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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Pax4

Z-value: 0.37

Motif logo

Transcription factors associated with Pax4

Gene Symbol Gene ID Gene Info
ENSRNOG00000008020 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax4rn6_v1_chr4_-_55740627_55740627-0.355.6e-01Click!

Activity profile of Pax4 motif

Sorted Z-values of Pax4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_79823945 0.15 ENSRNOT00000014484
CUGBP, Elav-like family member 1
chr9_+_20765296 0.09 ENSRNOT00000016291
CD2-associated protein
chr13_-_45318822 0.09 ENSRNOT00000091514
ENSRNOT00000005143
C-X-C motif chemokine receptor 4
chr6_-_108796124 0.08 ENSRNOT00000086545
apoptosis resistant E3 ubiquitin protein ligase 1
chr16_-_9709347 0.07 ENSRNOT00000083933
mitogen-activated protein kinase 8
chr20_+_13940877 0.07 ENSRNOT00000093587
calcineurin binding protein 1
chr4_-_152883210 0.07 ENSRNOT00000056200
coiled-coil domain containing 77
chrX_+_128416722 0.07 ENSRNOT00000009336
ENSRNOT00000085110
X-linked inhibitor of apoptosis
chr3_-_148932878 0.07 ENSRNOT00000013881
nucleolar protein 4-like
chr18_-_74485139 0.06 ENSRNOT00000022598
solute carrier family 14 member 1
chr18_-_57245666 0.06 ENSRNOT00000080365
actin binding LIM protein family, member 3
chr3_-_71845232 0.06 ENSRNOT00000078645
calcitonin receptor like receptor
chr13_-_80775230 0.06 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr8_+_70317586 0.05 ENSRNOT00000016260
DENN domain containing 4A
chr2_-_22798214 0.05 ENSRNOT00000016135
poly(A) RNA polymerase D4, non-canonical
chr3_-_113438801 0.05 ENSRNOT00000091665
microfibrillar-associated protein 1A
chrX_-_152642531 0.05 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr14_-_112946204 0.05 ENSRNOT00000056813
coiled-coil domain-containing protein 85A-like
chrX_-_70428364 0.05 ENSRNOT00000045907
pyrimidinergic receptor P2Y4
chr14_+_8182383 0.05 ENSRNOT00000092719
mitogen activated protein kinase 10
chr10_+_90984227 0.05 ENSRNOT00000003890
ENSRNOT00000093707
coiled-coil domain containing 103
chr1_+_264309214 0.04 ENSRNOT00000019070
hypoxia-inducible factor 1, alpha subunit inhibitor
chr3_-_66417741 0.04 ENSRNOT00000007662
neuronal differentiation 1
chr3_-_162579201 0.04 ENSRNOT00000068328
zinc finger, MYND-type containing 8
chr1_+_105285419 0.04 ENSRNOT00000089693
solute carrier family 6 member 5
chrM_+_11736 0.04 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr1_+_252894663 0.04 ENSRNOT00000054757
interferon-induced protein with tetratricopeptide repeats 2
chr14_+_39663421 0.04 ENSRNOT00000003197
gamma-aminobutyric acid type A receptor alpha2 subunit
chr1_+_81779380 0.04 ENSRNOT00000065865
ENSRNOT00000080143
ENSRNOT00000089592
ENSRNOT00000080840
Rho guanine nucleotide exchange factor 1
chr6_-_50941248 0.04 ENSRNOT00000084533
dihydrouridine synthase 4-like
chr7_+_97559841 0.03 ENSRNOT00000007326
zinc fingers and homeoboxes 2
chr5_+_6373583 0.03 ENSRNOT00000084749

chr7_-_140437467 0.03 ENSRNOT00000087181
FK506 binding protein 11
chr8_+_12823155 0.03 ENSRNOT00000011008
sestrin 3
chr3_-_51297852 0.03 ENSRNOT00000001607
cordon-bleu WH2 repeat protein-like 1
chr7_+_117605050 0.03 ENSRNOT00000047380
solute carrier family 52 member 2
chr7_-_120295618 0.03 ENSRNOT00000014413
ankyrin repeat domain 54
chrM_+_9870 0.03 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr14_-_103321270 0.03 ENSRNOT00000006157
Meis homeobox 1
chr15_-_42947656 0.03 ENSRNOT00000030007
protein tyrosine kinase 2 beta
chr7_-_117605141 0.03 ENSRNOT00000035199
F-box and leucine-rich repeat protein 6
chr12_-_37411525 0.03 ENSRNOT00000087698
tectonic family member 2
chr14_+_99919485 0.02 ENSRNOT00000006087
epidermal growth factor receptor
chr8_-_53901358 0.02 ENSRNOT00000047666
ENSRNOT00000042281
neural cell adhesion molecule 1
chr1_+_116604550 0.02 ENSRNOT00000083587
ubiquitin protein ligase E3A
chr20_-_6257604 0.02 ENSRNOT00000092489
serine/threonine kinase 38
chr3_-_92749121 0.02 ENSRNOT00000008760
CD44 molecule (Indian blood group)
chr20_-_1878126 0.02 ENSRNOT00000000995
ubiquitin D
chr12_-_11176106 0.02 ENSRNOT00000090073
zinc finger with KRAB and SCAN domains 5
chr1_-_221370322 0.02 ENSRNOT00000028431
calpain 1
chr12_-_11175917 0.02 ENSRNOT00000079573
zinc finger with KRAB and SCAN domains 5
chr15_+_43298794 0.02 ENSRNOT00000012736
adrenoceptor alpha 1A
chr15_-_6587367 0.02 ENSRNOT00000038449
zinc finger protein 385D
chrX_-_116792707 0.02 ENSRNOT00000049482
angiomotin
chr20_-_4401610 0.02 ENSRNOT00000091468
palmitoyl-protein thioesterase 2
chr3_+_94530586 0.02 ENSRNOT00000067860
cleavage stimulation factor subunit 3
chr7_+_37018459 0.02 ENSRNOT00000087297
early endosome antigen 1
chr7_-_101140308 0.02 ENSRNOT00000006279
family with sequence similarity 84, member B
chr5_+_148781222 0.02 ENSRNOT00000015831
pumilio RNA-binding family member 1
chr9_-_10471009 0.02 ENSRNOT00000072868
scaffold attachment factor B
chr11_-_57993548 0.01 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr12_-_44999074 0.01 ENSRNOT00000079177
ENSRNOT00000038293
V-set and immunoglobulin domain containing 10
chr7_-_114573900 0.01 ENSRNOT00000011219
protein tyrosine kinase 2
chr1_-_248376750 0.01 ENSRNOT00000089073
glycine decarboxylase
chr7_-_119689938 0.01 ENSRNOT00000000200
transmembrane protease, serine 6
chr18_-_81682206 0.01 ENSRNOT00000058219
hypothetical protein LOC100359752
chr8_-_67040005 0.01 ENSRNOT00000038641
glucuronic acid epimerase
chr1_+_80092403 0.01 ENSRNOT00000078336
echinoderm microtubule associated protein like 2
chr20_-_44255064 0.01 ENSRNOT00000000735
WNT1 inducible signaling pathway protein 3
chr20_-_5076539 0.01 ENSRNOT00000076253
ENSRNOT00000037613
lymphocyte antigen 6 complex, locus G6F
chr6_+_28235695 0.01 ENSRNOT00000047210
DNA methyltransferase 3 alpha
chr13_+_49005405 0.01 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr8_+_107508351 0.01 ENSRNOT00000081594
centrosomal protein 70
chr4_+_110699557 0.01 ENSRNOT00000030588
ENSRNOT00000092261
leucine rich repeat transmembrane neuronal 4
chrX_+_105537602 0.01 ENSRNOT00000029833
armadillo repeat containing, X-linked 1
chr12_+_40244081 0.01 ENSRNOT00000030583
SH2B adaptor protein 3
chr4_-_158704170 0.01 ENSRNOT00000082009
neurotrophin 3
chrM_+_3904 0.01 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr6_-_103313074 0.01 ENSRNOT00000083677
zinc finger protein 36, C3H type-like 1
chr18_+_60392376 0.00 ENSRNOT00000023890
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr13_-_53108713 0.00 ENSRNOT00000035404
similar to hypothetical protein FLJ10901
chr13_+_90301006 0.00 ENSRNOT00000029315
SLAM family member 6
chr1_+_273854248 0.00 ENSRNOT00000044827
ENSRNOT00000017600
ENSRNOT00000086496
adducin 3
chr16_-_62164135 0.00 ENSRNOT00000058872
general transcription factor IIE subunit 2
chr18_+_30527705 0.00 ENSRNOT00000027168
protocadherin beta 14
chr10_-_25845634 0.00 ENSRNOT00000004269
methionine adenosyltransferase 2B
chr5_+_117583502 0.00 ENSRNOT00000010933
ubiquitin specific peptidase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:1990478 positive regulation of vascular wound healing(GO:0035470) response to ultrasound(GO:1990478)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.0 GO:0007172 signal complex assembly(GO:0007172)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.0 0.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion