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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Pbx2
Z-value: 0.43
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Transcription factors associated with Pbx2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pbx2 | rn6_v1_chr20_+_4357733_4357733 | 0.15 | 8.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_147756294 Show fit | 0.18 |
ENSRNOT00000014537
|
methyl-CpG binding domain 4 DNA glycosylase |
|
| chrM_+_11736 Show fit | 0.16 |
ENSRNOT00000048767
|
mitochondrially encoded NADH dehydrogenase 5 |
|
| chr7_+_125288081 Show fit | 0.15 |
ENSRNOT00000085216
|
parvin, gamma |
|
| chr1_-_155955173 Show fit | 0.10 |
ENSRNOT00000079345
|
|
|
| chr9_+_67699379 Show fit | 0.08 |
ENSRNOT00000091237
ENSRNOT00000088183 |
cytotoxic T-lymphocyte-associated protein 4 |
|
| chr19_+_43338166 Show fit | 0.07 |
ENSRNOT00000091720
ENSRNOT00000084739 |
fucokinase |
|
| chr17_+_70262363 Show fit | 0.06 |
ENSRNOT00000048933
|
family with sequence similarity 208, member B |
|
| chr12_-_37682964 Show fit | 0.06 |
ENSRNOT00000001421
|
similar to hypothetical protein FLJ38663 |
|
| chr7_-_81592206 Show fit | 0.06 |
ENSRNOT00000007979
|
angiopoietin 1 |
|
| chr4_+_123801174 Show fit | 0.06 |
ENSRNOT00000029055
|
similar to chromosome 3 open reading frame 20 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Pbx2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0042350 | GDP-L-fucose biosynthetic process(GO:0042350) |
| 0.0 | 0.1 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.0 | 0.1 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) |
| 0.0 | 0.1 | GO:0030210 | negative regulation of cytokine secretion involved in immune response(GO:0002740) heparin biosynthetic process(GO:0030210) |
| 0.0 | 0.0 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.0 | 0.0 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.0 | 0.0 | GO:0009227 | nucleotide-sugar catabolic process(GO:0009227) |
| 0.0 | 0.0 | GO:2000422 | T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424) |
| 0.0 | 0.0 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.0 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.0 | 0.1 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.0 | 0.0 | GO:0008453 | alanine-glyoxylate transaminase activity(GO:0008453) |
| 0.0 | 0.0 | GO:0005534 | galactose binding(GO:0005534) |
| 0.0 | 0.0 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |