Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

Navigation
Downloads

Results for Nfe2l2

Z-value: 0.54

Motif logo

Transcription factors associated with Nfe2l2

Gene Symbol Gene ID Gene Info
ENSRNOG00000001548 nuclear factor, erythroid 2-like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfe2l2rn6_v1_chr3_-_62524996_62524996-0.385.3e-01Click!

Activity profile of Nfe2l2 motif

Sorted Z-values of Nfe2l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_166943592 0.50 ENSRNOT00000026962
folate receptor 1
chr1_-_88881460 0.25 ENSRNOT00000028287
hematopoietic cell signal transducer
chr11_+_87435185 0.22 ENSRNOT00000002558
purinergic receptor P2X 6
chr2_+_115362799 0.18 ENSRNOT00000015756
ribosomal protein L22 like 1
chr4_-_44136815 0.17 ENSRNOT00000086810
transcription factor EC
chr14_-_115052450 0.17 ENSRNOT00000067998
acylphosphatase 2
chr13_-_90602365 0.16 ENSRNOT00000009344
calsequestrin 1
chr2_+_24546536 0.16 ENSRNOT00000014036
orthopedia homeobox
chr11_+_45304068 0.15 ENSRNOT00000031464
cms1 ribosomal small subunit homolog (yeast)
chr3_-_2490392 0.14 ENSRNOT00000014993
SS nuclear autoantigen 1
chr2_+_225827504 0.13 ENSRNOT00000018343
glutamate cysteine ligase, modifier subunit
chr8_+_76426335 0.13 ENSRNOT00000085496
general transcription factor2A subunit 2
chr6_+_128738388 0.13 ENSRNOT00000050204
ribosomal protein L6, pseudogene 1
chr3_+_103747654 0.13 ENSRNOT00000006887
NOP10 ribonucleoprotein
chr17_-_53102342 0.13 ENSRNOT00000073834
proteasome subunit alpha 2
chr2_-_196415530 0.13 ENSRNOT00000064238
similar to hypothetical protein FLJ20519
chr10_-_61576952 0.12 ENSRNOT00000092712
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
chr10_+_84309430 0.11 ENSRNOT00000030159
src kinase associated phosphoprotein 1
chr1_-_219294147 0.11 ENSRNOT00000024601
glutathione S-transferase pi 1
chr11_+_30363280 0.10 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr1_-_88123643 0.10 ENSRNOT00000027937
proteasome 26S subunit, non-ATPase 8
chr15_-_33263659 0.10 ENSRNOT00000018005
proteasome subunit beta 5
chr17_-_14687408 0.10 ENSRNOT00000088542

chr16_+_23317953 0.10 ENSRNOT00000075287

chr13_-_36101411 0.09 ENSRNOT00000074471
transmembrane protein 37
chr5_+_135536413 0.09 ENSRNOT00000023132
peroxiredoxin 1
chr5_+_57947716 0.09 ENSRNOT00000067657
dynein, axonemal, intermediate chain 1
chr3_-_10371240 0.09 ENSRNOT00000012075
argininosuccinate synthase 1
chr7_+_119626637 0.09 ENSRNOT00000000201
mercaptopyruvate sulfurtransferase
chr3_-_175426395 0.09 ENSRNOT00000082686
proteasome subunit alpha 7
chr6_-_42302254 0.09 ENSRNOT00000007071
PQ loop repeat containing 3
chr20_+_295250 0.09 ENSRNOT00000000955
chloride intracellular channel 2
chr7_+_79138925 0.08 ENSRNOT00000047511

chr6_+_93423002 0.08 ENSRNOT00000010753
proteasome subunit alpha 3
chr15_+_4351292 0.08 ENSRNOT00000009207
mitochondrial ribosomal protein S16
chrX_+_159505344 0.08 ENSRNOT00000001164
bombesin receptor subtype 3
chr7_+_59200918 0.08 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr19_+_37282018 0.08 ENSRNOT00000021723
transmembrane protein 208
chrX_+_28593405 0.08 ENSRNOT00000071708
thymosin beta 4, X-linked
chr8_+_133029625 0.07 ENSRNOT00000008809
C-C motif chemokine receptor 3
chr9_+_17817721 0.07 ENSRNOT00000086986
ENSRNOT00000026920
heat shock protein 90 alpha family class B member 1
chr4_+_3043231 0.07 ENSRNOT00000013732
interleukin 6
chr4_+_66670618 0.07 ENSRNOT00000010796
thromboxane A synthase 1
chr6_+_76188083 0.07 ENSRNOT00000009666
proteasome subunit alpha 6
chr4_+_176994129 0.07 ENSRNOT00000018734
cytidine monophosphate N-acetylneuraminic acid synthetase
chr11_+_53081025 0.07 ENSRNOT00000002700
BBX, HMG-box containing
chr11_-_76888178 0.07 ENSRNOT00000049841
osteocrin
chr1_-_170318935 0.07 ENSRNOT00000024119
protein kinase C, delta binding protein
chr18_-_1216379 0.07 ENSRNOT00000020537
ENSRNOT00000084613
ubiquitin specific peptidase 14
chr8_-_13290773 0.07 ENSRNOT00000012217
similar to RIKEN cDNA 1700012B09
chr1_-_57489727 0.07 ENSRNOT00000002037
proteasome subunit beta 1
chr3_+_2490518 0.06 ENSRNOT00000015099
anaphase promoting complex subunit 2
chr1_+_87066289 0.06 ENSRNOT00000027645
calpain 12
chr7_+_2479311 0.06 ENSRNOT00000003787
prostaglandin E synthase 3
chr17_+_53102534 0.06 ENSRNOT00000021433
mitochondrial ribosomal protein L32
chr1_+_101324652 0.06 ENSRNOT00000028116
histidine rich calcium binding protein
chr9_+_15166118 0.06 ENSRNOT00000020432
MyoD family inhibitor
chr2_+_211050360 0.06 ENSRNOT00000026928
proteasome subunit alpha 5
chr4_-_28953067 0.06 ENSRNOT00000013989
tissue factor pathway inhibitor 2
chr10_+_95706685 0.05 ENSRNOT00000004283
proteasome 26S subunit, non-ATPase 12
chr5_+_144701949 0.05 ENSRNOT00000015618
proteasome subunit beta 2
chr6_-_128690741 0.05 ENSRNOT00000035826
spectrin repeat containing, nuclear envelope family member 3
chr1_-_183744586 0.05 ENSRNOT00000015946
proteasome subunit alpha 1
chr11_-_83944763 0.05 ENSRNOT00000002358
proteasome 26S subunit, non-ATPase 2
chr6_-_26051229 0.05 ENSRNOT00000005855
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr19_+_19395655 0.05 ENSRNOT00000019130
sorting nexin 20
chr14_+_22091777 0.05 ENSRNOT00000072483
sulfotransferase family 1D, member 1
chr2_+_46980976 0.05 ENSRNOT00000083668
ENSRNOT00000082990
molybdenum cofactor synthesis 2
chr19_-_43848937 0.05 ENSRNOT00000044844
lactate dehydrogenase D
chr18_-_59086251 0.05 ENSRNOT00000025510
ENSRNOT00000083831
thioredoxin-like 1
chr15_+_2526368 0.05 ENSRNOT00000048713
ENSRNOT00000074803
dual specificity phosphatase 13
dual specificity phosphatase 13
chr3_-_159802952 0.05 ENSRNOT00000011610
oxidative stress responsive serine-rich 1
chr1_-_225128740 0.05 ENSRNOT00000026897
retinal outer segment membrane protein 1
chr13_+_60545635 0.04 ENSRNOT00000077153
ubiquitin C-terminal hydrolase L5
chr8_-_115179191 0.04 ENSRNOT00000017224
poly (ADP-ribose) polymerase family, member 3
chr1_-_198232344 0.04 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr17_-_70481750 0.04 ENSRNOT00000025252
interleukin 15 receptor subunit alpha
chr15_-_30174197 0.04 ENSRNOT00000074419
T-cell receptor alpha chain V region PHDS58-like
chr11_-_84037938 0.04 ENSRNOT00000002327
ATP binding cassette subfamily F member 3
chr7_-_120919261 0.04 ENSRNOT00000019612
Josephin domain containing 1
chr7_+_2737765 0.04 ENSRNOT00000004895
canopy FGF signaling regulator 2
chr7_+_64768742 0.04 ENSRNOT00000005545
glutamate receptor interacting protein 1
chr3_-_5483239 0.04 ENSRNOT00000071754
surfeit 4
chr4_+_157511642 0.04 ENSRNOT00000065846
PILR alpha associated neural protein
chr19_-_39646693 0.04 ENSRNOT00000019104
proteasome 26S subunit, non-ATPase 7
chr15_-_35113678 0.04 ENSRNOT00000059677
cathepsin G
chr8_+_33514042 0.04 ENSRNOT00000081614
ENSRNOT00000081525
potassium voltage-gated channel subfamily J member 1
chr2_-_187854363 0.04 ENSRNOT00000092993
lamin A/C
chr10_+_46906115 0.03 ENSRNOT00000034006
alkB homolog 5, RNA demethylase
chr13_+_27889345 0.03 ENSRNOT00000079134
ENSRNOT00000003274
serpin family B member 8
chr15_+_31141142 0.03 ENSRNOT00000060304
uncharacterized LOC103693854
chr8_+_80965255 0.03 ENSRNOT00000079508
WD repeat domain 72
chr3_+_79876938 0.03 ENSRNOT00000015757
proteasome 26S subunit, ATPase 3
chr1_-_222734184 0.03 ENSRNOT00000049812
ENSRNOT00000028785
reticulon 3
chrX_-_31968152 0.03 ENSRNOT00000004884
pirin
chr11_-_86328469 0.03 ENSRNOT00000071493
ubiquitin fusion degradation 1 like (yeast)
chr13_+_92264231 0.03 ENSRNOT00000066509
ENSRNOT00000004716
spectrin, alpha, erythrocytic 1
chr6_-_99843245 0.03 ENSRNOT00000080270
glutathione peroxidase 2
chrX_-_72034099 0.03 ENSRNOT00000004310
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr10_-_63240332 0.03 ENSRNOT00000005125
bleomycin hydrolase
chr17_-_66511870 0.03 ENSRNOT00000044662
galectin 8
chr18_+_55666027 0.03 ENSRNOT00000045950
similar to CDNA sequence BC023105
chr1_+_12915734 0.03 ENSRNOT00000089066
taxilin beta
chr8_-_130550388 0.03 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr3_+_146365092 0.03 ENSRNOT00000008865
cystatin F
chr2_-_190100276 0.03 ENSRNOT00000015351
S100 calcium binding protein A9
chr19_+_52077501 0.02 ENSRNOT00000079240
oxidative stress induced growth inhibitor 1
chr2_-_238246931 0.02 ENSRNOT00000086303
glutathione S-transferase, C-terminal domain containing
chr6_-_49089855 0.02 ENSRNOT00000006526
thyroid peroxidase
chr1_+_85337805 0.02 ENSRNOT00000026839
sterile alpha motif domain containing 4B
chr11_+_86797557 0.02 ENSRNOT00000083049
ENSRNOT00000046594
transport and golgi organization 2 homolog
chrX_+_17171605 0.02 ENSRNOT00000048236
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr7_+_10937599 0.02 ENSRNOT00000008758
sirtuin 6
chr16_-_14382641 0.02 ENSRNOT00000018723
growth hormone inducible transmembrane protein
chr11_-_81660395 0.02 ENSRNOT00000048739
fetuin B
chr5_-_101006375 0.02 ENSRNOT00000014008
cerberus 1, DAN family BMP antagonist
chr4_+_162392869 0.02 ENSRNOT00000047790
C-type lectin domain family 2, member D
chr18_-_76984203 0.02 ENSRNOT00000089122
CTD phosphatase subunit 1
chr4_+_163293724 0.02 ENSRNOT00000077356
GABA type A receptor associated protein like 1
chr10_+_46018659 0.02 ENSRNOT00000040865
ENSRNOT00000004357
myosin phosphatase Rho interacting protein
chr20_+_5527181 0.02 ENSRNOT00000091364
PHD finger protein 1
chr10_+_94445877 0.02 ENSRNOT00000013997
proteasome 26S subunit, ATPase 5
chr20_-_41209728 0.02 ENSRNOT00000000657
5'-nucleotidase domain containing 1
chr7_-_121058029 0.02 ENSRNOT00000068033
chromobox 6
chr9_-_13513960 0.02 ENSRNOT00000067626
molybdenum cofactor synthesis 1
chr3_+_152294656 0.02 ENSRNOT00000027067
PHD finger protein 20
chr5_-_145418992 0.02 ENSRNOT00000037128
gap junction protein, beta 4
chr15_+_44411865 0.02 ENSRNOT00000017566
potassium channel tetramerization domain containing 9
chr5_-_167244786 0.02 ENSRNOT00000051309
carbonic anhydrase 6
chr3_+_160231914 0.01 ENSRNOT00000014411
potassium two pore domain channel subfamily K member 15
chr8_-_28075514 0.01 ENSRNOT00000072851
VPS26 retromer complex component B
chr13_-_85443727 0.01 ENSRNOT00000090668
ENSRNOT00000076125
uridine-cytidine kinase 2
chr17_-_9791781 0.01 ENSRNOT00000090536
regulator of G-protein signaling 14
chr5_-_58445953 0.01 ENSRNOT00000046102
valosin-containing protein
chr19_+_38422164 0.01 ENSRNOT00000017174
NAD(P)H quinone dehydrogenase 1
chr4_+_7314369 0.01 ENSRNOT00000029724
autophagy related 9B
chr15_+_32832035 0.01 ENSRNOT00000060250

chr19_+_45946236 0.01 ENSRNOT00000045250
synaptonemal complex central element protein 1-like
chr19_+_52077109 0.01 ENSRNOT00000020225
oxidative stress induced growth inhibitor 1
chr16_-_62239987 0.01 ENSRNOT00000020252
glutathione-disulfide reductase
chrX_+_104734082 0.01 ENSRNOT00000005020
sushi-repeat-containing protein, X-linked 2
chr9_+_51298426 0.01 ENSRNOT00000065212
GULP, engulfment adaptor PTB domain containing 1
chr5_-_150994913 0.01 ENSRNOT00000075506
similar to RIKEN cDNA 2900010J23
chr8_+_45797315 0.01 ENSRNOT00000059997

chr9_-_99659425 0.01 ENSRNOT00000051686
olfactory receptor 1343
chr8_+_119228612 0.01 ENSRNOT00000078439
ENSRNOT00000043737
leucine rich repeat containing 2
chr1_-_165997751 0.01 ENSRNOT00000050227
pyrimidinergic receptor P2Y6
chr17_-_9792007 0.01 ENSRNOT00000021596
regulator of G-protein signaling 14
chr5_+_64294321 0.01 ENSRNOT00000083796
Myb/SANT DNA binding domain containing 3
chr10_+_105499569 0.01 ENSRNOT00000088457
sphingosine kinase 1
chr1_+_199248470 0.01 ENSRNOT00000025933
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr12_-_52676608 0.01 ENSRNOT00000072507
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr3_-_2456041 0.00 ENSRNOT00000062001
ring finger protein 224
chr20_+_3987230 0.00 ENSRNOT00000088615
transporter 1, ATP binding cassette subfamily B member
chr1_+_199360645 0.00 ENSRNOT00000026527
lysine acetyltransferase 8
chr3_+_2648885 0.00 ENSRNOT00000020339
ATP binding cassette subfamily A member 2
chr19_-_37281933 0.00 ENSRNOT00000059663
leucine rich repeat containing 29
chr20_+_5526975 0.00 ENSRNOT00000059548
PHD finger protein 1
chr16_-_20383337 0.00 ENSRNOT00000025977
interleukin 12 receptor subunit beta 1
chrX_-_142248369 0.00 ENSRNOT00000091330
fibroblast growth factor 13
chr15_-_4035064 0.00 ENSRNOT00000012300
fucosyltransferase 11
chr3_-_122920684 0.00 ENSRNOT00000028818
carboxypeptidase X (M14 family), member 1
chr8_-_23282989 0.00 ENSRNOT00000019204
zinc finger protein 717
chr1_+_199555722 0.00 ENSRNOT00000054983
integrin subunit alpha X

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2l2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.1 GO:0000053 argininosuccinate metabolic process(GO:0000053)
0.0 0.1 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:2000660 negative regulation of chemokine biosynthetic process(GO:0045079) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0097332 response to antipsychotic drug(GO:0097332)
0.0 0.1 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.0 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.0 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253) negative regulation of interleukin-8 secretion(GO:2000483)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0017098 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G