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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nkx2-3
Z-value: 0.54
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Transcription factors associated with Nkx2-3
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_56766475 Show fit | 0.25 |
ENSRNOT00000078819
|
Sp5 transcription factor |
|
| chr7_+_42304534 Show fit | 0.17 |
ENSRNOT00000085097
|
KIT ligand |
|
| chr2_+_41467064 Show fit | 0.16 |
ENSRNOT00000073231
|
|
|
| chr13_+_87986240 Show fit | 0.15 |
ENSRNOT00000003705
|
regulator of G-protein signaling 5 |
|
| chr1_+_256382791 Show fit | 0.12 |
ENSRNOT00000022549
|
cytochrome P450, family 26, subfamily a, polypeptide 1 |
|
| chr2_-_138833933 Show fit | 0.11 |
ENSRNOT00000013343
|
protocadherin 18 |
|
| chr9_+_25410669 Show fit | 0.11 |
ENSRNOT00000030912
ENSRNOT00000090920 |
transcription factor AP-2 beta |
|
| chr7_+_41475163 Show fit | 0.10 |
ENSRNOT00000037844
|
dual specificity phosphatase 6 |
|
| chr9_-_30844199 Show fit | 0.10 |
ENSRNOT00000017169
|
collagen type XIX alpha 1 chain |
|
| chr9_-_121725716 Show fit | 0.10 |
ENSRNOT00000087405
|
adenylate cyclase activating polypeptide 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nkx2-3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0070662 | negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668) |
| 0.0 | 0.1 | GO:0002877 | regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) |
| 0.0 | 0.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.0 | 0.1 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 0.0 | 0.1 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.0 | 0.1 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.0 | 0.1 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.0 | 0.1 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
| 0.0 | 0.1 | GO:1901367 | response to L-cysteine(GO:1901367) |
| 0.0 | 0.1 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0043511 | inhibin complex(GO:0043511) |
| 0.0 | 0.1 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.0 | 0.1 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 0.0 | 0.0 | GO:1990836 | lysosomal matrix(GO:1990836) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.0 | 0.1 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.0 | 0.1 | GO:0003921 | GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922) |
| 0.0 | 0.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 0.1 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.0 | 0.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 0.0 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.0 | 0.0 | GO:0008948 | oxaloacetate decarboxylase activity(GO:0008948) |
| 0.0 | 0.0 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) prolactin receptor binding(GO:0005148) |
| 0.0 | 0.0 | GO:0046848 | hydroxyapatite binding(GO:0046848) |