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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nanog

Z-value: 0.31

Motif logo

Transcription factors associated with Nanog

Gene Symbol Gene ID Gene Info
ENSRNOG00000008368 Nanog homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nanogrn6_v1_chr4_+_155531906_1555319060.345.7e-01Click!

Activity profile of Nanog motif

Sorted Z-values of Nanog motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_123106694 0.26 ENSRNOT00000028829
oxytocin/neurophysin 1 prepropeptide
chr4_+_171250818 0.14 ENSRNOT00000040576
protein tyrosine phosphatase, receptor type, O
chr1_+_87066289 0.10 ENSRNOT00000027645
calpain 12
chr8_+_72743426 0.09 ENSRNOT00000072573
ribosomal protein S27-like
chr2_+_187447501 0.09 ENSRNOT00000038589
IQ motif containing GTPase activating protein 3
chr1_-_168972725 0.09 ENSRNOT00000090422
hemoglobin subunit beta
chr4_-_178168690 0.08 ENSRNOT00000020729
SRY box 5
chr3_+_44025300 0.08 ENSRNOT00000006319
polypeptide N-acetylgalactosaminyltransferase 5
chr2_-_138833933 0.08 ENSRNOT00000013343
protocadherin 18
chrX_-_138148967 0.08 ENSRNOT00000033968
FERM domain containing 7
chr7_-_143497108 0.08 ENSRNOT00000048613
keratin 76
chr5_+_144031402 0.07 ENSRNOT00000011694
colony stimulating factor 3 receptor
chr7_-_28715224 0.07 ENSRNOT00000065899
PARP1 binding protein
chr19_+_14345993 0.07 ENSRNOT00000084913
predicted gene, 18025
chr9_+_20241062 0.07 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr5_-_136098013 0.07 ENSRNOT00000089166
RGD1563714
chr9_+_81644355 0.06 ENSRNOT00000071700
ciliogenesis associated TTC17 interacting protein
chr17_-_51912496 0.06 ENSRNOT00000019272
inhibin beta A subunit
chr2_+_208750356 0.06 ENSRNOT00000041562
chitinase, acidic
chr18_+_81694808 0.06 ENSRNOT00000020446
cytochrome b5 type A
chr15_+_12827707 0.06 ENSRNOT00000012452
Fez family zinc finger 2
chr8_+_39687269 0.06 ENSRNOT00000012060
transmembrane protein 218
chr1_+_91363492 0.06 ENSRNOT00000014517
CCAAT/enhancer binding protein alpha
chr3_+_150761329 0.05 ENSRNOT00000067854
dynein light chain roadblock-type 1
chr4_-_170912629 0.05 ENSRNOT00000055691
endoplasmic reticulum protein 27
chr2_+_54466280 0.05 ENSRNOT00000033112
complement C6
chr3_+_100768637 0.05 ENSRNOT00000083542
brain-derived neurotrophic factor
chr10_-_15098791 0.05 ENSRNOT00000026139
chromosome transmission fidelity factor 18
chr1_-_216663720 0.05 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr7_+_77066955 0.05 ENSRNOT00000008700
outer dense fiber of sperm tails 1
chr17_-_78735324 0.05 ENSRNOT00000036299
cerebral dopamine neurotrophic factor
chr7_-_54855557 0.05 ENSRNOT00000039475
GLI pathogenesis-related 1 like 1
chr19_-_10450186 0.05 ENSRNOT00000088048
adhesion G protein-coupled receptor G1
chrX_+_13441558 0.05 ENSRNOT00000030170
similar to Ferritin light chain (Ferritin L subunit)
chr3_-_161294125 0.05 ENSRNOT00000021143
spermatogenesis associated 25
chr6_-_47904163 0.05 ENSRNOT00000011333
ribosomal protein S7
chr10_-_89005213 0.05 ENSRNOT00000027159
PSMC3 interacting protein
chr17_-_42031265 0.05 ENSRNOT00000068021
doublecortin domain containing 2
chr10_+_89635675 0.05 ENSRNOT00000028179
similar to SAP18
chr3_+_138174054 0.04 ENSRNOT00000007946
barrier to autointegration factor 2
chr7_+_140054592 0.04 ENSRNOT00000014337
olfactory receptor 1108
chrX_-_142164220 0.04 ENSRNOT00000064780
fibroblast growth factor 13
chr2_-_219262901 0.04 ENSRNOT00000037068
G-protein coupled receptor 88
chrM_+_5323 0.04 ENSRNOT00000050156
mitochondrially encoded cytochrome c oxidase 1
chr10_+_59566223 0.04 ENSRNOT00000024068
ENSRNOT00000088245
purinergic receptor P2X 1
chr20_+_27592379 0.04 ENSRNOT00000047000
trafficking protein particle complex 3-like
chr7_-_143228060 0.04 ENSRNOT00000088923
ENSRNOT00000012640
keratin 75
chr16_+_2706428 0.04 ENSRNOT00000077117
interleukin 17 receptor D
chrX_+_123751293 0.04 ENSRNOT00000089883
NFKB activating protein
chrX_-_115496045 0.04 ENSRNOT00000051134
ribosomal protein S26-like
chr7_+_112057030 0.04 ENSRNOT00000035216

chr9_-_55673704 0.04 ENSRNOT00000066231
ENSRNOT00000081677
transmembrane protein with EGF-like and two follistatin-like domains 2
chr6_+_132551394 0.04 ENSRNOT00000019583
Enah/Vasp-like
chr2_-_244370983 0.04 ENSRNOT00000021458
Rap1 GTPase-GDP dissociation stimulator 1
chr10_-_87541851 0.04 ENSRNOT00000089610
similar to keratin associated protein 2-4
chrX_-_106607352 0.04 ENSRNOT00000082858

chrX_+_105147534 0.04 ENSRNOT00000046288
centromere protein I
chr10_+_105498728 0.04 ENSRNOT00000032163
sphingosine kinase 1
chr20_+_5374985 0.04 ENSRNOT00000052270
RT1 class Ia, locus A2
chr1_+_82473737 0.04 ENSRNOT00000028029
B9 protein domain 2
chr7_+_24939498 0.04 ENSRNOT00000010601
cytoskeleton-associated protein 4
chr10_+_45297937 0.04 ENSRNOT00000066367
tripartite motif-containing 17
chr9_-_82336806 0.04 ENSRNOT00000024667
solute carrier family 23, member 3
chr14_-_21709084 0.04 ENSRNOT00000087477
submaxillary gland androgen regulated protein 3B
chrX_+_123751089 0.04 ENSRNOT00000092384
NFKB activating protein
chr2_+_189609800 0.03 ENSRNOT00000089016
solute carrier family 39 member 1
chr8_-_115145810 0.03 ENSRNOT00000079470
abhydrolase domain containing 14A
chr1_-_178367828 0.03 ENSRNOT00000050823

chr2_+_208749996 0.03 ENSRNOT00000086321
chitinase, acidic
chr1_-_255557055 0.03 ENSRNOT00000033780
fibroblast growth factor binding protein 3
chr5_+_139038134 0.03 ENSRNOT00000078155
human immunodeficiency virus type I enhancer binding protein 3
chr5_-_115387377 0.03 ENSRNOT00000036030
ENSRNOT00000077492
similar to hypothetical protein MGC34837
chr7_+_34326087 0.03 ENSRNOT00000006971
histidine ammonia lyase
chr4_-_155401480 0.03 ENSRNOT00000020735
apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr1_+_247869756 0.03 ENSRNOT00000054764
melan-A
chr14_+_23480462 0.03 ENSRNOT00000002755
gonadotropin releasing hormone receptor
chr1_+_170147300 0.03 ENSRNOT00000048075
olfactory receptor 200
chr2_-_250778269 0.03 ENSRNOT00000085670
ENSRNOT00000083535
ENSRNOT00000017824
chloride channel accessory 5
chr7_+_29435444 0.03 ENSRNOT00000008613
solute carrier family 5 member 8
chr9_+_61552374 0.03 ENSRNOT00000050090
transmembrane protein 258 B
chr4_+_110699557 0.03 ENSRNOT00000030588
ENSRNOT00000092261
leucine rich repeat transmembrane neuronal 4
chr10_+_34402482 0.03 ENSRNOT00000072317
putative olfactory receptor
chr14_-_104612597 0.03 ENSRNOT00000007002
solute carrier family 1 member 4
chr3_+_67849966 0.03 ENSRNOT00000057826
dual specificity phosphatase 19
chr4_+_163174487 0.03 ENSRNOT00000088108
C-type lectin domain family 9, member A
chr20_+_26999795 0.03 ENSRNOT00000057872
myopalladin
chr8_+_48699769 0.03 ENSRNOT00000044613
hypoxia up-regulated 1
chr7_-_136853957 0.03 ENSRNOT00000008985
neural EGFL like 2
chr9_+_12740885 0.03 ENSRNOT00000015210
raftlin lipid raft linker 1
chr19_-_10212050 0.03 ENSRNOT00000082822
testis, prostate and placenta expressed
chr6_+_8669722 0.03 ENSRNOT00000048550
calmodulin-lysine N-methyltransferase
chr9_+_27068443 0.03 ENSRNOT00000017393
EF-hand domain containing 1
chr5_-_155709215 0.03 ENSRNOT00000018118
cell division cycle 42
chr2_+_216863428 0.03 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr9_+_74124016 0.03 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr6_+_22696397 0.03 ENSRNOT00000011630
anaplastic lymphoma receptor tyrosine kinase
chr3_+_72080630 0.03 ENSRNOT00000008911
mediator complex subunit 19
chrX_+_136466779 0.03 ENSRNOT00000093268
ENSRNOT00000068717
Rho GTPase activating protein 36
chr2_+_60461551 0.03 ENSRNOT00000024557
RAD1 checkpoint DNA exonuclease
chr3_-_23020441 0.03 ENSRNOT00000017651
nuclear receptor subfamily 5, group A, member 1
chr2_-_112831476 0.03 ENSRNOT00000018055
epithelial cell transforming 2
chr8_-_116391158 0.03 ENSRNOT00000078720
ENSRNOT00000022550
G protein subunit alpha i2
chr5_+_172364421 0.03 ENSRNOT00000018769
hes family bHLH transcription factor 5
chr3_+_147511563 0.03 ENSRNOT00000006828
solute carrier family 52 member 3
chr20_+_4178686 0.03 ENSRNOT00000080641
testis specific basic protein
chr19_-_27535792 0.03 ENSRNOT00000024040
olfactory receptor 1666
chr1_-_1889236 0.03 ENSRNOT00000087944

chr19_-_28645488 0.03 ENSRNOT00000044160

chr9_+_43259709 0.03 ENSRNOT00000022487
cytochrome c oxidase subunit 5B
chr3_+_114918648 0.03 ENSRNOT00000089204
sulfide quinone reductase-like (yeast)
chr7_-_60294796 0.03 ENSRNOT00000007580
YEATS domain containing 4
chrX_-_123708211 0.03 ENSRNOT00000092456
ribosomal protein L39
chr3_-_127500709 0.03 ENSRNOT00000006330
hydroxyacid oxidase 1
chr1_+_215610368 0.03 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr1_-_64021321 0.03 ENSRNOT00000090819
ribosomal protein S9
chr1_-_100231460 0.03 ENSRNOT00000032200
acid phosphatase, testicular
chr1_+_64162672 0.03 ENSRNOT00000089713
TCF3 (E2A) fusion partner
chr5_+_98387291 0.03 ENSRNOT00000046503
tyrosinase-related protein 1
chr13_+_47935163 0.03 ENSRNOT00000006768
eukaryotic translation initiation factor 2D
chr8_-_128711221 0.03 ENSRNOT00000055888
xin actin-binding repeat containing 1
chr19_-_25378974 0.03 ENSRNOT00000011150
coiled-coil domain containing 130
chr8_+_55504857 0.03 ENSRNOT00000088320
BTG anti-proliferation factor 4
chr3_-_46601409 0.03 ENSRNOT00000079261
phospholipase A2 receptor 1
chr8_+_55037750 0.03 ENSRNOT00000013188
translocase of inner mitochondrial membrane 8 homolog B
chrX_+_77065397 0.03 ENSRNOT00000090007
cytochrome c oxidase subunit 7B
chr2_-_118882562 0.02 ENSRNOT00000058860
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr5_-_154332940 0.02 ENSRNOT00000014458
PITH domain containing 1
chr8_-_72204730 0.02 ENSRNOT00000023810
F-box and leucine-rich repeat protein 22
chr9_-_23493081 0.02 ENSRNOT00000072144
Rh-associated glycoprotein
chr10_+_45966926 0.02 ENSRNOT00000067584
olfactory receptor 225
chr5_-_141430659 0.02 ENSRNOT00000034944
akirin 1
chr10_-_34333305 0.02 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr4_-_34282351 0.02 ENSRNOT00000011123
replication protein A3
chrM_+_9451 0.02 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr5_-_24631679 0.02 ENSRNOT00000010846
ENSRNOT00000067129
epithelial splicing regulatory protein 1
chr15_-_52320385 0.02 ENSRNOT00000067776
dematin actin binding protein
chr8_-_132919110 0.02 ENSRNOT00000008747
X-C motif chemokine receptor 1
chr1_+_101214593 0.02 ENSRNOT00000028086
TEA domain transcription factor 2
chr17_-_62299655 0.02 ENSRNOT00000024855
gap junction protein, delta 4
chr8_+_117455262 0.02 ENSRNOT00000027520
solute carrier family 25 member 20
chr1_+_222844144 0.02 ENSRNOT00000032879
phospholipase A2, group XVI
chr10_+_43851950 0.02 ENSRNOT00000085666
similar to Robo-1
chr4_+_153805993 0.02 ENSRNOT00000056174
ubiquitin specific peptidase 18
chr5_-_101166651 0.02 ENSRNOT00000078862
Fras1 related extracellular matrix 1
chr10_-_90151042 0.02 ENSRNOT00000055187
histone deacetylase 5
chr1_-_19376301 0.02 ENSRNOT00000015547
Rho GTPase activating protein 18
chr11_-_32550539 0.02 ENSRNOT00000002715
regulator of calcineurin 1
chr1_+_177569618 0.02 ENSRNOT00000090042
TEA domain transcription factor 1
chr5_+_59008933 0.02 ENSRNOT00000023060
carbonic anhydrase 9
chr13_-_90977734 0.02 ENSRNOT00000011869
SLAM family member 8
chr16_+_71738718 0.02 ENSRNOT00000022097
pleckstrin homology domain containing A2
chr14_-_19072677 0.02 ENSRNOT00000060548
similar to alpha-fetoprotein
chr1_-_89014189 0.02 ENSRNOT00000028413
lin-37 DREAM MuvB core complex component
chr9_-_99299715 0.02 ENSRNOT00000027622
histone deacetylase 4
chr11_+_87549059 0.02 ENSRNOT00000002567
coiled-coil domain containing 74A
chr10_+_68588789 0.02 ENSRNOT00000049614

chr2_-_195279218 0.02 ENSRNOT00000085565
similar to TDPOZ3
chr5_+_33097654 0.02 ENSRNOT00000008087
cyclic nucleotide gated channel beta 3
chr13_-_48927483 0.02 ENSRNOT00000010976
cyclin-dependent kinase 18
chr19_-_29134876 0.02 ENSRNOT00000040545

chr3_-_147263275 0.02 ENSRNOT00000029620
proteasome inhibitor subunit 1
chr7_+_78649875 0.02 ENSRNOT00000006243
dendrocyte expressed seven transmembrane protein
chr7_-_134722215 0.02 ENSRNOT00000036750
prickle planar cell polarity protein 1
chrX_-_1346181 0.02 ENSRNOT00000042736
60S ribosomal protein L12-like
chr4_-_170740274 0.02 ENSRNOT00000012212
guanylate cyclase 2C
chr10_+_49231730 0.02 ENSRNOT00000065335
tripartite motif-containing 16
chr1_+_60717386 0.02 ENSRNOT00000015019
protein phosphatase 2 scaffold subunit A alpha
chr10_+_62303662 0.02 ENSRNOT00000056355
TLC domain containing 2
chr8_-_49502647 0.02 ENSRNOT00000040313
transmembrane protease, serine 4
chr11_+_76147205 0.02 ENSRNOT00000071586
fibroblast growth factor 12
chr1_-_100234040 0.02 ENSRNOT00000079199
acid phosphatase, testicular
chr5_+_33784715 0.02 ENSRNOT00000035685
solute carrier family 7 member 13
chrX_-_23139694 0.02 ENSRNOT00000033656
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr16_-_47535358 0.02 ENSRNOT00000040731
claudin 22
chr4_-_138830117 0.02 ENSRNOT00000008403
interleukin 5 receptor subunit alpha
chr14_+_45062662 0.02 ENSRNOT00000059124
toll-like receptor 10
chr20_+_26534535 0.02 ENSRNOT00000000423
transmembrane protein 167B
chr3_-_147481073 0.02 ENSRNOT00000084722
family with sequence similarity 110, member A
chr10_+_31324512 0.02 ENSRNOT00000008559
fibronectin type III domain containing 9
chr5_+_154668179 0.02 ENSRNOT00000015971
heterogeneous nuclear ribonucleoprotein R
chr4_+_118167294 0.02 ENSRNOT00000022367
similar to small nuclear ribonucleoprotein polypeptide G
chr2_-_179704629 0.02 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr5_-_151768123 0.02 ENSRNOT00000079380
nuclear distribution C, dynein complex regulator
chr19_+_54314865 0.02 ENSRNOT00000024069
interferon regulatory factor 8
chr19_-_14945302 0.02 ENSRNOT00000079391

chr7_+_60015998 0.02 ENSRNOT00000007309
bestrophin 3
chr17_+_2690062 0.02 ENSRNOT00000024937
olfactory receptor 1653
chr8_-_48672732 0.02 ENSRNOT00000079275
hydroxymethylbilane synthase
chr7_-_58343137 0.02 ENSRNOT00000005310
ENSRNOT00000090560
transmembrane protein 19
chr16_-_31972507 0.02 ENSRNOT00000032199
carbonyl reductase 4
chr18_-_69944632 0.02 ENSRNOT00000047271
mitogen-activated protein kinase 4
chr15_-_9086282 0.02 ENSRNOT00000008989
thyroid hormone receptor beta
chr13_+_99335020 0.02 ENSRNOT00000029787

chrX_-_152932953 0.02 ENSRNOT00000078929
centrin 2
chr8_+_115069095 0.02 ENSRNOT00000014770
dual specificity phosphatase 7
chr3_+_117421604 0.02 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chr20_-_157665 0.02 ENSRNOT00000048858
ENSRNOT00000079494
RT1 class I, locus CE10
chr1_-_214511529 0.02 ENSRNOT00000026390
chitinase domain containing 1
chr2_+_178679041 0.02 ENSRNOT00000013524
family with sequence similarity 198, member B
chr1_+_189432604 0.02 ENSRNOT00000034610
acyl-CoA synthetase medium-chain family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Nanog

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0 0.1 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.1 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.0 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of forebrain neuron differentiation(GO:2000978)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:2000741 regulation of timing of neuron differentiation(GO:0060164) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.0 0.0 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.0 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.0 0.0 GO:0060661 submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.0 GO:0090648 response to environmental enrichment(GO:0090648)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.0 GO:0008481 sphinganine kinase activity(GO:0008481)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)