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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nkx3-2
Z-value: 0.60
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Transcription factors associated with Nkx3-2
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_260596777 Show fit | 0.43 |
ENSRNOT00000009370
|
LIM homeobox 8 |
|
| chr6_+_8886591 Show fit | 0.41 |
ENSRNOT00000091510
ENSRNOT00000089174 |
SIX homeobox 3 |
|
| chr14_-_37770059 Show fit | 0.33 |
ENSRNOT00000029721
|
solute carrier family 10, member 4 |
|
| chr10_-_15577977 Show fit | 0.31 |
ENSRNOT00000052292
|
hemoglobin alpha, adult chain 3 |
|
| chr5_-_17061361 Show fit | 0.25 |
ENSRNOT00000089318
|
proenkephalin |
|
| chr8_+_48569328 Show fit | 0.25 |
ENSRNOT00000084030
|
coiled-coil domain containing 153 |
|
| chr10_+_110138586 Show fit | 0.24 |
ENSRNOT00000086096
|
solute carrier family 16 member 3 |
|
| chr5_-_17061837 Show fit | 0.23 |
ENSRNOT00000011892
|
proenkephalin |
|
| chr1_+_79894450 Show fit | 0.21 |
ENSRNOT00000057963
|
nanos C2HC-type zinc finger 2 |
|
| chr9_+_20004280 Show fit | 0.21 |
ENSRNOT00000075670
|
ankyrin repeat domain 66 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nkx3-2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0051867 | general adaptation syndrome, behavioral process(GO:0051867) |
| 0.1 | 0.4 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.0 | 0.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 0.3 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 0.2 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.0 | 0.2 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 0.0 | 0.1 | GO:1904685 | positive regulation of metalloendopeptidase activity(GO:1904685) |
| 0.0 | 0.1 | GO:0052047 | calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201) |
| 0.0 | 0.1 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 0.0 | 0.1 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 0.4 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 0.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 0.2 | GO:0031105 | septin complex(GO:0031105) sperm annulus(GO:0097227) |
| 0.0 | 0.1 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.0 | 0.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 0.3 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.0 | 0.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 0.2 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.1 | GO:0046573 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.0 | 0.1 | GO:0035473 | lipase binding(GO:0035473) |
| 0.0 | 0.1 | GO:0045340 | mercury ion binding(GO:0045340) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |