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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Phox2a

Z-value: 0.41

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Transcription factors associated with Phox2a

Gene Symbol Gene ID Gene Info
ENSRNOG00000019706 paired-like homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Phox2arn6_v1_chr1_+_166893734_1668937340.642.4e-01Click!

Activity profile of Phox2a motif

Sorted Z-values of Phox2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 1.08 ENSRNOT00000001313
Purkinje cell protein 2
chr10_-_88670430 0.50 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr2_+_145174876 0.36 ENSRNOT00000040631
mab-21 like 1
chr2_-_185852759 0.24 ENSRNOT00000049461
mab-21 like 2
chr1_-_190370499 0.14 ENSRNOT00000084389

chr9_+_15166118 0.08 ENSRNOT00000020432
MyoD family inhibitor
chrX_+_74200972 0.08 ENSRNOT00000076956
cysteine-rich hydrophobic domain 1
chr3_+_14889510 0.07 ENSRNOT00000080760
DAB2 interacting protein
chr10_+_61685645 0.06 ENSRNOT00000003933
MAX network transcriptional repressor
chrX_-_104932508 0.06 ENSRNOT00000075325
NADPH oxidase 1
chr12_+_49665282 0.05 ENSRNOT00000086397
G protein-coupled receptor kinase 3
chr2_+_158097843 0.05 ENSRNOT00000016541
pentraxin 3
chrX_+_74205842 0.04 ENSRNOT00000077003
cysteine-rich hydrophobic domain 1
chr12_-_35979193 0.04 ENSRNOT00000071104
transmembrane protein 132B
chr2_+_80269661 0.03 ENSRNOT00000015975

chr3_+_3389612 0.02 ENSRNOT00000041984
ribosomal protein L8
chr2_+_239415046 0.02 ENSRNOT00000072196
CXXC finger protein 4
chr16_-_29936307 0.01 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr3_-_46942966 0.01 ENSRNOT00000087439
RNA binding motif, single stranded interacting protein 1
chr5_+_36566783 0.01 ENSRNOT00000077650
F-box and leucine-rich repeat protein 4
chr2_+_118910587 0.01 ENSRNOT00000065518
zinc finger protein 639
chr9_+_71915421 0.01 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr4_-_58250798 0.01 ENSRNOT00000048436
Kruppel-like factor 14
chr4_-_18396035 0.00 ENSRNOT00000034692
semaphorin 3A
chr13_+_90943255 0.00 ENSRNOT00000011539
V-set and immunoglobulin domain containing 8
chr1_-_101095594 0.00 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr14_-_84334066 0.00 ENSRNOT00000006160
mitochondrial fission process 1
chr1_-_101819478 0.00 ENSRNOT00000056181
glutamate-rich WD repeat containing 1
chr8_+_104106740 0.00 ENSRNOT00000015015
transcription factor Dp-2

Network of associatons between targets according to the STRING database.

First level regulatory network of Phox2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0043324 eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.0 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726) oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)