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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pax5

Z-value: 1.11

Motif logo

Transcription factors associated with Pax5

Gene Symbol Gene ID Gene Info
ENSRNOG00000024729 paired box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax5rn6_v1_chr5_-_60191941_601919410.237.1e-01Click!

Activity profile of Pax5 motif

Sorted Z-values of Pax5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_150167077 0.85 ENSRNOT00000088493
ENSRNOT00000013761
ENSRNOT00000067349
ENSRNOT00000051097
ENSRNOT00000067189
erythrocyte membrane protein band 4.1
chr8_-_98738446 0.80 ENSRNOT00000019860
Zic family member 1
chr7_-_3342491 0.78 ENSRNOT00000081756
retinol dehydrogenase 5
chr20_+_5008508 0.73 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr2_-_259150479 0.71 ENSRNOT00000085892

chr6_-_27190126 0.62 ENSRNOT00000068412
ENSRNOT00000013107
potassium two pore domain channel subfamily K member 3
chr6_-_11494459 0.54 ENSRNOT00000021570
potassium two pore domain channel subfamily K member 12
chr10_-_88551056 0.49 ENSRNOT00000032737
zinc finger protein 385C
chr10_-_55642681 0.48 ENSRNOT00000057157

chr8_+_118066988 0.48 ENSRNOT00000056161
microtubule-associated protein 4
chr8_-_115167486 0.45 ENSRNOT00000033018
G protein-coupled receptor 62
chr6_+_110624856 0.45 ENSRNOT00000014017
vasohibin 1
chr5_-_156811650 0.44 ENSRNOT00000068065
family with sequence similarity 43, member B
chr19_+_55669626 0.43 ENSRNOT00000033352
cadherin 15
chr17_-_23923792 0.42 ENSRNOT00000018739
glucose-fructose oxidoreductase domain containing 1
chr20_+_4823662 0.41 ENSRNOT00000090028
NFKB inhibitor like 1
chr18_+_27558089 0.40 ENSRNOT00000027499
family with sequence similarity 53, member C
chr13_-_49313940 0.39 ENSRNOT00000012190
contactin 2
chr4_+_148139528 0.39 ENSRNOT00000092594
ENSRNOT00000015620
ENSRNOT00000092613
WASH complex subunit 2C
chr11_+_57207656 0.36 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr20_-_4823475 0.36 ENSRNOT00000082536
ENSRNOT00000001114
ATPase H+ transporting V1 subunit G2
chr20_+_3558827 0.36 ENSRNOT00000088130
discoidin domain receptor tyrosine kinase 1
chr13_+_71107465 0.35 ENSRNOT00000003239
regulator of G-protein signaling 8
chr2_+_195617021 0.34 ENSRNOT00000067042
ENSRNOT00000036656
RAR-related orphan receptor C
leucine rich repeat and Ig domain containing 4
chr12_+_28212333 0.33 ENSRNOT00000001182
autism susceptibility candidate 2
chrX_+_105239840 0.33 ENSRNOT00000039864
dystrophin related protein 2
chr3_+_80676820 0.32 ENSRNOT00000084809
autophagy and beclin 1 regulator 1
chr11_+_71151132 0.31 ENSRNOT00000082594
ENSRNOT00000082435
RUN and cysteine rich domain containing beclin 1 interacting protein
chr1_+_264504591 0.31 ENSRNOT00000050076
paired box 2
chr17_-_10818835 0.31 ENSRNOT00000091046
complexin 2
chr1_+_82253005 0.30 ENSRNOT00000027854

chr20_-_3386048 0.30 ENSRNOT00000089550
ENSRNOT00000065025
DEAH-box helicase 16
chr14_+_83724933 0.30 ENSRNOT00000029848
phospholipase A2, group III
chr7_-_119441487 0.30 ENSRNOT00000067635
parvalbumin
chr5_+_169475270 0.29 ENSRNOT00000014625
isoprenylcysteine carboxyl methyltransferase
chr1_+_33910912 0.29 ENSRNOT00000044690
iroquois homeobox 1
chr6_-_111222858 0.29 ENSRNOT00000074707
transmembrane p24 trafficking protein 8
chr3_+_147609095 0.28 ENSRNOT00000041456
sulfiredoxin 1
chr10_-_62184874 0.28 ENSRNOT00000004229
replication protein A1
chr3_+_162692185 0.28 ENSRNOT00000007768
nuclear receptor coactivator 3
chr9_+_117795132 0.28 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chr10_+_78168715 0.28 ENSRNOT00000072294
COX11 cytochrome c oxidase copper chaperone
chr5_-_166133491 0.27 ENSRNOT00000087739
ENSRNOT00000089099
kinesin family member 1B
chr15_-_33775109 0.27 ENSRNOT00000033722
junctophilin 4
chr1_-_215846911 0.27 ENSRNOT00000089171
insulin-like growth factor 2
chr1_-_5165859 0.27 ENSRNOT00000044325
ENSRNOT00000019319
glutamate metabotropic receptor 1
chr3_-_160301552 0.26 ENSRNOT00000014498
regulating synaptic membrane exocytosis 4
chr10_+_109278712 0.26 ENSRNOT00000065565
hypothetical protein LOC690871
chr1_+_199449973 0.26 ENSRNOT00000029994
tripartite motif containing 72
chr3_+_11198401 0.26 ENSRNOT00000088576
ENSRNOT00000066368
proline-rich coiled-coil 2B
chr6_-_122897997 0.26 ENSRNOT00000057601
echinoderm microtubule associated protein like 5
chr4_+_168599331 0.26 ENSRNOT00000086719
cAMP responsive element binding protein-like 2
chr5_+_148661070 0.25 ENSRNOT00000056229
Sodium/potassium transporting ATPase interacting 1
chr6_+_24163026 0.25 ENSRNOT00000061284
limb bud and heart development
chr16_-_48437223 0.25 ENSRNOT00000013005
ENSRNOT00000059401
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr10_-_64657089 0.25 ENSRNOT00000080703
active BCR-related
chr15_-_44860604 0.25 ENSRNOT00000018637
neurofilament medium
chr20_+_4822935 0.24 ENSRNOT00000077200
NFKB inhibitor like 1
chr10_-_74679858 0.24 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr20_+_29655226 0.24 ENSRNOT00000089059
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2
chr12_-_11783232 0.24 ENSRNOT00000075888
zinc finger protein 498
chr7_-_117364697 0.24 ENSRNOT00000077314
5-oxoprolinase (ATP-hydrolysing)
chr10_-_62483342 0.24 ENSRNOT00000079956
hypermethylated in cancer 1 protein-like
chr1_-_57815038 0.23 ENSRNOT00000075401
repulsive guidance molecule family member B
chr17_-_27112820 0.23 ENSRNOT00000018359
bone morphogenetic protein 6
chr10_+_63829807 0.23 ENSRNOT00000006407
CRK proto-oncogene, adaptor protein
chr1_-_209641123 0.23 ENSRNOT00000021702
early B-cell factor 3
chr16_-_10726648 0.23 ENSRNOT00000080635
ENSRNOT00000087150
synuclein, gamma
chr1_+_165625350 0.23 ENSRNOT00000087534
RAB6A, member RAS oncogene family
chr7_-_117364322 0.22 ENSRNOT00000080724
5-oxoprolinase (ATP-hydrolysing)
chr10_+_56381813 0.22 ENSRNOT00000019687
zinc finger and BTB domain containing 4
chr16_-_81945127 0.22 ENSRNOT00000023352
MCF.2 cell line derived transforming sequence-like
chr2_-_32518643 0.22 ENSRNOT00000061032
microtubule associated serine/threonine kinase family member 4
chr7_-_11824742 0.22 ENSRNOT00000051467
DOT1 like histone lysine methyltransferase
chr14_+_83343330 0.21 ENSRNOT00000089198
phosphatidylserine decarboxylase
chr19_-_19832812 0.21 ENSRNOT00000084657
poly(A) RNA polymerase D5, non-canonical
chr1_-_100669684 0.21 ENSRNOT00000091760
myosin heavy chain 14
chr4_-_150471806 0.21 ENSRNOT00000008741
ENSRNOT00000076557
BMS1 ribosome biogenesis factor
chr13_-_51183269 0.21 ENSRNOT00000039540
PTPRF interacting protein alpha 4
chr3_+_93495106 0.21 ENSRNOT00000029922
ENSRNOT00000085760
ankyrin repeat and BTB domain containing 2
chr1_+_82174451 0.20 ENSRNOT00000027783
transmembrane protein 145
chr1_+_154606490 0.20 ENSRNOT00000024095
coiled-coil domain containing 89
chr3_-_110492398 0.20 ENSRNOT00000056450
ankyrin repeat domain 63
chrX_+_105500173 0.20 ENSRNOT00000040476
armadillo repeat containing, X-linked 4
chr15_-_108898703 0.20 ENSRNOT00000067577
Zic family member 5
chr5_+_76092287 0.20 ENSRNOT00000020207
zinc finger protein 483
chr20_+_5535432 0.20 ENSRNOT00000040859
synaptic Ras GTPase activating protein 1
chr1_-_198316882 0.20 ENSRNOT00000085304
ENSRNOT00000064985
TAO kinase 2
chr20_-_31597830 0.20 ENSRNOT00000085877
collagen type XIII alpha 1 chain
chr6_-_126582034 0.19 ENSRNOT00000010656
ENSRNOT00000080829
inositol-tetrakisphosphate 1-kinase
chr10_+_56662561 0.19 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr1_-_281874456 0.19 ENSRNOT00000084760
ENSRNOT00000050617
CDK2-associated, cullin domain 1
chr10_+_55707164 0.19 ENSRNOT00000009757
hes family bHLH transcription factor 7
chr18_+_55797198 0.19 ENSRNOT00000026334
ENSRNOT00000026394
dynactin subunit 4
chr1_+_221612584 0.18 ENSRNOT00000090100
autophagy related 2A
chr7_-_117978787 0.18 ENSRNOT00000074262
zinc finger protein 647
chr7_+_70364813 0.18 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_+_199196059 0.18 ENSRNOT00000090428
F-box and leucine-rich repeat protein 19
chr7_-_143793774 0.18 ENSRNOT00000079678
cysteine sulfinic acid decarboxylase
chr13_+_105684420 0.18 ENSRNOT00000040543
G patch domain containing 2
chr2_-_174413236 0.18 ENSRNOT00000064588
golgi integral membrane protein 4
chr2_+_207930796 0.18 ENSRNOT00000047827
potassium voltage-gated channel subfamily D member 3
chr7_-_24313885 0.18 ENSRNOT00000044331
BTB domain containing 11
chr20_+_7279820 0.18 ENSRNOT00000090820
protein kinase C and casein kinase substrate in neurons 1
chr1_-_43638161 0.17 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr11_-_83926524 0.17 ENSRNOT00000041777
ENSRNOT00000040029
eukaryotic translation initiation factor 4 gamma, 1
chr15_+_31243097 0.17 ENSRNOT00000042721
RGD1359684 protein-like
chr2_+_41157823 0.17 ENSRNOT00000066384
phosphodiesterase 4D
chr16_-_8685529 0.17 ENSRNOT00000092751
solute carrier family 18 member A3
chr5_+_142875773 0.17 ENSRNOT00000082120
ENSRNOT00000056496
EPH receptor A10
chr14_-_84170301 0.16 ENSRNOT00000080413
solute carrier family 35, member E4
chr4_-_115015965 0.16 ENSRNOT00000014603
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr1_+_226252226 0.16 ENSRNOT00000039369

chr7_-_3074359 0.16 ENSRNOT00000019738
IKAROS family zinc finger 4
chr14_+_84876781 0.16 ENSRNOT00000065188
activating signal cointegrator 1 complex subunit 2
chr8_+_109455786 0.16 ENSRNOT00000039593
male-specific lethal 2 homolog (Drosophila)
chr4_+_26470864 0.15 ENSRNOT00000021979
frizzled class receptor 1
chr9_+_119542328 0.15 ENSRNOT00000082005
lipin 2
chr19_-_1074333 0.15 ENSRNOT00000017983
ENSRNOT00000086995
cadherin 5
chr6_+_24160226 0.15 ENSRNOT00000091904
limb bud and heart development
chr5_+_58855773 0.15 ENSRNOT00000072869
RUN and SH3 domain containing 2
chr3_+_61658245 0.15 ENSRNOT00000033511
homeo box D3
chr1_-_192088520 0.15 ENSRNOT00000047420
partner and localizer of BRCA2
chr14_-_55081551 0.15 ENSRNOT00000049245
protocadherin 7
chr9_+_94425252 0.15 ENSRNOT00000064965
ENSRNOT00000076099
GRB10 interacting GYF protein 2
chr7_-_98709344 0.14 ENSRNOT00000064122
transmembrane protein 65
chr2_-_211831551 0.14 ENSRNOT00000039225
ENSRNOT00000090561
family with sequence similarity 102, member B
chr10_+_36098051 0.14 ENSRNOT00000083971
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr12_-_5773036 0.14 ENSRNOT00000041365
FRY microtubule binding protein
chr17_-_18421861 0.14 ENSRNOT00000060500
ENSRNOT00000036560
family with sequence similarity 8, member A1
chr7_-_67116980 0.14 ENSRNOT00000005798
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chrX_-_2657155 0.14 ENSRNOT00000005630
carbohydrate sulfotransferase 7
chr1_-_226791773 0.14 ENSRNOT00000082482
ENSRNOT00000065376
ENSRNOT00000054812
ENSRNOT00000086669
T-cell surface glycoprotein CD5-like
chr1_+_198932870 0.14 ENSRNOT00000055003
fibrosin
chr12_+_2589818 0.14 ENSRNOT00000087848

chr4_-_157274755 0.14 ENSRNOT00000088895
atrophin-1-like
chr10_-_56444847 0.14 ENSRNOT00000056872
ENSRNOT00000092662
neuroligin 2
chr2_+_187737770 0.14 ENSRNOT00000036143
ENSRNOT00000092611
ENSRNOT00000092620
progestin and adipoQ receptor family member 6
chr1_-_198460126 0.14 ENSRNOT00000082940
ENSRNOT00000086019
MYC associated zinc finger protein
chr2_-_174413038 0.14 ENSRNOT00000089229
ENSRNOT00000037115
golgi integral membrane protein 4
chr5_-_65073012 0.14 ENSRNOT00000007957
glutamate ionotropic receptor NMDA type subunit 3A
chr14_+_42714315 0.14 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr1_-_174119815 0.13 ENSRNOT00000019368
tripartite motif-containing 66
chr17_+_5225835 0.13 ENSRNOT00000022373
zinc finger CCHC-type containing 6
chr17_+_77185053 0.13 ENSRNOT00000091561
optineurin
chr19_+_11473541 0.13 ENSRNOT00000082066
autocrine motility factor receptor
chr16_+_7588217 0.13 ENSRNOT00000026525
ELL associated factor 1
chr5_-_168734296 0.13 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr1_-_93949187 0.13 ENSRNOT00000018956
zinc finger protein 536
chr5_+_144779681 0.13 ENSRNOT00000016493
dyslexia susceptibility 2-like
chr4_+_168752133 0.13 ENSRNOT00000010289
apolipoprotein L domain containing 1
chr6_+_99625306 0.13 ENSRNOT00000008573
pleckstrin homology and RhoGEF domain containing G3
chr17_-_10208360 0.13 ENSRNOT00000087397
unc-5 netrin receptor A
chr3_-_80003032 0.13 ENSRNOT00000017360
MAP-kinase activating death domain
chr10_-_55923964 0.13 ENSRNOT00000073296
centrobin, centriole duplication and spindle assembly protein
chr1_+_167374182 0.13 ENSRNOT00000092882
stromal interaction molecule 1
chr6_+_108285822 0.13 ENSRNOT00000015889
visual system homeobox 2
chr15_+_52241801 0.12 ENSRNOT00000082639
HR, lysine demethylase and nuclear receptor corepressor
chr19_-_38484611 0.12 ENSRNOT00000077960
nuclear factor of activated T-cells 5
chr13_-_51784639 0.12 ENSRNOT00000089068
protein phosphatase 1, regulatory subunit 12B
chr8_+_29453643 0.12 ENSRNOT00000090643
opioid binding protein/cell adhesion molecule-like
chr1_-_14412807 0.12 ENSRNOT00000074583
TNF alpha induced protein 3
chr2_-_62634785 0.12 ENSRNOT00000017937
PDZ domain containing 2
chr20_-_13706205 0.12 ENSRNOT00000038623
derlin 3
chr2_-_63166509 0.12 ENSRNOT00000018246
cadherin 6
chrX_+_71272042 0.12 ENSRNOT00000076034
ENSRNOT00000076816
gap junction protein, beta 1
chr13_-_89267402 0.12 ENSRNOT00000004179
dual specificity phosphatase 12
chr16_+_23668595 0.12 ENSRNOT00000067886
pleckstrin and Sec7 domain containing 3
chr8_-_61079526 0.12 ENSRNOT00000068658
pseudopodium-enriched atypical kinase 1
chr2_+_34186091 0.11 ENSRNOT00000016129
small glutamine rich tetratricopeptide repeat containing beta
chr3_-_148312420 0.11 ENSRNOT00000047416
ENSRNOT00000081272
Bcl2-like 1
chr2_-_206274079 0.11 ENSRNOT00000056079
homeodomain interacting protein kinase 1
chr10_+_70689863 0.11 ENSRNOT00000091122
ENSRNOT00000086987
ENSRNOT00000082030
TATA-box binding protein associated factor 15
chr11_-_73678984 0.11 ENSRNOT00000002355
family with sequence similarity 43, member A
chrX_-_1714061 0.11 ENSRNOT00000011592
cyclin-dependent kinase 16
chr4_+_64088900 0.11 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr14_+_115275894 0.11 ENSRNOT00000033437
G protein-coupled receptor 75
chr16_+_10727571 0.11 ENSRNOT00000084422
multimerin 2
chr1_-_219745654 0.11 ENSRNOT00000054848
hypothetical protein LOC689065
chr5_+_169181418 0.11 ENSRNOT00000004508
kelch-like family member 21
chr18_+_30574627 0.11 ENSRNOT00000060484
protocadherin beta 19
chr13_-_52266100 0.11 ENSRNOT00000087532

chrX_+_23081125 0.11 ENSRNOT00000071639

chr3_+_12262822 0.11 ENSRNOT00000022585
angiopoietin-like 2
chr1_-_264756546 0.11 ENSRNOT00000020020
mitochondrial ribosomal protein L43
chr15_+_30429974 0.11 ENSRNOT00000071797

chr3_+_55094637 0.11 ENSRNOT00000058763
ceramide synthase 6
chr20_+_11972381 0.10 ENSRNOT00000001642
adenosine deaminase, RNA-specific, B1
chr7_-_122403667 0.10 ENSRNOT00000088814
megakaryoblastic leukemia (translocation) 1
chr6_+_137997335 0.10 ENSRNOT00000006872
transmembrane protein 121
chr7_-_116255167 0.10 ENSRNOT00000038109
ENSRNOT00000041774
cytochrome P450, family 11, subfamily b, polypeptide 2
chr7_+_2752680 0.10 ENSRNOT00000033726
citrate synthase
chr9_+_16647922 0.10 ENSRNOT00000031625
kinesin light chain 4
chr14_-_84393421 0.10 ENSRNOT00000006911
coiled-coil domain containing 157
chr10_+_45258887 0.10 ENSRNOT00000048642
butyrophilin like 10
chr2_-_186515135 0.10 ENSRNOT00000077375
kin of IRRE like (Drosophila)
chrX_-_15707436 0.10 ENSRNOT00000085907
synaptophysin
chr1_-_127599257 0.10 ENSRNOT00000018436
ankyrin repeat and SOCS box-containing 7
chr10_+_108750620 0.10 ENSRNOT00000005337
regulatory associated protein of MTOR, complex 1
chr10_-_74769637 0.10 ENSRNOT00000008889
zinc finger protein OZF-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0035566 regulation of metanephros size(GO:0035566)
0.1 0.4 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 0.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.3 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.2 GO:1990859 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
0.1 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.3 GO:0042695 thelarche(GO:0042695) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.2 GO:0071464 cellular response to hydrostatic pressure(GO:0071464)
0.0 0.1 GO:0048880 medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
0.0 0.3 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0036395 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:1905218 cellular response to astaxanthin(GO:1905218)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0061744 motor behavior(GO:0061744)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.0 0.2 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.3 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0080033 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033)
0.0 0.1 GO:1903544 cellular response to interleukin-11(GO:0071348) response to butyrate(GO:1903544)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0033131 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.0 GO:0072004 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594)
0.0 0.2 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0061072 lens induction in camera-type eye(GO:0060235) iris morphogenesis(GO:0061072)
0.0 0.1 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.2 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0032342 aldosterone biosynthetic process(GO:0032342)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0060708 negative regulation of Schwann cell proliferation(GO:0010626) spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0070827 chromatin maintenance(GO:0070827)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.2 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0090534 longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0034481 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA