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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Mzf1
Z-value: 0.80
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Transcription factors associated with Mzf1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mzf1 | rn6_v1_chr1_+_65522118_65522118 | 0.28 | 6.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_109300433 Show fit | 0.44 |
ENSRNOT00000010712
|
FBJ osteosarcoma oncogene |
|
| chr10_-_85574889 Show fit | 0.42 |
ENSRNOT00000072274
|
hypothetical protein LOC691153 |
|
| chr7_+_70364813 Show fit | 0.40 |
ENSRNOT00000084012
ENSRNOT00000031230 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
|
| chr2_+_210381829 Show fit | 0.39 |
ENSRNOT00000024611
|
ALX homeobox 3 |
|
| chr7_+_142912316 Show fit | 0.36 |
ENSRNOT00000010171
|
nuclear receptor subfamily 4, group A, member 1 |
|
| chr9_+_17841410 Show fit | 0.26 |
ENSRNOT00000031706
|
transmembrane protein 151B |
|
| chr2_+_196334626 Show fit | 0.25 |
ENSRNOT00000050914
ENSRNOT00000028645 ENSRNOT00000090729 |
semaphorin 6C |
|
| chrX_+_76786466 Show fit | 0.23 |
ENSRNOT00000090665
|
fibroblast growth factor 16 |
|
| chr2_-_77632628 Show fit | 0.22 |
ENSRNOT00000073915
|
brain abundant, membrane attached signal protein 1 |
|
| chr19_+_59328960 Show fit | 0.22 |
ENSRNOT00000086865
|
cytochrome c oxidase assembly factor 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Mzf1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.1 | 0.4 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.0 | 0.4 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.0 | 0.4 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
| 0.1 | 0.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.1 | 0.2 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.1 | 0.2 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.0 | 0.2 | GO:0070346 | positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.0 | 0.2 | GO:0060751 | branch elongation involved in mammary gland duct branching(GO:0060751) |
| 0.0 | 0.2 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 0.1 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.0 | 0.1 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.0 | 0.1 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.1 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.1 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.0 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.0 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 0.2 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.0 | 0.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.2 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.0 | 0.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.1 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375) |
| 0.0 | 0.1 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.0 | 0.1 | GO:0016403 | dimethylargininase activity(GO:0016403) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.2 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.2 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |