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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nfe2l2
Z-value: 0.54
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Transcription factors associated with Nfe2l2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfe2l2 | rn6_v1_chr3_-_62524996_62524996 | -0.38 | 5.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_166943592 Show fit | 0.50 |
ENSRNOT00000026962
|
folate receptor 1 |
|
| chr1_-_88881460 Show fit | 0.25 |
ENSRNOT00000028287
|
hematopoietic cell signal transducer |
|
| chr11_+_87435185 Show fit | 0.22 |
ENSRNOT00000002558
|
purinergic receptor P2X 6 |
|
| chr2_+_115362799 Show fit | 0.18 |
ENSRNOT00000015756
|
ribosomal protein L22 like 1 |
|
| chr4_-_44136815 Show fit | 0.17 |
ENSRNOT00000086810
|
transcription factor EC |
|
| chr14_-_115052450 Show fit | 0.17 |
ENSRNOT00000067998
|
acylphosphatase 2 |
|
| chr13_-_90602365 Show fit | 0.16 |
ENSRNOT00000009344
|
calsequestrin 1 |
|
| chr2_+_24546536 Show fit | 0.16 |
ENSRNOT00000014036
|
orthopedia homeobox |
|
| chr11_+_45304068 Show fit | 0.15 |
ENSRNOT00000031464
|
cms1 ribosomal small subunit homolog (yeast) |
|
| chr3_-_2490392 Show fit | 0.14 |
ENSRNOT00000014993
|
SS nuclear autoantigen 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nfe2l2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0060974 | cell migration involved in heart formation(GO:0060974) |
| 0.0 | 0.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.2 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.0 | 0.1 | GO:2000468 | regulation of peroxidase activity(GO:2000468) |
| 0.0 | 0.1 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.0 | 0.1 | GO:0097069 | cellular response to thyroxine stimulus(GO:0097069) |
| 0.0 | 0.1 | GO:0000053 | argininosuccinate metabolic process(GO:0000053) |
| 0.0 | 0.1 | GO:0070814 | hydrogen sulfide biosynthetic process(GO:0070814) |
| 0.0 | 0.1 | GO:0031989 | bombesin receptor signaling pathway(GO:0031989) |
| 0.0 | 0.1 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.5 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 0.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.2 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.2 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.1 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.1 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 0.5 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.0 | 0.2 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.0 | 0.1 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.0 | 0.1 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.0 | 0.1 | GO:0004946 | bombesin receptor activity(GO:0004946) |
| 0.0 | 0.1 | GO:0017098 | UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.0 | 0.1 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 0.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.1 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |