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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nkx2-9
Z-value: 0.46
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Transcription factors associated with Nkx2-9
| Gene Symbol | Gene ID | Gene Info |
|---|
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_28654733 Show fit | 0.81 |
ENSRNOT00000006174
|
pro-melanin-concentrating hormone |
|
| chr1_+_33910912 Show fit | 0.24 |
ENSRNOT00000044690
|
iroquois homeobox 1 |
|
| chr1_-_7801438 Show fit | 0.17 |
ENSRNOT00000022273
|
|
|
| chr5_+_50381244 Show fit | 0.17 |
ENSRNOT00000012385
|
glycoprotein hormones, alpha polypeptide |
|
| chr1_+_279798187 Show fit | 0.15 |
ENSRNOT00000024065
|
pancreatic lipase |
|
| chr5_-_127273656 Show fit | 0.14 |
ENSRNOT00000057341
|
DMRT-like family B with proline-rich C-terminal, 1 |
|
| chr7_-_119441487 Show fit | 0.13 |
ENSRNOT00000067635
|
parvalbumin |
|
| chr8_-_61917125 Show fit | 0.11 |
ENSRNOT00000085049
|
similar to human chromosome 15 open reading frame 39 |
|
| chr10_-_87407634 Show fit | 0.11 |
ENSRNOT00000016657
|
keratin 23 |
|
| chr3_+_161018511 Show fit | 0.11 |
ENSRNOT00000019804
ENSRNOT00000039664 |
WAP four-disulfide core domain 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nkx2-9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.1 | 0.2 | GO:0072268 | specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268) |
| 0.0 | 0.2 | GO:0046884 | thyroid hormone generation(GO:0006590) follicle-stimulating hormone secretion(GO:0046884) |
| 0.0 | 0.1 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.0 | 0.1 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 0.0 | 0.1 | GO:0009804 | coumarin metabolic process(GO:0009804) negative regulation of superoxide anion generation(GO:0032929) |
| 0.0 | 0.1 | GO:0061365 | positive regulation of triglyceride lipase activity(GO:0061365) |
| 0.0 | 0.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.0 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 0.1 | GO:0046573 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.0 | 0.1 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.0 | 0.0 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |