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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Nfatc3
Z-value: 0.53
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Transcription factors associated with Nfatc3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfatc3 | rn6_v1_chr19_+_38039564_38039564 | 0.28 | 6.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_138148967 Show fit | 0.23 |
ENSRNOT00000033968
|
FERM domain containing 7 |
|
| chr3_-_107760550 Show fit | 0.19 |
ENSRNOT00000077091
ENSRNOT00000051638 |
Meis homeobox 2 |
|
| chr12_-_51965779 Show fit | 0.19 |
ENSRNOT00000056733
|
replication protein A3-like |
|
| chr8_+_127144903 Show fit | 0.18 |
ENSRNOT00000013530
|
eomesodermin |
|
| chr10_-_74769637 Show fit | 0.18 |
ENSRNOT00000008889
|
zinc finger protein OZF-like |
|
| chr16_+_35573058 Show fit | 0.18 |
ENSRNOT00000059580
|
polypeptide N-acetylgalactosaminyltransferase-like 6 |
|
| chr10_-_32471454 Show fit | 0.18 |
ENSRNOT00000003224
|
sarcoglycan, delta |
|
| chr17_-_51912496 Show fit | 0.18 |
ENSRNOT00000019272
|
inhibin beta A subunit |
|
| chr18_+_30890869 Show fit | 0.15 |
ENSRNOT00000060466
|
protocadherin gamma subfamily B, 6 |
|
| chr14_-_112946204 Show fit | 0.15 |
ENSRNOT00000056813
|
coiled-coil domain-containing protein 85A-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nfatc3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.0 | 0.2 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.0 | 0.1 | GO:1902214 | regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.0 | 0.1 | GO:0034628 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.0 | 0.1 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.0 | 0.1 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
| 0.0 | 0.1 | GO:1900060 | negative regulation of ceramide biosynthetic process(GO:1900060) |
| 0.0 | 0.1 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.0 | 0.1 | GO:0035711 | T-helper 1 cell activation(GO:0035711) |
| 0.0 | 0.1 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0043511 | inhibin complex(GO:0043511) |
| 0.0 | 0.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.0 | 0.1 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.0 | 0.1 | GO:0070421 | DNA ligase III-XRCC1 complex(GO:0070421) |
| 0.0 | 0.1 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 0.1 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 0.1 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 0.0 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.0 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.0 | 0.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 0.1 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.0 | 0.1 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.0 | GO:0008458 | carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414) |
| 0.0 | 0.0 | GO:0030977 | taurine binding(GO:0030977) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.1 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |