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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Obox6_Obox5

Z-value: 0.92

Motif logo

Transcription factors associated with Obox6_Obox5

Gene Symbol Gene ID Gene Info

Activity profile of Obox6_Obox5 motif

Sorted Z-values of Obox6_Obox5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_71973419 0.57 ENSRNOT00000079895
coiled-coil and C2 domain containing 2A
chr7_-_93826665 0.53 ENSRNOT00000011344
TNF receptor superfamily member 11B
chr14_+_9226125 0.50 ENSRNOT00000088047
WD repeat and FYVE domain containing 3
chr1_-_97785490 0.48 ENSRNOT00000019364
LRRGT00021
chr7_-_116106368 0.42 ENSRNOT00000035678
lymphocyte antigen 6 complex, locus K
chr6_+_106084815 0.39 ENSRNOT00000058195
signal-induced proliferation-associated 1 like 1
chrX_-_70460536 0.38 ENSRNOT00000076824
PDZ domain containing 11
chr7_-_116063078 0.38 ENSRNOT00000076932
ENSRNOT00000035496
glycosylphosphatidylinositol anchored molecule like
chr1_+_87563975 0.36 ENSRNOT00000088772
zinc finger protein 30
chr3_+_124896618 0.36 ENSRNOT00000028888
CDP-diacylglycerol synthase 2
chr13_-_49828720 0.36 ENSRNOT00000012984
MDM4, p53 regulator
chr2_-_167607919 0.35 ENSRNOT00000089083

chr20_+_28572242 0.35 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr11_+_71151132 0.33 ENSRNOT00000082594
ENSRNOT00000082435
RUN and cysteine rich domain containing beclin 1 interacting protein
chr11_+_57207656 0.33 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr4_+_66090209 0.31 ENSRNOT00000031193
tetratricopeptide repeat domain 26
chr6_-_107325345 0.30 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
NUMB, endocytic adaptor protein
chr1_+_84685931 0.30 ENSRNOT00000063839
zinc finger protein 780B
chr19_+_27603307 0.30 ENSRNOT00000074702

chr1_-_4011161 0.29 ENSRNOT00000044778
syntaxin binding protein 5
chr17_+_35396286 0.29 ENSRNOT00000089613
ENSRNOT00000092638
exocyst complex component 2
chr13_+_50103189 0.29 ENSRNOT00000004078
ATPase plasma membrane Ca2+ transporting 4
chrM_+_11736 0.28 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr12_-_10335499 0.28 ENSRNOT00000071567
WAS protein family, member 3
chr6_+_135610743 0.27 ENSRNOT00000010906
Tnf receptor-associated factor 3
chr7_-_118474609 0.27 ENSRNOT00000089076

chr20_-_8574082 0.26 ENSRNOT00000048845
MAM domain containing glycosylphosphatidylinositol anchor 1
chr9_-_17209220 0.25 ENSRNOT00000083764
GTP binding protein 2
chr20_-_5927070 0.25 ENSRNOT00000059264
solute carrier family 26 member 8
chr18_-_74485139 0.25 ENSRNOT00000022598
solute carrier family 14 member 1
chr7_-_124929025 0.25 ENSRNOT00000015447
EF-hand calcium binding domain 6
chr5_+_6373583 0.25 ENSRNOT00000084749

chr6_+_144156175 0.25 ENSRNOT00000006582
extended synaptotagmin 2
chr4_+_152450126 0.24 ENSRNOT00000076930
RAD52 homolog, DNA repair protein
chr9_-_88816898 0.24 ENSRNOT00000083667
solute carrier family 19 member 3
chr13_+_34365147 0.23 ENSRNOT00000093066
cytoplasmic linker associated protein 1
chr14_+_39663421 0.23 ENSRNOT00000003197
gamma-aminobutyric acid type A receptor alpha2 subunit
chr1_-_4011511 0.23 ENSRNOT00000040559
syntaxin binding protein 5
chr2_+_66940057 0.22 ENSRNOT00000043050
cadherin 9
chr4_+_163112301 0.22 ENSRNOT00000087113
C-type lectin domain family 12, member A
chr1_+_99505677 0.22 ENSRNOT00000024645
zinc finger protein 719
chr7_-_120770435 0.22 ENSRNOT00000077000
DEAD-box helicase 17
chr8_-_69466618 0.22 ENSRNOT00000042925
iduronate 2-sulfatase
chr17_-_32783427 0.22 ENSRNOT00000059921
serine (or cysteine) peptidase inhibitor, clade B, member 6b
chr7_+_20262680 0.21 ENSRNOT00000046378
similar to hypothetical protein 4930509O22
chr5_+_5616483 0.21 ENSRNOT00000011026
nuclear receptor coactivator 2
chr3_+_48106099 0.20 ENSRNOT00000007218
solute carrier family 4 member 10
chr2_+_34186091 0.20 ENSRNOT00000016129
small glutamine rich tetratricopeptide repeat containing beta
chr8_-_22150005 0.20 ENSRNOT00000041678
tyrosine kinase 2
chr13_-_113817995 0.20 ENSRNOT00000057151
CD46 molecule
chr10_+_10875983 0.20 ENSRNOT00000052265
similar to 60S ribosomal protein L37a
chr12_-_19294888 0.19 ENSRNOT00000001815
zinc finger protein 3
chr19_-_56789404 0.19 ENSRNOT00000058652
similar to TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr1_+_192379543 0.19 ENSRNOT00000078705
protein kinase C, beta
chr4_-_51586881 0.19 ENSRNOT00000064983
IQ motif and ubiquitin domain containing
chr8_-_116532169 0.18 ENSRNOT00000085364
RNA binding motif protein 5
chr3_+_94530586 0.18 ENSRNOT00000067860
cleavage stimulation factor subunit 3
chr11_+_61531416 0.18 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr10_-_55997299 0.18 ENSRNOT00000074505
cytochrome b5 domain containing 1
chr3_-_121488540 0.18 ENSRNOT00000023845
zinc finger CCCH type containing 8
chr4_+_140092352 0.17 ENSRNOT00000008892
SET domain and mariner transposase fusion gene
chr2_+_127489771 0.17 ENSRNOT00000093581
inturned planar cell polarity protein
chr12_-_10391270 0.17 ENSRNOT00000092340
WAS protein family, member 3
chr6_-_54059119 0.17 ENSRNOT00000005521
histone deacetylase 9
chr17_+_19249952 0.17 ENSRNOT00000023140
ataxin 1
chr1_+_11963836 0.17 ENSRNOT00000074325

chr15_+_36809361 0.17 ENSRNOT00000076667
poly (ADP-ribose) polymerase family, member 4
chr10_+_56381813 0.17 ENSRNOT00000019687
zinc finger and BTB domain containing 4
chr11_+_30550141 0.16 ENSRNOT00000002866
hormonally upregulated Neu-associated kinase
chr6_-_115616766 0.16 ENSRNOT00000006143
ENSRNOT00000045870
SEL1L ERAD E3 ligase adaptor subunit
chrM_+_9870 0.16 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr3_-_162059524 0.16 ENSRNOT00000033873
zinc finger protein 334
chr1_+_65522118 0.16 ENSRNOT00000058563
myeloid zinc finger 1
chr3_+_154863072 0.16 ENSRNOT00000055200
small nucleolar RNA host gene 11
chr17_-_67904674 0.16 ENSRNOT00000078532
Kruppel-like factor 6
chr12_-_15996958 0.16 ENSRNOT00000039726
archaelysin family metallopeptidase 1
chr18_-_71701423 0.16 ENSRNOT00000024716
cap binding complex dependent translation initiation factor
chr2_-_2779109 0.15 ENSRNOT00000017098
Rieske (Fe-S) domain containing
chr2_+_206454208 0.15 ENSRNOT00000026863
putative homeodomain transcription factor 1
chr2_-_106703401 0.15 ENSRNOT00000043933

chr4_+_9981958 0.15 ENSRNOT00000015322
N-acyl phosphatidylethanolamine phospholipase D
chr17_+_16455026 0.15 ENSRNOT00000022932
zinc finger protein 169
chr14_+_108415068 0.15 ENSRNOT00000083763
pseudouridylate synthase 10
chr7_+_70946228 0.15 ENSRNOT00000039306
signal transducer and activator of transcription 6
chr13_-_70625842 0.15 ENSRNOT00000092499
laminin subunit gamma 2
chr14_+_8182383 0.15 ENSRNOT00000092719
mitogen activated protein kinase 10
chr10_+_35343189 0.14 ENSRNOT00000083688
mitogen-activated protein kinase 9
chr4_-_150616895 0.14 ENSRNOT00000073562
ankyrin repeat domain 26
chr1_+_15782477 0.14 ENSRNOT00000088025
ENSRNOT00000089966
BCL2-associated transcription factor 1
chr10_-_35175647 0.14 ENSRNOT00000078960
CCR4-NOT transcription complex, subunit 6
chr6_+_86862790 0.14 ENSRNOT00000093492
Fanconi anemia, complementation group M
chr8_+_21611319 0.14 ENSRNOT00000068461
zinc finger protein 846
chr6_+_122729874 0.14 ENSRNOT00000039509
ENSRNOT00000040440
zinc finger CCCH type containing 14
chr16_-_14360555 0.14 ENSRNOT00000065460
hypothetical gene supported by AF152002
chr4_+_87026530 0.14 ENSRNOT00000018425
AVL9 cell migration associated
chr3_+_63379031 0.13 ENSRNOT00000068199
oxysterol binding protein-like 6
chr18_+_30864216 0.13 ENSRNOT00000027015
protocadherin gamma subfamily A, 7
chr6_+_80159364 0.13 ENSRNOT00000005439
pinin, desmosome associated protein
chr1_+_141447022 0.13 ENSRNOT00000020690

chr9_+_12114977 0.13 ENSRNOT00000073673

chr4_+_181481147 0.13 ENSRNOT00000002523
kelch-like family, member 42
chr13_-_70980913 0.13 ENSRNOT00000003713
N-acetylneuraminate pyruvate lyase
chr2_+_144646308 0.13 ENSRNOT00000078337
ENSRNOT00000093407
doublecortin-like kinase 1
chr6_+_27328406 0.13 ENSRNOT00000091159
ENSRNOT00000044278
otoferlin
chr18_-_32207749 0.13 ENSRNOT00000090882
ENSRNOT00000018843
Rho GTPase activating protein 26
chr6_-_4520604 0.12 ENSRNOT00000042230
ENSRNOT00000043870
ENSRNOT00000070918
ENSRNOT00000046246
ENSRNOT00000052367
ENSRNOT00000042251
solute carrier family 8 member A1
chr7_+_27620458 0.12 ENSRNOT00000059532
similar to FLJ25323 protein
chr4_+_170518673 0.12 ENSRNOT00000011803
activating transcription factor 7 interacting protein
chr15_+_41448064 0.12 ENSRNOT00000019551
sacsin molecular chaperone
chr3_-_165700489 0.12 ENSRNOT00000017008
zinc finger protein 93
chr6_+_9790422 0.12 ENSRNOT00000020959
protein kinase C, epsilon
chr18_+_56414488 0.12 ENSRNOT00000088988
colony stimulating factor 1 receptor
chr1_+_234252757 0.12 ENSRNOT00000091814
RAR-related orphan receptor B
chr14_-_114649173 0.12 ENSRNOT00000083528
spectrin, beta, non-erythrocytic 1
chr13_+_77602249 0.12 ENSRNOT00000003407
ENSRNOT00000076589
tenascin R
chr8_-_96516975 0.12 ENSRNOT00000067996
similar to RIKEN cDNA 4930579C12 gene
chr4_-_26255639 0.12 ENSRNOT00000031118

chrX_+_128416722 0.12 ENSRNOT00000009336
ENSRNOT00000085110
X-linked inhibitor of apoptosis
chr8_-_84506328 0.12 ENSRNOT00000064754
muscular LMNA-interacting protein
chr14_-_46153212 0.12 ENSRNOT00000079269
NACHT and WD repeat domain containing 2
chr2_+_248178389 0.12 ENSRNOT00000037339
guanylate binding protein 5
chr3_-_80012750 0.12 ENSRNOT00000018154
nuclear receptor subfamily 1, group H, member 3
chr12_-_41448668 0.11 ENSRNOT00000001856
RAS protein activator like 1 (GAP1 like)
chr10_+_5930298 0.11 ENSRNOT00000044626
glutamate ionotropic receptor NMDA type subunit 2A
chr6_-_91581262 0.11 ENSRNOT00000034507

chr13_+_6679368 0.11 ENSRNOT00000067198
ENSRNOT00000092965
contactin associated protein-like 5C
chr3_+_97723901 0.11 ENSRNOT00000080416
metallophosphoesterase domain containing 2
chr1_-_84732242 0.11 ENSRNOT00000025586
zinc finger protein 59-like
chr9_+_73687743 0.11 ENSRNOT00000079495
ENSRNOT00000017197
ribulose-5-phosphate-3-epimerase
chr17_+_87274944 0.11 ENSRNOT00000073718
enhancer trap locus 4
chr4_-_153593773 0.11 ENSRNOT00000082982
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr13_-_100450209 0.11 ENSRNOT00000090712
lamin B receptor
chr8_+_93439648 0.11 ENSRNOT00000043008
ribosomal protein S20-like
chr4_-_85329362 0.11 ENSRNOT00000014925
corticotropin releasing hormone receptor 2
chr3_+_98297554 0.11 ENSRNOT00000006524
potassium voltage-gated channel subfamily A member 4
chr10_-_67751002 0.11 ENSRNOT00000000254
similar to Protein Njmu-R1
chr4_-_148446303 0.11 ENSRNOT00000017633
arachidonate 5-lipoxygenase
chr10_-_62698541 0.11 ENSRNOT00000019759
coronin 6
chr3_+_56030915 0.11 ENSRNOT00000010489
phosphatase, orphan 2
chr7_-_129919946 0.11 ENSRNOT00000079976

chr1_+_78893271 0.11 ENSRNOT00000029825
paraneoplastic Ma antigen family-like 1
chr12_-_30770791 0.11 ENSRNOT00000093734
splicing factor SWAP homolog
chr13_-_73056765 0.11 ENSRNOT00000000049
xenotropic and polytropic retrovirus receptor 1
chr17_+_54298409 0.11 ENSRNOT00000084919
Rho GTPase activating protein 12
chr5_-_161879133 0.11 ENSRNOT00000041175
PR/SET domain 2
chr2_+_54191538 0.11 ENSRNOT00000019524
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_+_124680294 0.10 ENSRNOT00000014720
metallophosphoesterase domain containing 1
chr1_-_211196868 0.10 ENSRNOT00000022714
mitogen-activated protein kinase 1 interacting protein 1
chr2_-_178521038 0.10 ENSRNOT00000033107
relaxin/insulin-like family peptide receptor 1
chr7_+_13151592 0.10 ENSRNOT00000010203
vomeronasal 2 receptor, 53
chr16_+_84465656 0.10 ENSRNOT00000043188
LRRGT00175
chr19_-_22194740 0.10 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr11_-_38457373 0.10 ENSRNOT00000041177
zinc finger protein 295
chr20_+_20236151 0.10 ENSRNOT00000079630
ankyrin 3
chr14_+_109533792 0.10 ENSRNOT00000067690
ankyrin repeat domain-containing protein 29-like
chr9_-_30844199 0.10 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr18_-_86878142 0.10 ENSRNOT00000058139
docking protein 6
chr5_-_59085676 0.10 ENSRNOT00000068105
microseminoprotein, prostate associated
chr11_-_77593171 0.10 ENSRNOT00000002645
ENSRNOT00000043498
interleukin 1 receptor accessory protein
chr12_-_38638536 0.10 ENSRNOT00000001690
MLX interacting protein
chr6_-_50923510 0.10 ENSRNOT00000010631
B-cell receptor-associated protein 29
chr6_+_78567970 0.10 ENSRNOT00000032743
tetratricopeptide repeat domain 6
chr2_+_86891092 0.10 ENSRNOT00000077162
ENSRNOT00000083066
zinc finger protein 457-like
chr16_+_46731403 0.10 ENSRNOT00000017624
teneurin transmembrane protein 3
chr16_-_21362955 0.10 ENSRNOT00000039607
Gem-interacting protein
chr17_+_69654170 0.10 ENSRNOT00000058351
aldo-keto reductase family 1, member C19
chr11_+_66316606 0.10 ENSRNOT00000041715
syntaxin binding protein 5-like
chr6_-_38228379 0.10 ENSRNOT00000084924
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr4_-_15859132 0.10 ENSRNOT00000082161
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr4_-_155763500 0.10 ENSRNOT00000071745
solute carrier family 2, facilitated glucose transporter member 3-like
chr4_+_179398621 0.10 ENSRNOT00000049474
ENSRNOT00000067506
lymphoid-restricted membrane protein
chr1_+_224998172 0.10 ENSRNOT00000026321
zinc finger and BTB domain containing 3
chr14_+_83298674 0.09 ENSRNOT00000024813
phosphatidylserine decarboxylase
chr2_+_58448917 0.09 ENSRNOT00000082562
RAN binding protein 3-like
chr18_+_30831365 0.09 ENSRNOT00000067185
protocadherin gamma subfamily A, 4
chr3_-_79282493 0.09 ENSRNOT00000049832
protein tyrosine phosphatase, receptor type, J
chr1_+_104106245 0.09 ENSRNOT00000019175
ENSRNOT00000081660
zinc finger, DHHC-type containing 13
chr10_+_11786121 0.09 ENSRNOT00000033919
SLX4 structure-specific endonuclease subunit
chr11_+_60102121 0.09 ENSRNOT00000045521
transmembrane protease, serine 7
chr3_-_12155098 0.09 ENSRNOT00000082696
GTPase activating Rap/RanGAP domain-like 3
chr13_-_89545182 0.09 ENSRNOT00000078402
Purkinje cell protein 4-like 1
chr1_+_72874404 0.09 ENSRNOT00000058900
dynein, axonemal, assembly factor 3
chr9_-_81864202 0.09 ENSRNOT00000084964
zinc finger protein 142
chr14_+_81858737 0.09 ENSRNOT00000029784
ENSRNOT00000058068
ENSRNOT00000058067
DNA polymerase nu
chr10_-_2037891 0.09 ENSRNOT00000004563
ERCC excision repair 4, endonuclease catalytic subunit
chr4_-_117589464 0.09 ENSRNOT00000021167
N-acetyltransferase 8 (GCN5-related) family member 1
chr1_-_4011353 0.09 ENSRNOT00000049699
syntaxin binding protein 5
chr1_-_248376750 0.09 ENSRNOT00000089073
glycine decarboxylase
chr18_+_30487264 0.09 ENSRNOT00000040125
protocadherin beta 10
chr6_-_1454480 0.09 ENSRNOT00000072810
eukaryotic translation initiation factor 2-alpha kinase 2
chr18_-_76653056 0.09 ENSRNOT00000078496
ADNP homeobox 2
chr3_+_80833272 0.09 ENSRNOT00000023583
cholinergic receptor, muscarinic 4
chr3_+_11392791 0.09 ENSRNOT00000064792
CDKN1A interacting zinc finger protein 1
chr8_+_131965134 0.09 ENSRNOT00000078308
zinc finger protein 660
chr4_+_147455533 0.09 ENSRNOT00000081957
tRNA splicing endonuclease subunit 2
chr8_-_94920441 0.09 ENSRNOT00000014165
centrosomal protein 162
chr14_+_113867209 0.09 ENSRNOT00000067591
coiled coil domain containing 88A
chr19_-_15540773 0.09 ENSRNOT00000022359
lysophosphatidylcholine acyltransferase 2
chr4_+_85427555 0.09 ENSRNOT00000015469
family with sequence similarity 188, member B
chr3_-_21669957 0.09 ENSRNOT00000012354
ENSRNOT00000078718
ring finger and CCCH-type domains 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Obox6_Obox5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.1 0.6 GO:0035973 aggrephagy(GO:0035973)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.4 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 0.2 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.0 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.1 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.4 GO:0003181 atrioventricular valve morphogenesis(GO:0003181)
0.0 0.1 GO:0042938 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.1 GO:0046548 amacrine cell differentiation(GO:0035881) retinal rod cell development(GO:0046548)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0042496 detection of diacyl bacterial lipopeptide(GO:0042496) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:0061193 taste bud development(GO:0061193)
0.0 0.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:1990910 response to hypobaric hypoxia(GO:1990910)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.1 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.3 GO:0015265 urea channel activity(GO:0015265)
0.1 0.2 GO:0015563 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors