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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nr2f6

Z-value: 0.35

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Transcription factors associated with Nr2f6

Gene Symbol Gene ID Gene Info
ENSRNOG00000016892 nuclear receptor subfamily 2, group F, member 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2f6rn6_v1_chr16_-_19777414_19777414-0.444.6e-01Click!

Activity profile of Nr2f6 motif

Sorted Z-values of Nr2f6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_43001948 0.15 ENSRNOT00000007374
hippocalcin-like 1
chr6_+_123361864 0.14 ENSRNOT00000057577

chr20_+_13827660 0.13 ENSRNOT00000093131
D-dopachrome tautomerase
chr10_+_11146359 0.13 ENSRNOT00000006314
presequence translocase associated motor 16 homolog
chr5_-_156734541 0.11 ENSRNOT00000021036
cytidine deaminase-like
chr18_-_410098 0.10 ENSRNOT00000084138
cx9C motif-containing protein 4-like
chr1_-_219144610 0.09 ENSRNOT00000023526
NADH:ubiquinone oxidoreductase core subunit S8
chr4_+_150199627 0.08 ENSRNOT00000052259

chr10_+_3227160 0.08 ENSRNOT00000088075
N-terminal asparagine amidase
chr3_-_2938883 0.08 ENSRNOT00000084196
allergen Fel d 4-like
chr6_+_26051396 0.08 ENSRNOT00000006452
ribokinase
chr1_-_89488223 0.07 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr1_-_64175099 0.07 ENSRNOT00000091288
NADH:ubiquinone oxidoreductase subunit A3
chr7_+_117951154 0.07 ENSRNOT00000060181
zinc finger protein 7
chr15_-_45376476 0.07 ENSRNOT00000065838
deleted in lymphocytic leukemia, 7
chr13_-_44345735 0.07 ENSRNOT00000005006
transmembrane protein 163
chr5_+_137257287 0.07 ENSRNOT00000037160
ELOVL fatty acid elongase 1
chr3_+_2462466 0.06 ENSRNOT00000014087
ring finger protein 208
chr9_+_69953440 0.06 ENSRNOT00000034740
eukaryotic translation elongation factor 1 beta 2
chr20_-_3819200 0.06 ENSRNOT00000000542
ENSRNOT00000081486
hydroxysteroid (17-beta) dehydrogenase 8
chr20_+_13827132 0.06 ENSRNOT00000001664
D-dopachrome tautomerase
chr16_+_74810938 0.06 ENSRNOT00000058091
NIMA-related kinase 5
chr2_+_95045034 0.06 ENSRNOT00000081305
mitochondrial ribosomal protein S28
chr12_-_18526250 0.06 ENSRNOT00000001791
acetylserotonin O-methyltransferase
chr15_+_38069320 0.06 ENSRNOT00000014397
Sin3-associated polypeptide 18
chr5_+_129257429 0.06 ENSRNOT00000072396
tetratricopeptide repeat domain 39A
chr2_-_196304169 0.05 ENSRNOT00000028639
sodium channel modifier 1
chr20_-_5123073 0.05 ENSRNOT00000001126
apolipoprotein M
chr1_-_281101438 0.05 ENSRNOT00000012734
RAB11 family interacting protein 2
chr11_-_61530567 0.05 ENSRNOT00000076277
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_239415046 0.05 ENSRNOT00000072196
CXXC finger protein 4
chr10_+_89352835 0.05 ENSRNOT00000028060
ribosomal protein L27
chr17_+_42302540 0.05 ENSRNOT00000025389
geminin, DNA replication inhibitor
chr17_+_85356042 0.05 ENSRNOT00000022201
COMM domain containing 3
chr9_-_27511176 0.05 ENSRNOT00000036813
similar to Glutathione S-transferase A1 (GTH1) (HA subunit 1) (GST-epsilon) (GSTA1-1) (GST class-alpha)
chr14_+_46001849 0.05 ENSRNOT00000076611
RELT-like 1
chr15_-_45947030 0.05 ENSRNOT00000035888
integrator complex subunit 6
chr1_+_189665976 0.05 ENSRNOT00000033673
LYR motif containing 1
chr13_-_90589466 0.05 ENSRNOT00000070812
phosphoprotein enriched in astrocytes 15
chr3_+_151691515 0.05 ENSRNOT00000052236

chr17_+_5281727 0.05 ENSRNOT00000024781
iron-sulfur cluster assembly 1
chr1_-_144601327 0.05 ENSRNOT00000029244
ENSRNOT00000078144
stabilizer of axonemal microtubules 2
chr3_-_3691972 0.05 ENSRNOT00000061735
quiescin sulfhydryl oxidase 2
chr3_-_161322289 0.05 ENSRNOT00000022594
phospholipid transfer protein
chr7_-_117688187 0.04 ENSRNOT00000019707
VPS28, ESCRT-I subunit
chr1_-_100231460 0.04 ENSRNOT00000032200
acid phosphatase, testicular
chr1_-_226049929 0.04 ENSRNOT00000007320
bestrophin 1
chr1_-_262013619 0.04 ENSRNOT00000021278
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr2_-_187706300 0.04 ENSRNOT00000092349
ENSRNOT00000026414
transmembrane protein 79
chr6_+_76174452 0.04 ENSRNOT00000084062
proteasome subunit alpha 6
chr5_+_137257637 0.04 ENSRNOT00000093001
ELOVL fatty acid elongase 1
chr9_+_64095978 0.04 ENSRNOT00000021533
matrix AAA peptidase interacting protein 1
chr13_-_89745835 0.04 ENSRNOT00000005352
kelch domain containing 9
chr14_-_79464770 0.04 ENSRNOT00000008932
GrpE-like 1, mitochondrial
chr18_-_29504975 0.04 ENSRNOT00000063841
ENSRNOT00000024313
amyloid beta precursor protein binding family B member 3
chr3_-_111037166 0.04 ENSRNOT00000017070
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr7_-_136853957 0.04 ENSRNOT00000008985
neural EGFL like 2
chr18_+_45023932 0.04 ENSRNOT00000039379
family with sequence similarity 170, member A
chr10_+_34975708 0.04 ENSRNOT00000064984
NHP2 ribonucleoprotein
chr14_-_86047162 0.03 ENSRNOT00000018227
phosphoglycerate mutase 2
chr1_+_100224401 0.03 ENSRNOT00000025846
Friend virus susceptibility 1
chr20_+_9643612 0.03 ENSRNOT00000050744
uromodulin-like 1
chr10_+_89635675 0.03 ENSRNOT00000028179
similar to SAP18
chr9_-_64096265 0.03 ENSRNOT00000013502
tRNA-yW synthesizing protein 5
chr3_+_8832740 0.03 ENSRNOT00000022552
phytanoyl-CoA dioxygenase domain containing 1
chr11_+_86890585 0.03 ENSRNOT00000002579
RAN binding protein 1
chr6_-_26051229 0.03 ENSRNOT00000005855
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr15_-_43733182 0.03 ENSRNOT00000015318
protein phosphatase 2, regulatory subunit B, alpha
chr3_-_111037425 0.03 ENSRNOT00000085628
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr3_+_112228720 0.03 ENSRNOT00000079079
calpain 3
chr1_+_47942800 0.03 ENSRNOT00000079312
Wilms tumor 1 associated protein
chr18_-_52017734 0.03 ENSRNOT00000081020
membrane associated ring-CH-type finger 3
chr20_+_4530342 0.03 ENSRNOT00000076352
ENSRNOT00000000478
ENSRNOT00000075925
negative elongation factor complex member E
chr11_-_70211701 0.03 ENSRNOT00000076114
mucin 13, cell surface associated
chr10_-_88143965 0.03 ENSRNOT00000080167
type I keratin KA11
chr4_+_157230769 0.03 ENSRNOT00000091464
ENSRNOT00000017472
prohibitin 2
chr3_+_154507035 0.03 ENSRNOT00000017265
regulation of nuclear pre-mRNA domain containing 1B
chr1_+_199248470 0.03 ENSRNOT00000025933
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_-_154170409 0.03 ENSRNOT00000089014
Hikeshi, heat shock protein nuclear import factor
chrX_+_157759624 0.03 ENSRNOT00000003192
similar to motile sperm domain containing 1
chr4_-_114853868 0.03 ENSRNOT00000090828
WD repeat domain 54
chr1_+_97712177 0.03 ENSRNOT00000027745
similar to RIKEN cDNA 4930433I11 gene
chr3_+_61658245 0.03 ENSRNOT00000033511
homeo box D3
chr2_-_188745144 0.03 ENSRNOT00000055533
CDC28 protein kinase regulatory subunit 1B
chr14_+_84465515 0.02 ENSRNOT00000035591
oncostatin M
chr13_-_80703615 0.02 ENSRNOT00000004599
flavin containing monooxygenase 4
chr11_+_74014983 0.02 ENSRNOT00000040884
glycoprotein V platelet
chr15_-_14510828 0.02 ENSRNOT00000039347
sentan, cilia apical structure protein
chr8_-_49075892 0.02 ENSRNOT00000082687
archain 1
chr1_-_222178725 0.02 ENSRNOT00000028697
estrogen related receptor, alpha
chr4_+_162437089 0.02 ENSRNOT00000038801
C-type lectin domain family 2 member D2
chr2_+_211050360 0.02 ENSRNOT00000026928
proteasome subunit alpha 5
chr10_-_85289777 0.02 ENSRNOT00000055427
ENSRNOT00000014863
G protein-coupled receptor 179
chr20_-_3751994 0.02 ENSRNOT00000072288
POU class 5 homeobox 1
chr8_+_55603968 0.02 ENSRNOT00000066848
POU class 2 associating factor 1
chr13_-_85622314 0.02 ENSRNOT00000005719
microsomal glutathione S-transferase 3
chr10_+_86399827 0.02 ENSRNOT00000009299
growth factor receptor bound protein 7
chr10_-_90312386 0.02 ENSRNOT00000028445
solute carrier family 4 member 1
chr20_-_3374344 0.02 ENSRNOT00000082999
protein phosphatase 1, regulatory subunit 18
chr20_-_5533448 0.02 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr4_-_113988246 0.02 ENSRNOT00000013128
WD repeat-containing protein 54
chr8_+_117455262 0.02 ENSRNOT00000027520
solute carrier family 25 member 20
chr2_+_189582991 0.02 ENSRNOT00000022627
RAB13, member RAS oncogene family
chr3_-_161272460 0.02 ENSRNOT00000020740
acyl-CoA thioesterase 8
chr20_-_12938891 0.02 ENSRNOT00000017141
similar to Protein C21orf58
chr1_+_47942500 0.02 ENSRNOT00000025936
Wilms tumor 1 associated protein
chr11_-_27971359 0.02 ENSRNOT00000085629
ENSRNOT00000051060
ENSRNOT00000042581
ENSRNOT00000050073
ENSRNOT00000081066
glutamate ionotropic receptor kainate type subunit 1
chr3_+_176217128 0.02 ENSRNOT00000013609
GID complex subunit 8
chr1_-_89543967 0.02 ENSRNOT00000079631
hepsin
chr15_-_80713153 0.02 ENSRNOT00000063800
kelch-like family member 1
chr1_+_100470722 0.02 ENSRNOT00000086917
aspartate dehydrogenase domain containing
chr2_+_44096061 0.02 ENSRNOT00000018438
ankyrin repeat domain 55
chr5_-_24320786 0.02 ENSRNOT00000061569
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr20_-_5533600 0.02 ENSRNOT00000072319
cutA divalent cation tolerance homolog
chr14_+_77079402 0.02 ENSRNOT00000042200
solute carrier family 2 member 9
chr1_-_98486976 0.01 ENSRNOT00000024083
electron transfer flavoprotein beta subunit
chr3_+_80021440 0.01 ENSRNOT00000018620
acid phosphatase 2, lysosomal
chr7_-_127081704 0.01 ENSRNOT00000055893
uncharacterized LOC108351584
chr7_+_12798868 0.01 ENSRNOT00000038553
protease, serine, 57
chr1_-_8878136 0.01 ENSRNOT00000064836
ENSRNOT00000075850
vesicle trafficking 1
chr19_-_20508711 0.01 ENSRNOT00000032408
hypothetical protein LOC680913
chr5_-_102743417 0.01 ENSRNOT00000067389
basonuclin 2
chr6_-_52401853 0.01 ENSRNOT00000075513
cadherin-related family member 3
chr13_+_99004942 0.01 ENSRNOT00000085390
acyl-CoA binding domain containing 3
chr1_-_224986291 0.01 ENSRNOT00000026284
TATA-box binding protein associated factor 6 like
chr15_+_108286453 0.01 ENSRNOT00000016986
UBA domain containing 2
chr12_+_25561777 0.01 ENSRNOT00000002032
RCC1 like
chr7_+_118490345 0.01 ENSRNOT00000046227
zinc finger protein 7-like
chr13_+_89774764 0.01 ENSRNOT00000005619
Rho GTPase activating protein 30
chr4_-_176381477 0.01 ENSRNOT00000048367
solute carrier organic anion transporter family, member 1a6
chr1_-_252116971 0.01 ENSRNOT00000035013
lipase, member O1
chr2_+_243656579 0.01 ENSRNOT00000036993
alcohol dehydrogenase 1 (class I)
chr6_+_123034304 0.01 ENSRNOT00000078938
candidate plasticity gene 1
chr3_+_141068023 0.01 ENSRNOT00000036527
kizuna centrosomal protein
chr7_-_14054639 0.01 ENSRNOT00000039852
ilvB acetolactate synthase like
chr1_+_204861566 0.01 ENSRNOT00000023214
family with sequence similarity 175, member B
chr19_-_37675077 0.01 ENSRNOT00000031033
enkurin domain containing 1
chr2_+_27365148 0.01 ENSRNOT00000021549
collagen type IV alpha 3 binding protein
chr15_-_33218456 0.01 ENSRNOT00000017753
ajuba LIM protein
chr4_+_118160147 0.01 ENSRNOT00000022014
family with sequence similarity 136, member A
chr9_+_79659251 0.01 ENSRNOT00000021656
X-ray repair cross complementing 5
chr2_+_243701962 0.01 ENSRNOT00000016891
alcohol dehydrogenase 4 (class II), pi polypeptide
chr1_-_80617057 0.01 ENSRNOT00000080453
apolipoprotein E
chr7_-_117070936 0.01 ENSRNOT00000048446
family with sequence similarity 83, member H
chr1_-_206282575 0.01 ENSRNOT00000024974
ADAM metallopeptidase domain 12
chr9_+_46996156 0.01 ENSRNOT00000019673
interleukin 1 receptor type 1
chr9_-_81879211 0.01 ENSRNOT00000085140
ring finger protein 25
chr9_+_42620006 0.01 ENSRNOT00000019966
heparan sulfate 6-O-sulfotransferase 1
chr12_-_37699616 0.01 ENSRNOT00000077803
similar to hypothetical protein FLJ38663
chr1_+_215628785 0.00 ENSRNOT00000054864
lymphocyte-specific protein 1
chr2_+_218834034 0.00 ENSRNOT00000018367
diphthamide biosynthesis 5
chr7_+_35069814 0.00 ENSRNOT00000089228
nuclear receptor subfamily 2, group C, member 1
chr15_+_108960562 0.00 ENSRNOT00000081906
ENSRNOT00000077482
propionyl-CoA carboxylase alpha subunit
chr1_+_101884276 0.00 ENSRNOT00000082917
transmembrane protein 143
chr16_-_81834945 0.00 ENSRNOT00000037806
coagulation factor VII
chr2_+_20857202 0.00 ENSRNOT00000078919
acyl-CoA thioesterase 12
chr3_+_140024043 0.00 ENSRNOT00000086409
Ras and Rab interactor 2
chrX_-_128268285 0.00 ENSRNOT00000009755
ENSRNOT00000081880
THO complex 2
chr1_+_101884019 0.00 ENSRNOT00000028650
transmembrane protein 143
chr1_+_225129097 0.00 ENSRNOT00000026938
echinoderm microtubule associated protein like 3
chr3_-_160922341 0.00 ENSRNOT00000029206
TP53 target 5
chr9_+_49647257 0.00 ENSRNOT00000021899
mitochondrial ribosomal protein S9
chr10_+_43538160 0.00 ENSRNOT00000089217
CCR4-NOT transcription complex, subunit 8
chr6_+_26537707 0.00 ENSRNOT00000050102
zinc finger protein 513
chr19_+_49637016 0.00 ENSRNOT00000016880
beta-carotene oxygenase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186)
0.0 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:0034443 plasma lipoprotein particle oxidation(GO:0034441) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0035338 fatty acid elongation, monounsaturated fatty acid(GO:0034625) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0070268 cuticle development(GO:0042335) cornification(GO:0070268)
0.0 0.0 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.0 0.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)