Project
GSE49485: Hypoxia transcriptome sequencing of rat brain.
Navigation
Downloads
Results for Nhlh1
Z-value: 1.45
Motif logo
Transcription factors associated with Nhlh1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nhlh1 | rn6_v1_chr13_-_90443157_90443157 | 0.51 | 3.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_20807070 Show fit | 2.02 |
ENSRNOT00000072536
|
cartilage oligomeric matrix protein |
|
| chr10_+_59529785 Show fit | 1.68 |
ENSRNOT00000064840
ENSRNOT00000065181 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
|
| chr5_-_21345805 Show fit | 1.39 |
ENSRNOT00000081296
ENSRNOT00000007802 |
carbonic anhydrase 8 |
|
| chr4_+_86275717 Show fit | 1.32 |
ENSRNOT00000016414
|
protein phosphatase 1, regulatory subunit 17 |
|
| chr7_-_3342491 Show fit | 1.31 |
ENSRNOT00000081756
|
retinol dehydrogenase 5 |
|
| chr4_-_150244372 Show fit | 1.14 |
ENSRNOT00000047685
|
ret proto-oncogene |
|
| chr6_-_99783047 Show fit | 1.07 |
ENSRNOT00000009028
|
spectrin, beta, erythrocytic |
|
| chr10_+_23914894 Show fit | 0.96 |
ENSRNOT00000071435
|
early B-cell factor 1 |
|
| chr14_+_4362717 Show fit | 0.87 |
ENSRNOT00000002887
|
BarH-like homeobox 2 |
|
| chrX_-_111942749 Show fit | 0.84 |
ENSRNOT00000087583
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of Nhlh1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.0 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.1 | 2.0 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.0 | 1.4 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.9 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.2 | 0.8 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
| 0.0 | 0.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.7 | GO:0046599 | regulation of centriole replication(GO:0046599) |
| 0.0 | 0.7 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.0 | 0.7 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.2 | 0.6 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 1.5 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 1.1 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 1.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 0.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.1 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.4 | 2.0 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 1.3 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.1 | 1.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 1.2 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 1.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 1.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 0.8 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.0 | 0.8 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 1.3 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.8 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.8 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.5 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.5 | PID BARD1 PATHWAY | BARD1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 2.0 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 1.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 0.9 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.0 | 0.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.9 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.9 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.7 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.0 | 0.7 | REACTOME GABA B RECEPTOR ACTIVATION | Genes involved in GABA B receptor activation |
| 0.0 | 0.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |