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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nr1i2
Z-value: 0.50
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Transcription factors associated with Nr1i2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nr1i2 | rn6_v1_chr11_+_65022100_65022100 | -0.69 | 2.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_58771908 Show fit | 0.27 |
ENSRNOT00000018808
|
similar to 4933427D14Rik protein |
|
| chr8_-_84506328 Show fit | 0.21 |
ENSRNOT00000064754
|
muscular LMNA-interacting protein |
|
| chr9_-_14599594 Show fit | 0.19 |
ENSRNOT00000018138
|
triggering receptor expressed on myeloid cells-like 1 |
|
| chr8_+_26652121 Show fit | 0.18 |
ENSRNOT00000009342
|
endonuclease/exonuclease/phosphatase family domain containing 1 |
|
| chrX_+_156873849 Show fit | 0.18 |
ENSRNOT00000085410
|
Rho GTPase activating protein 4 |
|
| chr1_+_141767940 Show fit | 0.18 |
ENSRNOT00000064034
|
zinc finger protein 710 |
|
| chr6_+_29518416 Show fit | 0.16 |
ENSRNOT00000078660
|
|
|
| chr13_-_111948753 Show fit | 0.16 |
ENSRNOT00000048074
|
hydroxysteroid 11-beta dehydrogenase 1 |
|
| chr8_-_119889661 Show fit | 0.15 |
ENSRNOT00000011780
|
SH3 and cysteine rich domain |
|
| chr1_+_166125474 Show fit | 0.15 |
ENSRNOT00000091822
|
FCH and double SH3 domains 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nr1i2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0006713 | glucocorticoid catabolic process(GO:0006713) |
| 0.0 | 0.2 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 0.0 | 0.2 | GO:0034625 | fatty acid elongation, monounsaturated fatty acid(GO:0034625) |
| 0.0 | 0.2 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
| 0.0 | 0.1 | GO:1905006 | positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006) |
| 0.0 | 0.1 | GO:0007356 | thorax and anterior abdomen determination(GO:0007356) |
| 0.0 | 0.1 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.0 | 0.1 | GO:1900135 | positive regulation of renin secretion into blood stream(GO:1900135) |
| 0.0 | 0.1 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
| 0.0 | 0.1 | GO:0043132 | phospholipid transfer to membrane(GO:0006649) NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.0 | 0.1 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 0.1 | GO:0032059 | bleb(GO:0032059) |
| 0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.1 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.1 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 0.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.0 | 0.1 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.2 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.0 | 0.2 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.2 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.1 | GO:0033222 | xylose binding(GO:0033222) |
| 0.0 | 0.1 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.0 | 0.1 | GO:0015065 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 0.0 | 0.1 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.0 | 0.1 | GO:0015489 | polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489) |
| 0.0 | 0.1 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |