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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nr2f1_Nr4a1

Z-value: 0.74

Motif logo

Transcription factors associated with Nr2f1_Nr4a1

Gene Symbol Gene ID Gene Info
ENSRNOG00000014795 nuclear receptor subfamily 2, group F, member 1
ENSRNOG00000007607 nuclear receptor subfamily 4, group A, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2f1rn6_v1_chr2_-_5577369_5577369-0.503.9e-01Click!
Nr4a1rn6_v1_chr7_+_142905758_142905758-0.355.6e-01Click!

Activity profile of Nr2f1_Nr4a1 motif

Sorted Z-values of Nr2f1_Nr4a1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_123106694 0.70 ENSRNOT00000028829
oxytocin/neurophysin 1 prepropeptide
chr14_+_43694183 0.65 ENSRNOT00000046342
similar to ribosomal protein S23
chr18_-_26211445 0.40 ENSRNOT00000027739
neuronal regeneration related protein
chr3_+_147609095 0.38 ENSRNOT00000041456
sulfiredoxin 1
chr17_+_15845931 0.32 ENSRNOT00000092083
caspase recruitment domain family, member 19
chr1_+_101412736 0.31 ENSRNOT00000067468
luteinizing hormone beta polypeptide
chr1_+_242572533 0.29 ENSRNOT00000035123
transmembrane protein 252
chr12_+_47024442 0.28 ENSRNOT00000001545
cytochrome c oxidase subunit 6A1
chr8_+_118378059 0.26 ENSRNOT00000043247

chr10_-_40375605 0.26 ENSRNOT00000014464
annexin A6
chr1_+_31264755 0.26 ENSRNOT00000028988
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr4_+_78263866 0.25 ENSRNOT00000033807
expressed sequence AI854703
chr8_-_23014499 0.25 ENSRNOT00000017820
coiled-coil domain containing 151
chr4_+_170149029 0.23 ENSRNOT00000073287
histone H2A.J
chr5_+_50381244 0.23 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr5_-_166924136 0.22 ENSRNOT00000085251
splA/ryanodine receptor domain and SOCS box containing 1
chr10_-_71849293 0.22 ENSRNOT00000003799
LIM homeobox 1
chr12_-_40227297 0.21 ENSRNOT00000030600
family with sequence similarity 109, member A
chr7_-_121943121 0.21 ENSRNOT00000046460
ribosomal protein L26, pseudogene 1
chr1_+_267607416 0.21 ENSRNOT00000087894
ENSRNOT00000076367
ENSRNOT00000016851
glutathione S-transferase omega 2
glutathione S-transferase omega 1
chr2_-_140464607 0.20 ENSRNOT00000058190
NADH:ubiquinone oxidoreductase subunit C1
chr1_+_71416110 0.20 ENSRNOT00000084899
zinc finger protein 787
chr2_-_119140110 0.20 ENSRNOT00000058810

chr1_+_276659542 0.20 ENSRNOT00000019681
transcription factor 7 like 2
chr7_+_121311024 0.20 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr2_+_204512302 0.19 ENSRNOT00000021846
calsequestrin 2
chr10_+_110139783 0.19 ENSRNOT00000054939
solute carrier family 16 member 3
chr2_-_123396147 0.19 ENSRNOT00000079004
transient receptor potential cation channel, subfamily C, member 3
chr10_-_97756521 0.19 ENSRNOT00000045902
solute carrier family 16, member 6
chr2_+_187347602 0.18 ENSRNOT00000025384
nestin
chr4_-_77706994 0.18 ENSRNOT00000038517
zinc finger protein 777
chr19_-_37427989 0.18 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr20_-_5618254 0.18 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chrX_-_113584459 0.17 ENSRNOT00000025923
potassium voltage-gated channel subfamily E regulatory subunit 5
chr8_+_116094851 0.17 ENSRNOT00000084120
similar to RIKEN cDNA 6430571L13 gene; similar to g20 protein
chr6_-_135412312 0.17 ENSRNOT00000010610
ankyrin repeat domain 9
chr8_+_98745310 0.17 ENSRNOT00000019938
Zic family member 4
chr19_-_25166528 0.16 ENSRNOT00000007775
relaxin 3
chr4_-_148845267 0.16 ENSRNOT00000037397
transmembrane protein 72
chr12_-_30566032 0.15 ENSRNOT00000093378
glioblastoma amplified sequence
chr7_+_116090189 0.15 ENSRNOT00000081571
prostate stem cell antigen
chr20_+_29951637 0.15 ENSRNOT00000074387
rCG22048-like
chr1_-_222250980 0.15 ENSRNOT00000028734
nudix hydrolase 22
chr2_-_14701903 0.15 ENSRNOT00000051895
cytochrome c oxidase subunit 7C
chr1_-_192057612 0.15 ENSRNOT00000024471
NADH:ubiquinone oxidoreductase subunit AB1
chr20_-_3818045 0.15 ENSRNOT00000091622
hydroxysteroid (17-beta) dehydrogenase 8
chr19_+_52521809 0.14 ENSRNOT00000081019
kelch-like family member 36
chr2_+_119139717 0.14 ENSRNOT00000016051
NADH:ubiquinone oxidoreductase subunit B5
chr11_-_59110562 0.14 ENSRNOT00000047907
ENSRNOT00000042024
limbic system-associated membrane protein
chr10_-_15600858 0.14 ENSRNOT00000035459
hemoglobin, theta 1B
chr12_-_44174583 0.14 ENSRNOT00000001490
tescalcin
chr3_-_8766433 0.14 ENSRNOT00000021865
kynurenine aminotransferase 1
chr1_-_89488223 0.14 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr5_-_134927235 0.14 ENSRNOT00000016751
ubiquinol-cytochrome c reductase hinge protein
chr10_-_84976170 0.14 ENSRNOT00000013542
leucine rich repeat containing 46
chr8_+_48569328 0.13 ENSRNOT00000084030
coiled-coil domain containing 153
chr12_-_18526250 0.13 ENSRNOT00000001791
acetylserotonin O-methyltransferase
chr10_-_15235740 0.13 ENSRNOT00000027170
MAPK regulated co-repressor interacting protein 2
chr8_+_59900651 0.13 ENSRNOT00000020410
transmembrane protein 266
chr7_+_35125424 0.13 ENSRNOT00000085978
ENSRNOT00000010117
NADH:ubiquinone oxidoreductase subunit A12
chr7_-_12432130 0.13 ENSRNOT00000077301
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr19_+_10596960 0.13 ENSRNOT00000021769
cytokine induced apoptosis inhibitor 1
chr8_-_23000455 0.13 ENSRNOT00000091027
ENSRNOT00000017493
ral guanine nucleotide dissociation stimulator-like 3
chr5_-_168004724 0.13 ENSRNOT00000024711
Parkinsonism associated deglycase
chr6_-_136145837 0.13 ENSRNOT00000015122
creatine kinase B
chr5_-_154438361 0.13 ENSRNOT00000085003

chr14_+_84237520 0.12 ENSRNOT00000083580
galactose-3-O-sulfotransferase 1
chr9_+_61692154 0.12 ENSRNOT00000082300
heat shock protein family E member 1
chr10_-_38782419 0.12 ENSRNOT00000073964
ubiquinol-cytochrome c reductase, complex III subunit VII
chr14_-_84937725 0.12 ENSRNOT00000083839
ubiquinol-cytochrome c reductase, complex III subunit X
chr7_-_143793774 0.12 ENSRNOT00000079678
cysteine sulfinic acid decarboxylase
chr3_+_2480232 0.12 ENSRNOT00000014489
taperin
chr18_-_16542165 0.12 ENSRNOT00000079381
solute carrier family 39 member 6
chr11_+_30904733 0.12 ENSRNOT00000036027
melanocortin 2 receptor accessory protein
chr7_-_127081704 0.12 ENSRNOT00000055893
uncharacterized LOC108351584
chr1_-_31528083 0.12 ENSRNOT00000061041
ribosomal protein L26, pseudogene 2
chr1_-_24193567 0.12 ENSRNOT00000040736
serum/glucocorticoid regulated kinase 1
chr19_-_54245855 0.12 ENSRNOT00000023855
ER membrane protein complex subunit 8
chr4_-_82133605 0.12 ENSRNOT00000008023
homeobox A2
chr2_-_225107283 0.12 ENSRNOT00000055711
solute carrier family 44, member 3
chr15_+_2631529 0.12 ENSRNOT00000018897
catechol-O-methyltransferase domain containing 1
chr5_+_151436464 0.11 ENSRNOT00000012463
mitogen-activated protein kinase kinase kinase 6
chr5_+_150032999 0.11 ENSRNOT00000013301
serine and arginine rich splicing factor 4
chr2_-_243407608 0.11 ENSRNOT00000014631
microsomal triglyceride transfer protein
chr6_-_44363915 0.11 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr4_-_123118186 0.11 ENSRNOT00000038096
coiled-coil-helix-coiled-coil-helix domain containing 4
chr9_+_43259709 0.11 ENSRNOT00000022487
cytochrome c oxidase subunit 5B
chr9_-_43127887 0.11 ENSRNOT00000021685
ankyrin repeat domain 39
chr2_-_149088787 0.11 ENSRNOT00000064833
clarin 1
chr2_-_197991574 0.11 ENSRNOT00000085632
circadian associated repressor of transcription
chr1_-_7480825 0.11 ENSRNOT00000048754
phosphatase and actin regulator 2
chr8_-_130491998 0.10 ENSRNOT00000064114
HIG1 hypoxia inducible domain family, member 1A
chr3_+_113318563 0.10 ENSRNOT00000089230
creatine kinase, mitochondrial 1
chr9_+_17340341 0.10 ENSRNOT00000026637
ENSRNOT00000026559
ENSRNOT00000042790
ENSRNOT00000044163
ENSRNOT00000083811
vascular endothelial growth factor A
chr7_+_12229379 0.10 ENSRNOT00000060811
ADAMTS-like 5
chr6_+_126434226 0.10 ENSRNOT00000090857
chromogranin A
chr3_-_148428288 0.10 ENSRNOT00000072663
dual specificity phosphatase 15
chr4_+_169161585 0.10 ENSRNOT00000079785
epithelial membrane protein 1
chr11_+_72044096 0.10 ENSRNOT00000034757
SUMO1/sentrin specific peptidase 5
chr10_-_89958805 0.10 ENSRNOT00000084266
membrane palmitoylated protein 3
chr3_-_172566010 0.10 ENSRNOT00000071913
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr4_+_64088900 0.10 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr16_+_19097391 0.10 ENSRNOT00000018018
calreticulin 3
chr6_+_8669722 0.09 ENSRNOT00000048550
calmodulin-lysine N-methyltransferase
chr5_-_166926636 0.09 ENSRNOT00000023287
splA/ryanodine receptor domain and SOCS box containing 1
chr1_-_242083484 0.09 ENSRNOT00000065921
tight junction protein 2
chr6_+_23337571 0.09 ENSRNOT00000011832
similar to hypothetical protein MGC38716
chr1_+_89162639 0.09 ENSRNOT00000028508
ATPase H+/K+ transporting alpha subunit
chr12_-_30268990 0.09 ENSRNOT00000079546
vitamin K epoxide reductase complex subunit 1-like protein 1
chr1_-_84812486 0.09 ENSRNOT00000078369

chr6_-_6842758 0.09 ENSRNOT00000006094
potassium voltage-gated channel modifier subfamily G member 3
chr17_+_32904119 0.09 ENSRNOT00000059854
serpin family B member 1A
chr7_-_12311149 0.09 ENSRNOT00000046886
DAZ associated protein 1
chr10_-_56429748 0.09 ENSRNOT00000020675
ENSRNOT00000092704
spermatid maturation 1
chr5_-_75319189 0.09 ENSRNOT00000047200
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr10_+_74874130 0.09 ENSRNOT00000076050
ENSRNOT00000044226
ENSRNOT00000085052
ENSRNOT00000076196
septin 4
chr7_-_34485034 0.08 ENSRNOT00000007351
small nuclear ribonucleoprotein polypeptide F
chr5_-_59149625 0.08 ENSRNOT00000040641
ENSRNOT00000084216
sperm associated antigen 8
chr19_+_9024451 0.08 ENSRNOT00000073744
60S ribosomal protein L26-like
chr7_+_117951154 0.08 ENSRNOT00000060181
zinc finger protein 7
chr3_+_170252901 0.08 ENSRNOT00000005871
melanocortin 3 receptor
chrX_-_68562301 0.08 ENSRNOT00000076720
oligophrenin 1
chr5_+_173640780 0.08 ENSRNOT00000027476
PPARGC1 and ESRR induced regulator, muscle 1
chr20_-_30406295 0.08 ENSRNOT00000038537
unc-5 netrin receptor B
chr1_+_207508414 0.08 ENSRNOT00000054896
neuropeptide S
chr1_-_91042230 0.08 ENSRNOT00000073107
DNA-directed RNA polymerase II subunit RPB9
chr20_+_4824226 0.08 ENSRNOT00000001113
NFKB inhibitor like 1
chr20_+_5085712 0.08 ENSRNOT00000083284
abhydrolase domain containing 16A
chr1_+_224927764 0.08 ENSRNOT00000050814

chr1_-_80630038 0.08 ENSRNOT00000025281
translocase of outer mitochondrial membrane 40
chr6_-_106971250 0.08 ENSRNOT00000010926
double PHD fingers 3
chr10_+_109658032 0.08 ENSRNOT00000054965
mitochondrial ribosomal protein L12
chr2_-_123396386 0.08 ENSRNOT00000046700
transient receptor potential cation channel, subfamily C, member 3
chr9_-_9985630 0.08 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr18_+_74156553 0.08 ENSRNOT00000022892
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr11_-_32088002 0.08 ENSRNOT00000002732
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr3_+_61756148 0.08 ENSRNOT00000002134
metaxin 2
chr5_+_159484370 0.08 ENSRNOT00000010593
succinate dehydrogenase complex iron sulfur subunit B
chr8_-_118378460 0.08 ENSRNOT00000047247
similar to ribosomal protein S23
chr20_-_4489281 0.07 ENSRNOT00000031548
cytochrome P450, family 21, subfamily a, polypeptide 1
chr10_+_56662561 0.07 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr9_+_10535340 0.07 ENSRNOT00000075408
zinc and ring finger 4
chr20_+_26534535 0.07 ENSRNOT00000000423
transmembrane protein 167B
chr16_-_81243757 0.07 ENSRNOT00000024677
growth arrest specific 6
chr9_-_92291220 0.07 ENSRNOT00000093357
delta/notch-like EGF repeat containing
chr5_-_157573183 0.07 ENSRNOT00000064418
mitochondrial inner membrane organizing system 1
chr9_-_10441834 0.07 ENSRNOT00000043704
ribosomal protein L36
chr10_+_56662242 0.07 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr7_+_11724962 0.07 ENSRNOT00000026551
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr19_+_54245950 0.07 ENSRNOT00000024033
cytochrome c oxidase subunit 4i1
chr10_-_89959176 0.07 ENSRNOT00000028264
membrane palmitoylated protein 3
chr17_-_389967 0.07 ENSRNOT00000023865
fructose-bisphosphatase 2
chr1_+_141550633 0.07 ENSRNOT00000020047
mesoderm posterior bHLH transcription factor 2
chr5_-_56576676 0.07 ENSRNOT00000029712
NADH:ubiquinone oxidoreductase subunit B6
chr11_+_64472072 0.07 ENSRNOT00000042756
similar to ribosomal protein L27
chr10_-_91448477 0.07 ENSRNOT00000038836
Rho GTPase activating protein 27
chr6_+_126170911 0.07 ENSRNOT00000077477
Ras and Rab interactor 3
chr1_+_213595240 0.06 ENSRNOT00000017137
secretoglobin, family 1C, member 1
chr14_-_79464770 0.06 ENSRNOT00000008932
GrpE-like 1, mitochondrial
chr7_-_117978787 0.06 ENSRNOT00000074262
zinc finger protein 647
chr4_-_100232559 0.06 ENSRNOT00000016984
vesicle-associated membrane protein 5
chr15_+_48789165 0.06 ENSRNOT00000044562
zinc finger protein 395
chr1_-_262013619 0.06 ENSRNOT00000021278
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr11_+_37798370 0.06 ENSRNOT00000002679
beta-site APP-cleaving enzyme 2
chr12_-_23624212 0.06 ENSRNOT00000064405
ENSRNOT00000001943
RAS p21 protein activator 4
chr14_-_8548310 0.06 ENSRNOT00000092436
Rho GTPase activating protein 24
chr3_+_81287242 0.06 ENSRNOT00000086530
peroxisomal biogenesis factor 16
chr5_-_160179978 0.06 ENSRNOT00000022820
solute carrier family 25, member 34
chr3_-_123702732 0.06 ENSRNOT00000028859
similar to RIKEN cDNA 1700037H04
chr7_-_144960527 0.06 ENSRNOT00000086554
zinc finger protein 385A
chr4_-_130659697 0.06 ENSRNOT00000072374
rCG56280-like
chr9_-_9702306 0.06 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chr13_-_89518939 0.06 ENSRNOT00000004228
succinate dehydrogenase complex subunit C
chr6_+_107581608 0.06 ENSRNOT00000058101
acyl-CoA thioesterase 6
chr4_+_122781095 0.06 ENSRNOT00000008962
histone deacetylase 11
chr10_-_45923829 0.06 ENSRNOT00000035285
olfactory receptor 1462
chr8_+_117679278 0.06 ENSRNOT00000042114
ubiquinol-cytochrome c reductase core protein I
chr19_-_56677084 0.06 ENSRNOT00000024084
actin, alpha 1, skeletal muscle
chr16_-_8350067 0.06 ENSRNOT00000026932
mitochondrial import inner membrane translocase subunit Tim23-like
chr1_+_261158261 0.06 ENSRNOT00000071965
phosphoglycerate mutase 1
chr2_-_187401786 0.06 ENSRNOT00000025624
hyaluronan and proteoglycan link protein 2
chr8_+_117280705 0.06 ENSRNOT00000085038
ubiquitin specific peptidase 19
chr10_+_37724915 0.06 ENSRNOT00000008477
voltage-dependent anion channel 1
chr5_+_134927609 0.06 ENSRNOT00000018506
leucine rich repeat containing 41
chr7_+_144052061 0.06 ENSRNOT00000020103
ENSRNOT00000091378
anti-Mullerian hormone receptor type 2
chr19_-_14945302 0.06 ENSRNOT00000079391

chr12_-_29952196 0.06 ENSRNOT00000086175
transmembrane protein 248
chrX_+_110818716 0.06 ENSRNOT00000086308
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_197813963 0.06 ENSRNOT00000045531
ribosomal protein L36-like
chr14_+_60764409 0.06 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr7_-_118518193 0.06 ENSRNOT00000075636
zinc finger protein 250-like
chrX_-_123662350 0.06 ENSRNOT00000092624
septin 6
chr9_-_81565416 0.06 ENSRNOT00000083582
angio-associated, migratory cell protein
chr7_+_120380544 0.06 ENSRNOT00000015009
RNA polymerase II subunit F
chr5_-_174921 0.06 ENSRNOT00000056239
TIMELESS interacting protein like 1
chr9_+_20213776 0.06 ENSRNOT00000071439
triosephosphate isomerase-like
chr4_+_161696903 0.06 ENSRNOT00000055889
rCG30099-like
chr1_-_263762785 0.05 ENSRNOT00000018221
carboxypeptidase N subunit 1
chr20_-_3819200 0.05 ENSRNOT00000000542
ENSRNOT00000081486
hydroxysteroid (17-beta) dehydrogenase 8
chr10_+_77537340 0.05 ENSRNOT00000003297
transmembrane protein 100

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2f1_Nr4a1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.1 0.2 GO:0060066 oviduct development(GO:0060066)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) embryonic hindgut morphogenesis(GO:0048619)
0.1 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.4 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.2 GO:0045105 intermediate filament polymerization or depolymerization(GO:0045105)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186)
0.0 0.1 GO:0045560 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0021539 subthalamus development(GO:0021539)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948) positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0002339 B cell selection(GO:0002339) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.0 GO:0036023 embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.2 GO:0006590 thyroid hormone generation(GO:0006590) follicle-stimulating hormone secretion(GO:0046884)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0021627 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.0 0.0 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.4 GO:0030823 regulation of cGMP metabolic process(GO:0030823)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0045273 respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0032173 septin collar(GO:0032173)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0031105 septin complex(GO:0031105) sperm annulus(GO:0097227)
0.0 0.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.2 GO:0030614 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.0 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.0 GO:0046911 metal chelating activity(GO:0046911)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport