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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nr4a2

Z-value: 0.37

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Transcription factors associated with Nr4a2

Gene Symbol Gene ID Gene Info
ENSRNOG00000005600 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a2rn6_v1_chr3_-_43117337_431173370.503.9e-01Click!

Activity profile of Nr4a2 motif

Sorted Z-values of Nr4a2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_61531416 0.15 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr8_+_114867062 0.14 ENSRNOT00000074771
WD repeat domain 82
chr3_+_62648447 0.11 ENSRNOT00000002111
alkylglycerone phosphate synthase
chr4_-_89281222 0.10 ENSRNOT00000010898
family with sequence similarity 13, member A
chr8_+_71591360 0.09 ENSRNOT00000090096
casein kinase 1, gamma 1
chr1_+_219000844 0.09 ENSRNOT00000022486
lysine methyltransferase 5B
chr3_+_131351587 0.09 ENSRNOT00000010835
BTB domain containing 3
chr3_+_80676820 0.08 ENSRNOT00000084809
autophagy and beclin 1 regulator 1
chr3_-_60795951 0.07 ENSRNOT00000002174
activating transcription factor 2
chr7_+_35069814 0.07 ENSRNOT00000089228
nuclear receptor subfamily 2, group C, member 1
chr10_-_36372436 0.07 ENSRNOT00000039827
zinc finger protein 454
chr18_+_29490981 0.07 ENSRNOT00000032316
eukaryotic translation initiation factor 4E binding protein 3
chr3_-_72113680 0.07 ENSRNOT00000009708
zinc finger, DHHC-type containing 5
chrX_+_22302485 0.07 ENSRNOT00000082902
lysine demethylase 5C
chr6_-_27512287 0.06 ENSRNOT00000085937
ENSRNOT00000081278
ENSRNOT00000081323
selenoprotein I
chr7_-_40316532 0.06 ENSRNOT00000083347
similar to RIKEN cDNA C430008C19
chr12_-_24537313 0.06 ENSRNOT00000001975
bromodomain adjacent to zinc finger domain, 1B
chrX_+_22302703 0.06 ENSRNOT00000078617
ENSRNOT00000086952
lysine demethylase 5C
chr1_-_71173216 0.06 ENSRNOT00000020523
zinc finger protein 28
chr6_+_26537707 0.06 ENSRNOT00000050102
zinc finger protein 513
chr3_+_121596791 0.06 ENSRNOT00000024694
tubulin tyrosine ligase
chr7_-_81592206 0.06 ENSRNOT00000007979
angiopoietin 1
chr3_+_155297566 0.06 ENSRNOT00000021435
ENSRNOT00000084866
DEAH-box helicase 35
chr15_+_3996048 0.06 ENSRNOT00000078653
N-deacetylase and N-sulfotransferase 2
chr18_+_45023932 0.05 ENSRNOT00000039379
family with sequence similarity 170, member A
chr2_-_178389608 0.05 ENSRNOT00000013262
electron transfer flavoprotein dehydrogenase
chr12_-_5822874 0.05 ENSRNOT00000075920
FRY microtubule binding protein
chr14_+_42714315 0.05 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr18_-_26211445 0.05 ENSRNOT00000027739
neuronal regeneration related protein
chr7_+_53630621 0.05 ENSRNOT00000067011
ENSRNOT00000080598
cysteine and glycine-rich protein 2
chr3_+_47453821 0.05 ENSRNOT00000081682
TRAF family member-associated NFKB activator
chr10_-_18443934 0.05 ENSRNOT00000059895
ENSRNOT00000080021
RAN binding protein 17
chr1_-_213973163 0.04 ENSRNOT00000024867
cell cycle exit and neuronal differentiation protein 1-like
chr7_+_35070284 0.04 ENSRNOT00000009578
nuclear receptor subfamily 2, group C, member 1
chr18_+_79813759 0.03 ENSRNOT00000021768
zinc finger protein 516
chr1_-_81144024 0.03 ENSRNOT00000088431
zinc finger protein 94
chr3_-_2123820 0.03 ENSRNOT00000086843
euchromatic histone lysine methyltransferase 1
chr7_+_117001084 0.03 ENSRNOT00000066233
zinc finger protein 707-like 1
chr10_-_82399484 0.03 ENSRNOT00000082972
ENSRNOT00000055582
xylosyltransferase 2
chr1_+_255185629 0.03 ENSRNOT00000083002
HECT domain E3 ubiquitin protein ligase 2
chr20_+_3827086 0.03 ENSRNOT00000081588
retinoid X receptor beta
chr11_-_69201380 0.03 ENSRNOT00000085618
myosin light chain kinase
chr13_+_100817359 0.02 ENSRNOT00000004330
tumor protein p53 binding protein, 2
chr11_+_61531571 0.02 ENSRNOT00000093467
ENSRNOT00000002727
ATPase H+ transporting V1 subunit A
chr7_+_12840938 0.02 ENSRNOT00000039232
RNA polymerase mitochondrial
chr9_-_69953182 0.02 ENSRNOT00000015852
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr3_+_113257688 0.02 ENSRNOT00000019320
microtubule-associated protein 1A
chr19_+_49637016 0.02 ENSRNOT00000016880
beta-carotene oxygenase 1
chr7_-_117288018 0.02 ENSRNOT00000091285
plectin
chr9_+_117795132 0.02 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chrX_-_135342996 0.02 ENSRNOT00000084848
ENSRNOT00000008503
apoptosis inducing factor, mitochondria associated 1
chr15_+_11298478 0.02 ENSRNOT00000007672
leucine rich repeat containing 3B
chr10_-_49009156 0.02 ENSRNOT00000072970
mitogen-activated protein kinase 7
chr2_+_153830586 0.02 ENSRNOT00000042576
membrane metallo-endopeptidase
chr20_+_3827367 0.02 ENSRNOT00000079967
retinoid X receptor beta
chr18_+_59096643 0.02 ENSRNOT00000025325
WD repeat domain 7
chr2_-_184289126 0.02 ENSRNOT00000081678
F-box and WD repeat domain containing 7
chr4_-_56438142 0.01 ENSRNOT00000077079
RNA binding motif protein 28
chr13_-_70174565 0.01 ENSRNOT00000067135
ral guanine nucleotide dissociation stimulator,-like 1
chr3_-_159775643 0.01 ENSRNOT00000010939
junctophilin 2
chr4_-_56438465 0.01 ENSRNOT00000064007
RNA binding motif protein 28
chr4_+_145653602 0.01 ENSRNOT00000038964
TatD DNase domain containing 2
chr9_+_94702129 0.01 ENSRNOT00000080930
neuraminidase 2
chr10_+_36590325 0.01 ENSRNOT00000085203
zinc finger protein 354A
chr1_+_167373678 0.01 ENSRNOT00000027685
ENSRNOT00000088370
stromal interaction molecule 1
chr2_+_196304492 0.01 ENSRNOT00000028640
LysM domain containing 1
chr9_+_2202511 0.00 ENSRNOT00000017556
SATB homeobox 1
chr14_+_83889089 0.00 ENSRNOT00000078980
MORC family CW-type zinc finger 2
chr19_+_51317425 0.00 ENSRNOT00000019298
cadherin 13
chr16_-_22561496 0.00 ENSRNOT00000016543
lipoprotein lipase

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0048880 medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)