00000008959
SPO11, initiator of meiotic double stranded breaks
chr5_+_135997052 0.09 ENSRNOT00000024921
Tctex1 domain containing 4
chrX_-_63803915 0.09 ENSRNOT00000076938
MAGE family member D1
chr8_+_14060394 0.09 ENSRNOT00000014827
single-pass membrane protein with coiled-coil domains 4
chr10_+_83104622 0.09 ENSRNOT00000072972

chr17_-_32015071 0.09 ENSRNOT00000070876
leukocyte elastase inhibitor A-like
chr10_+_56662561 0.08 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr7_-_14217778 0.08 ENSRNOT00000038961
epoxide hydrolase 3
chr10_+_40208223 0.08 ENSRNOT00000000772
histidine triad nucleotide binding protein 1
chr8_+_118525682 0.08 ENSRNOT00000028288
elongator acetyltransferase complex subunit 6
chr3_+_161343883 0.08 ENSRNOT00000023202
PDX1 C-terminal inhibiting factor 1
chr19_+_26016382 0.08 ENSRNOT00000004601
Kruppel like factor 1
chr2_-_88553086 0.08 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr8_-_122841477 0.08 ENSRNOT00000014861
CKLF-like MARVEL transmembrane domain containing 7
chr7_+_116671948 0.08 ENSRNOT00000077773
ENSRNOT00000029711
GLI family zinc finger 4
chr4_+_118814284 0.08 ENSRNOT00000024884
NFU1 iron-sulfur cluster scaffold
chr11_+_72044096 0.08 ENSRNOT00000034757
SUMO1/sentrin specific peptidase 5
chr14_-_44375804 0.08 ENSRNOT00000042825
ribosomal protein P2-like
chr10_-_59112788 0.08 ENSRNOT00000041886
SPNS sphingolipid transporter 3
chr16_-_61753476 0.08 ENSRNOT00000016792
store-operated calcium entry-associated regulatory factor
chr5_-_17061837 0.08 ENSRNOT00000011892
proenkephalin
chr11_+_72892448 0.08 ENSRNOT00000075655
sentrin-specific protease 5
chr5_+_29538380 0.08 ENSRNOT00000010845
calbindin 1
chr10_+_37215937 0.08 ENSRNOT00000006567
secretion associated, Ras related GTPase 1B
chr19_-_37912027 0.08 ENSRNOT00000026462
proteasome subunit beta 10
chr1_-_90685257 0.08 ENSRNOT00000037700
carbohydrate sulfotransferase 8
chr10_-_82374171 0.08 ENSRNOT00000032693
essential meiotic structure-specific endonuclease 1
chr17_+_57040023 0.08 ENSRNOT00000020204
cAMP responsive element modulator
chr15_-_37826211 0.08 ENSRNOT00000064702
eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1
chr13_+_52553775 0.08 ENSRNOT00000011991
cysteine and glycine-rich protein 1
chr2_+_248723255 0.08 ENSRNOT00000015032
general transcription factor IIB
chr1_+_222311253 0.08 ENSRNOT00000028749
MACRO domain containing 1
chr7_-_117364322 0.08 ENSRNOT00000080724
5-oxoprolinase (ATP-hydrolysing)
chr10_+_89352835 0.08 ENSRNOT00000028060
ribosomal protein L27
chr7_-_123088279 0.08 ENSRNOT00000071998
transducer of ERBB2, 2
chr8_-_61919874 0.08 ENSRNOT00000064830
similar to human chromosome 15 open reading frame 39
chr3_-_10371240 0.08 ENSRNOT00000012075
argininosuccinate synthase 1
chr1_+_15093599 0.08 ENSRNOT00000016354
interleukin 22 receptor subunit alpha 2
chr19_+_24701049 0.08 ENSRNOT00000035890
NADH:ubiquinone oxidoreductase subunit B7
chr1_+_219390523 0.07 ENSRNOT00000054852
G protein-coupled receptor 152
chr8_-_14292698 0.07 ENSRNOT00000073672

chr14_-_79462080 0.07 ENSRNOT00000082180
GrpE-like 1, mitochondrial
chr14_+_44524753 0.07 ENSRNOT00000076245
ribosomal protein L9

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.4 GO:0006524 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.1 0.3 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0001998 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of renal output by angiotensin(GO:0002019) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.3 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.2 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.1 0.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0000053 argininosuccinate metabolic process(GO:0000053)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.1 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.0 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.1 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.1 GO:0070268 cuticle development(GO:0042335) cornification(GO:0070268)
0.0 0.2 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.0 0.1 GO:0071049 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.0 0.1 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0010037 response to carbon dioxide(GO:0010037)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.6 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0051005 regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632) cadmium ion homeostasis(GO:0055073)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0072702 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) response to environmental enrichment(GO:0090648) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0019046 viral latency(GO:0019042) release from viral latency(GO:0019046)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.0 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0019370 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.0 0.0 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.0 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.0 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.0 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.0 0.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.0 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0002339 B cell selection(GO:0002339)
0.0 0.1 GO:0060631 regulation of meiosis I(GO:0060631)
0.0 0.0 GO:0006311 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.0 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.0 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.0 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.0 GO:0043366 beta selection(GO:0043366)
0.0 0.0 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.0 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.0 0.0 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.0 GO:0046038 guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.0 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0051790 threonine metabolic process(GO:0006566) short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:1990005 granular vesicle(GO:1990005)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.0 GO:0061474 phagolysosome membrane(GO:0061474)
0.0 0.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0019807 aspartoacylase activity(GO:0019807)
0.2 0.7 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0001565 phorbol ester receptor activity(GO:0001565)
0.0 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) advanced glycation end-product receptor activity(GO:0050785)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0099510 calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0046911 metal chelating activity(GO:0046911)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.0 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.0 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.0 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell