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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Osr2_Osr1

Z-value: 0.55

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Transcription factors associated with Osr2_Osr1

Gene Symbol Gene ID Gene Info
ENSRNOG00000011136 odd-skipped related transciption factor 2
ENSRNOG00000004210 odd-skipped related transciption factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Osr1rn6_v1_chr6_+_35314444_35314444-0.721.7e-01Click!
Osr2rn6_v1_chr7_+_74047814_74047814-0.266.7e-01Click!

Activity profile of Osr2_Osr1 motif

Sorted Z-values of Osr2_Osr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_48319522 0.25 ENSRNOT00000080281

chr4_-_181486090 0.25 ENSRNOT00000075453

chr8_+_48571323 0.23 ENSRNOT00000059776
coiled-coil domain containing 153
chr1_+_77782825 0.22 ENSRNOT00000058230

chr2_-_256154584 0.13 ENSRNOT00000072487

chr10_-_70788309 0.13 ENSRNOT00000029184
chemokine (C-C motif) ligand 9
chr1_-_219438779 0.12 ENSRNOT00000029237
TBC1 domain family, member 10C
chr11_+_67555658 0.10 ENSRNOT00000039075
cystatin A (stefin A)
chr14_-_114047527 0.10 ENSRNOT00000083199

chr1_-_164205222 0.10 ENSRNOT00000035774
monoacylglycerol O-acyltransferase 2
chr3_-_151724654 0.10 ENSRNOT00000026964
RNA binding motif protein 39
chr9_+_66889028 0.09 ENSRNOT00000087194
calcium responsive transcription factor
chr10_-_94500591 0.09 ENSRNOT00000015976
CD79b molecule
chr14_-_81339526 0.09 ENSRNOT00000015894
G protein-coupled receptor kinase 4
chr1_-_170578693 0.08 ENSRNOT00000025651
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr8_-_55491152 0.08 ENSRNOT00000014965
rCG58364-like
chr1_+_154131926 0.08 ENSRNOT00000035257
ferritin light chain 1-like
chr5_-_2803855 0.08 ENSRNOT00000009490
ribosomal protein S8-like
chr5_+_74649765 0.08 ENSRNOT00000075952
paralemmin 2
chr19_-_39267928 0.07 ENSRNOT00000027686
transmembrane p24 trafficking protein 6
chr2_-_35104963 0.07 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr3_+_122816924 0.07 ENSRNOT00000045604
similar to ribosomal protein L31
chr2_+_58724855 0.07 ENSRNOT00000089609
calcyphosine-like
chr16_-_69280109 0.07 ENSRNOT00000058595

chr6_+_127333590 0.07 ENSRNOT00000063970
interferon, alpha-inducible protein 27
chr1_+_61522298 0.06 ENSRNOT00000029111
zinc finger protein 51
chr1_-_167884690 0.06 ENSRNOT00000091372
olfactory receptor 61
chr18_+_62805410 0.06 ENSRNOT00000086679
G protein subunit alpha L
chr6_+_137953545 0.06 ENSRNOT00000006804
cysteine-rich protein 2
chr7_+_144605058 0.06 ENSRNOT00000031404
homeobox C8
chr8_+_132869712 0.06 ENSRNOT00000008294
C-X-C motif chemokine receptor 6
chr11_-_31892531 0.05 ENSRNOT00000033745
crystallin zeta like 1
chr10_+_68173369 0.05 ENSRNOT00000037072
transmembrane protein 98
chr2_+_147496229 0.05 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr5_-_163231494 0.05 ENSRNOT00000085929
ENSRNOT00000022968
TNF receptor superfamily member 8
chr5_+_154310453 0.05 ENSRNOT00000013322
UDP-galactose-4-epimerase
chr1_+_166564664 0.05 ENSRNOT00000090959
phosphodiesterase 2A
chr10_+_70153427 0.05 ENSRNOT00000076703
DNA ligase 3
chr11_+_38727048 0.05 ENSRNOT00000081537
zinc finger protein 260-like
chr7_-_59139910 0.05 ENSRNOT00000032374
RIKEN cDNA 4933416C03 gene
chrX_+_1543244 0.05 ENSRNOT00000071634

chr4_-_178441547 0.05 ENSRNOT00000087434
ENSRNOT00000055542
SRY box 5
chr14_-_6587141 0.05 ENSRNOT00000061664
similar to THO complex subunit 2 (Tho2)
chr3_+_119805941 0.05 ENSRNOT00000018584
adrenoceptor alpha 2B
chr6_+_144291974 0.05 ENSRNOT00000035255
non-SMC condensin II complex, subunit G2
chr7_-_145154131 0.05 ENSRNOT00000055271
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr2_-_192671059 0.04 ENSRNOT00000012174
small proline-rich protein 1A
chr5_-_17061361 0.04 ENSRNOT00000089318
proenkephalin
chr10_+_86223336 0.04 ENSRNOT00000038939
hippyragranin
chr17_-_14687408 0.04 ENSRNOT00000088542

chr15_-_40545824 0.04 ENSRNOT00000017204
nucleoporin 58
chr10_+_95242986 0.04 ENSRNOT00000065589
ENSRNOT00000080460
similar to hypothetical protein LOC284018 isoform b
chr1_-_143169657 0.04 ENSRNOT00000025888
ribosomal protein S17
chr6_-_33088582 0.04 ENSRNOT00000083144
tudor domain containing 15
chrX_+_123350346 0.04 ENSRNOT00000017026
solute carrier family 25, member 43
chr3_+_138597638 0.04 ENSRNOT00000031623
zinc finger protein 133
chr1_-_250626844 0.04 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr20_-_31736212 0.04 ENSRNOT00000000662
similar to RIKEN cDNA 2010107G23
chr15_+_105640097 0.04 ENSRNOT00000014300
muscleblind-like splicing regulator 2
chr15_-_60289763 0.04 ENSRNOT00000038579
family with sequence similarity 216, member B
chr8_+_50200069 0.04 ENSRNOT00000023677
proprotein convertase subtilisin/kexin type 7
chr8_+_107875991 0.04 ENSRNOT00000090299
DAZ interacting zinc finger protein 1-like
chr2_+_4942775 0.04 ENSRNOT00000093548
ENSRNOT00000093741
family with sequence similarity 172, member A
chrM_+_8599 0.03 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr7_+_26375866 0.03 ENSRNOT00000059639
aldehyde dehydrogenase 1 family, member L2
chr9_+_67774150 0.03 ENSRNOT00000091060
inducible T-cell co-stimulator
chr2_-_45077219 0.03 ENSRNOT00000014319
granzyme K
chr5_+_18901039 0.03 ENSRNOT00000012066
family with sequence similarity 110, member B
chr2_+_187218851 0.03 ENSRNOT00000017798
SH2 domain containing 2A
chr2_-_26011429 0.03 ENSRNOT00000065143
Rho guanine nucleotide exchange factor 28
chr10_-_56276764 0.03 ENSRNOT00000049048
eukaryotic translation initiation factor 4A1
chr1_-_80483487 0.03 ENSRNOT00000074418
gem (nuclear organelle) associated protein 7
chr10_+_3411380 0.03 ENSRNOT00000004346
similar to RIKEN cDNA 2900011O08
chr14_+_19319299 0.03 ENSRNOT00000086542
ankyrin repeat domain 17
chr1_+_99706780 0.03 ENSRNOT00000024758
kallikrein related-peptidase 12
chr14_+_71533460 0.03 ENSRNOT00000084274
prominin 1
chr8_-_64800467 0.03 ENSRNOT00000073122
nuclear receptor subfamily 2, group E, member 3
chr17_+_69634890 0.03 ENSRNOT00000029049
aldo-keto reductase family 1, member C13
chr1_-_167893061 0.03 ENSRNOT00000049401
olfactory receptor 60
chr16_-_20864176 0.03 ENSRNOT00000092706
coatomer protein complex, subunit epsilon
chr20_-_11528332 0.03 ENSRNOT00000038419
thrombospondin-type laminin G domain and EAR repeats
chr9_-_99818262 0.03 ENSRNOT00000056600
COP9 signalosome subunit 9
chr4_-_121565212 0.03 ENSRNOT00000088753
coiled-coil-helix-coiled-coil-helix domain containing 6
chr4_+_57855416 0.03 ENSRNOT00000029608
carboxypeptidase A2
chr3_+_113976687 0.03 ENSRNOT00000022437
eukaryotic translation initiation factor 3, subunit J
chr8_-_36467627 0.03 ENSRNOT00000082346
family with sequence similarity 118, member B
chr4_-_181348038 0.03 ENSRNOT00000082879
hypothetical protein LOC690783
chr10_+_7041510 0.03 ENSRNOT00000003514
calcium regulated heat stable protein 1
chr8_+_72029489 0.03 ENSRNOT00000089336
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr18_-_58423196 0.03 ENSRNOT00000025556
piezo-type mechanosensitive ion channel component 2
chr15_-_100348760 0.03 ENSRNOT00000085607

chr12_-_30491102 0.03 ENSRNOT00000001224
sulfatase modifying factor 2
chr11_+_82862695 0.03 ENSRNOT00000071707
ENSRNOT00000073435
chloride voltage-gated channel 2
chr11_-_27080701 0.03 ENSRNOT00000002180
listerin E3 ubiquitin protein ligase 1
chr11_+_83883879 0.03 ENSRNOT00000050927
chloride channel protein 2
chr7_-_102298522 0.03 ENSRNOT00000006273
alpha-1-B glycoprotein
chrX_+_53053609 0.03 ENSRNOT00000058357
dystrophin
chr5_+_70592871 0.02 ENSRNOT00000035687
TAL bHLH transcription factor 2
chr10_-_109278510 0.02 ENSRNOT00000038993
TEPSIN, adaptor related protein complex 4 accessory protein
chr1_-_212568224 0.02 ENSRNOT00000024976
fucose mutarotase-like
chr18_-_48384645 0.02 ENSRNOT00000023485
peptidylprolyl isomerase C
chr1_-_53087474 0.02 ENSRNOT00000017302
C-C motif chemokine receptor 6
chr1_+_163398891 0.02 ENSRNOT00000020513
guanylate cyclase 2E
chr4_+_68849033 0.02 ENSRNOT00000016912
maltase-glucoamylase
chr16_+_10277775 0.02 ENSRNOT00000090679
retinol binding protein 3
chr5_+_8876044 0.02 ENSRNOT00000008877
COP9 signalosome subunit 5
chr1_-_163148948 0.02 ENSRNOT00000046850
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
chr9_+_98113346 0.02 ENSRNOT00000026912
prolactin releasing hormone
chr1_-_260460791 0.02 ENSRNOT00000018179
tolloid-like 2
chrX_-_15761932 0.02 ENSRNOT00000015641
ENSRNOT00000091146
forkhead box P3
chr1_+_101610773 0.02 ENSRNOT00000032535
Ras interacting protein 1
chr8_+_115131367 0.02 ENSRNOT00000014849
ribosomal protein L29
chr14_+_84482674 0.02 ENSRNOT00000009313
leukemia inhibitory factor
chr10_-_15282951 0.02 ENSRNOT00000027266
Rab40c, member RAS oncogene family
chr14_+_2050483 0.02 ENSRNOT00000000047
solute carrier family 26 member 1
chr2_+_247299433 0.02 ENSRNOT00000050330
unc-5 netrin receptor C
chr1_+_260153645 0.02 ENSRNOT00000054717
zinc finger protein 518A
chr17_+_44522140 0.02 ENSRNOT00000080490
histone H4 variant H4-v.1
chr4_-_163157744 0.02 ENSRNOT00000089712
C-type lectin domain family 12, member B
chr15_-_18675431 0.02 ENSRNOT00000080794
abhydrolase domain containing 6
chr7_+_64987859 0.02 ENSRNOT00000005694
transmembrane BAX inhibitor motif containing 4
chr4_-_133127175 0.02 ENSRNOT00000057758
SHQ1, H/ACA ribonucleoprotein assembly factor
chr11_-_1819094 0.02 ENSRNOT00000000911
similar to 4930453N24Rik protein
chr3_+_170252901 0.02 ENSRNOT00000005871
melanocortin 3 receptor
chr7_-_36408588 0.02 ENSRNOT00000063946
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_+_137386422 0.02 ENSRNOT00000018568
LOC362793
chr11_+_83884048 0.02 ENSRNOT00000002376
chloride channel protein 2
chr4_-_50200328 0.02 ENSRNOT00000060530
aminoadipate-semialdehyde synthase
chr1_+_141832774 0.02 ENSRNOT00000073302
fucose mutarotase
chr12_+_42097626 0.02 ENSRNOT00000001893
T-box 5
chr8_-_112807598 0.02 ENSRNOT00000015344
DnaJ heat shock protein family (Hsp40) member C13
chr3_-_152259156 0.02 ENSRNOT00000065729
RNA-binding protein 39-like
chr9_-_11080155 0.02 ENSRNOT00000072830
fibronectin type III and SPRY domain containing 1
chr10_-_56850085 0.02 ENSRNOT00000025767
ribonuclease K
chr19_-_53477420 0.02 ENSRNOT00000071344
hypothetical protein LOC687560
chr10_+_15697227 0.02 ENSRNOT00000028008
interleukin 9 receptor
chr1_-_240601744 0.02 ENSRNOT00000024093
aldehyde dehydrogenase family 1, subfamily A7
chr3_-_150412179 0.02 ENSRNOT00000023786
eukaryotic translation initiation factor 2 subunit beta
chr12_-_19439977 0.02 ENSRNOT00000060035
neurexophilin and PC-esterase domain family, member 5
chr15_+_18451144 0.01 ENSRNOT00000010260
acyl-CoA oxidase 2
chr6_-_11274932 0.01 ENSRNOT00000021538
mutS homolog 2
chr18_+_59748444 0.01 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr16_-_76110553 0.01 ENSRNOT00000043384
microcephalin 1
chr2_+_196655469 0.01 ENSRNOT00000028730
cathepsin K
chr15_-_51400606 0.01 ENSRNOT00000023318
charged multivesicular body protein 7
chr12_+_19513100 0.01 ENSRNOT00000030161
similar to family with sequence similarity 55, member C
chr12_-_19440501 0.01 ENSRNOT00000060048
neurexophilin and PC-esterase domain family, member 5
chr12_+_52397792 0.01 ENSRNOT00000085661
ENSRNOT00000056694
ENSRNOT00000056693
ENSRNOT00000056692
ENSRNOT00000081447
purinergic receptor P2X 2
chr4_+_38255413 0.01 ENSRNOT00000089897
PHD finger protein 14
chr4_-_121684264 0.01 ENSRNOT00000083168
vomeronasal 1 receptor 90
chr3_-_13865843 0.01 ENSRNOT00000025194
Rab9 effector protein with kelch motifs
chr9_+_90857308 0.01 ENSRNOT00000073993
collagen alpha-3(IV) chain-like
chrX_+_156355376 0.01 ENSRNOT00000078304
L antigen family, member 3
chr10_-_59049482 0.01 ENSRNOT00000078272
spinster homolog 2
chr10_-_16731898 0.01 ENSRNOT00000028186
CREB3 regulatory factor
chr13_+_106751625 0.01 ENSRNOT00000004992
usherin
chr1_+_91363492 0.01 ENSRNOT00000014517
CCAAT/enhancer binding protein alpha
chr7_-_57816621 0.01 ENSRNOT00000090748

chr1_+_170578889 0.01 ENSRNOT00000025906
integrin-linked kinase
chr20_-_32076503 0.01 ENSRNOT00000000441
Suv3 like RNA helicase
chr1_-_78573374 0.01 ENSRNOT00000090519
Rho GTPase activating protein 35
chr3_+_72395218 0.01 ENSRNOT00000057616
proteoglycan 3, pro eosinophil major basic protein 2
chr5_+_64053946 0.01 ENSRNOT00000011622
inversin
chrX_+_68626185 0.01 ENSRNOT00000090942
Yip1 domain family, member 6
chr8_-_45137893 0.01 ENSRNOT00000010743
similar to hypothetical protein FLJ23554
chr1_-_128604188 0.01 ENSRNOT00000033858
leucine rich repeat containing 28
chr6_+_8284878 0.01 ENSRNOT00000009581
solute carrier family 3 member 1
chr4_-_62663200 0.01 ENSRNOT00000040969
CCR4-NOT transcription complex, subunit 4
chr10_-_56849255 0.01 ENSRNOT00000025491
similar to RIKEN cDNA 1110020A23
chr1_-_91588609 0.01 ENSRNOT00000050931
small nuclear ribonucleoprotein polypeptide G
chr2_-_149325913 0.01 ENSRNOT00000036690
G protein-coupled receptor 171
chrX_-_77956352 0.01 ENSRNOT00000003296
zinc finger CCHC-type containing 5
chr11_+_34316295 0.01 ENSRNOT00000081834
single-minded family bHLH transcription factor 2
chr2_+_237679792 0.01 ENSRNOT00000064628
GIMAP family P-loop NTPase domain containing 1
chr2_-_5577369 0.01 ENSRNOT00000093420
nuclear receptor subfamily 2, group F, member 1
chr13_+_101698096 0.01 ENSRNOT00000089309
axin interactor, dorsalization associated
chr1_-_73682247 0.01 ENSRNOT00000079498
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr19_-_29802083 0.01 ENSRNOT00000024755

