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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nkx6-2

Z-value: 0.23

Motif logo

Transcription factors associated with Nkx6-2

Gene Symbol Gene ID Gene Info
ENSRNOG00000017748 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx6-2rn6_v1_chr1_-_211923929_211923929-0.692.0e-01Click!

Activity profile of Nkx6-2 motif

Sorted Z-values of Nkx6-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_21970103 0.08 ENSRNOT00000074210

chr14_+_104250617 0.07 ENSRNOT00000079874
sprouty-related, EVH1 domain containing 2
chr19_+_27603307 0.07 ENSRNOT00000074702

chr10_-_104482838 0.06 ENSRNOT00000007246
RecQ like helicase 5
chr3_+_113918629 0.06 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr6_-_76552559 0.05 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr15_+_87722221 0.05 ENSRNOT00000082688
sciellin
chr18_+_1723565 0.05 ENSRNOT00000033468
growth regulation by estrogen in breast cancer 1 like
chr10_+_65552897 0.04 ENSRNOT00000056217
sperm associated antigen 5
chr5_+_173447784 0.04 ENSRNOT00000027251
TNF receptor superfamily member 4
chr8_+_23398030 0.04 ENSRNOT00000031893
similar to RIKEN cDNA 9530077C05
chr7_-_122644054 0.04 ENSRNOT00000025941
DnaJ heat shock protein family (Hsp40) member B7
chr2_+_210045161 0.04 ENSRNOT00000024455
solute carrier family 16, member 4
chr11_-_62451149 0.04 ENSRNOT00000093686
ENSRNOT00000081443
zinc finger and BTB domain containing 20
chr1_-_64147251 0.04 ENSRNOT00000088502
CCR4-NOT transcription complex, subunit 3
chr2_-_96509424 0.03 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr18_+_30904498 0.03 ENSRNOT00000026969
protocadherin gamma subfamily A, 11
chr2_-_188559882 0.03 ENSRNOT00000088199
tripartite motif-containing 46
chr6_+_86872903 0.03 ENSRNOT00000086894
Fanconi anemia, complementation group M
chr9_+_73378057 0.03 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr3_+_112390106 0.03 ENSRNOT00000081197
similar to Centrosomal protein of 27 kDa (Cep27 protein)
chr13_-_111972603 0.03 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr8_+_115546893 0.03 ENSRNOT00000018932
DDB1 and CUL4 associated factor 1
chr3_-_7796385 0.03 ENSRNOT00000082489
netrin G2
chr16_-_10802512 0.03 ENSRNOT00000079554
bone morphogenetic protein receptor type 1A
chr4_-_150522351 0.02 ENSRNOT00000079053
zinc finger protein 9
chr2_+_198726118 0.02 ENSRNOT00000056237
limb and CNS expressed 1 like
chr3_+_48082935 0.02 ENSRNOT00000087711
ENSRNOT00000067545
solute carrier family 4 member 10
chr3_+_56030915 0.02 ENSRNOT00000010489
phosphatase, orphan 2
chr4_+_88694583 0.02 ENSRNOT00000009202
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr7_-_11223649 0.02 ENSRNOT00000061191
major facilitator superfamily domain containing 12
chr13_-_52413681 0.02 ENSRNOT00000037100
ENSRNOT00000011801
neuron navigator 1
chr18_+_29124428 0.02 ENSRNOT00000073131
IgA-inducing protein
chr10_-_43599232 0.02 ENSRNOT00000044299
gem (nuclear organelle) associated protein 5
chr17_+_35435079 0.02 ENSRNOT00000074800
exocyst complex component 2
chr14_+_63095720 0.02 ENSRNOT00000006071
PPARG coactivator 1 alpha
chr13_-_104284068 0.02 ENSRNOT00000005407
uncharacterized LOC100912365
chr7_-_68512397 0.02 ENSRNOT00000058036
solute carrier family 16 member 7
chr13_-_47916185 0.02 ENSRNOT00000087793
dual specificity tyrosine phosphorylation regulated kinase 3
chr17_-_53915076 0.02 ENSRNOT00000010836
AT-rich interaction domain 4B
chr3_-_48831417 0.02 ENSRNOT00000009920
ENSRNOT00000085246
potassium voltage-gated channel subfamily H member 7
chr6_-_98606109 0.02 ENSRNOT00000006860
WD repeat domain 89
chr5_+_4373626 0.02 ENSRNOT00000064946
EYA transcriptional coactivator and phosphatase 1
chr9_+_1313209 0.02 ENSRNOT00000083387
TBC1 domain family, member 5
chr17_+_9596957 0.02 ENSRNOT00000017349
family with sequence similarity 193, member B
chr4_-_135069970 0.02 ENSRNOT00000008221
contactin 3
chr5_-_166116516 0.02 ENSRNOT00000079919
ENSRNOT00000080888
kinesin family member 1B
chr8_+_85503224 0.02 ENSRNOT00000012348
glutathione S-transferase alpha 4
chr17_+_34704616 0.02 ENSRNOT00000090706
ENSRNOT00000083674
ENSRNOT00000077110
exocyst complex component 2
chr18_-_77535564 0.02 ENSRNOT00000041380
ENSRNOT00000090265
ATPase phospholipid transporting 9B (putative)
chr16_+_46731403 0.02 ENSRNOT00000017624
teneurin transmembrane protein 3
chr6_+_129621070 0.02 ENSRNOT00000091338
poly (A) polymerase alpha
chr9_+_53546018 0.01 ENSRNOT00000016842
inositol polyphosphate-1-phosphatase
chr4_-_51931112 0.01 ENSRNOT00000080575
protection of telomeres 1
chr18_-_26211445 0.01 ENSRNOT00000027739
neuronal regeneration related protein
chr15_+_56666012 0.01 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr3_-_56030744 0.01 ENSRNOT00000089637
coiled-coil domain containing 173
chrX_+_22342308 0.01 ENSRNOT00000079909
ENSRNOT00000087945
ENSRNOT00000077528
lysine demethylase 5C
chr7_+_64769089 0.01 ENSRNOT00000088861
glutamate receptor interacting protein 1
chr4_+_162281574 0.01 ENSRNOT00000087850
C-type lectin domain family 2, member D
chr18_+_30496318 0.01 ENSRNOT00000027179
protocadherin beta 11
chr3_+_8430829 0.01 ENSRNOT00000090440
ENSRNOT00000060969
cerebral endothelial cell adhesion molecule
chrX_-_25590048 0.01 ENSRNOT00000004873
midline 1
chr14_+_34455934 0.01 ENSRNOT00000085991
ENSRNOT00000002981
clock circadian regulator
chr1_+_100577056 0.01 ENSRNOT00000026992
napsin A aspartic peptidase
chr16_-_10661528 0.01 ENSRNOT00000085012
family with sequence similarity 35, member A
chr14_-_72025137 0.01 ENSRNOT00000080604
C1q and tumor necrosis factor related protein 7
chr13_+_80464348 0.01 ENSRNOT00000076324
vesicle-associated membrane protein 4
chr8_-_109621408 0.01 ENSRNOT00000087398
protein phosphatase 2, regulatory subunit B'', alpha
chr2_+_92559929 0.01 ENSRNOT00000033404
GTPase activating protein testicular GAP1
chr16_+_32449116 0.01 ENSRNOT00000050549
chloride voltage-gated channel 3
chr11_-_25456836 0.01 ENSRNOT00000085444
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr3_+_152294656 0.01 ENSRNOT00000027067
PHD finger protein 20
chr12_+_41316764 0.01 ENSRNOT00000090867
2'-5'-oligoadenylate synthetase 3
chr7_-_132143470 0.01 ENSRNOT00000038946
ENSRNOT00000044092
ENSRNOT00000066528
ENSRNOT00000045553
ENSRNOT00000046744
ENSRNOT00000055742
kinesin family member 21A
chr5_+_133819726 0.01 ENSRNOT00000081075
Scl/Tal1 interrupting locus
chr1_-_251387002 0.01 ENSRNOT00000092063
ATPase family, AAA domain containing 1
chr20_+_41266566 0.01 ENSRNOT00000000653
fyn-related Src family tyrosine kinase
chr14_-_72122158 0.01 ENSRNOT00000064495
C1q and tumor necrosis factor related protein 7
chrX_-_63291371 0.01 ENSRNOT00000082421
eukaryotic translation initiation factor 2 subunit gamma
chr3_-_113423473 0.01 ENSRNOT00000064982
serine incorporator 4
chr3_-_104018861 0.01 ENSRNOT00000008387
cholinergic receptor, muscarinic 5
chr20_+_49319307 0.01 ENSRNOT00000057078
autophagy related 5
chr7_-_40315377 0.01 ENSRNOT00000091319
ENSRNOT00000036141
similar to RIKEN cDNA C430008C19
chr2_+_127459012 0.01 ENSRNOT00000093685
ENSRNOT00000072675
inturned planar cell polarity protein
chr12_-_51877624 0.01 ENSRNOT00000056800
checkpoint kinase 2
chr19_-_37528011 0.01 ENSRNOT00000059628
agouti related neuropeptide
chr2_-_128675408 0.01 ENSRNOT00000019256
sodium channel and clathrin linker 1
chr10_+_38661901 0.01 ENSRNOT00000009098
zinc finger CCHC-type containing 10
chr6_-_38007162 0.01 ENSRNOT00000044583

chr3_-_48604097 0.01 ENSRNOT00000009620
interferon induced with helicase C domain 1
chrX_+_124631881 0.01 ENSRNOT00000009329
ATPase Na+/K+ transporting family member beta 4
chr9_+_73334618 0.01 ENSRNOT00000092717
microtubule-associated protein 2
chr8_+_85259982 0.01 ENSRNOT00000010409
ELOVL fatty acid elongase 5
chr6_+_108009251 0.01 ENSRNOT00000059073
prostaglandin reductase 2
chr15_-_88036354 0.01 ENSRNOT00000014747
endothelin receptor type B
chrX_+_110016995 0.00 ENSRNOT00000093542
Nik related kinase
chrX_+_157759624 0.00 ENSRNOT00000003192
similar to motile sperm domain containing 1
chr19_-_11669578 0.00 ENSRNOT00000026373
G protein subunit alpha o1
chr4_-_66955732 0.00 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr1_-_67284864 0.00 ENSRNOT00000082908
similar to zinc finger and SCAN domain containing 4
chrX_-_138237157 0.00 ENSRNOT00000003414
RAP2C, member of RAS oncogene family
chr6_-_95934296 0.00 ENSRNOT00000034338
SIX homeobox 1
chr13_+_67545430 0.00 ENSRNOT00000003405
phosducin
chr11_-_44292884 0.00 ENSRNOT00000084060
discoidin, CUB and LCCL domain containing 2
chr3_+_55960067 0.00 ENSRNOT00000010216
peptidylprolyl isomerase G
chr3_-_113423149 0.00 ENSRNOT00000021008
serine incorporator 4
chr16_-_930527 0.00 ENSRNOT00000014787
spindlin 1
chr10_+_104483042 0.00 ENSRNOT00000007362
SAP30 binding protein
chr2_+_41442241 0.00 ENSRNOT00000067546
phosphodiesterase 4D
chr10_+_63635219 0.00 ENSRNOT00000081813
ENSRNOT00000005016
pre-mRNA processing factor 8
chr8_+_85355766 0.00 ENSRNOT00000010583
glial cells missing homolog 1
chr10_+_56445647 0.00 ENSRNOT00000056870
transmembrane protein 256
chr2_+_128675814 0.00 ENSRNOT00000058366
similar to protein C33A12.3
chr4_-_163762434 0.00 ENSRNOT00000081854
immunoreceptor Ly49si1
chr8_+_116657371 0.00 ENSRNOT00000024966
MON1 homolog A, secretory trafficking associated
chr3_-_60611924 0.00 ENSRNOT00000068745
chimerin 1
chr5_-_102743417 0.00 ENSRNOT00000067389
basonuclin 2
chr11_-_71757801 0.00 ENSRNOT00000029572
single-pass membrane protein with coiled-coil domains 1
chr1_-_231530690 0.00 ENSRNOT00000087140
ENSRNOT00000018452
ENSRNOT00000018272
transducin-like enhancer of split 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)