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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Otx1

Z-value: 0.30

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Transcription factors associated with Otx1

Gene Symbol Gene ID Gene Info
ENSRNOG00000059469 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Otx1rn6_v1_chr14_-_106864892_1068648920.741.5e-01Click!

Activity profile of Otx1 motif

Sorted Z-values of Otx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_27047382 0.12 ENSRNOT00000027691
ENSRNOT00000090264
APC, WNT signaling pathway regulator
chr2_-_265300868 0.11 ENSRNOT00000066024
ENSRNOT00000016073
ENSRNOT00000033502
leucine rich repeat containing 7
chr19_+_26066127 0.11 ENSRNOT00000064289
retbindin
chr10_+_56381813 0.10 ENSRNOT00000019687
zinc finger and BTB domain containing 4
chr1_+_27476375 0.10 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr3_-_162059524 0.08 ENSRNOT00000033873
zinc finger protein 334
chr7_+_70946228 0.08 ENSRNOT00000039306
signal transducer and activator of transcription 6
chrM_+_11736 0.08 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr13_-_110784209 0.07 ENSRNOT00000071698
TNF receptor-associated factor 5
chr3_+_121596791 0.07 ENSRNOT00000024694
tubulin tyrosine ligase
chr2_+_66940057 0.07 ENSRNOT00000043050
cadherin 9
chr14_-_71973419 0.07 ENSRNOT00000079895
coiled-coil and C2 domain containing 2A
chr11_+_57207656 0.07 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr14_-_46153212 0.06 ENSRNOT00000079269
NACHT and WD repeat domain containing 2
chr2_+_196594303 0.06 ENSRNOT00000064442
ENSRNOT00000044738
aryl hydrocarbon receptor nuclear translocator
chr12_-_10391270 0.06 ENSRNOT00000092340
WAS protein family, member 3
chr1_+_65522118 0.06 ENSRNOT00000058563
myeloid zinc finger 1
chrX_+_984798 0.06 ENSRNOT00000073016
zinc finger protein 182
chr15_+_19547871 0.06 ENSRNOT00000036235
G protein-coupled receptor 137C
chrX_+_128416722 0.06 ENSRNOT00000009336
ENSRNOT00000085110
X-linked inhibitor of apoptosis
chr4_-_183293999 0.06 ENSRNOT00000079695
importin 8
chr18_+_15856801 0.06 ENSRNOT00000071548
zinc finger protein 397
chr10_-_62814520 0.05 ENSRNOT00000019410
slingshot protein phosphatase 2
chr10_+_57218087 0.05 ENSRNOT00000089853
misshapen-like kinase 1
chrX_+_22302703 0.05 ENSRNOT00000078617
ENSRNOT00000086952
lysine demethylase 5C
chr16_+_72268943 0.05 ENSRNOT00000032116
indoleamine 2,3-dioxygenase 2
chr4_+_9981958 0.05 ENSRNOT00000015322
N-acyl phosphatidylethanolamine phospholipase D
chr1_+_224998172 0.05 ENSRNOT00000026321
zinc finger and BTB domain containing 3
chr17_-_27602934 0.05 ENSRNOT00000079298
ras responsive element binding protein 1
chrX_+_22302485 0.05 ENSRNOT00000082902
lysine demethylase 5C
chr16_+_10727571 0.05 ENSRNOT00000084422
multimerin 2
chr17_-_28191436 0.05 ENSRNOT00000000149
lymphocyte antigen 86
chr3_-_21684132 0.05 ENSRNOT00000012364
zinc finger and BTB domain containing 6
chr2_+_113984824 0.04 ENSRNOT00000086399
TRAF2 and NCK interacting kinase
chr18_+_30496318 0.04 ENSRNOT00000027179
protocadherin beta 11
chr6_-_114476723 0.04 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chrX_+_68771100 0.04 ENSRNOT00000043872
StAR-related lipid transfer domain containing 8
chr4_+_87026530 0.04 ENSRNOT00000018425
AVL9 cell migration associated
chr14_+_37919233 0.04 ENSRNOT00000003125
tec protein tyrosine kinase
chr18_+_30909490 0.04 ENSRNOT00000026967
protocadherin gamma subfamily B, 8
chr2_+_93520734 0.04 ENSRNOT00000083909
sorting nexin 16
chr7_+_97760134 0.04 ENSRNOT00000086792
TBC1 domain family, member 31
chr12_+_31536951 0.04 ENSRNOT00000086078
RIMS binding protein 2
chr9_+_49837868 0.04 ENSRNOT00000021999
G protein-coupled receptor 45
chr20_+_6211420 0.03 ENSRNOT00000000624
potassium channel tetramerization domain containing 20
chr6_-_91581262 0.03 ENSRNOT00000034507

chr15_-_33250546 0.03 ENSRNOT00000017857
similar to RIKEN cDNA 4931414P19
chr6_-_91676344 0.03 ENSRNOT00000083872
nuclear export mediator factor
chr1_-_275882444 0.03 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr7_-_129919946 0.03 ENSRNOT00000079976

chr1_+_239412884 0.03 ENSRNOT00000067384
transmembrane protein 2
chr12_-_12945192 0.03 ENSRNOT00000082529
cytohesin 3
chr1_-_80594136 0.03 ENSRNOT00000024800
apolipoprotein C2
chr14_-_16903242 0.03 ENSRNOT00000003001
shroom family member 3
chr1_-_87777668 0.03 ENSRNOT00000037288

chr4_-_117589464 0.03 ENSRNOT00000021167
N-acetyltransferase 8 (GCN5-related) family member 1
chr3_+_130008885 0.03 ENSRNOT00000070972
SLX4 interacting protein
chr7_-_106753592 0.03 ENSRNOT00000006930
potassium voltage-gated channel subfamily Q member 3
chr17_+_44758460 0.03 ENSRNOT00000089436
histone cluster 1, H2an
chr9_+_12114977 0.03 ENSRNOT00000073673

chr13_-_39643361 0.03 ENSRNOT00000003527
dipeptidylpeptidase 10
chr3_-_152259156 0.03 ENSRNOT00000065729
RNA-binding protein 39-like
chrX_-_56765893 0.03 ENSRNOT00000076283
interleukin 1 receptor accessory protein-like 1
chr5_+_139385429 0.03 ENSRNOT00000078622
sex comb on midleg homolog 1 (Drosophila)
chrX_+_123751089 0.03 ENSRNOT00000092384
NFKB activating protein
chr2_-_106703401 0.02 ENSRNOT00000043933

chr18_+_40883224 0.02 ENSRNOT00000039733
laeverin
chr19_+_37252843 0.02 ENSRNOT00000021145
E2F transcription factor 4
chr3_-_151724654 0.02 ENSRNOT00000026964
RNA binding motif protein 39
chr13_-_25652473 0.02 ENSRNOT00000020752
phosphatidylinositol glycan anchor biosynthesis, class N
chr14_+_7630482 0.02 ENSRNOT00000091581
similar to hypothetical protein MGC26744
chr2_+_102685513 0.02 ENSRNOT00000033940
basic helix-loop-helix family, member e22
chr15_-_52029816 0.02 ENSRNOT00000013067
solute carrier family 39 member 14
chr1_+_69853553 0.02 ENSRNOT00000042086
zinc finger protein 954
chr7_+_123963381 0.02 ENSRNOT00000036586
serine hydrolase-like 2
chr1_-_90035522 0.02 ENSRNOT00000028672
ubiquitin-like modifier activating enzyme 2
chr1_-_127292090 0.02 ENSRNOT00000016959
leucine-rich repeat kinase 1
chr1_-_214414763 0.02 ENSRNOT00000025240
ENSRNOT00000077776
mitochondrial glutamate carrier 1-like
chr9_-_9865920 0.02 ENSRNOT00000071068
BRCA1/BRCA2-containing complex, subunit 3
chr8_-_116855062 0.02 ENSRNOT00000050344
ring finger protein 123
chr8_+_82038967 0.02 ENSRNOT00000079535
myosin VA
chr9_-_65442257 0.02 ENSRNOT00000037660
family with sequence similarity 126, member B
chr2_-_30791221 0.02 ENSRNOT00000082846
cyclin B1
chr14_+_45033309 0.02 ENSRNOT00000002933
toll-like receptor 6
chr8_-_57830504 0.02 ENSRNOT00000017683
DEAD-box helicase 10
chr11_+_43194348 0.02 ENSRNOT00000075303
olfactory receptor 1532
chr5_+_128083118 0.02 ENSRNOT00000079161
zinc finger CCHC-type containing 11
chr8_+_93439648 0.02 ENSRNOT00000043008
ribosomal protein S20-like
chr8_+_117280705 0.02 ENSRNOT00000085038
ubiquitin specific peptidase 19
chr1_-_201942344 0.02 ENSRNOT00000027956
similar to RIKEN cDNA 2310057M21
chr3_-_57607683 0.01 ENSRNOT00000093222
ENSRNOT00000058524
methyltransferase like 8
chr3_+_111826297 0.01 ENSRNOT00000081897
phospholipase A2 group IVB
chr10_+_45258887 0.01 ENSRNOT00000048642
butyrophilin like 10
chr3_+_67870111 0.01 ENSRNOT00000012628
nucleoporin 35
chr12_-_24724997 0.01 ENSRNOT00000025560
abhydrolase domain containing 11
chr1_-_217620420 0.01 ENSRNOT00000092783
cortactin
chr10_-_90569575 0.01 ENSRNOT00000074987

chr13_-_83202864 0.01 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr18_+_36829062 0.01 ENSRNOT00000025467
ENSRNOT00000086979
transcription elongation regulator 1
chr7_-_70467915 0.01 ENSRNOT00000088995
solute carrier family 26, member 10
chr4_+_145195070 0.01 ENSRNOT00000010723
myotubularin related protein 14
chr11_+_64522130 0.01 ENSRNOT00000004315
uroplakin 1B
chr5_+_6373583 0.01 ENSRNOT00000084749

chr1_-_155955173 0.01 ENSRNOT00000079345

chr8_-_104995725 0.01 ENSRNOT00000037120
solute carrier family 25 member 36
chr5_+_156396695 0.01 ENSRNOT00000067631
eukaryotic translation initiation factor 4 gamma, 3
chr6_+_26836216 0.01 ENSRNOT00000077903
ENSRNOT00000011373
oligosaccharyltransferase complex subunit 4, non-catalytic
chr1_+_80954858 0.01 ENSRNOT00000030440
zinc finger protein 112
chr9_-_71798265 0.01 ENSRNOT00000043766
crystallin, gamma B
chr7_+_121350965 0.01 ENSRNOT00000092614
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr5_+_61474000 0.01 ENSRNOT00000013930
coiled-coil domain containing 180
chr7_-_111722964 0.01 ENSRNOT00000041802
ribosomal protein S19-like 1
chr14_+_36071376 0.01 ENSRNOT00000082183
ligand of numb-protein X 1
chr1_+_260153645 0.01 ENSRNOT00000054717
zinc finger protein 518A
chr7_-_3229167 0.01 ENSRNOT00000008929
transmembrane protein 198b
chr3_+_118430511 0.01 ENSRNOT00000012966
DTW domain containing 1
chr11_+_31806618 0.01 ENSRNOT00000043410
ENSRNOT00000002769
Son DNA binding protein
chr8_-_62410338 0.01 ENSRNOT00000026358
c-src tyrosine kinase
chrM_+_9870 0.01 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr7_-_124020574 0.01 ENSRNOT00000055988
DNA polymerase delta interacting protein 3
chr7_-_62162453 0.01 ENSRNOT00000010720
cullin-associated and neddylation-dissociated 1
chr3_+_80362858 0.01 ENSRNOT00000021353
ENSRNOT00000086242
LDL receptor related protein 4
chr3_-_93693690 0.01 ENSRNOT00000086745
N-acetyltransferase 10
chr12_-_8418966 0.01 ENSRNOT00000085869
microtubule associated tumor suppressor candidate 2
chr1_-_166919302 0.01 ENSRNOT00000026925
folate receptor beta
chr8_+_116336441 0.01 ENSRNOT00000090123
ENSRNOT00000021590
N-acetyltransferase 6
hyaluronoglucosaminidase 3
chr17_-_19703681 0.01 ENSRNOT00000024021
myosin regulatory light chain interacting protein
chr20_-_14573519 0.01 ENSRNOT00000001772
RAB36, member RAS oncogene family
chr6_+_92864123 0.00 ENSRNOT00000087540
thioredoxin-related transmembrane protein 1
chr4_+_144985880 0.00 ENSRNOT00000009464
THUMP domain containing 3
chr19_+_43251539 0.00 ENSRNOT00000024793
DEAD-box helicase 19A
chr20_-_4391402 0.00 ENSRNOT00000090518
ENSRNOT00000083489
palmitoyl-protein thioesterase 2
chr3_+_125320680 0.00 ENSRNOT00000028891
hypothetical protein LOC681292
chr3_-_113445435 0.00 ENSRNOT00000021562
microfibrillar-associated protein 1A
chrM_+_10160 0.00 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chr9_-_94192813 0.00 ENSRNOT00000025978
alkaline phosphatase, placental
chr8_-_117820413 0.00 ENSRNOT00000075819
translation machinery associated 7 homolog
chr5_+_70528688 0.00 ENSRNOT00000036799
fukutin
chr6_-_104409005 0.00 ENSRNOT00000040965
coiled-coil domain containing 177
chr1_-_228263198 0.00 ENSRNOT00000028572
olfactory receptor 1874
chr10_-_76039964 0.00 ENSRNOT00000003164
musashi RNA-binding protein 2
chr14_+_3882398 0.00 ENSRNOT00000033794
HFM1, ATP-dependent DNA helicase homolog
chr1_-_47331412 0.00 ENSRNOT00000046746
ezrin
chrM_-_14061 0.00 ENSRNOT00000051268
mitochondrially encoded NADH dehydrogenase 6
chr13_+_94888078 0.00 ENSRNOT00000077995
ENSRNOT00000005647
ENSRNOT00000077345
serologically defined colon cancer antigen 8
chr5_-_150609352 0.00 ENSRNOT00000074374
phosphatase and actin regulator 4
chr2_+_240642184 0.00 ENSRNOT00000083181
ubiquitin-conjugating enzyme E2D 3
chrX_-_17252877 0.00 ENSRNOT00000060213
retinitis pigmentosa 1-like 1 protein-like
chr12_-_41497610 0.00 ENSRNOT00000001860
IQ motif containing D

Network of associatons between targets according to the STRING database.

First level regulatory network of Otx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)