chr1_+_70222964 0.01 ENSRNOT00000050180
paternally expressed 3
chr15_+_344685 0.01 ENSRNOT00000065542
ENSRNOT00000066928
potassium calcium-activated channel subfamily M alpha 1
chr9_-_11027506 0.01 ENSRNOT00000071107
chromatin assembly factor 1 subunit A
chr1_+_218532045 0.01 ENSRNOT00000018848
mitochondrial ribosomal protein L21
chr3_+_72134731 0.01 ENSRNOT00000083592
yippee-like 4
chr7_+_37101391 0.01 ENSRNOT00000029764
early endosome antigen 1
chr2_-_80408672 0.01 ENSRNOT00000067638
family with sequence similarity 105, member A
chr10_+_34383396 0.01 ENSRNOT00000047186
olfactory receptor 1386
chr10_+_11240138 0.01 ENSRNOT00000048687
sarcalumenin
chr2_-_188736462 0.01 ENSRNOT00000028030
flavin adenine dinucleotide synthetase 1
chrX_-_83151511 0.01 ENSRNOT00000057378
highly divergent homeobox
chr17_-_10061750 0.01 ENSRNOT00000082042
ENSRNOT00000022646
zinc finger protein 346
chr11_+_71222600 0.01 ENSRNOT00000002418
mucin 20, cell surface associated
chr16_+_53998560 0.01 ENSRNOT00000077188
ENSRNOT00000013463
N-acylsphingosine amidohydrolase 1
chrX_-_75566481 0.01 ENSRNOT00000003714
zinc finger, DHHC-type containing 15
chr2_+_45104305 0.01 ENSRNOT00000014559
endothelial cell-specific molecule 1
chr8_-_50199978 0.01 ENSRNOT00000023459
ring finger protein 214
chr6_+_128738388 0.01 ENSRNOT00000050204
ribosomal protein L6, pseudogene 1
chr18_-_27395603 0.01 ENSRNOT00000034385
rCG49431-like
chr12_-_52396066 0.01 ENSRNOT00000056712
leucine rich colipase-like 1
chr1_-_142183884 0.01 ENSRNOT00000016032
FES proto-oncogene, tyrosine kinase
chr2_-_139528162 0.01 ENSRNOT00000014317
solute carrier family 7 member 11

Network of associatons between targets according to the STRING database.

First level regulatory network of Osr2_Osr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.0 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.0 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.0 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.0 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway