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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Osr2_Osr1
Z-value: 0.55
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Transcription factors associated with Osr2_Osr1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Osr1 | rn6_v1_chr6_+_35314444_35314444 | -0.72 | 1.7e-01 | Click! |
| Osr2 | rn6_v1_chr7_+_74047814_74047814 | -0.26 | 6.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_48319522 Show fit | 0.25 |
ENSRNOT00000080281
|
|
|
| chr4_-_181486090 Show fit | 0.25 |
ENSRNOT00000075453
|
|
|
| chr8_+_48571323 Show fit | 0.23 |
ENSRNOT00000059776
|
coiled-coil domain containing 153 |
|
| chr1_+_77782825 Show fit | 0.22 |
ENSRNOT00000058230
|
|
|
| chr2_-_256154584 Show fit | 0.13 |
ENSRNOT00000072487
|
|
|
| chr10_-_70788309 Show fit | 0.13 |
ENSRNOT00000029184
|
chemokine (C-C motif) ligand 9 |
|
| chr1_-_219438779 Show fit | 0.12 |
ENSRNOT00000029237
|
TBC1 domain family, member 10C |
|
| chr11_+_67555658 Show fit | 0.10 |
ENSRNOT00000039075
|
cystatin A (stefin A) |
|
| chr14_-_114047527 Show fit | 0.10 |
ENSRNOT00000083199
|
|
|
| chr1_-_164205222 Show fit | 0.10 |
ENSRNOT00000035774
|
monoacylglycerol O-acyltransferase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Osr2_Osr1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.0 | 0.1 | GO:0032759 | TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) |
| 0.0 | 0.1 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.1 | GO:0046015 | regulation of transcription by glucose(GO:0046015) |
| 0.0 | 0.0 | GO:0006288 | base-excision repair, DNA ligation(GO:0006288) |
| 0.0 | 0.0 | GO:0051867 | general adaptation syndrome, behavioral process(GO:0051867) |
| 0.0 | 0.0 | GO:0035625 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 0.0 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.1 | GO:0044302 | dentate gyrus mossy fiber(GO:0044302) |
| 0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.0 | GO:0070421 | DNA ligase III-XRCC1 complex(GO:0070421) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.0 | 0.1 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.0 | 0.0 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |