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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nr3c2

Z-value: 1.11

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
Nr3c2
ENSRNOG00000034007 nuclear receptor subfamily 3, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr3c2rn6_v1_chr19_-_34752695_347526950.583.0e-01Click!

Activity profile of Nr3c2 motif

Sorted Z-values of Nr3c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_42271443 0.71 ENSRNOT00000085508
AABR07018132.1

chr19_+_27603307 0.69 ENSRNOT00000074702
AABR07043347.1

chr2_+_89254154 0.68 ENSRNOT00000073391
AABR07009221.1

chr3_-_76012929 0.64 ENSRNOT00000085199
AC111632.2

chr14_-_43855745 0.64 ENSRNOT00000083155
AC112624.1

chr3_+_116072294 0.63 ENSRNOT00000071786
AABR07053613.1

chr19_+_24655626 0.63 ENSRNOT00000086690
AC102976.1

chr3_+_95614562 0.63 ENSRNOT00000079990
AABR07053179.1

chr6_+_54438436 0.63 ENSRNOT00000091972
AABR07063893.1

chr2_-_167607919 0.62 ENSRNOT00000089083
AABR07011733.1

chr5_-_79899054 0.61 ENSRNOT00000074379
AC229945.1

chrX_+_153677811 0.61 ENSRNOT00000072808
AABR07042361.1

chr2_+_52152536 0.61 ENSRNOT00000072691
AABR07008293.2

chr11_-_17286846 0.60 ENSRNOT00000080073
AABR07033318.1

chr7_+_96195209 0.60 ENSRNOT00000073584
AABR07057961.1

chr16_+_33373423 0.58 ENSRNOT00000091672
AABR07025316.1

chr19_-_21970103 0.57 ENSRNOT00000074210
AABR07043115.1

chr13_+_29839867 0.57 ENSRNOT00000090623
AABR07020537.1

chr10_-_52483325 0.57 ENSRNOT00000083485
AABR07029809.1

chr6_-_86161333 0.57 ENSRNOT00000072471
AABR07064590.1

chr16_+_33373615 0.56 ENSRNOT00000079157
AABR07025316.1

chr2_+_166475070 0.55 ENSRNOT00000071111
AABR07011700.1

chr2_+_70490155 0.49 ENSRNOT00000078674
AABR07008681.1

chrX_+_82710329 0.49 ENSRNOT00000074962
AABR07039694.1

chr18_-_15284077 0.38 ENSRNOT00000046326
LOC498826
LRRGT00165
chr7_+_143707237 0.36 ENSRNOT00000074212
Tns2
tensin 2
chr1_+_27476375 0.35 ENSRNOT00000047224
ENSRNOT00000075427
LOC102551716
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr9_+_73319710 0.33 ENSRNOT00000092485
Map2
microtubule-associated protein 2
chr12_-_38869346 0.26 ENSRNOT00000001807
Setd1b
SET domain containing 1B
chrX_+_62366453 0.26 ENSRNOT00000089828
Arx
aristaless related homeobox
chr4_-_159079003 0.17 ENSRNOT00000026691
Kcna5
potassium voltage-gated channel subfamily A member 5
chr14_-_78377825 0.16 ENSRNOT00000068104
AABR07015812.1

chr4_-_32392007 0.16 ENSRNOT00000014946
Dlx5
distal-less homeobox 5
chr8_-_55144087 0.15 ENSRNOT00000039045
Dixdc1
DIX domain containing 1
chr1_+_191344979 0.14 ENSRNOT00000023773
Hs3st2
heparan sulfate-glucosamine 3-sulfotransferase 2
chr6_-_26624092 0.12 ENSRNOT00000008113
Trim54
tripartite motif-containing 54
chr7_-_138483612 0.11 ENSRNOT00000085620
Slc38a4
solute carrier family 38, member 4
chr8_+_132441285 0.11 ENSRNOT00000087488
ENSRNOT00000068233
Lars2
leucyl-tRNA synthetase 2
chr6_-_11686682 0.09 ENSRNOT00000021998
Fbxo11
F-box protein 11
chr13_+_104816371 0.08 ENSRNOT00000086497
AABR07022057.1

chr11_-_57993548 0.08 ENSRNOT00000002957
Nectin3
nectin cell adhesion molecule 3
chr4_-_145555748 0.05 ENSRNOT00000013503
Fancd2os
FANCD2 opposite strand
chr1_+_91716383 0.05 ENSRNOT00000016919
Slc7a9
solute carrier family 7 member 9
chr14_+_45024351 0.03 ENSRNOT00000076753
Tlr6
toll-like receptor 6
chr7_+_2635743 0.02 ENSRNOT00000004223
Mip
major intrinsic protein of lens fiber
chr5_-_147303346 0.02 ENSRNOT00000009153
Hpca
hippocalcin
chr20_-_7943575 0.01 ENSRNOT00000066897
Tulp1
tubby like protein 1
chr7_-_26144466 0.00 ENSRNOT00000009162
Fhl4
four and a half LIM domains 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr3c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0042496 detection of diacyl bacterial lipopeptide(GO:0042496) detection of bacterial lipopeptide(GO:0070340)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.0 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663) diacyl lipopeptide binding(GO:0042498)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)