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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nfatc1

Z-value: 1.07

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSRNOG00000017146 nuclear factor of activated T-cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1rn6_v1_chr18_-_77322690_773226900.592.9e-01Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_137934484 0.75 ENSRNOT00000049046
hypothetical protein LOC317588
chr20_-_22459025 0.66 ENSRNOT00000000792
early growth response 2
chr13_+_29839867 0.60 ENSRNOT00000090623

chr2_+_149899836 0.50 ENSRNOT00000086481
similar to hypothetical protein C130079G13
chr13_+_41802697 0.47 ENSRNOT00000046719
LRRGT00155-like
chr1_-_4560789 0.46 ENSRNOT00000082415
androglobin
chr1_+_168668707 0.46 ENSRNOT00000015108

chr17_+_48436720 0.44 ENSRNOT00000074309

chr1_+_1545134 0.44 ENSRNOT00000044523

chr2_-_112368557 0.44 ENSRNOT00000075017

chr7_-_99808612 0.41 ENSRNOT00000074953

chr10_-_36419926 0.41 ENSRNOT00000004902
zinc finger protein 354B
chr1_+_254531659 0.40 ENSRNOT00000091377

chr2_+_118746333 0.37 ENSRNOT00000079431

chr3_+_95614562 0.36 ENSRNOT00000079990

chr2_+_70490155 0.34 ENSRNOT00000078674

chr2_+_11658568 0.33 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chr18_-_77322690 0.33 ENSRNOT00000058382
nuclear factor of activated T-cells 1
chr12_-_13374500 0.33 ENSRNOT00000038577
zinc finger protein 12
chr10_+_83655460 0.30 ENSRNOT00000008011
G protein subunit gamma transducin 2
chr3_-_123849788 0.29 ENSRNOT00000028869
ring finger protein 24
chr2_+_216863428 0.28 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr14_+_39663421 0.28 ENSRNOT00000003197
gamma-aminobutyric acid type A receptor alpha2 subunit
chr8_-_84632817 0.28 ENSRNOT00000076942
muscular LMNA-interacting protein
chr4_-_157433467 0.27 ENSRNOT00000028965
lymphocyte activating 3
chr5_-_8864578 0.27 ENSRNOT00000008480
centrosome and spindle pole associated protein 1
chr5_+_27326762 0.27 ENSRNOT00000066191
RUNX1 translocation partner 1
chr13_+_67351087 0.26 ENSRNOT00000003567
prostaglandin-endoperoxide synthase 2
chr7_-_98098268 0.26 ENSRNOT00000010361
F-box protein 32
chrX_-_31851715 0.25 ENSRNOT00000068601
vascular endothelial growth factor D
chr18_-_1389929 0.25 ENSRNOT00000051362
Rho-associated coiled-coil containing protein kinase 1
chr18_-_1390190 0.24 ENSRNOT00000061777
Rho-associated coiled-coil containing protein kinase 1
chr7_+_48867664 0.23 ENSRNOT00000005862
PTPRF interacting protein alpha 2
chr18_+_30864216 0.23 ENSRNOT00000027015
protocadherin gamma subfamily A, 7
chrX_+_114929029 0.23 ENSRNOT00000006459
p21 (RAC1) activated kinase 3
chr1_-_62316450 0.22 ENSRNOT00000079171

chr1_-_266914093 0.22 ENSRNOT00000027526
calcium homeostasis modulator 2
chr2_+_54191538 0.22 ENSRNOT00000019524
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_+_19866408 0.21 ENSRNOT00000060465
ADAM metallopeptidase with thrombospondin type 1, motif 3
chr11_+_61531416 0.21 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr1_-_128341240 0.21 ENSRNOT00000070864
ENSRNOT00000072915
myocyte enhancer factor 2a
chr1_+_88885937 0.21 ENSRNOT00000029719
NFKB inhibitor delta
chr1_+_44311513 0.20 ENSRNOT00000065386
T-cell lymphoma invasion and metastasis 2
chr9_+_43889473 0.20 ENSRNOT00000024330
inositol polyphosphate-4-phosphatase type I A
chr4_+_120672152 0.20 ENSRNOT00000077231
monoglyceride lipase
chr7_-_134495835 0.20 ENSRNOT00000058349
glucoside xylosyltransferase 1
chr5_-_160352927 0.20 ENSRNOT00000017247
DnaJ heat shock protein family (Hsp40) member C16
chr9_-_81772851 0.19 ENSRNOT00000032719
ubiquitin specific peptidase 37
chr14_+_109533792 0.19 ENSRNOT00000067690
ankyrin repeat domain-containing protein 29-like
chr18_+_65155685 0.19 ENSRNOT00000081797
transcription factor 4
chr13_-_113817995 0.19 ENSRNOT00000057151
CD46 molecule
chr3_+_58164931 0.19 ENSRNOT00000002078
distal-less homeobox 1
chrY_+_327166 0.18 ENSRNOT00000092902
sex determining region Y
chr9_+_67699379 0.18 ENSRNOT00000091237
ENSRNOT00000088183
cytotoxic T-lymphocyte-associated protein 4
chr16_-_70705128 0.18 ENSRNOT00000071258
ring finger protein 170
chr13_-_82005741 0.18 ENSRNOT00000076404
methyltransferase like 11B
chr3_-_64024205 0.17 ENSRNOT00000037015
coiled-coil domain containing 141
chr17_-_27665266 0.17 ENSRNOT00000060218
ras responsive element binding protein 1
chr13_-_67688477 0.17 ENSRNOT00000068148
proteoglycan 4
chr15_-_33250546 0.17 ENSRNOT00000017857
similar to RIKEN cDNA 4931414P19
chr2_+_22910236 0.17 ENSRNOT00000078266
homer scaffolding protein 1
chr10_+_34489940 0.17 ENSRNOT00000085975
zinc finger protein 62
chr12_-_19294888 0.17 ENSRNOT00000001815
zinc finger protein 3
chr16_+_70859280 0.17 ENSRNOT00000019630
protein-O-mannose kinase
chr1_+_224998172 0.17 ENSRNOT00000026321
zinc finger and BTB domain containing 3
chr5_-_59647633 0.17 ENSRNOT00000091944
ring finger protein 38
chr1_+_255185629 0.17 ENSRNOT00000083002
HECT domain E3 ubiquitin protein ligase 2
chr4_-_42188289 0.16 ENSRNOT00000081688
RNA binding motif protein, X-linked-like 1B
chr8_+_2604962 0.16 ENSRNOT00000009993
caspase 1
chrX_+_18163358 0.16 ENSRNOT00000045517
similar to Spindlin-like protein 2 (SPIN-2)
chr18_+_29386809 0.16 ENSRNOT00000082079
ENSRNOT00000024825
eukaryotic translation initiation factor 4E binding protein 3
chr2_-_183031214 0.16 ENSRNOT00000013260
similar to RIKEN cDNA D930015E06
chr16_+_35116440 0.16 ENSRNOT00000074353

chr9_+_73433252 0.16 ENSRNOT00000092540
microtubule-associated protein 2
chr12_-_29743705 0.16 ENSRNOT00000001185
calneuron 1
chr17_-_51912496 0.16 ENSRNOT00000019272
inhibin beta A subunit
chr2_+_150756185 0.16 ENSRNOT00000088461
ENSRNOT00000036808
muscleblind-like splicing regulator 1
chr8_+_99880073 0.16 ENSRNOT00000010765
phospholipid scramblase 4
chr5_-_59553416 0.16 ENSRNOT00000090490
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr5_-_160383782 0.16 ENSRNOT00000018349
chymotrypsin-like elastase family, member 2A
chr5_-_160070916 0.16 ENSRNOT00000067517
ENSRNOT00000055791
spen family transcriptional repressor
chr1_+_190681094 0.15 ENSRNOT00000036175
von Willebrand factor A domain containing 3A
chr7_-_36408588 0.15 ENSRNOT00000063946
CASP2 and RIPK1 domain containing adaptor with death domain
chr5_-_60191941 0.15 ENSRNOT00000033373
paired box 5
chr3_+_8451292 0.15 ENSRNOT00000020407
outer dense fiber of sperm tails 2
chr13_-_89545182 0.15 ENSRNOT00000078402
Purkinje cell protein 4-like 1
chr13_-_73819896 0.15 ENSRNOT00000036392
family with sequence similarity 163, member A
chr9_-_32019205 0.15 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr1_+_171797516 0.14 ENSRNOT00000088110
PPFIA binding protein 2
chr2_-_89498395 0.14 ENSRNOT00000068507

chr16_+_70778913 0.14 ENSRNOT00000019281
hook microtubule-tethering protein 3
chr3_-_71845232 0.14 ENSRNOT00000078645
calcitonin receptor like receptor
chr18_+_70427007 0.14 ENSRNOT00000087959
ENSRNOT00000019512
myosin Vb
chr1_+_213583606 0.14 ENSRNOT00000088899

chrX_-_38196060 0.14 ENSRNOT00000006741
ENSRNOT00000006438
SH3 domain-containing kinase-binding protein 1
chr6_-_107325345 0.14 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
NUMB, endocytic adaptor protein
chr7_+_40217991 0.13 ENSRNOT00000085684
centrosomal protein 290
chr18_+_30036887 0.13 ENSRNOT00000077824
protocadherin alpha 4
chr8_-_39551700 0.13 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr11_-_71128299 0.13 ENSRNOT00000080568
forty-two-three domain containing 1
chr9_-_98597359 0.13 ENSRNOT00000027506
period circadian clock 2
chr8_+_76400341 0.13 ENSRNOT00000087382
ENSRNOT00000081072
BCL2/adenovirus E1B interacting protein 2
chr1_+_228684136 0.13 ENSRNOT00000028608
olfactory receptor 337
chr5_-_58484900 0.13 ENSRNOT00000012386
family with sequence similarity 214, member B
chr15_+_39779648 0.13 ENSRNOT00000084505
calcium binding protein 39-like
chr2_-_39007976 0.12 ENSRNOT00000064292
zinc finger, SWIM-type containing 6
chr6_+_83421882 0.12 ENSRNOT00000084258
leucine rich repeat and fibronectin type III domain containing 5
chr17_-_44640092 0.12 ENSRNOT00000077628
zinc finger protein 184
chr6_-_42616548 0.12 ENSRNOT00000081433
ATPase H+ transporting V1 subunit C2
chr5_-_173653905 0.12 ENSRNOT00000038556
pleckstrin homology domain containing N1
chr5_+_150833819 0.12 ENSRNOT00000056170
EYA transcriptional coactivator and phosphatase 3
chr5_-_147761983 0.12 ENSRNOT00000012936
LCK proto-oncogene, Src family tyrosine kinase
chr17_+_53231343 0.12 ENSRNOT00000021703
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr12_-_41266430 0.12 ENSRNOT00000001853
ENSRNOT00000081108
2-5 oligoadenylate synthetase 1B
chr7_+_130532435 0.11 ENSRNOT00000092672
ENSRNOT00000092535
SH3 and multiple ankyrin repeat domains 3
chr5_+_120498883 0.11 ENSRNOT00000007859
leptin receptor overlapping transcript
chr5_+_74766636 0.11 ENSRNOT00000030913

chr4_-_124338176 0.11 ENSRNOT00000016628
prickle planar cell polarity protein 2
chr3_+_170550314 0.11 ENSRNOT00000006991
transcription factor AP-2 gamma
chr10_+_95770154 0.11 ENSRNOT00000030300
helicase with zinc finger
chr11_-_65208837 0.11 ENSRNOT00000003867
glycogen synthase kinase 3 beta
chr17_+_36334147 0.11 ENSRNOT00000050261
E2F transcription factor 3
chr10_+_49259194 0.11 ENSRNOT00000091100
ENSRNOT00000004390
F-box and WD repeat domain containing 10
chr18_+_30890869 0.11 ENSRNOT00000060466
protocadherin gamma subfamily B, 6
chr1_+_190462327 0.11 ENSRNOT00000030732
similar to ankyrin repeat domain 26
chr15_-_57805184 0.11 ENSRNOT00000000168
component of oligomeric golgi complex 3
chr10_-_84847857 0.11 ENSRNOT00000071495
migration and invasion enhancer 1-like
chr3_-_67787990 0.10 ENSRNOT00000064851
NCK-associated protein 1
chr15_-_33428942 0.10 ENSRNOT00000019618
ENSRNOT00000092160
solute carrier family 7 member 8
chr6_+_137063611 0.10 ENSRNOT00000017504
hypothetical protein LOC691485
chr10_+_84669914 0.10 ENSRNOT00000011665
chromobox 1
chr2_-_112802073 0.10 ENSRNOT00000093081
epithelial cell transforming 2
chr1_+_198655742 0.10 ENSRNOT00000023944
myosin light chain, phosphorylatable, fast skeletal muscle
chr6_+_143901280 0.10 ENSRNOT00000091884
ENSRNOT00000005648
zinc finger protein 386 (Kruppel-like)
chr18_+_30562178 0.10 ENSRNOT00000040998
protocadherin beta-16-like
chr2_+_187893875 0.10 ENSRNOT00000093014
mex-3 RNA binding family member A
chr5_-_88612626 0.10 ENSRNOT00000089560
transducin like enhancer of split 1
chr11_+_61661724 0.10 ENSRNOT00000079423
zinc finger, DHHC-type containing 23
chr10_+_68588789 0.10 ENSRNOT00000049614

chr3_-_150960030 0.10 ENSRNOT00000024714
nuclear receptor coactivator 6
chr1_+_151439409 0.10 ENSRNOT00000022060
ENSRNOT00000050639
glutamate metabotropic receptor 5
chr15_+_32811135 0.10 ENSRNOT00000067689

chr20_-_27657983 0.10 ENSRNOT00000057313
family with sequence similarity 26, member E
chr3_-_153246433 0.10 ENSRNOT00000067748
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr4_+_22084954 0.09 ENSRNOT00000090968
carnitine O-octanoyltransferase
chr18_+_30023828 0.09 ENSRNOT00000079008
protocadherin alpha 4
chr6_+_10348308 0.09 ENSRNOT00000034991
endothelial PAS domain protein 1
chr10_-_38969501 0.09 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr13_+_50164563 0.09 ENSRNOT00000029533
lymphocyte transmembrane adaptor 1
chr3_+_100786862 0.09 ENSRNOT00000080190
brain-derived neurotrophic factor
chr7_+_41114697 0.09 ENSRNOT00000041354
ATPase plasma membrane Ca2+ transporting 1
chr10_-_83655182 0.09 ENSRNOT00000007897
ABI family, member 3
chr1_-_6903486 0.09 ENSRNOT00000086574
utrophin
chr3_+_100787449 0.09 ENSRNOT00000078543
brain-derived neurotrophic factor
chr6_-_50943488 0.09 ENSRNOT00000068419
dihydrouridine synthase 4-like
chr13_+_50434886 0.09 ENSRNOT00000076857
SRY box 13
chr11_+_38727048 0.09 ENSRNOT00000081537
zinc finger protein 260-like
chr15_+_41448064 0.09 ENSRNOT00000019551
sacsin molecular chaperone
chr16_+_6962722 0.09 ENSRNOT00000023330
musculoskeletal, embryonic nuclear protein 1
chr6_+_64789940 0.09 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr13_+_50434702 0.08 ENSRNOT00000032244
SRY box 13
chr11_+_88699222 0.08 ENSRNOT00000084177
FYVE, RhoGEF and PH domain containing 4
chr1_-_276308095 0.08 ENSRNOT00000054681
zinc finger, DHHC-type containing 6
chr10_+_56193856 0.08 ENSRNOT00000080584
ENSRNOT00000091216
ENSRNOT00000083458
tumor protein p53
chr17_+_89951752 0.08 ENSRNOT00000057572
ENSRNOT00000091023
abl-interactor 1
chr9_-_105655471 0.08 ENSRNOT00000014921
similar to 2610034M16Rik protein
chr7_-_36499784 0.08 ENSRNOT00000011948
suppressor of cytokine signaling 2
chr14_-_44225713 0.08 ENSRNOT00000049161
similar to ribosomal protein L14
chr1_-_25839198 0.08 ENSRNOT00000090388
ENSRNOT00000092757
ENSRNOT00000042072
triadin
chr18_+_750776 0.08 ENSRNOT00000021981
zinc finger protein 136
chr5_+_142797366 0.08 ENSRNOT00000031928
metal-regulatory transcription factor 1
chr8_-_114449956 0.08 ENSRNOT00000056414
collagen type VI alpha 6 chain
chr15_+_23777856 0.08 ENSRNOT00000060847
sterile alpha motif domain containing 4A
chr16_+_75145401 0.08 ENSRNOT00000046821
ENSRNOT00000047761
sperm associated antigen 11b-like
chr12_+_41200718 0.08 ENSRNOT00000038426
ENSRNOT00000048450
ENSRNOT00000067176
2'-5' oligoadenylate synthetase 1A
chr4_+_181055662 0.08 ENSRNOT00000086813
serine/threonine kinase 38 like
chr3_+_129462738 0.08 ENSRNOT00000077755

chr1_+_98627372 0.08 ENSRNOT00000030370
zinc finger protein 17
chr9_-_44237117 0.08 ENSRNOT00000068496
similar to putative protein (5S487)
chr3_+_172692452 0.08 ENSRNOT00000077193
zinc finger protein 831
chr5_+_135351816 0.08 ENSRNOT00000082602
intracisternal A particle-promoted polypeptide
chr4_-_125929002 0.08 ENSRNOT00000083271
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_-_105214989 0.08 ENSRNOT00000037895
gremlin 1, DAN family BMP antagonist
chr2_+_243502073 0.08 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_27620458 0.08 ENSRNOT00000059532
similar to FLJ25323 protein
chr1_+_63842277 0.07 ENSRNOT00000087957
ENSRNOT00000080820
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A
chr20_+_48212378 0.07 ENSRNOT00000040519

chr15_+_104026601 0.07 ENSRNOT00000013520
ENSRNOT00000083269
ENSRNOT00000093403
claudin 10
chr10_+_1920529 0.07 ENSRNOT00000072296
RIKEN cDNA A630010A05 gene
chr6_-_39363367 0.07 ENSRNOT00000088687
ENSRNOT00000065531
family with sequence similarity 84, member A
chr4_+_9981958 0.07 ENSRNOT00000015322
N-acyl phosphatidylethanolamine phospholipase D
chr6_+_18880737 0.07 ENSRNOT00000003432
alkB homolog 8, tRNA methyltransferase
chr16_-_81028656 0.07 ENSRNOT00000091296
defective in cullin neddylation 1 domain containing 2
chr11_+_42945084 0.07 ENSRNOT00000002292
crystallin beta-gamma domain containing 3
chr10_-_15928169 0.07 ENSRNOT00000028069
neuron specific gene family member 2
chr7_+_11356118 0.07 ENSRNOT00000041325
ATCAY, caytaxin
chr8_-_36374673 0.07 ENSRNOT00000013763
decapping enzyme, scavenger
chr20_-_5153399 0.07 ENSRNOT00000001133
proline-rich coiled-coil 2A
chr14_-_90864917 0.07 ENSRNOT00000044737
LRRGT00197
chr10_+_36589181 0.07 ENSRNOT00000045596
zinc finger protein 354A

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.1 0.6 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:2001013 positive regulation of macrophage apoptotic process(GO:2000111) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.2 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.2 GO:0046380 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:1904339 cellular response to iron(II) ion(GO:0071282) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:1903660 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.1 GO:1900158 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.0 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0033552 response to vitamin B3(GO:0033552)
0.0 0.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.2 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.0 0.2 GO:0061193 taste bud development(GO:0061193)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730) positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.1 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.0 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.0 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.0 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.1 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.0 0.0 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.5 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.0 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.2 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0030977 taurine binding(GO:0030977)
0.0 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.0 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.7 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762) vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors