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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Onecut2_Onecut3

Z-value: 0.23

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Transcription factors associated with Onecut2_Onecut3

Gene Symbol Gene ID Gene Info
ENSRNOG00000052665 one cut domain, family member 2
ENSRNOG00000059889 one cut domain, family member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Onecut3rn6_v1_chr7_-_12085226_120852260.711.8e-01Click!
Onecut2rn6_v1_chr18_+_59830363_59830422-0.365.5e-01Click!

Activity profile of Onecut2_Onecut3 motif

Sorted Z-values of Onecut2_Onecut3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_190370499 0.26 ENSRNOT00000084389

chr10_+_61685645 0.15 ENSRNOT00000003933
MAX network transcriptional repressor
chr2_+_27905535 0.13 ENSRNOT00000022120
family with sequence similarity 169, member A
chr5_-_153840178 0.11 ENSRNOT00000025075
NIPA-like domain containing 3
chr5_-_168734296 0.10 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr5_-_127878792 0.09 ENSRNOT00000014436
zyg-11 family member B, cell cycle regulator
chr7_+_34533543 0.09 ENSRNOT00000007412
ENSRNOT00000084185
netrin 4
chr10_+_35343189 0.08 ENSRNOT00000083688
mitogen-activated protein kinase 9
chr18_-_77579969 0.08 ENSRNOT00000034896
spalt-like transcription factor 3
chr1_-_124803363 0.08 ENSRNOT00000066380
Kruppel-like factor 13
chr16_+_85331866 0.07 ENSRNOT00000019615
DNA ligase 4
chr7_-_114848414 0.07 ENSRNOT00000032620
solute carrier family 45, member 4
chr5_+_76092287 0.06 ENSRNOT00000020207
zinc finger protein 483
chr13_-_73055631 0.06 ENSRNOT00000081892
xenotropic and polytropic retrovirus receptor 1
chr2_-_39007976 0.06 ENSRNOT00000064292
zinc finger, SWIM-type containing 6
chr9_-_17880706 0.06 ENSRNOT00000031549
alanyl-tRNA synthetase 2, mitochondrial
chr7_+_3216497 0.06 ENSRNOT00000008909
matrix metallopeptidase 19
chr13_+_82231030 0.06 ENSRNOT00000003551
SCY1 like pseudokinase 3
chr5_-_105579959 0.06 ENSRNOT00000010827
solute carrier family 24 member 2
chr1_-_175657485 0.05 ENSRNOT00000024561
ring finger protein 141
chr10_+_32824 0.05 ENSRNOT00000077828
meiosis arrest female protein 1-like
chr2_-_231409496 0.05 ENSRNOT00000055615
ENSRNOT00000015386
ENSRNOT00000068415
ankyrin 2
chr8_+_76754492 0.05 ENSRNOT00000085727
myosin IE
chr7_+_42304534 0.05 ENSRNOT00000085097
KIT ligand
chrX_+_120901495 0.05 ENSRNOT00000040742
WD repeat domain 44
chr10_-_91986632 0.05 ENSRNOT00000087824
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr10_-_27179254 0.05 ENSRNOT00000004619
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr14_-_84751886 0.04 ENSRNOT00000078838
myotubularin related protein 3
chr6_-_41870046 0.04 ENSRNOT00000005863
lipin 1
chr14_-_16903242 0.04 ENSRNOT00000003001
shroom family member 3
chr3_+_79823945 0.04 ENSRNOT00000014484
CUGBP, Elav-like family member 1
chr12_-_45801842 0.04 ENSRNOT00000078837

chr1_-_197568165 0.04 ENSRNOT00000079044
exportin 6
chr10_-_15465404 0.04 ENSRNOT00000077826
ENSRNOT00000027593
2,4-dienoyl-CoA reductase 2
chr3_+_8928534 0.04 ENSRNOT00000088509
ENSRNOT00000065300
mitoguardin 2
chr18_+_30496318 0.04 ENSRNOT00000027179
protocadherin beta 11
chr8_-_22821397 0.04 ENSRNOT00000045488
KN motif and ankyrin repeat domains 2
chr8_-_63750531 0.04 ENSRNOT00000009496
neogenin 1
chr2_+_186980793 0.04 ENSRNOT00000091336
Rho guanine nucleotide exchange factor 11
chr2_+_87018305 0.04 ENSRNOT00000079449
regulator of sex limited protein 1
chr17_-_4454701 0.04 ENSRNOT00000080750
ENSRNOT00000066950
death associated protein kinase 1
chr19_+_39543242 0.04 ENSRNOT00000018837
WW domain containing E3 ubiquitin protein ligase 2
chr1_+_98627372 0.04 ENSRNOT00000030370
zinc finger protein 17
chr5_+_187312 0.04 ENSRNOT00000030857
zinc finger protein 120-like
chr9_+_6970507 0.04 ENSRNOT00000079488
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr13_+_90260783 0.03 ENSRNOT00000050547
CD84 molecule
chr1_+_84685931 0.03 ENSRNOT00000063839
zinc finger protein 780B
chr2_-_196582997 0.03 ENSRNOT00000081672

chr2_+_113007549 0.03 ENSRNOT00000017758
tumor necrosis factor superfamily member 10
chr3_+_11653529 0.03 ENSRNOT00000091048
adenylate kinase 1
chr20_-_31597830 0.03 ENSRNOT00000085877
collagen type XIII alpha 1 chain
chr3_+_67870111 0.03 ENSRNOT00000012628
nucleoporin 35
chr2_+_200603426 0.03 ENSRNOT00000072189
zinc finger protein 697-like
chr3_+_116899878 0.03 ENSRNOT00000090802
ENSRNOT00000066101
semaphorin 6D
chr14_-_104960141 0.03 ENSRNOT00000056944
aftiphilin
chr18_-_37776453 0.03 ENSRNOT00000087876
dihydropyrimidinase-like 3
chr14_-_82171480 0.03 ENSRNOT00000021952
nuclear receptor binding SET domain protein 2
chr15_-_14737704 0.03 ENSRNOT00000011307
synaptoporin
chr2_+_252771017 0.03 ENSRNOT00000075452
ENSRNOT00000055318
tubulin tyrosine ligase like 7
chr1_-_255815733 0.03 ENSRNOT00000047387
cytoplasmic polyadenylation element binding protein 3
chr2_+_86891092 0.03 ENSRNOT00000077162
ENSRNOT00000083066
zinc finger protein 457-like
chr2_+_195996521 0.03 ENSRNOT00000082849
pogo transposable element with ZNF domain
chr2_+_104020955 0.03 ENSRNOT00000045586
mitochondrial fission regulator 1
chr20_-_31598118 0.03 ENSRNOT00000046537
collagen type XIII alpha 1 chain
chr7_-_81592206 0.03 ENSRNOT00000007979
angiopoietin 1
chr1_-_263885169 0.03 ENSRNOT00000030782
conserved helix-loop-helix ubiquitous kinase
chr3_-_83306781 0.03 ENSRNOT00000014088
tetratricopeptide repeat domain 17
chr2_-_57600820 0.03 ENSRNOT00000083247
NIPBL, cohesin loading factor
chr3_-_158328881 0.03 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chrX_-_84821775 0.02 ENSRNOT00000000174
CHM, Rab escort protein 1
chr3_+_129753742 0.02 ENSRNOT00000007998
ENSRNOT00000080581
synaptosomal-associated protein 25
chr5_-_77031120 0.02 ENSRNOT00000022987
INTS3 and NABP interacting protein
chr4_+_64088900 0.02 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr9_-_15274917 0.02 ENSRNOT00000019650
progastricsin
chr14_-_103321270 0.02 ENSRNOT00000006157
Meis homeobox 1
chr10_-_71358190 0.02 ENSRNOT00000078646
uncharacterized LOC102552783
chrX_+_65566047 0.02 ENSRNOT00000092103
hephaestin
chr19_-_38484611 0.02 ENSRNOT00000077960
nuclear factor of activated T-cells 5
chr10_+_80953006 0.02 ENSRNOT00000035567
heterogeneous nuclear ribonucleoprotein A3
chrX_+_6273733 0.02 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr2_+_235596907 0.02 ENSRNOT00000071463
ENSRNOT00000075728
collagen type XXV alpha 1 chain
chr10_+_10808823 0.02 ENSRNOT00000004298
ankyrin repeat and sterile alpha motif domain containing 3
chr2_+_116032455 0.02 ENSRNOT00000066495
polyhomeotic homolog 3
chr15_-_52288893 0.02 ENSRNOT00000016209
family with sequence similarity 160, member B2
chr17_+_8135251 0.02 ENSRNOT00000016982
transient receptor potential cation channel, subfamily C, member 7
chr16_-_10603850 0.02 ENSRNOT00000087737
family with sequence similarity 35, member A
chr2_+_27000327 0.02 ENSRNOT00000087418
POC5 centriolar protein
chr10_+_65767053 0.02 ENSRNOT00000078897
vitronectin
chr1_+_80028928 0.02 ENSRNOT00000012082
F-box protein 46
chr15_-_28746042 0.02 ENSRNOT00000017730
spalt-like transcription factor 2
chr8_-_80631873 0.02 ENSRNOT00000091661
ENSRNOT00000080662
unc-13 homolog C
chr2_-_38110567 0.02 ENSRNOT00000072212
importin 11
chr8_+_70317586 0.02 ENSRNOT00000016260
DENN domain containing 4A
chr10_+_59259955 0.02 ENSRNOT00000021816
ankyrin repeat and FYVE domain containing 1
chrX_+_51286737 0.02 ENSRNOT00000035692
dystrophin
chr10_-_72417070 0.02 ENSRNOT00000036814
ubiquitin specific peptidase 32
chr17_+_15762030 0.02 ENSRNOT00000089310
FYVE, RhoGEF and PH domain containing 3
chr4_-_129515435 0.02 ENSRNOT00000039353
EGF domain specific O-linked N-acetylglucosamine transferase
chr2_+_95008477 0.02 ENSRNOT00000015327
tumor protein D52
chr4_+_147756553 0.02 ENSRNOT00000086549
ENSRNOT00000014733
intraflagellar transport 122
chr1_+_274688580 0.02 ENSRNOT00000020580
SHOC2 leucine-rich repeat scaffold protein
chr5_-_7941822 0.02 ENSRNOT00000079917
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr14_+_108143869 0.01 ENSRNOT00000090003
ubiquitin specific peptidase 34
chr11_+_87522971 0.01 ENSRNOT00000043545
sphingomyelin phosphodiesterase 4
chr19_+_49637016 0.01 ENSRNOT00000016880
beta-carotene oxygenase 1
chr2_+_257626383 0.01 ENSRNOT00000080993
zinc finger, ZZ-type containing 3
chr10_-_57291146 0.01 ENSRNOT00000005653
sperm associated antigen 7
chr8_-_87245951 0.01 ENSRNOT00000015299
transmembrane protein 30A
chr15_-_88670349 0.01 ENSRNOT00000012881
ring finger protein 219
chr19_-_11669578 0.01 ENSRNOT00000026373
G protein subunit alpha o1
chrX_+_84064427 0.01 ENSRNOT00000046364
zinc finger protein 711
chr1_-_141655894 0.01 ENSRNOT00000082591
adaptor-related protein complex 3, sigma 2 subunit
chr5_+_49311030 0.01 ENSRNOT00000010850
cannabinoid receptor 1
chr12_+_47590154 0.01 ENSRNOT00000045946
GIT ArfGAP 2
chr2_-_198852161 0.01 ENSRNOT00000028815
RNA polymerase III subunit C
chr7_+_141642777 0.01 ENSRNOT00000079811

chr6_-_114476723 0.01 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chr14_-_21127868 0.01 ENSRNOT00000020608
ENSRNOT00000092172
RUN and FYVE domain containing 3
chr7_+_142877086 0.01 ENSRNOT00000088730
general receptor for phosphoinositides 1 associated scaffold protein
chrX_+_54266687 0.01 ENSRNOT00000058309
LRRGT00076-like
chr18_+_55505993 0.01 ENSRNOT00000043736
similar to interferon-inducible GTPase
chr4_-_145948996 0.01 ENSRNOT00000043476
ATPase plasma membrane Ca2+ transporting 2
chr3_+_8430829 0.01 ENSRNOT00000090440
ENSRNOT00000060969
cerebral endothelial cell adhesion molecule
chr1_-_53802658 0.01 ENSRNOT00000032667
afadin, adherens junction formation factor
chr18_+_17403407 0.01 ENSRNOT00000045150
similar to KIAA1328 protein
chr3_-_121488540 0.01 ENSRNOT00000023845
zinc finger CCCH type containing 8
chr16_+_8737974 0.01 ENSRNOT00000064255
ERCC excision repair 6, chromatin remodeling factor
chr1_+_73837944 0.01 ENSRNOT00000036413
leukocyte-associated immunoglobulin-like receptor 1
chrX_+_44907521 0.01 ENSRNOT00000004901
transducin (beta)-like 1 X-linked
chr7_-_11699436 0.01 ENSRNOT00000049221
ENSRNOT00000066037
transmembrane protease, serine 9
chr10_+_36589181 0.01 ENSRNOT00000045596
zinc finger protein 354A
chr5_-_33664435 0.01 ENSRNOT00000009047
WW domain containing E3 ubiquitin protein ligase 1
chrX_-_13279082 0.01 ENSRNOT00000051898
ENSRNOT00000060857
tetraspanin 7
chr3_-_90751055 0.01 ENSRNOT00000040741
LRRGT00091
chr20_-_28263037 0.01 ENSRNOT00000030348
ectodysplasin-A receptor
chr8_+_59900651 0.01 ENSRNOT00000020410
transmembrane protein 266
chrX_-_62690806 0.01 ENSRNOT00000018147
DNA polymerase alpha 1, catalytic subunit
chr15_-_33752665 0.01 ENSRNOT00000034102
zinc finger homeobox 2
chr10_-_89130339 0.01 ENSRNOT00000027640
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr19_+_37576075 0.01 ENSRNOT00000089022
family with sequence similarity 65, member A
chr10_-_4910305 0.01 ENSRNOT00000033122
RecQ mediated genome instability 2
chr8_+_117068582 0.01 ENSRNOT00000073559
aminomethyltransferase
chr1_-_102849430 0.01 ENSRNOT00000086856
serum amyloid A4
chrX_+_135092040 0.01 ENSRNOT00000048022
UTP14A small subunit processome component
chr1_+_84758233 0.01 ENSRNOT00000072734

chr8_-_69121192 0.01 ENSRNOT00000012404
zwilch kinetochore protein
chr18_-_74059533 0.01 ENSRNOT00000038767
similar to hypothetical protein
chr10_-_31419235 0.01 ENSRNOT00000059496
cytoplasmic FMR1 interacting protein 2
chr1_+_264741911 0.01 ENSRNOT00000019956
semaphorin 4G
chr2_-_22059149 0.01 ENSRNOT00000031909
family with sequence similarity 151, member B
chr1_-_198900375 0.01 ENSRNOT00000024969
zinc finger protein 689
chr13_+_89586283 0.01 ENSRNOT00000079355
ENSRNOT00000049873
nuclear receptor subfamily 1, group I, member 3
chr10_+_61685241 0.01 ENSRNOT00000092606
MAX network transcriptional repressor
chr4_-_163890801 0.01 ENSRNOT00000081946
immunoreceptor Ly49si1
chr12_-_38916237 0.01 ENSRNOT00000074517
transmembrane protein 120B
chr10_+_67762995 0.01 ENSRNOT00000000253
zinc finger protein 207
chr5_-_88612626 0.01 ENSRNOT00000089560
transducin like enhancer of split 1
chr2_+_149214265 0.01 ENSRNOT00000084020
mediator complex subunit 12-like
chr7_-_11400805 0.01 ENSRNOT00000027634
death-associated protein kinase 3
chr13_+_99005142 0.01 ENSRNOT00000004293
acyl-CoA binding domain containing 3
chr1_+_219764001 0.01 ENSRNOT00000082388
pyruvate carboxylase
chr12_+_30198822 0.01 ENSRNOT00000041645
glucuronidase, beta
chr2_+_86914989 0.01 ENSRNOT00000085164
ENSRNOT00000081966
zinc finger protein 457-like
chr10_-_71849293 0.01 ENSRNOT00000003799
LIM homeobox 1
chr14_+_4125380 0.01 ENSRNOT00000002882
zinc finger protein 644
chr18_-_37245809 0.01 ENSRNOT00000079585
protein phosphatase 2, regulatory subunit B, beta
chr7_-_80457816 0.01 ENSRNOT00000039430

chr10_+_53621375 0.01 ENSRNOT00000004147
myosin heavy chain 3
chr5_+_64892802 0.01 ENSRNOT00000059869
ring finger protein 20
chr8_+_61671513 0.00 ENSRNOT00000091128
protein tyrosine phosphatase, non-receptor type 9
chr14_+_48726045 0.00 ENSRNOT00000086646
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_+_17115412 0.00 ENSRNOT00000015876
Rpgrip1-like
chr16_+_2278701 0.00 ENSRNOT00000016233
DENN domain containing 6A
chrX_+_115351114 0.00 ENSRNOT00000047553
high-mobility group (nonhistone chromosomal) protein 1-like 1
chr15_+_51303909 0.00 ENSRNOT00000085237
ENSRNOT00000058663
lysyl oxidase-like 2
chr1_+_84584596 0.00 ENSRNOT00000032933
zinc finger protein 60-like
chr4_-_108008484 0.00 ENSRNOT00000007971
catenin alpha 2
chr10_+_80790168 0.00 ENSRNOT00000073315
ENSRNOT00000075163
carbonic anhydrase 10
chr2_-_190100276 0.00 ENSRNOT00000015351
S100 calcium binding protein A9
chr3_-_177078594 0.00 ENSRNOT00000020695
uridine-cytidine kinase 1-like 1
chr2_-_111793326 0.00 ENSRNOT00000092660
neuroligin 1
chrX_-_74968405 0.00 ENSRNOT00000035653
similar to KIAA2022 protein
chr17_-_15429322 0.00 ENSRNOT00000093381
nucleolar protein 8
chr4_-_119568736 0.00 ENSRNOT00000041234
aprataxin and PNKP like factor
chr2_+_44512895 0.00 ENSRNOT00000013218
solute carrier family 38, member 9
chr17_-_14589154 0.00 ENSRNOT00000073035
nucleolar protein 8
chr2_-_198706428 0.00 ENSRNOT00000085006
RNA polymerase III subunit G like
chr1_+_193844538 0.00 ENSRNOT00000065311

chr17_-_15429051 0.00 ENSRNOT00000074667
nucleolar protein 8
chr10_-_89700283 0.00 ENSRNOT00000028213
ets variant 4
chr4_+_96831880 0.00 ENSRNOT00000068400
RSA-14-44 protein
chr10_-_12871965 0.00 ENSRNOT00000004583
predicted gene 8225
chr20_+_25990304 0.00 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr1_-_141504111 0.00 ENSRNOT00000040164
small nuclear ribonucleoprotein polypeptide E pseudogene 2
chr9_+_44681494 0.00 ENSRNOT00000035785
eukaryotic translation initiation factor 5B
chr1_+_256955652 0.00 ENSRNOT00000020411
leucine-rich, glioma inactivated 1
chr17_+_69365453 0.00 ENSRNOT00000023133
aldo-keto reductase family 1, member E2
chr15_-_27798408 0.00 ENSRNOT00000088981
telomerase associated protein 1
chr2_-_258932200 0.00 ENSRNOT00000045905
adhesion G protein-coupled receptor L2
chr3_+_129599353 0.00 ENSRNOT00000008734
synaptosomal-associated protein 25

Network of associatons between targets according to the STRING database.

First level regulatory network of Onecut2_Onecut3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.0 GO:0070662 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.0 GO:0046103 inosine biosynthetic process(GO:0046103)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.0 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)