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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nfil3_Tef
Z-value: 1.01
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Transcription factors associated with Nfil3_Tef
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfil3 | rn6_v1_chr17_+_12261102_12261102 | -0.83 | 8.3e-02 | Click! |
| Tef | rn6_v1_chr7_+_123043503_123043584 | 0.65 | 2.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_-_168123395 Show fit | 0.54 |
ENSRNOT00000024932
|
period circadian clock 3 |
|
| chr18_-_26211445 Show fit | 0.44 |
ENSRNOT00000027739
|
neuronal regeneration related protein |
|
| chr6_+_43743702 Show fit | 0.43 |
ENSRNOT00000082570
|
grainyhead-like transcription factor 1 |
|
| chr3_+_95715193 Show fit | 0.43 |
ENSRNOT00000089525
|
paired box 6 |
|
| chr6_-_105160470 Show fit | 0.41 |
ENSRNOT00000008367
|
a disintegrin and metalloprotease domain 4 |
|
| chr10_-_16752205 Show fit | 0.40 |
ENSRNOT00000079462
|
CREB3 regulatory factor |
|
| chrX_-_10218583 Show fit | 0.40 |
ENSRNOT00000013382
|
nyctalopin |
|
| chr15_-_47442664 Show fit | 0.37 |
ENSRNOT00000072994
|
protease, serine, 55 |
|
| chr15_+_40665041 Show fit | 0.34 |
ENSRNOT00000018300
|
APC membrane recruitment protein 2 |
|
| chr5_-_7941822 Show fit | 0.33 |
ENSRNOT00000079917
|
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nfil3_Tef
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0045187 | regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.1 | 0.4 | GO:1904937 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
| 0.1 | 0.4 | GO:1902211 | regulation of prolactin signaling pathway(GO:1902211) |
| 0.0 | 0.4 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
| 0.0 | 0.4 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.0 | 0.3 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.3 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.0 | 0.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.0 | 0.3 | GO:2000505 | regulation of energy homeostasis(GO:2000505) |
| 0.1 | 0.2 | GO:0019086 | late viral transcription(GO:0019086) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.2 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.2 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.0 | 0.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 0.2 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 0.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.1 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 0.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.2 | GO:0043398 | HLH domain binding(GO:0043398) |
| 0.1 | 0.2 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.0 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 0.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.0 | 0.2 | GO:0019992 | diacylglycerol binding(GO:0019992) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |