ISMARA results: Nr4a2

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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nr4a2

Z-value: 0.37

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Transcription factors associated with Nr4a2

Gene Symbol	Gene ID	Gene Info
Nr4a2 NCBI RGD Ensembl	ENSRNOG00000005600	nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nr4a2	rn6_v1_chr3_-_43117337_43117337	0.50	3.9e-01	Click!

Activity profile of Nr4a2 motif

Sorted Z-values of Nr4a2 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_61531416 Show fit	0.15	ENSRNOT00000093263	Atp6v1a NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit A
chr8_+_114867062 Show fit	0.14	ENSRNOT00000074771	Wdr82 NCBI RGD Ensembl Show fit	WD repeat domain 82
chr3_+_62648447 Show fit	0.11	ENSRNOT00000002111	Agps NCBI RGD Ensembl Show fit	alkylglycerone phosphate synthase
chr4_-_89281222 Show fit	0.10	ENSRNOT00000010898	Fam13a NCBI RGD Ensembl Show fit	family with sequence similarity 13, member A
chr8_+_71591360 Show fit	0.09	ENSRNOT00000090096	Csnk1g1 NCBI RGD Ensembl Show fit	casein kinase 1, gamma 1
chr1_+_219000844 Show fit	0.09	ENSRNOT00000022486	Kmt5b NCBI RGD Ensembl Show fit	lysine methyltransferase 5B
chr3_+_131351587 Show fit	0.09	ENSRNOT00000010835	Btbd3 NCBI RGD Ensembl Show fit	BTB domain containing 3
chr3_+_80676820 Show fit	0.08	ENSRNOT00000084809	Ambra1 NCBI RGD Ensembl Show fit	autophagy and beclin 1 regulator 1
chr3_-_60795951 Show fit	0.07	ENSRNOT00000002174	Atf2 NCBI RGD Ensembl Show fit	activating transcription factor 2
chr7_+_35069814 Show fit	0.07	ENSRNOT00000089228	Nr2c1 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 2, group C, member 1

Showing 1 to 10 of 70 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.1	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	GO:0048880	medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
0.0	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)

Showing 1 to 8 of 8 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)

Showing 1 to 4 of 4 entries

Results for Nr4a2

Z-value: 0.37

Motif logo

Transcription factors associated with Nr4a2

Activity-expression correlation:

Activity profile of Nr4a2 motif

Sorted Z-values of Nr4a2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: