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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nr2c2
Z-value: 0.40
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Transcription factors associated with Nr2c2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nr2c2 | rn6_v1_chr4_+_124005280_124005280 | 0.41 | 5.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_13778178 Show fit | 0.36 |
ENSRNOT00000058314
|
glutathione S-transferase, theta 4 |
|
| chr12_-_18526250 Show fit | 0.29 |
ENSRNOT00000001791
|
acetylserotonin O-methyltransferase |
|
| chr10_+_59533480 Show fit | 0.28 |
ENSRNOT00000087723
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
|
| chr6_+_43001948 Show fit | 0.23 |
ENSRNOT00000007374
|
hippocalcin-like 1 |
|
| chr16_-_20890949 Show fit | 0.22 |
ENSRNOT00000081977
|
homer scaffolding protein 3 |
|
| chr1_-_226049929 Show fit | 0.20 |
ENSRNOT00000007320
|
bestrophin 1 |
|
| chr16_-_59366824 Show fit | 0.19 |
ENSRNOT00000015062
|
similar to 6430573F11Rik protein |
|
| chr3_-_7498555 Show fit | 0.19 |
ENSRNOT00000017725
|
BarH-like homeobox 1 |
|
| chr5_-_156734541 Show fit | 0.19 |
ENSRNOT00000021036
|
cytidine deaminase-like |
|
| chr2_-_225107283 Show fit | 0.16 |
ENSRNOT00000055711
|
solute carrier family 44, member 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nr2c2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0030186 | melatonin metabolic process(GO:0030186) |
| 0.1 | 0.2 | GO:0046087 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.0 | 0.2 | GO:2000611 | positive regulation of thyroid hormone generation(GO:2000611) |
| 0.0 | 0.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.2 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.0 | 0.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.0 | 0.2 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 0.1 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
| 0.0 | 0.1 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.0 | 0.1 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.0 | 0.1 | GO:0032173 | septin collar(GO:0032173) |
| 0.0 | 0.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.1 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.0 | 0.1 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.0 | GO:0055087 | Ski complex(GO:0055087) |
| 0.0 | 0.0 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.0 | 0.0 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.2 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 0.2 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.2 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.1 | GO:0031770 | growth hormone-releasing hormone receptor binding(GO:0031770) |
| 0.0 | 0.1 | GO:0019807 | aspartoacylase activity(GO:0019807) |
| 0.0 | 0.1 | GO:0017168 | 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168) |
| 0.0 | 0.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |